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"Background. Antibody to complement C1q (Anti-C1q Antibody) can be found in Systemic Lupus Erythematosus (SLE) patients. Complement C1q plays a role in the clearance of apoptotic cells and immune complexes. Anti-C1q causes complement C1q become inactive so that the clearance decreases, which induces self antigen and inflammatory response. Many tissue inflammation are associated with disease activity and lupus manifestations. The aim of this study is to find out the correlation of anti-C1q level with disease activity, so that anti-C1q can be used as an objective indicator of inflammation along with SELENA-SLEDAI. Method. This is an analytic descriptive study with cross sectional design. Anti-C1q antibody levels were measured in 52 SLE patients who are hospitalized or treated routinely in outpatient clinic of Rheumatology Dr.Hasan Sadikin Hospital Bandung Indonesia from October to December 2015. Result. Most of the study subjects were women (94%), with a median age of 33 years. There were 13 new patients (25%), and the rest 42 patients were treated routinely. The median SELENA-SLEDAI was 6 (0-32). Subject were divided into no activity (11.5%), low disease activity (34.6%), medium disease activity (25%) high disease activity (15.4%) and very high disease activity (13.5%). Median anti-C1q level was 3.92 U/mL (range 0.6-100.2 U/mL). Anti-C1q antibody levels were positively correlated with SLE disease activity based on SELENA-SLEDAI scores (r=+0.304; p=0.014) Conclusion. Anti-C1q antibody levels has mild correlated with lupus disease activity based on SELENA-SLEDAI score"

"ABSTRAKArtikel ini meneliti perkembangan agensi perempuan dari tokoh utama perempuan pada film Joy dan Selena yang berhubungan dengan perkembangan moral mereka yang pada akhirnya berkrontribusi pada tingkat agensi yang mereka miliki. Tujuan dari artikel ini adalah untuk menemukan tipe perkembangan dan perubahan agensi dan moral seperti apa yang harus mereka alami sehingga mereka dapat memiliki agensi yang seutuhnya. Selain itu, artikel ini juga dimaksudkan untuk mengetahui apakah kedua tokoh wanita tersebut memiliki tingkat agensi yang sama. Melalui analisis percakapan dari kedua film, artikel ini akan menunjukkan kuat dan lemahnya agensi dari tiap karakter di saat mereka menghadapi cobaan hidup. Untuk itu tahap-tahap kehidupan kedua tokoh tersebut, masa kanak-kanak dan saat mereka dewasa dibahas. Karena memiliki latar belakang dan kondisi keluarga yang sangat berbeda, Joy dan Selena harus menghadapi tekanan-tekanan hidup yang berbeda pula. Ketika dihadapkan dengan masalah, dua tahap perkembangan moral pada diri tiap karakterlah yang mempengaruhi cara mereka mengambil keputusan. Hal ini memiliki efek yang berbeda pada kualitas agensi mereka walaupun pada akhir cerita hidup mereka, mereka sama-sama menjadi wanita yang sukses meraih mimpi.

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ABSTRACTThis article examines the development of female agency related to the stages of moral development happening in the main female characters of Joy 2015 and Selena 1997 , which later is contributed to their level of agency. It aims at finding out what kind of change in the agency and moral development of each characters that they have to experience in order to have their full agency, and whether the agency are of the same level or not. Through a conversation analysis from the two films, this article will show the highs and lows of the characters rsquo; agency as they face obstacles in their life. In an effort to identify this, the research is focusing on Joy rsquo;s and Selena rsquo;s stages of life: childhood and adulthood. Coming from a completely different family background and condition, Joy and Selena must face different suppressions in their life. At this point, the two stages of moral development from each characters influence the way they solve the problems. This means it can affect their agency rsquo;s quality differently even though in the end, both can successfully reach their dreams."