Ditemukan 10 dokumen yang sesuai dengan query
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Latar belakang: Penelitian ini bertujuan untuk menilai akurasi penentuan dosis warfarin berdasarkan genotip VKORC1 dan CYP2C9 pada populasi China.
Metode: Sebanyak 37 pasien diambil sampel darah. Dilakukan perbandingan antara dosis warfarin yang didapat dari genotip (merujuk pada www.warfarindosing.org) dengan dosis terapi kadar INR 2,0 sampai 3,0.
Hasil: Majoritas penduduk China pada studi ini memiliki genotip VKORC1 AA homozigot (89,2%), jarang ditemukan penduduk dengan VKORC1 AG heterozigot, dan tidak ditemukan pasien dengan GG homozigot. Untuk genotip CYP2C9, hampir ...
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[Fakultas Kedokteran Universitas Indonesia, The First Affiliated Hospital of Soochow University, China. Department of Cardiovascular Diseases], 2012
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Artikel Jurnal Universitas Indonesia Library
Wu, Rongling
Boca Raton: CRC Press, Taylor & Francis Group, 2009
615.7 WU s
Buku Teks Universitas Indonesia Library
Weinheim: Wiley-VCH, 2009
615.7 EPI
Buku Teks Universitas Indonesia Library
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Fueled by the expertise of a team of international specialist authors, this first reference on the booming topic covers everything a drug researcher needs to know about targeting epigenetic mechanisms of disease. The first part of the book surveys current methodologies for finding and validating drug candidates that act via epigenetic mechanisms. The second part systematically surveys known and suspected drug targets within the epigenetic machinery, including the discovery and development of vorinostat, the first ...
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Weinheim: Wiley-VCH, 2009
e20393916
eBooks Universitas Indonesia Library
Amsterdam: Elsevier, 2012
615.7 THE
Buku Teks SO Universitas Indonesia Library
Boca Raton: CRC Pres/Taylor & Francis Group, 2009
615.7 GEN
Buku Teks Universitas Indonesia Library
Dickenson, Jhon P.
Chichester, West Sussex: Wiley-Blackwell, 2013
615.19 MOL
Buku Teks Universitas Indonesia Library
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Chemogenomics brings together the most powerful concepts in modern chemistry and biology, linking combinatorial chemistry with genomics and proteomics.
This first reference devoted to the topic covers all stages of the early drug discovery process, from target selection to compound library and lead design.
With the combined expertise of 20 research groups from academia and leading pharmaceutical companies, this is a must-have for every drug developer and medicinal chemist applying the powerful methods of chemogenomics ...
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Weinheim: Wiley-VCH Verlag, 2004
e20376579
eBooks Universitas Indonesia Library
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This book discuss early characterization of toxicity and efficacy would significantly impact the overall productivity of pharmaceutical R&D and reduce drug candidate attrition and failure. By describing the available platforms and weighing their relative advantages and disadvantages and including microarray data analysis. ...
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Hoboken, New Jersey: John Wiley & Sons, 2009
e20393938
eBooks Universitas Indonesia Library
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Molecular pathology offers tools and techniques that can greatly enhance the drug discovery and development process, helping to make the promises of personalized medicine a reality. Molecular Pathology in Drug Discovery and Development provides an unmatched guide to this cutting-edge discipline and its applications to pharmaceutical science.
With contributions from leading lights in drug discovery, drug development, and molecular pathology balanced by a consistent editorial approach, this reference offers both an overview of molecular pathology and ...
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Hoboken, New Jersey: John Wiley & Sons, 2009
e20394350
eBooks Universitas Indonesia Library
