Ditemukan 7 dokumen yang sesuai dengan query
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This handbook is the practical aspects of this novel method. It provides a complete overview of the field and progresses from general considerations to real life scenarios in drug discovery research.
Starting with an introductory historical overview, the authors move on to discuss ligand-based approaches, including 3D pharmacophores and 4D QSAR, as well as the concept and application of pseudoreceptors. The next section on structure-based approaches includes pharmcophores from ligand-protein complexes, FLIP and 3D protein-ligand binding ...
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Weinheim, Germany: Wiley-VCH, 2006
e20395917
eBooks Universitas Indonesia Library
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This first systematic summary of the impact of fragment-based approaches on the drug development process provides essential information that was previously unavailable. Adopting a practice-oriented approach, this represents a book by professionals for professionals, tailor-made for drug developers in the pharma and biotech sector who need to keep up-to-date on the latest technologies and strategies in pharmaceutical ligand design. The book is clearly divided into three sections on ligand design, spectroscopic techniques, and screening and ...
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Weinheim, Germany: Wiley-VCH, 2006
e20395918
eBooks Universitas Indonesia Library
Chibale, Kelly, editor
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This book critically reviews the current status of drug discovery research and development in Africa, for diseases that are a major threat to the health of people living in Africa. It explores how the use of natural products and traditional medicines can benefit from conventional drug discovery approaches, and proposes solutions to current technological, infrastructural, human resources, and economic challenges, which are presented when attempting to engage in full-scale drug discovery. Topics addressed are varied, ...
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Berlin: Springer, 2012
e20405843
eBooks Universitas Indonesia Library
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There are books that talk about drug design tools, algorithms, and math- ematical functions, and books that give some results showing that one compound worked better than another for inhibiting a particular enzyme. However, these books spend surprisingly little time discussing the process that the chemist goes through to actually design a new drug molecule. This book is oriented around the way that computational techniques are utilized in the drug design process ...
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Hoboken, New Jersey: John Wiley & Sons, 2009
e20376698
eBooks Universitas Indonesia Library
Storz, Ulrich
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This new volume in the series focuses on the particular IP issues of therapeutics, vaccines and molecular diagnostics. The first chapter concentrates on basics principles for protecting antibody compounds. Additional ways to create follow-up protection for antibody therapeutics are also discussed. The second chapter gives an overview of the patent landscape in molecular diagnostics, and discusses issues of patentability with respect to the different technologies and compounds used therein. The third chapter gives a broad ...
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Heidelberg : [Springer, ], 2012
e20417691
eBooks Universitas Indonesia Library
Hoboken, N.J. : Wiley-Interscience , 2017
R 615.19 HAN
Buku Referensi Universitas Indonesia Library
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The Drug Discovery Handbook gives professionals a tool to facilitate drug discovery by bringing together, for the first time in one resource, a compendium of methods and techniques that need to be considered when developing new drugs. This comprehensive, practical guide presents an explanation of the latest techniques and methods in drug discovery, including: Genomics, proteomics, high-throughput screening, and systems biology Summaries of how these techniques and methods are used to discover new central nervous ...
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Hoboken, N.J. : Wiley-Interscience , 2005
R 615.19 DRU
Buku Referensi Universitas Indonesia Library
