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"Tujuan : untuk memperoleh data profil lipid dan kadar glukosa darah penderita SH, serta hubungannya dengan asupan makanan dan status gizi.Tempat : RS Sumber Waras, Jakarta Barat. Bahan dan Cara : Setelah mendapat izin dari Komite medik RS Somber Waras, maka dilakukan penelitian dengan desain cross sectional pada 140 penderita SH(100 laki-laki dan 40 perempuan) yang sesuai dengan kriteria penerimaan. Data yang dikumpulkan meliputi umur, jenis kelamin, analisis asupan makanan selama 3 hari di RS, antropometri (TLT&LLA), USG dan pemeriksaan laboratorium darah (profil lipid, kadar glukosa puasa & 2 jam PP). Uji statistik yang digunakan adalah t-test, Mann Whitney, Kolmogorov-Smimov dan uji korelasi Pearson /Spearman rank.Hasil : Subyek penelitian berjumlah 140 orang (100 laki-laki dan 40 perempuan), 59,3 % subyek memenuhi kriteria Child C, dengan menggunakan parameter AOLA menunjukkan 70,98% subyek Child B dan 75,90% subyek Child C memiliki status gizi muscle wasting. Pada pemeriksaan profit lipid didapatkan hasil kadar kolesterol total <200mg/dL,.LDL < 130 mg/dL, HDL < 40 mg/dL dan trigliserida < 200 mg/dL pada subyek Child B dan C. Profit lipid Child C lebih rendah dari Child B ( semakin luas kerusakan jaringan hati, terdapat gangguan sintesis lipid). Tidak terdapat hubungan bermakna antara profil lipid dengan status gizi, tidak terdapat hubungan bermakna antara status gizi dengan jumlah asupan makanan. Terdapat korelasi positif antara kadar trigliserida dengan jumlah asupan makanan subyek Child B dan korelasi positif antara kadar HDL dengan jumlah asupan makanan subyek Child C. Terdapat korelasi positif antara kadar glukosa darah puasa dengan kadar glukosa darah 2 jam post prandial. KES1MPULAN : Rendahnya profil lipid pada subyek Child B dan C diduga karena asupan makanan yang kurang dari kebutuhan dan status gizi muscle wasting, disamping kerusakan sel hati yang luas, menyebabkan defisiensi sejumlah enzim LCAT dan hepatic lipase. Ditemukannya peningkatan kadar glukosa darah 2 jam post prandial (>I44mg/dL) pada subyek Child B dan C.

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Objective : to obtain data about the lipid profile and blood sugar level in patients with cirrhosis hepatic and its relation to the food intake and nutritional status.

Place: Sumber Waras Hospital, West Jakarta

Materials and methods: after receiving permission from the Medical committee of Sumber Waras hospital. Crosses sectional study was done with 140 cirrhosis hepatize patients (100 males and 40 females) as the subjects fulfilling the criteria set for the study. The data colleted consisted of age,sex,analysis of 3 days food consumption in the hospital, anthropometric measurements('[SF&MUAC), USG and blood laboratory examination (lipid profile, blood sugar fasting & 2 hours post prandial). The following tests were used for data analysis t -test, Mann whitney, Koimogorov-Smirnov and Pearson/Spearman rank.

The results: Of the 140 subjects 59,3% fulfilled Child C critera who, based on MAMA parameter, were classified as Child B subjects (70,98 %) and Child C subjects (75,90) with muscle wasting. The lipid profile was as follows. Total cholesterol < 200mg/dL; LDL < 130 mgldL, HDL < 40 mg/dL and triglyceride <200 mg/dL in Child B and C subjects. The lipid profile of Child C subjects was lower than Child B(in extensive liver tissue damage synthesis is disturbed). There is no significant relation between the lipid profile and nutritional status, and between nutritional status with food intake. There is positive correlation between blood triglyceride level and food intake of Child 13 subjects and between blood HDL level with food intake of Child B subjects. There was also positive con-elation between fasting blood glucose level and 2 hours post prandial blood sugar.

Conclusion: the low level of lipid profile of subject Child B and C subjects are assumed to be related insufficient food intake and muscle wasting besides extensive liver tissue damage which lead to a deficiency of a number of LCAT enzymes and hepatic lipase. The increase in the 2 hours post prandial blood glucose level (>140 mg/dL) of the Child B and C subjects."

"ABSTRAKVital exhaustion (VE) merupakan prediktor utama terjadinya infark miokard (IM),diduga kepribadian tipe-D mempunyai hubungan independen dengan VE. Hubungankepribadian tipe-D, faktor fisiologi: kolesterol total, indeks masa tubuh (IMT), highdensity lipoprotein (HDL), low density lipoprotein (LDL), dan tekanan darahdiastolik (TDD), serta faktor gaya hidup dengan VE, telah diungkapkan olehbeberapa ahli namun belum jelas. Penelitian ini bertujuan untuk mengindentifikasihubungan antara kepribadian tipe-D dan faktor fisiologi berbungan dengan terjadinyaVE pada pasien IM. Penelitian ini menggunakan metoda cross sectional designs.Dengan jumlah sampel sebanyak 68 yang dipilih menggunakan teknik consecutivesampling pada subjek yang datang dirawat di ICCU RSUPN Cipto Mangunkusumodan Gedung Perawatan lantai 3,4, dan 5 RSJPD Harapan Kita Jakarta. Hasilpenelitian membuktikan kepribadian tipe D, kolesterol total dan TDD berhubungansignifikan dengan VE dan faktor yang paling berhubungan dengan VE adalahkepribadian tipe-D. p=0,01α:0,05, OR 6,83 (CI:1,58-29,48). Simpulan penelitian iniyaitu pasien IM yang berkepribadian tipe-D mempunyai peluang 6,8 kali mengalamiVE dibanding pasien IM bukan tipe-D setelah dikontrol oleh kolesterol total, TDDdan peminum minuman keras, dan pasien dengan kolesterol total berisiko berpeluang5,9 kali mengalami VE dibanding dengan kolesterol total tidak berisiko setelahdikontrol oleh tipe-D, TDD, dan peminum minuman keras, serta pasien dengan TDDberisiko berpeluang 5,7 kali mengalami VE setelah dikontrol TDD tidak berisiko,kolesterol total dan tipe-D. Rekomendasi penelitian adalah memasukkan kepribadiantipe-D dan VE, dalam format pengkajian asuhan keperawatan di setiap setingpelayanan pada pasien dengan penyakit jantung koroner.

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ABSTRACTVital exhaustion is a predictor to myocardial infarction, and personality type -D is independent to vital exhaustion. According to researches about Vital exhaustion related to personality type-D, physiologic factors such as total cholesterol, body mass index (BMI), high density lipoprotein (HDL), low density lipoprotein (LDL), anddiastolic blood pressure (DBP) and also life style, stile not clear. The aim of this study was to identified relationship between personality type-D and physiologic factors with vital exhaustion to the patients of myocardial infarction (MI). This study used a cross sectional designs with 68 subject, that was taken with a consecutive sampling at ICCU room in Cipto Mangunkusumo National CenterHospital and the third, fourth, and fifth floor of Nursing care building at National Cardiovascular Center Harapan Kita Jakarta. The results of this study were type-D personality, total cholesterol, and diastolic blood pressure statistically significant related to vital exhaustion. Type D personality was dominant statistically significant to vital exhaustion p=0,01α:0,05, OR 6,83 (95% CI:1,58-29,48). The researcher concluded that were MI patients with type-D personality have 6,8 times to become vital exhaustion than without type-D, and MI patients with risk of cholesterol total have 5,9 times to become vital exhaustion than without risk of cholesterol total,and MI patients with risk of DBP have 5,7 times to become vital exhaustion than without risk of DBP after adjusted by without type-D, cholesterol total and consume alcohol. Recommendation of this study is to submitted personality type-D and vital exhaustion assessment in form of nursing care for patient heart coronary disease in all health care setting."