Ditemukan 1 dokumen yang sesuai dengan query
Steven
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Development and Validation of Cyclophosphamide and
4-Hydroxycyclophosphamide Quantification Method in
Volumetric Absorptive Microsampling (VAMS) by Liquid
Chromatography - Tandem Mass Spectrometry
......Cyclophosphamide is an anticancer alkylating prodrug, metabolized by CYP450 into its active metabolite, named 4-hydroxycyclophosphamide (4-OHCP). Its therapeutic effectiveness is determined by the 4-OHCP concentration. Several analytical methods using plasma and Dried Blood Spot have been developed to analyze cyclophosphamide and 4-OHCP. However, there are lots of disadvantages. Therefore, this study was conducted to develop a validated cyclophosphamide ...
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Depok: Fakultas Farmasi Universitas Indonesia, 2021
S-pdf
UI - Skripsi Membership Universitas Indonesia Library
