Ditemukan 2 dokumen yang sesuai dengan query
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This book addresses all the current, up-to-date developments in this scientific discipline. Liver is the chief metabolizing site in the body, and thus, it is a major target organ for drug and chemical toxicity. Therefore, hepatotoxicity is an important endpoint in the safety evaluation of drugs and chemicals.
Contributions from leading investigators in hepatotoxicity research address current developments in this scientific discipline and discuss use of current cutting edge technology such as microarrays in hepatotoxicity thus ...
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Chichester, West Sussex, England: John Wiley & Sons, 2007
e20395854
eBooks Universitas Indonesia Library
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This book examines genotoxic impurities and their impact on the pharmaceutical industry.Specific sections examine this from both a toxicological and analytical perspective. Within these sections, the book defines appropriate strategies to both assess and ultimately control genotoxic impurities, thus aiding the reader to develop effective control measures. An opening section covers the development of guidelines and the threshold of toxicological concern (TTC) and is followed byasection on safety aspects, including safety tests in vivo and ...
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Hoboken: John Wiley & Sons, 2010
e20393941
eBooks Universitas Indonesia Library
