Ditemukan 5 dokumen yang sesuai dengan query
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Tujuan Penyesuaian dosis dan pemilihan jenis obat penting dilakukan dalam keadaan gangguan fungsi ginjal. Penelitian observasional ini bertujuan untuk mengetahui ketepatan penyesuaian dosis dan ketepatan pemilihan obat pada pasien di ruang rawat inap Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Indonesia/Rumah Sakit Dr. Cipto Mangunkusumo, Jakarta.
Metode Pasien usia 18 tahun atau lebih dengan bersihan kreatinin <60 mL/menit berdasarkan rumus Cockroft-Gault diikutkan dalam penelitian ini. Obat yang dinilai adalah obat yang ekskresinya terutama melalui ginjal dan ...
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Jakarta: Fakultas Kedokteran Universitas Indonesia, 2009
AJ-Pdf
Artikel Jurnal Universitas Indonesia Library
Anggi Gayatri
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ABSTRACT
Background: DLBS1033 is a bioactive protein fraction extracted from Lumbricus rubellus, with fibrinogenolytic, fibrinolytic and anti-aggregation activities reported in an in vitro study. Plasma half-life is an important parameter to calculate its dose. This study was conducted to evaluate the biological half-life of DLBS1033 by measuring serial plasmin-antiplasmin (PAP) complex. PAP complex is a stable and inactive compound as a result of fibrinolysis process. Methods: this was an open-label clinical trial in healthy adult subjects. ...
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Jakarta: University of Indonesia. Faculty of Medicine, 2018
610 UI-IJIM 50:3 (2018)
Artikel Jurnal Universitas Indonesia Library
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Background: the use of statin to lower blood cholesterol is often associated with bothersome adverse effects such as myopathy and liver dysfunction. NC120 is herbal lipid lowering drug containing red yeast rice (RYR) extract, guggulipid, and chromium picolinate, and expected to have better safety profile. The aim of this study was to evaluate the efficacy and safety profiles of NC120 in lowering blood lipid.
Methods: this was a double blind randomized clinical trial comparing NC120 ...
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Jakarta: Faculty of Medicine University of Indonesia, 2019
610 UI-IJIM 51:1 (2019)
Artikel Jurnal Universitas Indonesia Library
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Background: sarcopenia contributes to the development of frailty syndrome. Frailty syndrome is potentially improved by modifying insulin resistance, inflammation, and myostatin level. This study is aimed to investigate the effect of metformin on handgrip strength, gait speed, myostatin serum level, and health related quality of life (HR-QoL) among non diabetic pre frail elderly patients.
Methods: a double blind randomized controlled trial study was conducted on non-diabetic elderly outpatients aged >60 years with pre frail status based ...
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Jakarta: University of Indonesia. Faculty of Medicine, 2017
616 UI-IJIM 49: 2 (2017)
Artikel Jurnal Universitas Indonesia Library
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Background: HIV infection in HCV-infected patients accelerates disease progression and reduces the success rate of Peg-IFN/RBV treatment. HCV mutation in NS5A-ISDR/PKR-BD region improved the outcome in HCV monoinfection treated with Peg-IFN/RBV. SNP-IL28B polymorphism is predicted to have an effect on HCV quasispecies evolution. However, the role of NS5A mutation and SNP IL-28B in HIV-HCV coinfection is still unclear. The aim of the study is to determine the role of HCV NS5A-ISDR/PKR-BD mutation and SNP IL-28 ...
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Depok: Universitas Indonesia, 2019
610 UI-IJIM 51:2 (2019)
Artikel Jurnal Universitas Indonesia Library
