Ditemukan 3 dokumen yang sesuai dengan query
Klebl, Bert.
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This timely guide to kinase inhibitor drug development is the first to cover the entire drug pipeline, from target identification to compound development and clinical application. Edited by the pioneers in the field, on the drug development side this ready reference discusses classical medicinal chemistry approaches as well as current chemical genomics strategies. On the clinical side, both current and future therapeutic application areas for kinase inhibitor drugs are addressed, with a strong focus on ...
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Weinheim: Wiley-VCH, 2011
e20394589
eBooks Universitas Indonesia Library
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Many researchers believe that GSK-3 and its inhibitors could lead to effective treatments for neurogenerative disorders, type II diabetes, depression and bipolar disorder, and some forms of cancer. This book provides a thorough introduction to GSK-3, presents up-to-date information, and mentions the birth of several chemical families of GSK-3 inhibitors with varying selectivity. It's a great reference for researchers in drug design and development ...
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Hoboken, New Jersey: Wiley-Interscience, 2006
e20395898
eBooks Universitas Indonesia Library
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This book provides an overview of different protein kinases, structure, function, regulation, and their role in cancer. It combines kinase biology with chemistry and pharmacology applications for discovery and development of cancer drugs. The text also describes existing and emerging kinase inhibitors, focusing mostly on small molecules but also alternative approaches like therapeutic antibodies. Provides an important resource that helps pharmaceutical researchers understand and work in this dynamic area of cancer drug research ...
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Hoboken, New Jersey: John Wiley & Sons, 2010
e20394639
eBooks Universitas Indonesia Library