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"ABSTRACTEconomic growth and urbanization have changed global dietary habits and caused nutrition transitionglobally. Urban people, especially in developing countries, eat away from home, consuming more polishedgrains, fats and animal product, refined sugar and processed foods compared to rural people (Helman,2000). The change in consumption pattern which leads to nutritional change, in the long run, may beharmful for health of the people, including adolescents. Some studies indicate the change in consumptionpattern among the adolescents worldwide. The change in eating habits among young people due to somechronic diseases, are allegedly caused by adolescence’s unhealthy diet. A survey of middle and high schoolstudents in Minnesota shows that the youth consume more calories from fast food meals; they havedifficulty getting healthy food as there is higher proportion of unhealthy food, therefore making themprone to being overweight (Widome, Neumark‐Sztainer, Hannan, Haines, & Story, 2009). A qualitativestudy that identifies barriers to healthy eating among second level schools across Ireland showed thataggressive marketing by fast food franchises draw adolescents to these outlets although they know it isunhealthy; youth have autonomy over their eating behaviour and tend to eat unhealthily once they areindependent (Stevenson, Doherty, Barnett, Muldoon, & Trew, 2007)."

"Gizi lebih merupakan kondisi tubuh dengan berat badan yang berlebih dibandingkan dengan usia atau tinggi badan akibat asupan gizi relatif melebihi jumlah yang diperlukan untuk pertumbuhan normal, perkembangan, dan metabolisme. Gizi lebih merupakan masalah kesehatan masyarakat karena berhubungan dengan meningkatnya risiko terjadinya kesakitan dan kematian. Tujuan umum penelitian ini adalah diketahuinya hubungan antara kebiasaan makan (frekuensi makan, kebiasaan minum susu dan hasil olahannya, kebiasaan makan fast food, kebiasaan makan jajanan, kebiasaan makan camilan saat menonton TV) dan durasi menonton TV dengan gizi lebih pada anak usia prasekolah. Penelitian ini merupakan studi cross-sectional terhadap 148 anak usia prasekolah dari 2 sekolah di Garut. Pengukuran berat dan tinggi badan anak dilakukan oleh petugas sedangkan informasi karakteristik anak dan orang tua, kebiasaan makan dan aktivitas fisik anak diperoleh melalui kuesioner yang diisi oleh responden sendiri. Pengolahan dan analisis data menggunakan uji chi-square (bivariat) dan regresi logistik ganda (multivariat). Hasil analisis menunjukkan bahwa berdasarkan indeks IMT/U prevalensi gizi lebih (kelebihan berat dan kegemukan) anak prasekolah mencapai 25,7%. Ada hubungan antara frekuensi makan, kebiasaan minum susu, kebiasaan makan fast food, kebiasaan makan camilan saat menonton TV, dan durasi menonton TV dengan gizi lebih anak prasekolah. Frekuensi makan utama merupakan faktor yang dominan berhubungan dengan gizi lebih setelah dikontrol variabel kebiasaan makan fast food, kebiasaan minum susu, durasi menonton TV dan status pekerjaan ibu dalam analisis multivariat.

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Overnutrition is the condition of body with excess weight compared with age or height due to oversupplied of nutrients relative to the amounts required for normal growth, development, and metabolism. Overnutrition is a public health issue because it deals with an increased risk of morbidity and mortality. The general objective of this research is to know the relationship between eating habits (frequency of eating, milk-drinking habits, fast food eating habits, snack eating, habits of snacking while watching TV), and duration of watching TV with overnutrition in preschoolers.

This was a cross-sectional study of 148 preschoolaged children from two kindergarden in Garut. A measurement of children`s heights and weights were collected by trained personnel, while the information characteristics of children and parents, childrens eating habits and physical activities were collected from self-administered questioner. Processing and analyzing data using chi-square test (bivariate) and multiple logistic regression (multivariate).

The analysis showed that based on the index BMI/age, prevalence rates of overnutrition (overweight and obesity) were 25,7%. The results of chisquare tes showed significant relationship between overnutrition with frequency of eating, milk-drinking habits, fast food eating habits, habits of snacking while watching TV and duration of watching TV. Frequency of eating variable is the dominant factor associated with overnutrition after being controlled by fast food eating habits, milk-drinking habits, duration of watching TV and maternal employment status in the multivariate analysis."

"ABSTRAKTujuan penelitian ini adalah untuk mengetahui pengaruh pemberian teh hijauterhadap stres oksidatif postprandial pasca asupan makanan tinggi lemak padaindividu dewasa muda sehat. Penelitian ini merupakan studi eksperimental dengandesain alokasi acak menyilang tersamar tunggal yang melibatkan 19 orangsubyek, 8 laki-laki dan 11 perempuan, dengan median usia 20 tahun (19–21tahun). Subyek penelitian diberikan 6 g teh hijau dalam 300 mL air atau airputih setelah mengonsumsi burger dengan total energi 1066 kkal dan komposisilemak 57,71% pada dua kesempatan yang berbeda. Kadar MDA plasma diukurpada awal dan 2 jam setelah mengonsumsi makanan dan minuman yangdiberikan. Median perubahan kadar MDA plasma pada pemberian teh hijauadalah 0,04 (-0,19–0,11) dan rerata perubahan kadar MDA plasma pada pemberianair putih adalah 0,01 ± 0,04. Tidak didapatkan perbedaan bermakna perubahankadar MDA plasma 2 jam postprandial antara pemberian teh hijau dibandingkandengan pemberian air putih (p=0,296). Pada penelitian ini dapat disimpulkanbahwa konsumsi teh hijau dosis tunggal pasca asupan makanan tinggi lemak tidakmemberikan penurunan stres oksidatif postprandial pada individu dewasa mudasehat.

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ABSTRACTThe objective of this study was to evaluate the ability of green tea cathecins tomodify postprandial oxidative stress after a high-fat meal in healthy young adults.This is a randomized, single-blind, placebo-controlled trial which involved 19subjects, 8 men and 11 women, with median age 20 years (19–21 years) Afterconsuming a high-fat burger (1066 kcal with 57,71% fat), subjects were given 6 ggreen tea in 300 ml water or drinking water on two separate occasions. Bloodsamples were collected pre-meal (fasted) and 120 min post meal, and assayed forplasma malondialdehyde (MDA). Median changes of MDA concentration aftergreen tea was 0,04 (-0,19–0,11) and mean changes of MDA concentration afterdrinking water was 0,01 ± 0,04. There was no significant difference of MDAconcentration changes between green tea and drinking water. The data indicatethat consuming single dose green tea after a high-fat meal could not attenuatepostprandial oxidative stress in healthy young adult."

"Penelitian ini bertujuan untuk mengetahui gambaran dari status gizi dan faktor-faktor yang berhubungan dengan status gizi tersebut pada siswi di SMPN 200 Jakarta. Penelitian ini menggunakan metode cross-sectional dan pengambilan sampel secara random berkelompok (cluster sampling). Pengambilan data penelitian dilakukan pada April 2013 dan menggunakan instrumen penelitian berupa timbangan, microtoise, dan kuesioner. Sampel penelitian ini terdiri dari 160 siswi kelas 7 dan 8 dan dianalasis dengan menggunakan uji chi-square. Hasil Penelitian ini menunjukkan bahwa sebanyak 15,6% responden memiliki status gizi kurus. Penelitian ini juga menemukan bahwa status gizi berhubungan secara signifikan dengan citra tubuh (p-value 0.000), frekuensi makan utama (p-value 0.007), dan konsumsi makan pagi (p-value 0.001). Disarankan adanya program edukasi gizi seperti pelatihan penilaian status gizi dan penyuluhan tentang status gizi agar remaja putri dapat menilai status gizinya secara akurat dan tidak salah dalam mempersepsikan citra tubuhnya.

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The aim of this study was to determine the percentage of nutritional status and its correlates among students (adolescent girls) at SMPN 200 Jakarta. This study used cross-sectional design and cluster sampling method. This study was conducted on April 2013 used scale, microtoise and questionnaire. The study sample consisted of 160 students of class 7 and 8 and analyzed using the chi- square test.

The result of this study shows that 15,6% of respondents classiffied as thinness. This study also found that nutritional status has been associated with body image (p-value 0.000), eating frequancy (p-value 0.007), and breakfast behaviour (p-value 0.001).

The researcher suggests the existence of nutrition education programs such as training about nutritional status assessment and counseling about nutritional status so that adolescent girls can assess the nutritional status accurately and not mistaken in perceiving their body image. "

"Prevalensi gizi lebih terus meningkat setiap tahunnya. Gizi lebih memiliki dampak serius bagi perkembangan penyakit tidak menular dan produktifitas. Penelitian ini bertujuan untuk mengetahui gambaran prevalensi gizi lebih dan faktor risiko dominan penyebab gizi lebih pada dewasa usia 20-59 tahun di Pusdiklat Buddhis Maitreyawira Jakarta. Penelitian ini dilakukan dengan desain studi cross-sectional pada 157 responden. Pengambilan data dilakukan pada bulan April-Mei 2015 dengan metode purposive sampling. Hasil penelitian menunjukkan prevalensi gizi lebih di lokasi penelitian sebesar 28%. Dari hasil analisis bivariat diketahui adanya hubungan bermakna antara gizi lebih dengan jenis diet, usia, status pernikahan, aktivitas fisik, pengetahuan gizi, asupan energi dan asupan lemak (p value < 0,05). Walaupun tidak bermakna secara statistik, responden dengan status gizi lebih cenderung memiliki skor kualitas diet yang rendah. Dari hasil analisis multivariat dengan uji regresi logistik ganda, diketahui asupan energi merupakan faktor dominan gizi lebih (OR = 19,743) pada dewasa setelah dikontrol variabel usia, jenis kelamin, status pernikahan, aktivitas fisik, pengetahuan gizi, asupan karbohidrat, asupan protein, asupan lemak dan kualitas diet. Perlu dilakukan intervensi kepada pihak terkait di lokasi penelitian untuk mengurangi dan mengatasi kejadian gizi lebih.

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Prevalence of overnutrition increased over year. Overnutrition had serious impact to development of non communicable disease and decrease productivity. This purpose of this study was to describe the prevalence of overnutrition and to find which of the risk factor is the dominant factor that is related to overnutrition in adult 20-59 years old at Pusdiklat Buddhis Maitreyawira Jakarta. This study was conducted with cross-sectional study design with 157 respondents. The data were collected during April-May 2015 with purposive sampling method. The results showed that overnutrition prevalence was 28%. Although there was no significant relationship between diet quality and overnutrition, overweight/obese respondent tend to have lower diet quality score than another.

From bivariate analyses, there were significant relationship between overnutrition and vegetarian diet, age, marital status, physical activity, nutritional knowledge, energy intake, and fat intake (p value = 0,05). From multivariate analyses, we found that energy intake as a dominant factor which cause overnutrition in adult (OR = 19,743) after controlled with age, gender, marital status, physical activity, nutritional knowledge, carbohydrate intake, protein intake, fat intake and diet quality. Therefore, intervention to the related side at study location should be done to decrease and overcome overnutrition."

"ABSTRAKSarapan merupakan aktivitas penting bagi anak usia sekolah sebelum melakukankegiatannya. Penelitian ini bertujuan mengetahui hubungan upaya pemenuhan gizidengan kebiasaan sarapan pada anak usia sekolah dalam keluarga. Desaindeskriptif korelasi dengan pendekatan cross sectional dilakukan pada keluargayang memiliki anak usia sekolah. Hasil menunjukkan ada hubungan bermaknaantara pemenuhan gizi anak dengan kebiasaan sarapan dengan p value < α. Upayapemenuhan gizi meliputi penyediaan makanan, pemberian motivasi, perasaancinta dan model peran. Faktor yang paling dominan adalah model peran. Edukasikesehatan tentang pentingnya gizi pada anak usia sekolah perlu dilakukan sebagaiupaya promotif dan preventif.

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ABSTRACTBreakfast is an important activity for school-age children before making dailyactivities. This study aims to determine the relationship of nutrition fulfillmentwith breakfast habits of school-age children in the family. The descriptive designwith cross sectional correlation performed on families with school-age children.Result showed there is statistically significant association between nutritionfulfillment with breakfast habits (p value < α). These efforts include providingfood, giving motivation, feelings of love and role models. The most dominantfactor is role model. Health education on the importance of nutrition in school-agechildren needs to be done as promotion and prevention intervention."

"Penelitian ini bertujuan untuk mengetahui faktor dominan terhadap kecukupan asupan zat besi pada mahasiswa S-1 Reguler Angkatan 2013 Rumpun Ilmu Kesehatan Universitas Indonesia Tahun 2014. Desain yang digunakan adalah cross sectional, melibatkan 290 (perempuan=214; laki-laki=76) mahasiswa S-1 Reguler Angkatan 2013 RIK UI yang berusia 17-20 tahun pada April-Mei 2014. Metode pengambilan sampel adalah proporsional cluster random sampling. Pengumpulan data dilakukan melalui pengisian kuesioner dan wawancara asupan makanan 2x24 jam. Hasil penelitian menunjukan bahwa 83.8% responden tidak tercukupi kebutuhan zat besinya. Rata-rata asupan zat besi pada perempuan dan laki-laki adalah 12.3 mg/hari dan 16.0 mg/hari. Uji chi square menunjukan terdapat hubungan yang bermakna antara jenis kelamin (OR=7.56), perilaku konsumsi heme dan non heme (OR=2.86), konsumsi suplemen zat besi (OR=4.73), persepsi citra tubuh (OR=2.38), dan keterpaparan media massa (OR=3.01) terhadap kecukupan asupan zat besi. Analisis regresi logistik ganda menunjukan bahwa jenis kelamin (OR=19.17) dan konsumsi suplemen zat besi (OR=11.28) merupakan faktor dominan kecukupan asupan zat besi pada mahasiswa S-1 Reguler Angkatan 2013 RIK UI Tahun 2014.

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The objective of this study is to identify iron sufficiency's dominant factor among College Students of Health Sciences Program Batch 2013, Universitas Indonesia in 2014. This study used cross sectional design which conducted on 290 respondents (female=214; male=76) of college students of Health Sciences Program batch 2013, Universitas Indonesia, April-May 2014. Subjects aged in 17-20 years old and was performed by Proporsionate Cluster Random Sampling. Data were collected through the questionnaire and iron intake was obtained by 2x24 hours food recall. This study showed that 83.8% respondents who consumed iron unsufficient. Iron intake among female respondent was 12.3 mg/day and male was 16.0 mg/day. Chi Square Analysis showed significant relation between sex (OR=7.56), heme and non heme consumption (OR=2.86), iron supplement consumption (OR=4.73), body image (OR=2.38), and mass media (OR=3.01) with iron sufficiency. Regression Binary Logistic Analysis also showed that sex (OR=19.17) and iron supplement consumption (OR=11.28) as iron sufficiency's dominant factor among college students of Health Sciences Program Batch 2013, Universitas Indonesia in 2014."

"Perkembangan motorik merupakan salah satu aspek perkembangan penting bagi anak-anak karena melalui perkembangan motorik, anak mempelajari lingkungan dan memiliki pengalaman baru yang dapat menstimulasi hubungan di antara sel-sel saraf anak. Tujuan penelitian ini adalah untuk mengetahui gambaran perkembangan motorik serta faktor-faktor yang berhubungan dengan perkembangan motorik pada anak umur 7-36 bulan di Kelurahan Pademangan Barat, Jakarta Utara. Desain penelitian yaitu desain studi cross sectional, dengan sampel 134 anak berumur 7-36 bulan yang terdapat di Kelurahan Pademangan Barat, Jakarta Utara Bulan April-Mei 2014. Variabel yang diteliti meliputi stunting,wasting, asupan zat gizi (energi, protein, zat besi), ASI eksklusif, penyakit infeksi (diare dan ISPA), pengetahuan, serta stimulasi perkembangan sebagai variabel independen dan sebagai variabel dependen adalah perkembangan motorik. Pengumpulan data dilakukan melalui wawancara menggunakan kuesioner dan formulir food recall 2x24 jam, pengukuran antropometri berat badan dan tinggi badan, serta penilaian perkembangan motorik dengan formulir Denver II. Analisis statistik yang digunakan adalah uji chi square.Hasil penelitian menunjukkan bahwa anak-anak berumur 7-36 bulan yang mengalami keterlambatan perkembangan motorik di Kelurahan Pademangan Barat, Jakarta Utara berjumlah 17,2%. Hasil analisis bivariat menunjukkan terdapat hubungan yang bermakna antara severely stunting/ sangat pendek, wasting/ kurus, asupan energi, penyakit diare, serta stimulasi perkembangan dengan perkembangan motorik.Berdasarkan penelitian tersebut, setiap ibu balita serta anggota keluarga lainnya diharapkan dapat berperan mendukung tumbuh kembang anak dengan pemberian nutrisi, pemantauan status gizi, penerapan lingkungan sehat, dan pemberian stimulasi yang tepat. Selain itu, para petugas kesehatan diharapkan dapat meningkatkan edukasi kepada keluarga, khususnya para ibu balita tentang pentingnya pemantauan status gizi dan pemberian stimulasi perkembangan untuk anak.

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Motor development is one of the important aspect in children?s development. Through the attainment of motor skill, children start to explore their environment and engage with their new experiences that stimulate the neurogical synapses. This research purposed to analyze the relationship between stunting, wasting, nutition intake (energy, protein, iron), exclusive breastfeeding, infectious disease (diarrhea and acute respiratory infection), mother?s knowledge, and stimulation with motor development among children 7-36 months of age in Subdistrict of Pademangan Barat, North Jakarta.

This research used cross sectional study design with purposive sampling and 134 actual subjects in 7 maternal and children health care center in Subdistrict of Pademangan Barat, North Jakarta on April ? May 2014. The dependent variable is motor development and the independent variables are stunting, wasting, nutrition intake (energy, protein, iron), exclusive breastfeeding, infectious disease (diarrhea and acute respiratory infection), mother's knowledge, and stimulation. The data were collected through interview by using questionnaire and food recall sheet, anthropometric measurement (height and weight), and examine motor development by using Denver II sheet. Data analysis was performed using chi square test. The result showed that 17,2% of children have motor development delay.

The result of bivariate analysis showed that there was an association between severely stunting with children?s motor development. There were also significant association between wasting, energy intake, diarrhea, and stimulation with children?s motor development.

From this study, we suggest that mother and other family have to support the children?s development by providing adequate nutritious food, better stimulation, health environment, and maintaining nutritional status of the children. The health care workers are also required to provide and promote more information about children?s development for mother dan the family."

"Tujuan umum dari penelitian ini adalah mengetahui gambaran pola makan dan faktor lainnya serta hubungannya dengan status gizi TB/U (Z-score TB/U) pada balita (24-59 bulan) vegetarian dan non vegetarian di Jakarta tahun 2013. Penelitian ini merupakan penelitian deskriptif dengan desain studi cross-sectional menggunakan data primer terhadap 50 responden yang terdiri dari 25 balita vegetarian yang diambil dengan cara total sampling dan 25 balita non vegetarian dengan purposive sampling. Hasil penelitian menunjukkan proporsi balita pendek sebesar 8% pada vegetarian dan 4% pada non vegetarian dengan nilai rata-rata Z-score TB/U pada balita vegetarian sebesar -0,203 ± 0,954 dan pada balita non vegetarian sebesar -0,409 ± 0,877. Analisis bivariat menunjukkan tidak ada perbedaan yang signifikan antara status gizi TB/U pada balita vegetarian dan non vegetarian. Pada kelompok vegetarian, semakin tinggi frekuensi makan sayuran maka semakin rendah nilai Z-score TB/U dan semakin tinggi berat lahir semakin tinggi nilai Z-score TB/U. Pada balita non vegetarian, semakin tinggi frekuensi makan telur dan frekuensi makan sayuran maka semakin tinggi nilai Z-score TB/U. Peneliti menyarankan dilakukan pemberitahuan pada masyarakat bahwa balita yang menjalani diet vegetarian yang direncanakan dengan baik dapat tumbuh normal.

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The general objective of research was to know the eating patterns and other factors and their relationship to the HAZ nutritional status in vegetarian and non-vegetarian children (24-59 months) in Jakarta 2013. This research was a descriptive study with cross-sectional design that using primary data on 50 respondents consist of 25 vegetarian children who choosen by total sampling and 25 non vegetarian children by purposive sampling. The results showed the proportion of stunting is 8% on vegetarian children and 4% on non-vegetarian children with mean of HAZ -0,203 ± 0,954 on vegetarian children and -0,409 ± 0,877 on non-vegetarian children.

Bivariate analysis showed that there was not significant different HAZ nutritional status between vegetarian children and non vegetarian children. This study shows that in vegetarian children, the higher frequency of eating vegetables has lower HAZ and the higher birth weight has higher HAZ. Non vegetarian children showed that the higher frequency of eating eggs and frequency of eating vegetables has the higher HAZ. Researchers suggest to communicating with the public that children under five who have a good planned vegetarian diet can properly grow normally."

"[ABSTRAKLatar Belakang. Obat Anti Epilepsi (OAE) generasi lama banyak digunakan di Rumah Sakit sebagai terapi epilepsi. Beberapa studi terdahulu telah mengonfirmasi bahwa terapi OAE generasi lama terasosiasi dengan penurunan rerata kadar serum asam folat. Penurunan kadar serum asam folat ini berhubungan dengan anemia, defisit kognitif, penyakit vaskular, kanker, gangguan psikiatri, aborsi spontan dan malformasi kongenital. Oleh karena itu, maka dilakukan penelitian mengenai kadar serum folat pada ODE yang menggunakan OAE generasi lama di Indonesia. Metode. Desain penelitian adalah potong lintang untuk mengetahui gambaran kadar serum asam folat ODE pengguna OAE generasi lama (fenitoin, fenobarbital, karbamazepin dan asam valproat) jika dibandingkan dengan populasi normal serta kaitan dengan asupan. Subyek penelitian sejumlah 75 orang didapatkan di poli rawat jalan RSUPN Cipto Mangunkusumo dan Yayasan Epilepsi Indonesia yang dibandingkan dengan 76 orang populasi normal. Dilakukan wawancara pola makan melalui metode food recall, pemeriksaan laboratorium kadar folat. Hasil. Didapatkan kadar rerata serum asam folat sebesar 9.95 + 3.61 ng/mL pada ODE pengguna OAE generasi lama. Populasi normal didapatkan kadar rerata 4.59 + 2.4 ng/mL (p=<0.001). Rerata asupan diet setara folat kelompok studi 119.7 (28.4-340) microgram, kelompok kontrol 104.65 (38-510) microgram (p=0.095). Simpulan. Rerata kadar serum asam folat ODE yang menggunakan OAE generasi lama lebih tinggi dari rerata kadar serum asam folat populasi normal secara bermakna. Hanya terdapat 2,7% ODE dengan kadar asam folat rendah secara bermakna. Tidak ada perbedaan bermakna antara jumlah asupan diet folat dengan klasifikasi kadar serum asam folat pada ODE.

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ABSTRACTBackground. Antiepileptic drugs (AEDs) are frequently used in the treatment of epilepsy, psychiatric diseases, and pain syndromes. Studies have established that chronic anticonvulsant therapy can lead to folate deficiency. Anti-convulsant-induced folate deficiency has been associated with megaloblastic anemia, cognitive decline, vascular diseases, cancer, psychiatric comorbidity, spontaneous abortion and teratogenesis. Thus, patients with epilepsy are a suitable population to investigate the association of AED treatment with folate serum levels in comparison with normal population. Method. This is comparative cross-sectional study focusing on the level and intake of folate in relation with AED (phenytoin, phenobarbital, carbamazepine, valproic acid) in epileptic patients in outpatient clinic of Neurology Cipto Mangunkusumo General Hospital and Indonesia Epilepsy Foundation, with comparison to normal population. Seventy five epileptic patients and seventy six healthy people were recruited with food recall interview and their serum folate were measured. Results. The mean folate serum of study group were 9.95 + 3.61 ng/mL and the mean folate serum of control group were 4.59 + 2.4 ng/mL (p=<0.001). The mean dietary folate of study group were 119.7 (28.4-340) microgram and the mean dietary folate of control group 104.65 (38-510) microgram (p=0.095). Conclusion. The mean folate serum in study group were significant much more higher compare with the control group. As many as 2.7% of study group with significantly low folate serum level. There were no any significant association of dietary folate with folate serum classification of study group. ;Background.. Antiepileptic drugs (AEDs) are frequently used in the treatment of epilepsy, psychiatric diseases, and pain syndromes. Studies have established that chronic anticonvulsant therapy can lead to folate deficiency. Anti-convulsant-induced folate deficiency has been associated with megaloblastic anemia, cognitive decline, vascular diseases, cancer, psychiatric comorbidity, spontaneous abortion and teratogenesis. Thus, patients with epilepsy are a suitable population to investigate the association of AED treatment with folate serum levels in comparison with normal population. Method. This is comparative cross-sectional study focusing on the level and intake of folate in relation with AED (phenytoin, phenobarbital, carbamazepine, valproic acid) in epileptic patients in outpatient clinic of Neurology Cipto Mangunkusumo General Hospital and Indonesia Epilepsy Foundation, with comparison to normal population. Seventy five epileptic patients and seventy six healthy people were recruited with food recall interview and their serum folate were measured. Results. The mean folate serum of study group were 9.95 + 3.61 ng/mL and the mean folate serum of control group were 4.59 + 2.4 ng/mL (p=<0.001). The mean dietary folate of study group were 119.7 (28.4 ? 340) microgram and the mean dietary folate of control group 104.65 (38-510) microgram (p=0.095). Conclusion. The mean folate serum in study group were significant much more higher compare with the control group. As many as 2.7% of study group with significantly low folate serum level. There were no any significant association of dietary folate with folate serum classification of study group. , Background.. Antiepileptic drugs (AEDs) are frequently used in the treatment of epilepsy, psychiatric diseases, and pain syndromes. Studies have established that chronic anticonvulsant therapy can lead to folate deficiency. Anti-convulsant-induced folate deficiency has been associated with megaloblastic anemia, cognitive decline, vascular diseases, cancer, psychiatric comorbidity, spontaneous abortion and teratogenesis. Thus, patients with epilepsy are a suitable population to investigate the association of AED treatment with folate serum levels in comparison with normal population. Method. This is comparative cross-sectional study focusing on the level and intake of folate in relation with AED (phenytoin, phenobarbital, carbamazepine, valproic acid) in epileptic patients in outpatient clinic of Neurology Cipto Mangunkusumo General Hospital and Indonesia Epilepsy Foundation, with comparison to normal population. Seventy five epileptic patients and seventy six healthy people were recruited with food recall interview and their serum folate were measured. Results. The mean folate serum of study group were 9.95 + 3.61 ng/mL and the mean folate serum of control group were 4.59 + 2.4 ng/mL (p=<0.001). The mean dietary folate of study group were 119.7 (28.4 – 340) microgram and the mean dietary folate of control group 104.65 (38-510) microgram (p=0.095). Conclusion. The mean folate serum in study group were significant much more higher compare with the control group. As many as 2.7% of study group with significantly low folate serum level. There were no any significant association of dietary folate with folate serum classification of study group. ]"