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Ditemukan 38 dokumen yang sesuai dengan query
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Arum Gunarsih
"[ABSTRAK
Latar belakang. Sepsis neonatorum awitan dini (SNAD) adalah sindrom klinis
akibat respon sistemik terhadap infeksi pada awal kehidupan. Diagnosis SNAD
seringkali sulit karena gejala klinisnya tidak spesifik.
Tujuan. Mengetahui sensitivitas dan spesifisitas biakan usap telinga dalam
diagnosis SNAD.
Metode. Subjek penelitian adalah neonatus yang lahir di RSCM Jakarta dan RSU
Tangerang Selatan dengan diagnosis SNAD. Dilakukan pengambilan biakan dari
usapan telinga dan darah bayi.
Hasil. Diantara 50 subjek, terdapat 2 neonatus dengan biakan darah positif, dan 32
neonatus dengan biakan usap telinga positif. Hanya 1 subjek yang memiliki
kesesuaian jenis kuman yang tumbuh dari biakan darah dan biakan usap telinga.
Bakteri yang tumbuh pada biakan usap telinga sebagian besar adalah Gram postif
(62%). Biakan usap telinga mempunyai sensitivitas 64,7%, spesifisitas 36,4%,
nilai duga positif 34,3%, nilai duga negatif 66,6%, rasio kemungkinan positif
1,02, rasio kemungkinan negatif 0,97, dan, akurasi 46% untuk mendeteksi SNAD.
Simpulan. Ditemukan hasil biakan darah positif pada 2 subjek. Biakan usap
telinga memiliki sensitivitas 64,7%, spesifisitas 36,4%, nilai duga positif 34,3%,
nilai duga negatif 66,6%, rasio kemungkinan positif 1,02, rasio kemungkinan
negatif 0,97, dan akurasi 46% untuk mendeteksi SNAD.

ABSTRACT
Background. Early-onset neonatal sepsis (EOS) is a clinical syndrome due to
systemic response to infection in early life. EOS is often difficult to diagnosed
because the clinical symptoms are not specific.
Objective. The study aim to determine sensitivity and specificity of ear swabs
culture in the diagnosis of EOS.
Methods. Neonates born in the CMH Jakarta and Tangerang Selatan Hospital
who developed sepsis were studied. Swabs were collected for culture from baby’s
ear. Bacterias isolated from ear swabs cultured were correlated with those from
blood culture.
Results. Among 50 neonates studied, 2 neonates had positive blood cultured and
32 neonates had positive ear swabs cultured. Only one subject had suitability
types of bacterias that grew from blood and ear swabs. Bacteria grew from ear
swab cultured were predominantly Gram-positive (62%). Ear swabs cultured had
sensitivity 64.7%, specificity 36.4%, positive predictive value (PPV) 34.3%,
negative predictive value (NPV) 66.6%, positive likelihood ratio (PLR) 1.02,
negative likelihood ratio (NLR) 0.97, and accuracy 46% to detect EOS.
Conclusions. This study showed positive blood culture results were found in two
subjects. Ear swabs cultured had a sensitivity 64.7%, specificity 36.4%, PPV
34.3%, NPV 66.6%, PLR 1.02, NLR 0.97, and accuracy 46% to detect EOS, Background. Early-onset neonatal sepsis (EOS) is a clinical syndrome due to
systemic response to infection in early life. EOS is often difficult to diagnosed
because the clinical symptoms are not specific.
Objective. The study aim to determine sensitivity and specificity of ear swabs
culture in the diagnosis of EOS.
Methods. Neonates born in the CMH Jakarta and Tangerang Selatan Hospital
who developed sepsis were studied. Swabs were collected for culture from baby’s
ear. Bacterias isolated from ear swabs cultured were correlated with those from
blood culture.
Results. Among 50 neonates studied, 2 neonates had positive blood cultured and
32 neonates had positive ear swabs cultured. Only one subject had suitability
types of bacterias that grew from blood and ear swabs. Bacteria grew from ear
swab cultured were predominantly Gram-positive (62%). Ear swabs cultured had
sensitivity 64.7%, specificity 36.4%, positive predictive value (PPV) 34.3%,
negative predictive value (NPV) 66.6%, positive likelihood ratio (PLR) 1.02,
negative likelihood ratio (NLR) 0.97, and accuracy 46% to detect EOS.
Conclusions. This study showed positive blood culture results were found in two
subjects. Ear swabs cultured had a sensitivity 64.7%, specificity 36.4%, PPV
34.3%, NPV 66.6%, PLR 1.02, NLR 0.97, and accuracy 46% to detect EOS]"
2015
T-Pdf
UI - Tesis Membership  Universitas Indonesia Library
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Muhammad Nuha Hafizh
"Latar belakang: Hingga saat ini, pneumonia merupakan salah satu penyebab utama kematian balita di dunia. Banyak faktor yang bisa berpengaruh terhadap peningkatan kejadian pneumonia pada balita, baik aspek individu dari anak itu sendiri, perilaku orang tua, dan lingkungan. Salah satu cara yang dapat digunakan untuk mencegah terjadinya pneumonia adalah vaksinasi Pneumococcal Conjugate Vaccine atau PCV
Tujuan: Mengetahui hubungan antara faktor pengetahuan, sosiodemografi, sikap, dan perilaku orangtua mengenai pneumonia, serta sikap orangtua terhadap vaksinasi dengan penerimaan orangtua terhadap Pneumococcal Conjugate Vaccine pada anak usia di bawah 5 tahun di Indonesia
Metode: Penelitian dilakukan di poliklinik departemen anak Rumah Sakit Cipto Mangunkusumo, dan TPA Makara UI pada November 2020. pengambilan sampel dilakukan secara consecutive sampling. Perhitungan jumlah sampel menggunakan rumus sampel tunggal. Kriteria inklusi adalah orangtua yang memiliki anak berusia di bawah 5 tahun serta mengisi kuesioner dengan lengkap. Data dianalisis berdasarkan usia, pendidikan, pekerjaan, penghasilan, pengetahuan, sikap, dan perilaku terhadap pneumonia, serta sikap terhadap vaksinasi. Uji yang digunakan adalah metode uji Chi-square untuk mengetahui hubungan dari faktor tersebut dengan penerimaan terhadap vaksinasi pneumonia.
Hasil: Sebanyak 97 (84,1%) dari 107 responden dalam penelitian ini menerima pemberian pneumococcal conjugate vaccine.Sikap orangtua terhadap vaksinasi memiliki hubungan yang signifikan dengan penerimaan orangtua terhadap vaksinasi pneumonia (p=0,000). sementara untuk usia orangtua (p=0,172), pendidikan orangtua (1,000), pekerjaan orangtua (p=0,119), penghasilan orangtua (p=0,617), serta pengetahuan (p=0,253), sikap (p=0,597) dan perilaku (p=1,000) terhadap penyakit pneumonia tidak memiliki hubungan yang signifikan dengan penerimaan orangtua terhadap vaksinasi pneumonia
Simpulan: Sikap orangtua terhadap vaksinasi dapat mempengaruhi penerimaan orang tua terhadap vaksinasi pneumonia

Background: Until now, pneumonia is one of the main causes of children under five mortality in the world, even in Indonesia. Many factors can influence the increase in the incidence of pneumonia in children under five, both in individual aspects of the child, the behavior of parents, and the environment. One way that can be used to prevent pneumonia is the Pneumococcal Conjugate Vaccine or PCV vaccination
Aim: To evaluate the relationship between knowledge, sociodemography, attitudes and behavior of parents regarding pneumonia, as well as parental attitudes towards vaccination and parental acceptance of Pneumococcal Conjugate Vaccine in children under 5 years of age in Indonesia.
Methods: The research was conducted at the Pediatric Department Polyclinic dr. Cipto Mangunkusumo Hospital, and Makara UI Children Day Care in November 2020. Sampling was carried out by consecutive sampling. The sample size calculation useds a single sample formula. The inclusion criteria were parents who had children under 5 years old and filled out a complete questionnaire. Data were analyzed based on age, education, occupation, income, knowledge, attitudes, and behavior towards pneumonia, as well as attitudes towards vaccination. The study used the Chi-square test method to determine the relationship between these factors and the acceptance of pneumonia vaccination.
Results: A total of 97 (84.1%) of the 107 respondents in this study accept pneumococcal conjugate vaccine. attitude towards vaccination had a significant correlation with parental acceptance of pneumonia vaccination (p = 0.000050). while for the parents age (p = 0.172), parental education (1,000), parent's job (p = 0.119), parental income (p = 0.625), as well as knowledge (p = 0.253), attitudes (p = 0.597) and behavior (p = 1,000) toward pneumonia did not have a significant correlation with parental acceptance of pneumonia vaccination
Conclusion : Parents attitudes towards vaccination showed signifigantly correlation to acceptance of pneumonia vaccination
"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2021
S-pdf
UI - Skripsi Membership  Universitas Indonesia Library
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Rampengan, Novie Homenta
"[Latar belakang. Infeksi virus hepatitis B (VHB) di Indonesia masih tinggi dengan rerata prevalensi 9,4%. Tingginya prevalensi HB ini terkait dengan terjadinya infeksi VHB pada masa dini kehidupan, terutama melalui transmisi vertikal. Di Indonesia proporsi transmisi vertikal 45,9% dan 5,2% ibu hamil HBsAgnya positif. Cara paling efektif mengontrol infeksi VHB adalah dengan imunisasi, namun terdapat perbedaan seroproteksi titer anti-HBs pada usia lebih dari 10 tahun di berbagai tempat. Selain itu terdapat faktor-faktor yang dapat memengaruhi titer anti-HBs, namun penelitian ini masih jarang dan belum pernah dilakukan di Manado.
Tujuan. Mengetahui seroproteksi titer anti-HBs dan faktor-faktor yang dapat memengaruhi titer anti- HBs tersebut.
Metode. Penelitian analitik observational dengan desain potong lintang. Penelitian dilakukan dengan stratified random sampling pada usia 10-15 tahun di Kecamatan Tuminting, Kota Manado sejak Oktober sampai November 2014. Data dianalisis dengan SPSS 22.
Hasil. Dari 48 sekolah terpilih 10 sekolah dengan 105 anak sebagai subyek penelitian, namun hanya 23 anak yang mempunyai seroprotektif (21,9%). Sebanyak 76 (72,4%) subyek adalah perempuan, 78 (74,3%) subyek berstatus gizi baik dan 98 (93,3%) subyek memiliki berat badan lahir ≥ 2.500 gram. Dari buku imunisasi didapatkan 26 (24,8%) subyek dengan vaksinasi HB-1 ≤ 7 hari dan 45 (42,9%) subyek dengan jarak HB-2 dan HB-3 ≥ 2 bulan. Didapatkan 86 (81,9%) ibu subyek berusia 20-35 tahun, 64 (60,9%) ibu subyek berpendidikan SMA dan 79 (75,2%) orangtua subyek berpenghasilan ≥ 2 juta per bulan. Analisis multivariat didapatkan faktor pemberian HB-1 < 7 hari atau ≥ 7 hari (p=0,02) dan jarak pemberian HB-2 dengan HB-3< 2 bulan atau ≥ 2 bulan (p<0,001) berperan terhadap seroproteksi HB pada anak.
Simpulan. Penelitian ini mendapatkan angka seroproteksi HB yang rendah (21,9%) serta faktor pemberian HB-1 ≤ 7 hari atau > 7 hari dan jarak pemberian HB-2 dengan HB-3 < 2 bulan atau ≥ 2 bulan berperan terhadap seroproteksi HB pada anak usia 10-15 tahun.;Background. Hepatitis B viral (HBV) infection in Indonesia is still high with average prevalence of 9.4%. The high prevalence of hepatitis B (HB) is related to the occurence of HBV infection during the early life, especially through vertical transmission. In Indonesia proportion of vertical transmission 45.9% and 5.2% pregnant women have HBsAg positive. The most effective way to control HBV infection is with immunization HB, but there is differential in anti-HBs seroprotection titer at the age more than ten years in many locations. In addition there are factors that can affect anti-HBs titer, but these studies are rare and have ever been done in Manado.
Objective. Knowing anti-HBs seroprotection titer and factors that can affect the anti-HBs titer.
Method. Analitic observational study with cross sectional design. Research was done with stratified random sampling in children age 10-15 years old at Tuminting district, Manado city since October until November 2014. Analise data with SPSS 22.
Results. From 48 schools, selected 10 schools with 105 children as subject of research, but only 23 (21.9%) children who were having seroprotective (21,9%). A total of 76 (72.4%) subjects were female, 78 (74.3%) subjects with good nutrition status and 98 (93.3%) subjects had ≥2,500 grams birth weight. From the immunization record book 26 (24.8%) subjects were obtained with HB-1 vaccination done at ≤7 days of age and 45 (42.9%) subjects with the distance between HB-2 and HB-3 were ≥2 months. Mother’s age was found 86 (81.9%) were 20-35 years old, 64 (60.9%) mothers’s education were high school graduated and 79 (75.2%) parents subjects had income ≥2 million per month. From multivariate analysis obtained that administration of HB-1 ≤7 days or >7 days (p=0.02) and distance between administration of HB-2 and HB-3 <2 months or ≥2 months (p<0.001) had important role in HB seroprotection in children.
Conclusion. This study obtained a number of low HB seroptotection (21.9%) as well as administration of HB-1 ≤7 days or >7 days and distance between administration of HB-2 and HB-3 <2 months or ≥2 months had important role in HB seroprotection in children age 10-15 years old., Background. Hepatitis B viral (HBV) infection in Indonesia is still high with average prevalence of 9.4%. The high prevalence of hepatitis B (HB) is related to the occurence of HBV infection during the early life, especially through vertical transmission. In Indonesia proportion of vertical transmission 45.9% and 5.2% pregnant women have HBsAg positive. The most effective way to control HBV infection is with immunization HB, but there is differential in anti-HBs seroprotection titer at the age more than ten years in many locations. In addition there are factors that can affect anti-HBs titer, but these studies are rare and have ever been done in Manado.
Objective. Knowing anti-HBs seroprotection titer and factors that can affect the anti-HBs titer.
Method. Analitic observational study with cross sectional design. Research was done with stratified random sampling in children age 10-15 years old at Tuminting district, Manado city since October until November 2014. Analise data with SPSS 22.
Results. From 48 schools, selected 10 schools with 105 children as subject of research, but only 23 (21.9%) children who were having seroprotective (21,9%). A total of 76 (72.4%) subjects were female, 78 (74.3%) subjects with good nutrition status and 98 (93.3%) subjects had ≥2,500 grams birth weight. From the immunization record book 26 (24.8%) subjects were obtained with HB-1 vaccination done at ≤7 days of age and 45 (42.9%) subjects with the distance between HB-2 and HB-3 were ≥2 months. Mother’s age was found 86 (81.9%) were 20-35 years old, 64 (60.9%) mothers’s education were high school graduated and 79 (75.2%) parents subjects had income ≥2 million per month. From multivariate analysis obtained that administration of HB-1 ≤7 days or >7 days (p=0.02) and distance between administration of HB-2 and HB-3 <2 months or ≥2 months (p<0.001) had important role in HB seroprotection in children.
Conclusion. This study obtained a number of low HB seroptotection (21.9%) as well as administration of HB-1 ≤7 days or >7 days and distance between administration of HB-2 and HB-3 <2 months or ≥2 months had important role in HB seroprotection in children age 10-15 years old.]"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2015
T58655
UI - Tesis Membership  Universitas Indonesia Library
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Deasy Grafianti
"[ABSTRAK
Latar belakang: Obat antiepilepsi (OAE), seperti asam valproat (valproic acid,
VPA) dan karbamazepin (carbamazepin, CBZ) sering digunakan dalam jangka waktu
panjang. Obat-obatan tersebut dapat mengganggu fungsi tubulus ginjal. N-acetylbeta-D-glucosaminidase
(NAG) urin merupakan enzim yang dapat dipakai sebagai
marka fungsi tubulus sehingga diharapkan dapat mendeteksi jejas tubulus. Penelitian
mengenai efek nefrotoksik VPA dan CBZ terhadap tubulus menggunakan penanda
NAG urin ini belum pernah dilakukan di Indonesia.
Tujuan: Mengukur indeks NAG (iNAG) urin pada anak epilepsi yang mendapat
VPA dan atau CBZ jangka panjang untuk mendeteksi efek nefrotoksik kedua OAE
tersebut pada tubulus ginjal.
Metodologi: Penelitian ini menggunakan studi potong lintang yang dilakukan pada
Januari-Maret 2015. Subjek penelitian ini adalah 36 anak epilepsi dengan monoterapi
VPA, 14 dengan monoterapi CBZ, 14 dengan kombinasi VPA dan CBZ, rentang usia
3-16 tahun. Pada seluruh subjek dilakukan pemeriksaan kadar kreatinin urin dan
kadar NAG urin. Sebagai nilai acuan kadar NAG urin, dipilih 30 anak sehat dengan
usia yang disesuaikan dengan subjek penelitian. Untuk menghilangkan variabilitas
harian, maka NAG urin dibagi dengan kreatinin urin, menjadi iNAG (satuan U/g
kreatinin). Indeks NAG dikategorikan meningkat bila nilainya lebih dari rerata NAG
+ 2 SD kelompok anak sehat.
Hasil: Rerata iNAG urin pada kelompok anak sehat, monoterapi VPA, monoterapi
CBZ dan kombinasi VPA dan CBZ berturut-turut adalah 3,01; 5,9; 4,07; 6,9. Tiap
kelompok kasus memiliki rerata iNAG urin lebih tinggi dibandingkan anak sehat.
Proporsi kenaikan iNAG urin ditemukan pada 11/ 36 anak dengan monoterapi VPA,
2/14 pada kelompok monoterapi CBZ, dan 9/14 pada terapi kombinasi VPA dan
CBZ.
Simpulan: Pemberian VPA jangka panjang dapat menyebabkan jejas pada tubulus ginjal dengan parameter kenaikan iNAG urin, dan jejas tubulus ini meningkat dengan pemakaian VPA dan CBZ secara kombinasi.ABSTRACT Background: Antiepileptic drugs such as valproic acid (VPA) and carbamazepine
(CBZ) are often used in the long term manner. These drugs may disrupt the function
of the kidney tubules. Urinary N-acetyl-beta-D-glucosaminidase (NAG) is an enzyme
that can be utilised as marker of tubular function and is therefore expected to be
useful in detecting kidney tubular injuries. There have been no studies conducted in
Indonesia on the nephrotoxic effect of VPA and CBZ to tubules using urinary NAG
as marker.
Objectives: To measure urinary NAG index (iNAG) in epileptic children with longterm
use of VPA and CBZ in order to detect their nephrotoxic effects on kidney
tubules.
Methods: This is a cross-sectional study performed on January to March 2015. The
subject includes 36 patients on VPA monotherapy, 14 patients on CBZ monotherapy,
and 14 patients on VPA-CBZ combination therapy with age ranging from 3 to 16
years old. Urine creatinine concentration and urinary NAG values of all the patients
are measured. Thirty age-adjusted healthy children are included in the study for NAG
value reference. To eliminate NAG diurnal variability, iNAG is calculated by
dividing urinary NAG value and urine creatinine concentration. Urinary iNAG values
that fall above the +2 standard deviations from the mean of healthy children are
considered elevated.
Results: Urinary iNAG values of the healthy children, VPA monotherapy, CBZ
monotherapy, and VPA-CBZ comination therapy groups are 3.01; 5.9; 4.07; 6.9 U/g
respectively. Each case group has higher urinary iNAG mean value than the control
group. Urinary iNAG urine increased proportion is found in 11/36 children on VPA
monotherapy, 2/14 children on CBZ monotherapy, and 9/14 children on VPA-CBZ
combination therapy.
Conclusions: Long-term VPA use may cause renal tubular injuries with increased urinary iNAG value as parameter. Tubular injury is increased with the use of VPA and CBZ in combination. ;Background: Antiepileptic drugs such as valproic acid (VPA) and carbamazepine
(CBZ) are often used in the long term manner. These drugs may disrupt the function
of the kidney tubules. Urinary N-acetyl-beta-D-glucosaminidase (NAG) is an enzyme
that can be utilised as marker of tubular function and is therefore expected to be
useful in detecting kidney tubular injuries. There have been no studies conducted in
Indonesia on the nephrotoxic effect of VPA and CBZ to tubules using urinary NAG
as marker.
Objectives: To measure urinary NAG index (iNAG) in epileptic children with longterm
use of VPA and CBZ in order to detect their nephrotoxic effects on kidney
tubules.
Methods: This is a cross-sectional study performed on January to March 2015. The
subject includes 36 patients on VPA monotherapy, 14 patients on CBZ monotherapy,
and 14 patients on VPA-CBZ combination therapy with age ranging from 3 to 16
years old. Urine creatinine concentration and urinary NAG values of all the patients
are measured. Thirty age-adjusted healthy children are included in the study for NAG
value reference. To eliminate NAG diurnal variability, iNAG is calculated by
dividing urinary NAG value and urine creatinine concentration. Urinary iNAG values
that fall above the +2 standard deviations from the mean of healthy children are
considered elevated.
Results: Urinary iNAG values of the healthy children, VPA monotherapy, CBZ
monotherapy, and VPA-CBZ comination therapy groups are 3.01; 5.9; 4.07; 6.9 U/g
respectively. Each case group has higher urinary iNAG mean value than the control
group. Urinary iNAG urine increased proportion is found in 11/36 children on VPA
monotherapy, 2/14 children on CBZ monotherapy, and 9/14 children on VPA-CBZ
combination therapy.
Conclusions: Long-term VPA use may cause renal tubular injuries with increased urinary iNAG value as parameter. Tubular injury is increased with the use of VPA and CBZ in combination. , Background: Antiepileptic drugs such as valproic acid (VPA) and carbamazepine
(CBZ) are often used in the long term manner. These drugs may disrupt the function
of the kidney tubules. Urinary N-acetyl-beta-D-glucosaminidase (NAG) is an enzyme
that can be utilised as marker of tubular function and is therefore expected to be
useful in detecting kidney tubular injuries. There have been no studies conducted in
Indonesia on the nephrotoxic effect of VPA and CBZ to tubules using urinary NAG
as marker.
Objectives: To measure urinary NAG index (iNAG) in epileptic children with longterm
use of VPA and CBZ in order to detect their nephrotoxic effects on kidney
tubules.
Methods: This is a cross-sectional study performed on January to March 2015. The
subject includes 36 patients on VPA monotherapy, 14 patients on CBZ monotherapy,
and 14 patients on VPA-CBZ combination therapy with age ranging from 3 to 16
years old. Urine creatinine concentration and urinary NAG values of all the patients
are measured. Thirty age-adjusted healthy children are included in the study for NAG
value reference. To eliminate NAG diurnal variability, iNAG is calculated by
dividing urinary NAG value and urine creatinine concentration. Urinary iNAG values
that fall above the +2 standard deviations from the mean of healthy children are
considered elevated.
Results: Urinary iNAG values of the healthy children, VPA monotherapy, CBZ
monotherapy, and VPA-CBZ comination therapy groups are 3.01; 5.9; 4.07; 6.9 U/g
respectively. Each case group has higher urinary iNAG mean value than the control
group. Urinary iNAG urine increased proportion is found in 11/36 children on VPA
monotherapy, 2/14 children on CBZ monotherapy, and 9/14 children on VPA-CBZ
combination therapy.
Conclusions: Long-term VPA use may cause renal tubular injuries with increased urinary iNAG value as parameter. Tubular injury is increased with the use of VPA and CBZ in combination. ]"
Fakultas Kedokteran Universitas Indonesia, 2015
SP-PDF
UI - Tugas Akhir  Universitas Indonesia Library
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Aan Kurniawan
"ABSTRAK
Infeksi dengue merupakan masalah kesehatan di Indonesia. Kementrian Kesehatan RI melaporkan terdapat 71.668 laporan kasus demam berdarah dengue dan 641 kasus meninggal karena demam berdarah pada tahun 2014. Demam berdarah dapat dicegah, salah satunya dengan mengontrol transmisi vektor dengue. Efektifitas pencegahan dengue ditentukan oleh kesadaran dan partisipasi masyarakat dalam mencegah perkembangbiakan nyamuk dengue. Penelitian ini bertujuan untuk mengetahui hubungan antara faktor sosiodemografis usia, pendidikan, pekerjaan, dan penghasilan orangtua dengan pengetahuan, sikap, dan perilaku mereka terkait transmisi dan pencegahan dengue pada anak. Penelitian ini merupakan penelitian potong lintang menggunakan data primer yang diperoleh dari kuisioner yang diisi oleh subjek penelitian. Hasil penelitian didapatkan sebagai berikut: 51,7 orang tua berpengetahuan cukup baik, 96,3 bersikap baik, dan 63,2 berperilaku cukup baik. Pendidikan memiliki korelasi yang signifikan dengan pengetahuan orang tua terkait transmisi dan pencegahan dengue p= 0,05 . Sebaliknya usia, pekerjaan, dan penghasilan tidak memiliki hubungan signifikan p > 0,05 . Dapat disimpulkan bahwa hanya faktor pendidikan memiliki hubungan bermakna dengan pengetahuan subjek terkait transmisi dan pencegahan infeksi dengue pada anak. Diperlukan studi lanjutan dengan subjek dari provinsi lain agar hasil penelitian dapat diekstrapolasi pada populasi Jakarta dan juga diseminasi mengenai infeksi dengue yang lebih giat oleh pemerintah kepada masyarakat.

ABSTRACT
Dengue infection is a major health problem in Indonesia. The Ministry of Health of Indonesia reported 71,668 cases of dengue hemorrhagic fever and the resulting 641 deaths in 2014. Dengue fever can be prevented by taking preventive control measure to prevent transmission of dengue infection via its vector. The effectiveness of dengue prevention depends on community awareness and participation in eradicating or reducing breading site for mosquitos. This research aims to investigate the correlation between parents rsquo sociodemographic factors age, education, occupation, and income and their knowledge, attitude, and practice regarding dengue transmission and prevention in children. This is a cross sectional research using primary data taken from questionnaires filled by the respondents. The results were as follows 53 of parents have sufficient knowledge, 96 display good attitude, and 63.2 exhibit good practice regarding dengue transmission and prevention. Education has a significant correlation with parents rsquo knowledge regarding transmission and prevention p 0.05 , whereas age, occupation, and income do not have significant correlation p 0.05 . In conclusion, only education has a significant correlation with the subject rsquo s knowledge regarding dengue transmission and prevention. Futher study with greater subjects from every province in order to extrapolate the data into Jakarta rsquo s population and also more frequent dissemination of dengue infection from the government to the public are needed."
2017
S-Pdf
UI - Skripsi Membership  Universitas Indonesia Library
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Christian Johan
"ABSTRAK
Dengue merupakan masalah kesehatan penting di Indonesia. Pengenalan gejala dan penanganan anak tersangka infeksi dengue oleh orang tua sangat penting untuk memberikan tatalaksana yang tepat dan segera. Penelitian ini bertujuan untuk mengetahui hubungan faktor sosiodemografis dengan pengetahuan, sikap, dan perilaku orang tua mengenai gejala dan penanganan anak tersangka infeksi dengue di Jakarta Barat. Penelitian dilakukan secara potong lintang dengan menggunakan kuesioner pada 267 orang tua di Jakarta Barat. Hasil penelitian menunjukkan subjek dengan pengetahuan sangat baik berjumlah 19.9 , baik berjumlah 32.2 , kurang berjumlah 30.3 , dan sangat kurang berjumlah 17.6 . Kebanyakan subjek memiliki sikap dan perilaku mengenai penanganan anak tersangka infeksi dengue yang sangat baik 31.1 dan baik 55.4 , namun masih terdapat 13.5 subjek dengan sikap dan perilaku kurang. Berdasarkan uji korelasi Spearman, pendidikan p=0.006 dan pekerjaan p=0.032 memiliki hubungan bermakna dengan pengetahuan. Namun, faktor sosiodemografis tidak memiliki hubungan bermakna dengan sikap dan perilaku orang tua mengenai anak tersangka infeksi dengue p>0.05.

ABSTRACT
Dengue is a public health concern in Indonesia. It is important for parents to be able to recognize symptoms and to properly treat children with suspected dengue infection. This research defined the relationship between sociodemographic factors and parents rsquo knowledge, attitude, and behavior regarding symptoms and treatment of children with suspected dengue infection in West Jakarta. A cross sectional questionnaire survey of 267 parents was conducted in West Jakarta. The respondents rsquo knowledge was as follows very good 19.9 , good 32.2 , poor 30.3 , very poor 17.6 . A majority of respondents had good 55.4 and very good 31.1 attitude and behavior while the remaining 13.5 had poor attitude and behavior. Education p 0.006 and employment p 0.032 factors were found to have significant correlation with parents rsquo knowledge. This study also showed that sociodemographic factors did not have significant correlation with parents rsquo attitude and behavior regarding treatment of children with suspected dengue infection p 0.05 . "
2017
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UI - Skripsi Membership  Universitas Indonesia Library
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Ignatius Rudianto
"ABSTRAK
Terdapat berbagai cara yang dapat dilakukan untuk mencegah infeksi dengue, salah satunya adalah vaksinasi. Vaksin CYD-TDV Chimeric yellow fever virus-Dengue virus-Tetravalent Dengue Vaccine merupakan vaksin dengue pertama yang diterima oleh WHO dan telah diterima juga untuk didistribusikan ke berbagai negara, salah satunya adalah Indonesia. Penelitian ini bertujuan untuk melihat berbagai faktor yang mungkin berpengaruh terhadap penerimaan orang tua terhadap pemberian vaksin dengue pada anak, seperti faktor sosiodemografis, serta pengetahuan, sikap dan perilaku orang tua. Penelitian ini juga menunjukkan preferensi orang tua mengenai vaksin dengue. Desain penelitian yang digunakan adalah desain cross-sectional dengan data primer yang didapatkan dari pengisian kuisioner oleh subjek penelitian. Hasil penelitian menunjukkan: 98,50 responden menerima pemberian vaksin dengue kepada anak mereka. Sementara itu, tidak ditemukan faktor yang memiliki hubungan signifikan terhadap penerimaan orang tua terhadap pemberian vaksin dengue pada anak p >0,05. Sebagian besar subjek penelitian 35,96 berpendapat bahwa perlindungan pasti sebagai hal terpenting dari vaksin dengue. Sementara itu, 56,93 responden yang menilai biaya sama dengan atau kurang dari Rp 50.000,00 merupakan harga yang terjangkau. Berdasarkan penelitian ini, penerimaan orangtua terhadap vaksin relatif baik.

ABSTRACT
There are ways to prevent dengue infections, one of which is by receiving vaccination. CYD TDV Chimeric yellow fever virus Dengue virus Tetravalent Dengue Vaccine was the first vaccine to be accepted by the World Health Organization to be distributed worldwide, including Indonesia. This study aimed to explore factors which might contribute to parents 39 acceptance of their children being subject of dengue vaccinations. This study also shows parents 39 preference of the most important characteristics of dengue vaccines. The study design applied was cross sectional study with primary data collected from questionnaire filled by study subjects. This study shows 98.5 respondents accept dengue vaccination for their children. Meanwhile, this study found no factor which has significant relation to parents 39 dengue vaccine acceptance p 0.05. The most popular preference for the most important vaccine characteristic was 100 protection 35.96 . Meanwhile, 56.93 of all respondents categorized vaccination costs of IDR 50,000.00 and below as affordable. According to the result of the research, parents 39 vaccine acceptance in Jakarta could be considered relatively good."
2017
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UI - Skripsi Membership  Universitas Indonesia Library
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Tania Paramita
"Latar belakang: Pengukuran suhu tubuh sebenarnya (core body temperature) tidak lazim dilakukan pada anak karena invasif dan sulit, sehingga pengukuran suhu aksila dan membran timpani lebih disukai. Namun sampai saat ini ketepatan hasil pengukuran suhu membran timpani dan aksila masih diperdebatkan.
Tujuan: Membandingkan ketepatan hasil pengukuran suhu membran timpani dan aksila dengan rektal, mengetahui metode terbaik pengukuran suhu tubuh, dan cut off demam pada anak berdasarkan masing-masing metode pengukuran suhu.
Metode: Penelitian diagnostik potong lintang pada anak demam berusia 6 bulan ? 5 tahun yang dipilih secara konsekutif di Poliklinik Anak, IGD Anak, dan Ruang Perawatan Anak Gedung A RSCM antara bulan Desember 2014 ? Januari 2015.
Hasil: Dengan cut off demam suhu aksila 37,4oC dan membran timpani 37,6oC didapatkan sensitivitas 96% (IK 95% 0,88-0,98) dan 93% (IK 95% 0,84-0,97), spesifisitas 50% (IK 95% 0,47-0,84) dan 50% (IK 95% 0,31-0,69), NDP 90% (IK 95% 0,81-0,95) dan 85% (IK 95% 0,75-0,91), NDN 83% (IK 95% 0,61-0,94) dan 69% (IK 95% 0,44-0,86). Cut off optimal demam suhu membran timpani dan aksila pada penelitian ini adalah 37,8oC (AUC 0,903 dan 0,903).
Simpulan: Hasil pengukuran suhu aksila sama baik dengan membran timpani dalam mendeteksi demam dan dapat digunakan dalam praktik klinis sehari-hari maupun di rumah. Dengan cut off demam 37,8oC didapatkan sensitivitas 81% dan 88%, spesifisitas 86% dan 73%, NDP 95% dan 91%.

Background: Core body temperature measurement is not common in pediatric population because it is invasive and difficult. Therefore tympanic and axillary temperature measurement are prefereble but their accuracy still debated.
Objective: To compare the accuracy of axillary and tympanic temperature to rectal temperature in children with fever and measure the cut off point for fever based on each temperature measurement method.
Methods: A cross-sectional diagnostic study was conducted among children age 6 months ? 5 years which was selected consecutively at Pediatric Out-patient clinic, Pediatric emergency unit, and the in-patient wards in building A RSCM from December 2014 to January 2015.
Results: With the cut off for fever on axilla 37,4oC and tympanic membrane 37,6oC the sensitivity was 96% (95% CI 0,88-0,98) and 93% (95% CI 0,84-0,97), specificity 50% (95% CI 0,47-0,84) and 50% (95% CI 0,31-0,69), NDP 90% (95% CI 0,81-0,95) and 85% (95% CI 0,75-0,91), NDN 83% (95% CI 0,61-0,94) and 69% (95% CI 0,44-0,86). Optimal cut off of tympanic membrane and axilla temperature was 37,8oC (AUC 0,903 dan 0,903).
Conclusions: Axillary temperature measurement is as good as the tympanic membrane temperature measurement and can be used at the daily clinical practice or at home. By increasing the optimum fever cut off point for axilla temperature and tympanic membrane to 37,8oC, we found sensitivity 81% and 88%, specificity 86% and 73%, NDP 95% and 91%."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2015
T58925
UI - Tesis Membership  Universitas Indonesia Library
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Nicolas
"Pendahuluan
Varicella merupakan penyakit dengan tingkat penularan tinggi yang dapat dicegah
dengan vaksinasi. Penelitian ini bertujuan mengevaluasi penerimaan orangtua
terhadap vaksinasi varicella bagi anak berusia di bawah 12 tahun, yang belum
pernah diteliti di Indonesia sebelumnya.
Metode Sampel penelitian merupakan orangtua yang dipilih secara consecutive sampling.
Perhitungan jumlah sampel menggunakan rumus sampel tunggal. Kriteria inklusi
adalah orangtua yang memiliki anak berusia di bawah 12 tahun. Kriteria eksklusi
adalah orangtua yang tidak mengisi kuesioner dengan lengkap atau mengundurkan
diri dari penelitian. Data ditabulasi berdasarkan usia, pendidikan, pekerjaan,
penghasilan, pengetahuan, sikap, dan perilaku terhadap varicella, serta sikap
terhadap vaksinasi. Uji yang digunakan adalah metode uji Chi-square untuk
mengetahui hubungan dari faktor tersebut dengan penerimaan terhadap vaksinasi
varicella.
Hasil
Dari 113 responden, 12 (10,6%) menolak pemberian vaksinasi varicella bagi anak
mereka. Terdapat 47% responden yang memiliki pengetahuan kurang, 22,1%
memiliki sikap kurang, dan 4,4% memiliki perilaku kurang terhadap varicella.
Terdapat pula 5,3% responden yang memiliki sikap kurang terhadap vaksinasi.
Didapatkan hubungan yang signifikan antara sikap orangtua terhadap vaksinasi
dengan penerimaan orangtua terhadap vaksinasi varicella (p = 0,000). Tidak
terdapat hubungan yang signifikan antara usia (p = 0,108), pendidikan (p = 0,627),
pekerjaan (p = 0,138), penghasilan (p = 0,479), pengetahuan (p = 0,820), sikap (p
= 0,460), dan perilaku terhadap varicella (p = 0,087) dengan penerimaan vaksinasi
varicella.
Kesimpulan
Sikap orangtua terhadap vaksinasi memiliki hubungan yang signifikan dengan
penerimaan vaksinasi varicella.

Introduction
Varicella is a highly contagious disease that could be prevented by vaccination.
This study aims to evaluate the parents’ acceptance of vaccination for their children
under 12 years old in Indonesia, which there’s no similar study performed before.
Methods
The samples of this study were parents who were chosen by consecutive sampling.
The inclusion criterias were the parents who have children under 12 years. The
exclusion criterias are parents who did not fill all the questions or those who
resigned from the study. Data were tabulated based on age, education, occupation,
income, knowledge, attitude, and behavior towards varicella, and attitude towards
vaccination. Method used in this study to analyze the data was Chi-square test to
find correlation between those factors with varicella vaccination acceptance.
Results
Of the 113 respondents, 12 (10,6%) rejected varicella vaccination for their children.
There were 47% respondents with bad knowledge, 22,1% with bad attitude, and
4,4% with bad behavior toward varicella. There were also 5,3% respondents with
bad attitude toward vaccination. There was a significant correlation between
parental attitude toward vaccination with varicella vaccination acceptance (p =
0,000). There was no significant correlation between parental age (p = 0,108),
education (p = 0,627), occupation (p = 0,138), income (p = 0,479), knowledge (p =
0,820), attitude (p = 0,460), and behavior (p = 0,087) toward varicella with varicella
vaccination acceptance.
Conclusion Parental attitude toward vaccination have a significant correlation with varicella
vaccination acceptance.
"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2021
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UI - Skripsi Membership  Universitas Indonesia Library
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Muhammad Rayyan Faher Shahab
"Pendahuluan: Rotavirus merupakan virus dengan tingkat penularan tinggi pada anak di bawah usia 5 tahun yang dapat dicegah dengan vaksinasi. Penelitian ini merupakan penelitian pertama di Indonesia yang bertujuan mengevaluasi penerimaan orangtua terhadap vaksinasi rotavirus bagi anak berusia di bawah 5 tahun.
Metode: Sampel penelitian merupakan orangtua yang dipilih secara consecutive sampling. Perhitungan jumlah sampel menggunakan rumus sampel tunggal. Kriteria inklusi adalah orangtua yang memiliki anak berusia di bawah 5 tahun serta mengisi kuesioner dengan lengkap. Kriteria eksklusi adalah orangtua yang tidak mengisi kuesioner dengan lengkap atau mengundurkan diri dari penelitian. Data ditabulasi berdasarkan usia, pendidikan, pekerjaan, penghasilan, pengetahuan, sikap, dan perilaku terhadap rotavirus, serta sikap terhadap vaksinasi. Uji yang digunakan adalah metode uji Chi-square untuk mengetahui hubungan dari faktor tersebut dengan penerimaan terhadap vaksinasi rotavirus.
Hasil: Dari 108 responden, 13 (12%) menolak pemberian vaksinasi rotavirus bagi anak mereka. Didapatkan hubungan yang signifikan antara sikap orangtua terhadap vaksinasi dengan penerimaan orangtua terhadap vaksinasi rotavirus (p = 0,000). Tidak terdapat hubungan yang signifikan antara usia (p = 0,375), pendidikan (p = 0,636), pekerjaan (p = 0,500), penghasilan (p = 0,290), pengetahuan (p = 1,000), sikap (p = 0,689), dan perilaku terhadap rotavirus (p = 0,592) dengan penerimaan vaksinasi rotavirus.
Kesimpulan: Sikap orangtua yang positif terhadap vaksinasi berhubungan secara signifikan dengan penerimaan vaksinasi rotavirus.

Introduction: Rotavirus is a highly spread virus in children under 5 years old that could be prevented by vaccination. This study was the first performed in Indonesia to evaluates the parents’ acceptance towards rotavirus vaccination.
Methods: The samples of this study are parents who were chosen by consecutive sampling. The inclusion criterias are the parents who have children under 5 years old and have completed the questionnaire. The exclusion criterias are parents who did not fill all the questions or those who resigned from the study. Data are tabulated based on age, education, occupation, income, knowledge, attitude, and behavior towards rotavirus, and attitude towards vaccination. Method used in this study to analyze the data is Chi-square test to find correlation between those factors with rotavirus vaccination acceptance.
Results: Of the 108 respondents, 13(12%) rejected the acceptance towards rotavirus vaccination. There was a significant correlation between parental attitude towards vaccination with rotavirus vaccination acceptance (p = 0,000). There were no significant correlation between parental age (p = 0,375), education (p = 0,636), occupation (p = 0,500), income (p = 0,290), knowledge (p = 1,000), attitude (p = 0,689), and behavior (p = 0,592) toward rotavirus with rotavirus vaccination acceptance.
Conclusion: Parental positive attitude toward vaccination showed significant correlation with rotavirus vaccination acceptance.
"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2020
S-pdf
UI - Skripsi Membership  Universitas Indonesia Library
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