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"Minyak olahan tradisional merupakan obat tradisional yang digunakan untuk mengobati berbagai penyakit kulit. Minyak mi adalah hasil penyarian beberapa bahan tanaman yang sebagian besar mengandung fenol, tanin dan saponin. Penelitian dilakukan tmtuk mengetahui efek penyembuhan minyak olahan tradisional dan bentuk sediaan krimnya dengan konsentrasi minyak 30% terhadap luka terbuka pada tikus putih. Pada penelitian mi digunakan 5 kelompok tikus putih betina galur Wistar yang dilukai dengan cara menggunting kulit pada bagian punggung sampai lapisan dermis dan jaringan yang terikat di dalamnya, berbentuk lingkaran dengan diameter 2 cm. Kelompok uji adalah tikus yang diberi minyak olahan tradisional dan krimnya, kelompok pembanding diberi asam salisilat 1% clan minyak kelapa, serta kelopmok kontrol tanpa pemberian bahan obat. Masing-masing kelompokterdiri dan 8 ekor tikus dan perlakuan dilakukan setiap han. Pengamatan dilakukan dengan mengukur diameter luka secara melintang, membujur dan pada 2 diagonal setiap hari mulai han ke-0 (hari pembuatan luka) sampai han ke-10. Hasil percobaan menunjukkan minyak olahan tradisional clan knimnya memberikan efek yang sangat bermakna terhadap penyembuhan luka terbuka pada tikus putih. Minyak olahan tradisional menghasilkan bekas luka yang lebih baik disertai pertumbuhan rambut yang lebih banyak dibandingkan dengan sediaan knimnya.

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This traditional processed oil is a traditional medicine that is used to cure some kind of skin diseases. This oil is extracted from plants that mostly contains phenolic, tannin and saponine compounds. This research was done to study the vulnerary effect of the traditional processed oil and the cream which contained 30% oil on open wounded albino rats. Five groups of female albino rats, Wistar strain, were excised through the dermis and adherent tissues on the dorsal region, in circular form with 2 cm diameter. The tested group consisted rats that had been given the traditional processed oil and its cream, a comparing group was given 1% salicylic acid and coconut oil, another control group without any medicine. Each group contained 8 rats, and the treatment was done once a day. Longitudinal, transverse and 2 diagonal average diameter were measured everyday from day-U until day- 10. The result showed that the traditional processed oil and its cream gave a very significant vulnerary effect of an open wound in albino rats. The traditional processed oil gave a less scar with more hair growth than its cream"

"ABSTRAKSelulit sudah lama dikenal sebagai sejenis kegemukan yang terjadi pada jutaanwanita di seluruh dunia dan berakibat pada penurunan nilai estetik. Berbagaimacam media banyak membahas mengenai penyakit ini beserta dengan berbagaimetode dan prosedur terapinya yang meliputi bedah, farmakologi, fitoterapi,homeopati, elektromedis, kosmetik, atau mesoterapi fisiologi. Namun semuanyaitu memerlukan biaya yang cukup tinggi sehingga hanya tersedia bagi merekayang mampu membelinya. Penelitian ini bertujuan untuk mengetahui pengaruhsediaan krim campuran minyak nilam (Pogostemon cablin.L), minyak melati(Jasminum sambac.L), dan minyak jahe merah (Zingiber officinale var rubrum)untuk mengatasi selulit. Minyak nilam, minyak melati, dan minyak jahe merahdibuat menjadi sediaan krim dengan konsentrasi masing-masing minyak 1.5%. Ujistabilitas fisik sediaan krim uji dilakukan selama 12 minggu dan uji keamanankepada relawan menggunakan metode uji tempel. Uji manfaat dilakukan selama28 hari pada area paha sebelah kanan. Sediaan krim uji menunjukkan kestabilanselama 12 minggu dan hasil uji keamanan ada sedikit menimbulkan iritasi pada 1orang dari total responden 46 orang. Hasil uji manfaat diukur denganmenggunakan parameter fotografi, pengukuran lingkar paha, cutometer, dancorneometer menunjukkan sediaan krim mampu menurunkan derajat selulit. Krimuji terbukti memberikan hasil yang lebih signifikan dibandingkan dengan krimplasebo, yaitu pada pemakaian krim selama 28 hari dan hasil statistikmenunjukkan ada perbedaan bermakna (p < 0,05).

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ABSTRACTCellulite has been known as kind of obesity that occured in millions of womenaround the world and resulted in decreasing aesthetic value. Various kinds ofmedia talked much about this disease along with the methods and proceduresincluding surgical therapy, pharmacology, phytotherapy, homeopathy,electromedical, cosmetics, or mesotherapy physiology. But all of them are quitehigh in cost, so they are only available to those who can afford them. The purposeof this study is to determine the effect of the cream mixture preparation ofpatchouli oil (Pogostemon cablin.L), jasmine oil (Jasminum sambac.L), and redginger oil (Zingiber officinale var rubrum) to cure cellulite. Patchouli oil, jasmineoil, and red ginger oil is mixed into a cream preparation with each concentrationcontains 1.5%. The physical stability of test cream dosage was conducted fromover 12 weeks and the safety test was conducted to 46 volunteers on the rightthigh using patch test. The test was done in 28 days at the right thigh. Preparationcream showed stability for 12 weeks and there is 1 out of 46 people that hadirritation while safety testing were being tested. The benefit results which aremeasured by using photographic parameters, measurement of thighcircumference, cutometer, and corneometer showed that the cream preparation iscapable of lowering the degree of cellulite. The mixture cream is proved to bemore significant in test results compared to placebo cream for 28 days therapy(P<0.05)."

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