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"[Sepanjang 1.200 km garis pantai Provinsi Kepulauan Bangka Belitung terdapat potensi ekonomi yang meliputi perikanan dan wisata bahari. Namun di sisi lain, kemiskinan justru terjadi di wilayah perdesaan yang didominasi oleh desa pesisir. Padahal disitulah letak sumberdaya kelautan dan perikanan berada. Penelitian ini bertujuan untuk mengidentifikasi sektor prioritas dari aktivitas ekonomi yang terkait dengan sektor kelautan dan memproyeksikan estimasi investasi bagi pengelolaan sektor kelautan di Provinsi Kepulauan Bangka Belitung. Analisis Input Output digunakan untuk menentukan aktivitas ekonomi yang terkait di dalamnya. Dengan pendekatan ICOR (Incremental Capital Output Ratio) diproyeksikan estimasi kebutuhan investasi selama kurun waktu 2015-2017. Hasil penelitian menunjukkan bahwa sektor prioritas dikembangkan adalah wisata bahari; perikanan budidaya; industri pengolahan dan pengawetan ikan dan hasil biota air lainnya; jasa kelautan; dan bangunan kelautan . Nilai ICOR Kelautan Provinsi Kepulauan Bangka Belitung adalah 2.93, lebih efisien dibandingkan sektor kelautan secara nasional.;Bangka Belitung Province has 1,200 km coastline with big potential economic including fisheries and marine tourism. Otherwise, poverty has occurred in rural areas with dominated by coastal villages. While therein lies the marine and fisheries resources. This study aims to identify the priority sectors of economic activity associated with the marine sector and project investment estimate for the management of the marine sector in Bangka Belitung Province. Input Output Analysis is used to determine the priority of economic activity. With the approach of ICOR (Incremental Capital Output Ratio) projected of investment for 2015-2017 period. The results showed the priority sectors to be developed are marine tourism; aquaculture; fish processing; marine services; and marine building. ICOR for Marine development of Bangka Belitung Province is 2.93. It is more efficient than the national marine sector, Bangka Belitung Province has 1,200 km coastline with big potential economic including fisheries and marine tourism. Otherwise, poverty has occurred in rural areas with dominated by coastal villages. While therein lies the marine and fisheries resources. This study aims to identify the priority sectors of economic activity associated with the marine sector and project investment estimate for the management of the marine sector in Bangka Belitung Province. Input Output Analysis is used to determine the priority of economic activity. With the approach of ICOR (Incremental Capital Output Ratio) projected of investment for 2015-2017 period. The results showed the priority sectors to be developed are marine tourism; aquaculture; fish processing; marine services; and marine building. ICOR for Marine development of Bangka Belitung Province is 2.93. It is more efficient than the national marine sector]"

"Marine-derived fungi have proven to be a rich source of cytotoxic compounds for the development of new anti cancer drugs. The aims of this research were to: 1) screen cytotoxic activity of marine fungi from Indonesian waters, 2) indentify marine fungus that produced thatproduced the most active cytotoxic compound and 3) investigate inhibition concentration 50 (IC50) value of cytotoxic compound. The fungi were isolated from marine organism collected fromWakatobi Marine National Park-South East Sulawesi, Binuangeun Beach-Banten, Manado watersNorth Sulawesi and Kepulauan Seribu Marine National Park-Jakarta. Liquid cultures of the fungiwere carried out in Malt Extract Broth and Soluble Starch Soytone medium for 4 weeks at 27?28oC without shaking. Molecular identification of fungus was conducted through PCR amplificatin usingprimers of ITS1 and ITS4 primer. Cytotoxic activity of the extract was tested by using MTT (3-(4.4-dimethylthiazol-2-yl)-2.5-diphenyl-tetrazolium bromide) method. The MTT test showed that MFW39strain exhibited the strongest cytotoxic activity. Molecular identification revealed that MFW39 marine fungus was similar to Emericella nidulans with precent identity of 99%. Mycelium and broth extract of MFW39 fungus inhibited the growth of T47D cell with IC 50 values of 21.9 and 169.3 µg/mL, respectively. Further research will be focus on to the strain of MFW39 marine fungi."