Ditemukan 1 dokumen yang sesuai dengan query
Zhang, Xin
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This dissertation comprehensively demonstrates how two universally conserved guanosine triphosphatases in the signal recognition particle and its membrane receptor maintain the efficiency and fidelity of the co-translational protein targeting process essential to all cells. A series of quantitative experiments reveal that the highly ordered and coordinated conformational states of the machinery are the key to their regulatory function. This dissertation also offers a mechanistic view of another fascinating system in which multistate protein machinery closely ...
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New York: Springer, 2012
e20405941
eBooks Universitas Indonesia Library
