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"ABSTRAK Latar belakang: Kolesistektomi merupakan tindakan abdomen tersering dan saat inikolesistektomi laparoskopi (KL) merupakan baku emas dan telah dilakukan pada 90% kasuskolesistitis simtomatik. Tujuan penelitian ini adalah untuk mengetahui hasil KL di RSCM,Jakarta. Metode: Penelitian retrospektif observasional ini menggunakan data dari departemen bedahdivisi digestif RSCM dari bulan Januari hingga Desember 2014. Partisipan penelitian iniadalah pria atau wanita yang berusia 23-66 tahun yang menjalani KL. Tindakan bedahdilakukan baik berupa perawatan 1 hari (one day care (ODC)) maupun elektif. Data yangdikaji adalah temuan preoperatif dan intraoperatif, durasi operasi, lama rawat inap, dan angkakonversi ke tindakan kolesistektomi terbuka (open). Kemudian kami menganalisis faktoryang mempengaruhi angka konversi. Hasil: Jumlah pasien yang masuk inklusi adalah 90 orang. Usia rata-rata 43,9 tahun (SE=1,26tahun) dengan jumlah pasien wanita 61 orang (67,8%). Median durasi operasi adalah 90±36,9menit dimana pasien yang konversi membutuhkan operasi lebih dari 2 jam lebih banyak(12% vs 1,5%), namun tidak bermakna secara statistik (p= 0,63). Median lama rawat inapadalah 9±27.2 hari dan meningkat bermakna pada kasus yag konversi (24±9 hari, p = 0.011).Median lama pre-operasi = 7±26,8 hari, dan pasca-operasi = 2±3.8 hari, dengan 13,3% pasiendilakukan endoscopic retrograde cholangio-pancreatography (ERCP) sebelum KL. Cederaduktus biliaris komunis (CBDK) ditemukan pada 3 kasus (3,33%). Konversi menjadilaparotomi dibutuhkan pada 4,44% kasus. Faktor yang mempengaruhi angka konversi hanyapada kasus adhesi (RR (95%IK) = 25,7 (2,4-273,5); p=0,007. Kesimpulan temuan: kolesistektomi laparoskopi menawarkan lama rawat inap yang lebihsingkat. Durasi operasi pendek dan prosedur ini standard, aman, dan efektif di institusi kami. ABSTRACT Background: Cholecystectomy is the most frequently performed abdominal operation andcurrently laparoscopic cholecystectomy (LC) is considered gold standard being performed in90% cases of symptomatic gallstones. The aim of the study was to determine results obtainedwith LC at our hospital, RSCM, Jakarta. Methods: This retrospective observational study was conducted in digestive divison insurgery department of RSCM using data from January to December 2014. The studyparticipants were patients of both gender aged 23?66 years undergoing LC. Surgery wasperformed either in one day care (ODC) or elective schedule. Demographic variables,preoperative and intraoperative findings, mean operation time, hospital stay, and conversionrate were evaluated. Factors influencing rate of conversion were also studied. Results: A total of 90 patients were included. Mean age was 43.9 years (SE=1.26 years) witha female 61 (67.8%). Median operative time was 90±36.9 minutes which converted casespatient needed to operate in more than 2 hours (12% vs 1.5%), but not statistically significant(p= 0.63). Median hospital stay was 9±27.2 days that significantly increased in convertedcases (24±9 days, p-value= 0.011). Median of pre-operation = 7±26.8 days, and postoperation= 2±3.8 days, with 13.3% patients underwent endoscopic retrograde cholangiopancreatography(ERCP). Common bile duct injury (CBDI) was found in 3 cases (3.33%).Conversion to laparotomy was required in 4.44% cases. Factors that influenced the rate ofconversion included was only adhesion (RR (95%CI) = 25.7 (2.4-273.5), p=0.007. Findings: Laparoscopic cholecystectomy offers shorter hospital stay. The operative time isshort and procedure is standard, safe and effective in our institution.;Background: Cholecystectomy is the most frequently performed abdominal operation andcurrently laparoscopic cholecystectomy (LC) is considered gold standard being performed in90% cases of symptomatic gallstones. The aim of the study was to determine results obtainedwith LC at our hospital, RSCM, Jakarta. Methods: This retrospective observational study was conducted in digestive divison insurgery department of RSCM using data from January to December 2014. The studyparticipants were patients of both gender aged 23?66 years undergoing LC. Surgery wasperformed either in one day care (ODC) or elective schedule. Demographic variables,preoperative and intraoperative findings, mean operation time, hospital stay, and conversionrate were evaluated. Factors influencing rate of conversion were also studied. Results: A total of 90 patients were included. Mean age was 43.9 years (SE=1.26 years) witha female 61 (67.8%). Median operative time was 90±36.9 minutes which converted casespatient needed to operate in more than 2 hours (12% vs 1.5%), but not statistically significant(p= 0.63). Median hospital stay was 9±27.2 days that significantly increased in convertedcases (24±9 days, p-value= 0.011). Median of pre-operation = 7±26.8 days, and postoperation= 2±3.8 days, with 13.3% patients underwent endoscopic retrograde cholangiopancreatography(ERCP). Common bile duct injury (CBDI) was found in 3 cases (3.33%).Conversion to laparotomy was required in 4.44% cases. Factors that influenced the rate ofconversion included was only adhesion (RR (95%CI) = 25.7 (2.4-273.5), p=0.007. Findings: Laparoscopic cholecystectomy offers shorter hospital stay. The operative time isshort and procedure is standard, safe and effective in our institution.;Background: Cholecystectomy is the most frequently performed abdominal operation andcurrently laparoscopic cholecystectomy (LC) is considered gold standard being performed in90% cases of symptomatic gallstones. The aim of the study was to determine results obtainedwith LC at our hospital, RSCM, Jakarta. Methods: This retrospective observational study was conducted in digestive divison insurgery department of RSCM using data from January to December 2014. The studyparticipants were patients of both gender aged 23?66 years undergoing LC. Surgery wasperformed either in one day care (ODC) or elective schedule. Demographic variables,preoperative and intraoperative findings, mean operation time, hospital stay, and conversionrate were evaluated. Factors influencing rate of conversion were also studied. Results: A total of 90 patients were included. Mean age was 43.9 years (SE=1.26 years) witha female 61 (67.8%). Median operative time was 90±36.9 minutes which converted casespatient needed to operate in more than 2 hours (12% vs 1.5%), but not statistically significant(p= 0.63). Median hospital stay was 9±27.2 days that significantly increased in convertedcases (24±9 days, p-value= 0.011). Median of pre-operation = 7±26.8 days, and postoperation= 2±3.8 days, with 13.3% patients underwent endoscopic retrograde cholangiopancreatography(ERCP). Common bile duct injury (CBDI) was found in 3 cases (3.33%).Conversion to laparotomy was required in 4.44% cases. Factors that influenced the rate ofconversion included was only adhesion (RR (95%CI) = 25.7 (2.4-273.5), p=0.007. Findings: Laparoscopic cholecystectomy offers shorter hospital stay. The operative time isshort and procedure is standard, safe and effective in our institution.;Background: Cholecystectomy is the most frequently performed abdominal operation andcurrently laparoscopic cholecystectomy (LC) is considered gold standard being performed in90% cases of symptomatic gallstones. The aim of the study was to determine results obtainedwith LC at our hospital, RSCM, Jakarta. Methods: This retrospective observational study was conducted in digestive divison insurgery department of RSCM using data from January to December 2014. The studyparticipants were patients of both gender aged 23?66 years undergoing LC. Surgery wasperformed either in one day care (ODC) or elective schedule. Demographic variables,preoperative and intraoperative findings, mean operation time, hospital stay, and conversionrate were evaluated. Factors influencing rate of conversion were also studied. Results: A total of 90 patients were included. Mean age was 43.9 years (SE=1.26 years) witha female 61 (67.8%). Median operative time was 90±36.9 minutes which converted casespatient needed to operate in more than 2 hours (12% vs 1.5%), but not statistically significant(p= 0.63). Median hospital stay was 9±27.2 days that significantly increased in convertedcases (24±9 days, p-value= 0.011). Median of pre-operation = 7±26.8 days, and postoperation= 2±3.8 days, with 13.3% patients underwent endoscopic retrograde cholangiopancreatography(ERCP). Common bile duct injury (CBDI) was found in 3 cases (3.33%).Conversion to laparotomy was required in 4.44% cases. Factors that influenced the rate ofconversion included was only adhesion (RR (95%CI) = 25.7 (2.4-273.5), p=0.007. Findings: Laparoscopic cholecystectomy offers shorter hospital stay. The operative time isshort and procedure is standard, safe and effective in our institution.;Background: Cholecystectomy is the most frequently performed abdominal operation andcurrently laparoscopic cholecystectomy (LC) is considered gold standard being performed in90% cases of symptomatic gallstones. The aim of the study was to determine results obtainedwith LC at our hospital, RSCM, Jakarta. Methods: This retrospective observational study was conducted in digestive divison insurgery department of RSCM using data from January to December 2014. The studyparticipants were patients of both gender aged 23?66 years undergoing LC. Surgery wasperformed either in one day care (ODC) or elective schedule. Demographic variables,preoperative and intraoperative findings, mean operation time, hospital stay, and conversionrate were evaluated. Factors influencing rate of conversion were also studied. Results: A total of 90 patients were included. Mean age was 43.9 years (SE=1.26 years) witha female 61 (67.8%). Median operative time was 90±36.9 minutes which converted casespatient needed to operate in more than 2 hours (12% vs 1.5%), but not statistically significant(p= 0.63). Median hospital stay was 9±27.2 days that significantly increased in convertedcases (24±9 days, p-value= 0.011). Median of pre-operation = 7±26.8 days, and postoperation= 2±3.8 days, with 13.3% patients underwent endoscopic retrograde cholangiopancreatography(ERCP). Common bile duct injury (CBDI) was found in 3 cases (3.33%).Conversion to laparotomy was required in 4.44% cases. Factors that influenced the rate ofconversion included was only adhesion (RR (95%CI) = 25.7 (2.4-273.5), p=0.007. Findings: Laparoscopic cholecystectomy offers shorter hospital stay. The operative time isshort and procedure is standard, safe and effective in our institution."

"Komplikasi dan mortalitas pada pasien karsinoma rektum yang menjalani operasi masih cukup tinggi. Analisa faktor-faktor risiko dan klasifikasi komplikasi paska operasi yang terjadi diharapkan dapat menurunkan angka komplikasi yang dapat terjadi. Pada penelitian ini kami menggunakan suatu sistem klasifikasi komplikasi Clavien-Dindo, menstrafikasi komplikasi menjadi lima grade dan melakukan analisa faktor-faktor resiko yang mempengaruhi timbulnya komplikasi paska operasi secara signifikan. Penelitian ini merupakan suatu studi kohort retrospektif yang melibatkan 65 pasien yang menjalani operasi karsinoma rektum di RSCM selama periode Januari 2012 dan Desember 2015. Review rekam medis pasien karsinoma rektum pada semua stadium yang menjalani pembedahan dan variabel lainnya termasuk jenis kelamin, body mass index BMI , riwayat tranfusi preoperatif, jenis pembedahan, setting operasi dan tujuan operasi. Hasil penelitian menunjukkan 55,4 grade I, 15.4 grade II, 3,1 grade IIIA, 6,2 grade IIIB, 13,8 grade IV, dan grade V sebesar 6,2 . Transfusi darah preoperatif menunjukkan adanya hubungan yang bermakna terhadap risiko komplikasi pascabedah karsinoma rektum P = 0,04 . Studi ini menunjukkan bahwa faktor risiko yang berpengaruh pada komplikasi pascaoperasi kanker rektum adalah transfusi preoperasi.

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Postoperative morbidity and mortality is a burden in patients with rectal cancer. Analyzing as well as classifying postoperative complication into a universal and standardized method could minimize this burden. Using Clavien Dindo postoperative complication grading system, we stratify complications into five grades and analyze the contributed risk factors in order to identify significant risk factors in reducing patient morbidity and mortality. This retrospective cohort study involved 65 patients which surgery was done between January 2012 and December 2015. It reviewed the medical records of patients diagnosed with rectal carcinoma at any stage and obtain another variable including sex, age, body mass index BMI , preoperative transfusion history, procedure, intention, and approach of the surgery. The result shows 55,4 of the patient was grade I, 15.4 grade II, 3,1 grade IIIA, 6,2 grade IIIB, 13,8 grade IV, and grade V was 6,2 of all patients. Among all of the risks, preoperative transfusion history was the only one statistically significant risk that affect severity of grade P 0,04 ."

"Latar Belakang. Pemberian kemoterapi oxaliplatin sebagai salah satu modalitas terapi kanker kolorektal telah terbukti memperbaiki angka kesembuhan, ketahanan hidup maupun masa bebas penyakit dan kualitas hidup penderita. Namun, juga memberikan berbagai efek samping toksisitas hematologi anemia, leukopenia, dan trombositopenia yang paling sering ditemukan. Metode. Penelitian ini merupakan penelitian observasional dengan menggunakan rancangan hysterikal kohort. Penelitian dilakukan di Departemen Bedah Fakultas Kedokteran Universitas Indonesia Divisi Bedah Digestif RSCM, periode Januari 2016 - Desember 2016. Populasi sasaran adalah 65 pasien kanker kolorektal yang mendapat kemoterapi oxaliplatin adjuvan. Hasil. Usia pasien kanker kolorekta berkisar antara 18 tahun sampai dengan 73 tahun rata-rata 50,8 tahun, perbandingan pria 32 49,2 dan wanita33 50,8. dari 65 pasien kanker kolorektal distribusi lokasi tumor terbanyak pada rektum 39 60, sigmoid 11 16,9, kolon desenden 7 10,8, kolon tranversum 5 7,7, kolon asenden 2 3,1, dan pada caecum 1 1,5. Stadium terbanyak adalah stadium II dan tindakan pembedahan berupa Low Anterior Resction atau Anterior Perineal Resection. Terdapat penurunan rerata kadar hemoglobin yang bermakna dengan p

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Background. The administration of oxaliplatin chemotherapy as one of the therapeutic modalities of colorectal cancer has been shown to improve the rate of cure, survival and disease free and quality of life of patients. However, it also provides the most common side effects of hematologic toxicity anemia, leukopenia, and thrombocytopenia.

Methods. This research is an observational using hysterical cohort design. It was conducted in Department of Surgery Faculty of Medicine, University of Indonesia Division of Digestive Surgery RSCM, periode January 2016 December 2016. The target population is 65 patients of colorectal cancer receiving adjuvant oxaliplatin chemotherapy.

Results The age of colorectal cancer patients ranged from 18 to 73 years mean 50.8 years, male 32 49.2 and female 33 50.8. 65 patients of colorectal cancer distributed the most tumor sites in the rectum 39 60, sigmoid 11 16.9, descending colon 7 10.8, tranversum colon 5 7.7, ascending colon 2 3.1, and at caecum 1 1.5. Most stages are stage II and the operate type of Low Anterior Resction or Anterior Perineal Resection. There was a significant decrease in mean hemoglobin level with p "

"ABSTRAKObjektif: Pembedahan merupakan tatalaksana paliatif utama dari kanker periampular stadium lanjut, namun hal tersebut memiliki angka komplikasi postoperatif, rekurensi penyakit, dan mortalitas yang tinggi. Objektif dari penelitian ini yaitu untuk mengetahui faktor prognostik dan sintasan penyakit selama 1 tahun dari kanker periampular stadium lanjut pada Rumah Sakit Cipto Mangunkusumo. Metode: Penelitian ini merupakan uji analisis sintas dengan desain kohort retrospektif. Data dikumpulkan dari pendaftaran per bulan dari Divisi Bedah Digestif dan rekam medis dari Rumah Sakit Cipto Mangunkusumo dari Januari 2015 hingga Desember 2017. Sintasan penyakit satu tahun dianalisis dengan metode Kaplan-Meier. Dilakukan analisis bivariat dan multivariat dari masing-masing variabel pada sintasan satu tahun pasien. Hasil: Sintasan penyakit selama 1 tahun dari pasien post-double bypass yaitu 19% dengan median (minimal-maksimal) sintasan yaitu 159 (2-365) hari. Berdasarkan perbandingan antarkelompok sintasan pasien, hemoglobin (p=0,013) dan klasifikasi ASA (p=0,001) memiliki estimasi sintasan yang bermakna secara statistik. Pada analisis multivariat, jenis kelamin (p=0,250, HR=3,910) dan nilai laboratorium preoperatif (albumin (p=0,350, HR=0,400), aspartat aminotransferase (AST) (p=0,13, HR=5,110) dan alanin aminotransferase (ALT) (p=0,280, HR=0,05)) berhubungan dengan sintasan. Kesimpulan: Sintasan selama 1 tahun pada pasien post-double bypass pada Rumah Sakit Cipto Mangunkusumo rendah. Laju mortalitas satu bulan yang rendah mengindikasikan bahwa double bypass merupakan prosedur yang aman. Faktor prognostik yang berhubungan dengan sintasan yang rendah yaitu jenis kelamin perempuan dan nilai laboratorium preoperatif (albumin, AST, ALT).

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ABSTRACTObjective: Surgery is the main palliative treatment of advanced periampullary cancer, however it has high number of post-operative complication, disease recurrence and mortality. The objective of the current study was to examine prognostic factors and one year survival rate of advanced stage periampullary cancer in Cipto Mangunkusumo Hospital. Methods: This is a survival analysis test study with retrospective cohort design. Data were collected from monthly registration of Digestive Surgery Division and medical records from Cipto Mangunkusumo Hospital from January 2015 until December 2017. One year survival rate were analyzed with Kaplan-Meier method. Bivariate and multivariate analysis of each variable on one year survival of the patient were done. Result: One year survival rate of the post-double bypass patients is 19% with median (min-max) survival 159 (2-365) days. From the comparison of survival rate based patients grouping, hemoglobin (p=0.013) and ASA classification (p=0.001) have significant survival estimation statistically. In multivariate analysis, gender (p=0.250, HR=3.910) and preoperative laboratory values (albumin (p=0.350, HR=0.400), aspartate aminotransferase (AST) (p=0.13, HR=5.110) and alanine aminotransferase (ALT) (p=0.280, HR=0.05)) are associated with survival rate. Conclusion: One year survival rate of post double bypass patients in Cipto Mangunkusumo hospital is low. Low one month mortality rate indicates double bypass is a safe procedure. Prognostic factors that associated with lower survival are woman gender and preoperative laboratory value (albumin, AST, ALT)."

"Latar Belakang: Protokol ERAS (Enhanced Recovery After Surgery) adalah sebuah strategi perioperatif berbasis bukti, yang terbukti dapat menurukan lama perawatan pascaoperas dan angka komplikasi pada kasus pembedahan di bidang kolorektal. Penerapan ERAS terdiri atas 15 komponen, namum evaluasi penerapan komponen ini bila dihubungkan dengan luaran masih belum jelas. Metode: Studi retrospektif dilakukan kepada 63 pasien yang telah menjalani operasi elektif kolorektal berbasis protokol ERAS dari Januari 2015 hingga Desember 2017 di Rumah Sakit Cipto Mangunkusumo. Karakteristik pasien, demografi, termuan klinis dan lama perawatan dikumpulkan dari rekam medis. Hubungan antara jumlah komponen ERAS yang diterapkan dikaitkan dengan lama rawat dianalisis. Hasil: Semua pasien diterapkan jumlah komponen ERAS hingga maksimal 11 komponen dari total 15 komponen. Usia rata-rata pasien adalah 53 tahun; 46% pasien laki-laki, dan 54% perempuan. Tidak ditemukan angka mortalitas. Angka morbiditas sebesar 7,9%, disebabkan oleh infeksi luka operasi 1,6%, pneumonia 1,6%, dan retensi urin 4,8%. Lokasi tersering dari tumor kolorektal adalah sigmoid (47%). Prosedur operasi yang paling sering dikerjakan adalah tutup kolostomi (25,4%). Terdapat hubungan yang bermakna antara jumlah penerapan komponen protokol ERAS dan lama perawatan pasca operasi. (p<0.01, r = 0,568). Kesimpulan: Semakin banyak jumlah komponen ERAS yang diterapkan ke satu pasien, semakin singkat lama perawatan pasca operasi. Kata kunci: Enhanced Recovery After Surgery, Evaluasi, Kolorektal 

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Background. The enhanced recovery after surgery (ERAS) protocol in colorectal surgery has proven to be effective in reducing postoperative length of stay and perioperative complications rates in hospital. At Cipto Mangunkusumo Hospital, ERAS protocol for colorectal surgery has been known since 2015. However, there has never been a program evaluation of the ERAS components that has been applied in relation to outcomes.

Method. Sixty-three colorectal patients who underwent surgical procedures from 2015 to 2017 were retrospectively evaluated for complete implementation of ERAS protocol. Complete implementation is defined as the ability to accomplish 15 ERAS components. Demographic, clinical data, and length of stay (LOS) were also collected from medical records.

Results. Up to 11 out of 15 ERAS components were implemented to 63 patients. The proportion of male was 46% compare to female was 54%. The average age was 53 years old; mortality rates 0%, morbidity rates 7,9% (surgical site infection 1,6%; pneumonia 1,6%; and urinary retention 4,8%). The most common location of tumor and procedure were sigmoid (47,6%), colostomy closure (25,4%). It is found that there is a relationship between the total number of components that are corresponding to ERAS protocol per subject and the average length of stay. The more number of ERAS components that are fulfilled per subject, the shorter the average length of subject visits became (p<0,01, r = 0,568).

Conclusion. Cipto Mangunkusumo Hospital does not yet have an ERAS protocol for colorectal surgery, but has implemented 11 ERAS components out of a total of 15 ERAS components from Toronto as a perioperative management. The greater number of ERAS components that are applied to one subject, the shorter the postoperative care.

Keyword: Colorectal, enhanced recovery after surgery, evaluation"

"ABSTRAKPenelitian ini dilakukan untuk meneliti apakah stadium lanjut pada kanker kolorektal berdasarkan Union for International Cancer Control Staging System, mempunyai pengaruh terhadap tingginya tingkat kebocoran anastomosis usus setelah operasi kanker kolorektal.Metode : Penelitian ini merupakan penelitian studi kohort retrospektif yang dilakukan pada 398 pasien kanker kolorektal yang datang ke RSUPN Cipto Mangunkusumo, Jakarta, Indonesia dari bulan Januari 2013 sampai Desember 2015, dari jumlah tersebut, terdapat 156 kasus yang menjalani tatalaksana pembedahan berupa operasi reseksi dengan anastomosis primer, ynag terdiri dari 110 pasien 70,5 kasus stadium II-III dan 46 pasien 29,5 kasus stadium IV. Tidak ditemukan pasien dengan stadium I yang datang ke RSCM. Data-data lain yang diketahui memiliki faktor risiko terhadap kebocoran anastomosis seperti jenis kelamin laki-laki, operasi elektif atau emergensi dan pengunaan ileostomi proteksi, dibandingkan antara kedua grup tersebut. Tidak ada perbedaan yang signifikan diantara kedua grup.Hasil penelitian : Tidak ada perbedaan yang signifikan pada jenis kelamin P = 0,755 , operasi emegensi atau elektif P = 0,089 , penggunaan ileostomy proteksi P = 1,00 dan stadium lanjut kanker kolorektal P = 0,084 dengan kebocoran anastomosis.Kesimpulan : Dari hasil penelitian didapatkan bahwa tidak ada hubungan yang bermakna antara stadium lanjut kanker kolorektal dengan kebocoran anastomosis pada operasi kanker kolorektal

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ABSTRACTThe objective of this study was to investigate whether advanced stages of colorectal cancer Union for international Cancer Control staging system correlates with higher risk of anastomotic leakage after colorectal cancer surgery.Method A retrospective cohort study was conducted on 398 colorectal cancer cases that was admitted at National Referral Hospital, Cipto Mangunkusumo, Jakarta, Indonesia from January 2013 until December 2015. Among these patients, 156 cases underwent surgical resections with primary anastomosis and consisted of 110 70,5 cases of stage II III and 46 29,5 cases of stage IV. No patients with stage I were found at the hospital. Demographic data and known risk factors for anastomotic leak were also recorded and compared between these groups, including male gender, elective or emergency surgery and use of protective ileostomy. There were no differences in these factors between the two groups.Results there were no significant differences with regards to gender P 0,755 , the type of operative setting elective or emergency with P 0,089 , use of protective ileostomy P 1,00 and advanced stages of colorectal cancer P 0,084 with anastomotic leak rate.Conclusion these results suggest there was no correlation between different colorectal cancer stages with anastomotic leak rate in colorectal surgery in National Referral Hospital, Cipto Mangunkusumo, Jakarta, Indonesia"

"ABSTRAK Pembedahan terbuka kolorektal mempunyai morbiditas yang tinggi. Laparoskopi kolorektal pertama kali diperkenalkan pada tahun 1991 dengan hasil morbiditas pascabedah yang rendah. Penelitian ini mengambil total sampel subjek kanker kolorektal yang menjalani pembedahan laparoskopi pada tahun 2010 hingga 2015. Data ditabulasi dan dianalsis untuk mendapatkan hasil jangka pendek dan kesintasan lima tahun. Didapatkan 65 data dengan 21 kasus kolon 32,3 dan 44 kasus rektum 67,7 ; 34 pria 52,3 31 wanita 47,7 dengan rata ndash;rata usia 57,17 tahun SD 13.380 . Pada kelompok kolon didapatkan rata ndash;rata durasi bedah 216,75 menit SD 65,94 dan kehilangan darah 159,75 mL SD 125,47 . Median VAS adalah empat; diet, mobilisasi dan lama rawat pascabedah didapatkan pada dua, empat dan tujuh hari. Kesintasan lima tahun pasien didapatkan 83 . Tidak ada komplikasi, pembedahan ulang dan infeksi luka operasi ILO pada kelompok ini. Pada kelompok rektum rata ndash;rata durasi bedah adalah 305,97 min SD 94,23 dan perdarahan intra operasi 150 mL SD 50 . Median VAS pascabedah tiga, diet dan mobilisasi pascabedah dua hari dan empat hari. Lama rawat pascabedah delapan hari. Kesintasan lima tahun adalah 58,5 . Morbiditas pascabedah lebih rendah dengan pembedahan laparoskopi dengan hasil kesintasan keseluruhan yang tidak berbeda dengan kesintasan pasien kanker kolorektal yang ditangani sebelumnya. ABSTRACT Conventional colorectal cancer surgery is often associated with high post operative moribidities. Laparoscopic colorectal surgery has reduced post operative morbidities with same survival outcomes of open surgery. Retrospective data of laparoscopic colorectal cancer surgery from 2010 to 2015 were collected, tabulated and analyzed to get early results and five years survival rate. There were 65 data, 21 colon cancer 32.3 and 44 rectal cancer 67.7 . Higher incidence of male patients n 34, 52.3 than female n 31, 47.7 with mean age of 57,17 13.38 years. Length of operation for colon group was 216.75 SD 65.94 mins with intra operative blood loss 159.75 SD 125.47 mL and post operative pain, on visual analog score VAS , was 4 2 5 . Post operative diet, mobilization and length of stay were 2 1 3 days, 4 2 7 days and 7 4 12 days respectively. The five years survival rate was 83 . In rectal group, length of operation was 305,97 SD 94,23 mins with intra operative blood loss 150 SD 50 mL. Post operative VAS, diet, mobilization and length of stay were 3 2 5 , 2 1 4 days, 4 2 22 days and 8 5 36 days respectively. Five years survival rate was 58.5 . Post operative morbidities in colorectal cancer decreases with laparoscopic resection with satisfactory overall survival rate."

"Latar Belakang: Pankreatikoduodenektomi (PD) merupakan prosedur pilihan pada keganasan periampula yang dapat direseksi. Namun, angka kematian pasca operasi untuk PD relatif tinggi. Prediksi kematian dengan sistem penilaian membantu memilih pasien yang memenuhi syarat operasi untuk meminimalkan risiko kematian. Studi ini membandingkan empat sistem penilaian kematian pasca prosedur PD, termasuk skor prognostik Naples (SPN), WHipple-ABACUS (WA), skor Pitt yang dimodifikasi (MSP), dan skor Pitt pada populasi Indonesia.Metode: Kami mengidentifikasi pasien yang menjalani PD karena keganasan periampula di Rumah Sakit Umum Nasional Dr. Cipto Mangunkusumo antara Januari 2010 dan Januari 2022. Kami menilai akurasi, cut-off, sensitivitas, spesifisitas, negative predictive value, positive predictive value, dan area di bawah kurva (AUC). Nilai AUC dari masing-masing sistem penilaian dibandingkan dengan menggunakan uji De-Long. Kami juga menganalisis prediktor kematian.Hasil: Dari 116 pasien yang memenuhi kriteria, angka kematian 29,3%. Rerata usia tahun 51,63 ± 10,22 terdiri dari 75,9% kelompok <60 tahun dan 24,1% 60 tahun, dengan 46,6% laki-laki dan 53,4% perempuan. AUC dari yang tertinggi hingga terendah adalah Pitt Score 0,662 (p 0,006), MPS 0,631 (p 0,027), WA 0,539 (p 0,505), dan SPN 0,495 (p 0,932) dengan tingkat akurasi masing-masing skor adalah skor Pitt 63,79%, MSP 65,52%, WA 50,00%, dan SPN 57,76%.Kesimpulan: Skor Pitt dan MSP memiliki akurasi tertinggi dari semua sistem penilaian dalam penelitian ini. MSP memiliki keuntungan yaitu komponen yang lebih sedikit, sehingga mudah untuk diimplementasikan. MSP dapat menggantikan peran Skor Pitt dalam memprediksi mortalitas pasca-prosedur pankreatikoduodenektomi di Indonesia.

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Background: Pancreaticoduodenectomy (PD) is the procedure of choice in resectable periampullary malignancies. However, the postoperative mortality rate for PD is relatively high. Prediction of mortality with a scoring system helps select patients eligible for surgery to minimize mortality risk. The study compared four post-procedural mortality scoring systems for PD, including Naples prognostic score (NPS), WHipple-ABACUS (WA), modified Pitt score (MPS), and Pitt score in Indonesian population.

Methods: We identified patients who underwent PD due to periampullary malignancy at Dr. Cipto Mangunkusumo National General Hospital between January 2010 and January 2022. We assessed accuracy, cut-off, sensitivity, specificity, negative predictive value, positive predictive value, and area under the curve (AUC). The AUC values of each scoring system were compared using De-Long test. We also analyzed predictors of mortality.

Results: Of the 116 patients who met the criteria, the mortality rate was 29.3%. Mean age years 51.63 ± 10.22 consist of 75.9% group <60 years and 24.1% ≥60 years, with 46.6% male and 53.4% female. The AUC from highest to lowest were Pitt Score 0.662 (p 0.006), MPS 0.631 (p 0.027), WA 0.539 (p 0.505), and NPS 0.495 (p 0.932) with the level of accuracy of each score were Pitt Score 63.79%, MPS 65.52%, WA 50.00%, and NPS 57.76%.

Conclusions: The Pitt and MPS scores have the highest accuracy of all the scoring systems in this study. MPS has the advantage of having fewer components, making it easy to implement. MPS can replace the role of the Pitt Score in predicting post-procedure PD mortality in Indonesia."

"Latar Belakang: Infeksi daerah operasi (IDO) meliputi 20% dari kejadian hospital acquired infection pada pembedahan yang dilatari berbagai macam faktor, termasuk faktor internal (usia, jenis kelamin, penyakit bawaan) maupun faktor eksternal (pola makan, merokok, pengobatan yang dijalani). Selain itu, pembedahan sendiri juga membawa faktor-faktor risiko yang bisa menyebabkan IDO, seperti jenis pembedahan, lama pembedahan, dan sebagainya. Diperlukan sebuah analisis yang dilihat dari faktor-faktor tersebut dan bagaimana hubungannya terhadap kejadian IDO. Metode: Penelitian ini menggunakan desain kohort retrospektif dengan data rekam medis pasien Divisi Bedah Digestif, Departemen Bedah RSCM tahun 2012 hingga 2016. Kriteria inklusi, yakni semua pasien RSCM yang ditangani staf divisi Bedah Digestif FKUI RSCM selama periode 2012-2016 dengan rekam medik yang tercatat baik, lengkap, dan datanya tersedia dengan ekslusi, jika data rekam medis yang dibutuhkan tidak lengkap. Sampel diambil dengan cara random sampling meliputi semua pasien yang memenuhi kriteria inklusi dan tidak mengenai kriteria eksklusi, didapatkan sampel minimal 58 per kelompok. Data diambil dan dimasukkan ke dalam tabel Microsoft Excel dan kemudian dianalisis secara univariat, bivariat, dan multivariat. Hasil: Pada uji bivariat dan multivariat, didapatkan bahwa “Derajat Kontaminasi” adalah faktor yang berpengaruh secara signifikan terhadap kejadian IDO. Kesimpulan: Terdapat hubungan yang kuat antara faktor risiko intrabedah dengan IDO di RSCM. Derajat kontaminasi adalah faktor risiko yang signifikan terhadap IDO. Penelitian selanjutnya sebaiknya memakai metode kohort prospektif, dengan sampel pasien yang diikuti sejak admisi, tidak ada masalah nutrisi untuk pasien lanjut usia, dengan lama rawat pra-bedah di bawah 7 hari, dan ada perluasan jangkauan faktor risiko yang dianalisa.

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Background: Surgical site infection (SSI) after gastrointestinal surgery can affect mortality and morbidity of the patients. Risk factors are needed to prevent and decrease number of SSI. This study investigated the pre-operative and intra-operative risk factors of gastrointestinal surgeries and incidence of SSI.

Methods: A retrospective audit analysis of age, nutritional status, pre-operative length of stay, length of surgery, type of surgery, degree of contamination in adult gastrointestinal surgery patients at Cipto Mangunkusumo General Hospital was conducted from the medical records from 2012 to 2016. Outcomes consisted of incidence and potential univariate risk factors were determined to investigate the independent associated factors using multivariate logistic regression.

Results: The incidence of SSI in four years is 3.4% among 4,357 gastrointestinal surgeries with 86.4% of surgical site infection appears in contaminated wound operations. Our study included 116 subjects. From univariate analysis between SSI as dependent factors and the the risks factors, age (p=0,2), pre operative length of stay (p=0,06), length of surgery (p=0,1), and degree of contamination (p=0,003) have correlative association with SSI. The risk factor with surgical site infection is surgical wound contamination (OR=1.233, p=0.011) and independent from other risk factors.

Conclusions: From pre operative and intra operative risk factors there are four factors which have correlation with SSI, there are age, pre operative length of stay, length of surgery, and degree of contamination. Degree of contamination is the significant risk factors for SSI."

"Latar Belakang: Penanganan batu empedu dapat dilakukan melalui intervensi bedah atau non-bedah. Untuk penanganan bedah, kolesistektomi dapat dilakukan dengan teknik terbuka maupun laparoskopik. Tindakan ERCP yang diikuti oleh kolesistektomi dianggap sebagai modalitas terapi terbaik saat ini. Teknik ini bisa dilakukan sebelum tindakan kolesistektomi laparoskopik atau dilakukan secara bersamaan. Saat ini masih belum disepakati alur strategi yang terbaik, mengenai interval waktu untuk melakukan tindakan kolesistektomi laparoskopik pascaERCP. Metode: Deskriptif analitik dengan desain studi potong-lintang (cross-sectional study) dengan mengambil data rekam medis subjek pada 2 rumah sakit di Jakarta. Tatalaksana interval waktu tindakan kolesistektomi laparoskopik pascaERCP diketahui melalui telusur rekam medis. Hasil: Pada penelitian ini didapatkan lebih banyak subjek yang dilakukan tindakan operasi lebih dari 72 jam dibandingkan dengan kurang dari sama dengan 72 jam pascaERCP (27 subjek (56,2%) dibandingkan 21 subjek (43,8%). Total sampel pada penelitian ini adalah 48 subjek, melebihi jumlah sampel minimal yaitu 20 subjek. Pankreatitis terjadi pada 7 subjek (33%) pada kelompok kurang dari sama dengan 72 jam dan pada 7 subjek (26%) pada kelompok lebih dari 72 jam. Berdasarkan uji Chi-square, tidak ditemukan hubungan yang bermakna antara komplikasi pankreatitis dengan durasi kolesistektomi laparoskopik pascaERCP (p = 0,75). Kesimpulan: Tidak didapatkan perbedaan yang bermakna antara kelompok interval laparoskopik kolesistektomi awal (kurang dari sama dengan 72 jam) dan lambat (lebih dari 72 jam) pascaERCP dengan terjadinya komplikasi pascaERCP berupa pankreatitis. Tidak didapatkan perbedaan bermakna antara kelompok interval laparoskopik kolesistektomi awal (kurang dari sama dengan 72 jam) dan lambat (lebih dari 72 jam) pascaERCP dengan lama rawat pasien.

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Background: Gallstones can be managed through surgical or non-surgical intervention. Cholecystectomy can be performed with open or laparoscopic techniques. Endoscopic retrograde cholangiopancreatography followed by cholecystectomy is considered the best treatment modality at this time. This technique can be performed before laparoscopic cholecystectomy or done simultaneously. At present the best strategy path has not been agreed upon, regarding the time interval to perform post ERCP laparoscopic cholecystectomy.

Methods: Analytical descriptive with cross-sectional study design by taking the medical record from two hospitals in Jakarta. The timing of Post- laparoscopic cholecystectomy post ERCP time interval is obtained through medical record search.

Result: More subjects were treated with surgery after 72 hours compared to before72 hours post-ERCP (27 subjects (56.2%) compared to 21 subjects (43.8%). The total sample in this study was 48 subject, exceeding the minimum sample size of 20 subjects. Pancreatitis occurred in 7 subjects (33%) in the group before 72 hours and in 7 subjects (26%) in the group after 72 hours post ERCP. Based on the Chi-square test, there is no significant association between pancreatitis complications and the duration of post-CP laparoscopic cholecystectomy (p = 0.75).

Conclusion: There is no significant difference between the early laparoscopic cholecystectomy group (before 72 hours) and the late laparoscopic cholecystectomy group (less 72 hours) post-ERCP with the occurrence of complications post-ERCP determined as pancreatitis. There is no significant differences in the length of stay of the patient between the early laparoscopic cholecystectomy group (before 72 hours) and the late laparoscopic cholecystectomy group (less 72 hours) post-ERCP."