Ditemukan 6 dokumen yang sesuai dengan query
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The human population is heterogeneous and consists of populations of immense ethnic diversity. There are considerable allelic differences between human populations as well as individuals within each ethnic group as a result of molecular heterogeneity of the genome. This, in turn, is responsible for differential allelic expression
of genes endowing them with polymorphic characters. The molecular diversity within genes is responsible amongst others, of disease resistance or susceptibility or for that matter drug response. Pharmacogenomics is ...
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[Fakultas Farmasi Universitas Indonesia, Universitas Indonesia], 2005
pdf
Artikel Jurnal Universitas Indonesia Library
Pendrianto
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Insiden dan mortalitas dari colorectal cancer CRC terus meningkat Beberapa metode skrining CRC umumnya bersifat invasif dan tidak nyaman Single Nucleotide Polymorphism SNP dapat dimanfaatkan sebagai marker untuk skrining CRC dengan tingkat invasif yang rendah Penelitian ini bertujuan untuk memvalidasi asosiasi antara SNP ldquo X rdquo dengan kerentanan terhadap CRC sporadik Desain penelitian menggunakan studi potong lintang Jumlah sampel dan daya uji pada kelompok CRC sporadik dan kontrol ditentukan dengan menggunakan Epi Info versi 3 ...
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Depok: Universitas Indonesia, 2012
T-Pdf
UI - Tesis Membership Universitas Indonesia Library
Weinheim: Wiley-VCH, 2009
615.7 EPI
Buku Teks Universitas Indonesia Library
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Fueled by the expertise of a team of international specialist authors, this first reference on the booming topic covers everything a drug researcher needs to know about targeting epigenetic mechanisms of disease. The first part of the book surveys current methodologies for finding and validating drug candidates that act via epigenetic mechanisms. The second part systematically surveys known and suspected drug targets within the epigenetic machinery, including the discovery and development of vorinostat, the first ...
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Weinheim: Wiley-VCH, 2009
e20393916
eBooks Universitas Indonesia Library
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Explains the identification of molecular targets via cellular assays, reporter genes or transgenic models, as well as surveying recent advances in the synthesis, separation and analysis of drugs. A special section is devoted to molecular genetics methods. ...
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Weinheim: Wiley-VCH, 2003
e20394257
eBooks Universitas Indonesia Library
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This book discuss early characterization of toxicity and efficacy would significantly impact the overall productivity of pharmaceutical R&D and reduce drug candidate attrition and failure. By describing the available platforms and weighing their relative advantages and disadvantages and including microarray data analysis. ...
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Hoboken, New Jersey: John Wiley & Sons, 2009
e20393938
eBooks Universitas Indonesia Library