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Hasil Pencarian

Ditemukan 3 dokumen yang sesuai dengan query
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Sinchai Chaikham; Jakkrit Buatana; Mattawan Meethangdee; Jarinya Luang-apirom; Napatjaree Sopin; Kitipong Jantabut; Chiraphat Kloypan; Serm Surapinit; Nuttakom Baisaeng
Alkaloids from Nauclea orientalis Inhibited in vitro ADP and Thrombin Induced Human Platelet Aggregation / Sinchai Chaikham, Jakkrit Buatana, Mattawan Meethangdee, Jarinya Luang-apirom, Napatjaree Sopin, Kitipong Jantabut, Chiraphat Kloypan, Serm Surapinit, Nuttakom Baisaeng
" A series of alkaloids isolated from the roots of N. orientalis is investigated for the inhibitory activities on in vitro agonists induced human platelet aggregation. Human platelet samples were obtained to investigate the anti-platelet activity by high throughput 96-well microtiter plate format. Adenosine diphosphate (ADP), arachidonic acid (AA), thrombin and thrombin receptor activating peptide-6 (TRAP-6) were used as agonists for in vitro human platelet aggregation. All alkaloids were inactive in the AA induced platelet aggregation. ... "
Thammasat Printing House, 2017
500 TIJST 22:1 (2017)
Artikel Jurnal  Universitas Indonesia Library
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Muhammad Begawan Bestari
Aspirin vs. P2Y12 inhibitor rivalry: which one can be continued during gastrointestinal bleeding
" Dual antiplatelet therapy (DAPT) is the mainstay of secondary prevention treatment for acute coronary syndrome (ACS) and ischemic stroke, especially after coronary intervention. DAPT consists of aspirin and P2Y12 receptor inhibitor (e.g. clopidogrel), and the use of DAPT has been increased over time. The most serious and common adverse effect is gastrointestinal bleeding. Guidelines in managing such condition are available among Gastroenterologist Societies and Cardiologist Societies. Most guidelines are consistent with each other to continue ... "
Jakarta: University of Indonesia. Faculty of Medicine, 2019
610 UI-IJIM 51:3 (2019)
Artikel Jurnal  Universitas Indonesia Library
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Indra Nurhidayat
Studi kinetika bromelain hasil fraksionasi parsial menggunakan kromatografi gel filtrasi dari nanas Palembang (ananas comosus [l] merr) dan uji aktivitasnya sebagai agen anti agregasi platelet = Kinetic studies of bromelain purificated from pineapple (ananas comosus [l] merr)using gel filtration chromatography and its activity as anti platelet agregation
" ABSTRAK
Pada penelitian ini, dilakukan studi kinetika dan aktivitas anti platelet bromelain yang telah dimurnikan dari bonggol nanas Palembang Ananas comosus [L] Merr . Pemurnian enzim dimulai dengan isolasi enzim bromelain, kemudian dilakukan fraksionasi bertingkat menggunakan garam amonium sulfat dan dilanjutkan dengan kromatografi gel filtrasi dengan Sphadex G-50. Enzim kasar yang didapatkan dari tahap isolasi memilki aktivitas spesifik sebesar 53,580 Unit/mg. Fraksionasi dengan metode fraksinasi bertingkat menggunakan garam amonium sulfat menghasilkan fraksi enzim yang memiliki aktivitas ... "
2017
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UI - Skripsi Membership  Universitas Indonesia Library