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Hasil Pencarian

Ditemukan 4 dokumen yang sesuai dengan query
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Gerie Amarendra
"Latar Belakang : Pankreatitis pasca ERCP adalah komplikasi tersering dan menyebabkan peningkatan morbiditas dan mortalitas. Hidrasi agresif sebagai terapi pencegahan pankreatitis belum diteliti lebih lanjut.
Tujuan : Mengetahui perbandingan efektivitas pencegahan pankreatitis pasca ERCP antara hidrasi agresif dengan hidrasi standar.
Metode : Uji Klinis Acak tersamar ganda, satu sentral penelitian di Pusat Endoskopi Saluran Cerna (PESC) RS Cipto Mangunkusumo pada pasien usia antara 18-60 tahun yang menjalani tindakan ERCP periode Agustus-Oktober 2018. Randomisasi manual, Teknik sampling konsekutif dilakukan untuk mengalokasikan kelompok hidrasi agresif dan hidrasi standar. Pankreatitis ditegakkan dengan kriteria Atlanta.
Hasil :  Didapatkan 92 pasien yang dirandomisasi kedalam dua kelompok. Didapatkan nilai Control Event Rate (CER) sebesar 15,2%, Experiment Event Rate (EER) sebesar 4,3% Absolute Risk Reduction (ARR) 10,9% Relative Risk (RR) 0,28 Relative Risk Reduction (RRR) 71,7% Number Needed to Treat (NNT) 9.  Tidak didapatkan efek samping pada kedua kelompok. Hidrasi agresif lebih efektif dalam mencegah pankreatitis pasca ERCP walaupun secara statistik tidak bermakna.  

Pancreatitis post ERCP is a common complication and increased morbidity and mortality. Aggressive hydration as prevention of post ERCP pancreatitis has not been fully research.
Aims : To compare effectivity between aggressive hydration and standard hydration in preventing pancreatitis post ERCP.
Design and Methods : A double blind randomized clinical trial in one center at gastrointestinal endoscopy center RSCM was conducted on patients aged between 18-60 years old that had endoscopic retrograde cholangiopancreatography in the period from August to October 2018. Consecutive manual randomization was performed to allocate aggressive hydration and standard hydration. Pancreatitis diagnosed using Atlanta criteria.
Results : Two groups with total 92 subject was randomized equally. Analyzed resulted  Control Event Rate (CER) 15,2%, Experiment Event Rate (EER) 4,3%, Absolute Risk Reduction (ARR) 10,9%, Relative Risk (RR) 0,28, Relative Risk Reduction (RRR) 71,7%, Number Needed to Treat (NNT) 9.  No side effect reported in this trial. Aggressive hydration more effective in perventing post ERCP pancreatitis although statistically not significant.  
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Depok: Fakultas Kedokteran Universitas Indonesia, 2019
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UI - Tesis Membership  Universitas Indonesia Library
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Kartika Hajarani
"ABSTRAK
Latar belakang:Bayi laringomalasia primer memiliki komorbiditas yang tinggi akibat silent aspiration. Hingga saat ini, belum diketahui prevalensi disfagia dan data mengenai gambaran fungsi menelan bayi laringomalasia primer. Tujuan penelitian: Mengetahuiprevalensi disfagia dan gambaran fungsi menelanpada bayi laringomalasia primersertamengetahui kesesuaian antara SEES dan FEES.Metode: Penelitiancross-sectional yang bersifat deskriptifdan analitik komparatif terhadap 34subjek bayi laringomalasia primersecara konsekutif di RS Dr. Cipto Mangunkusumoperiode Januari-Maret 2020. Hasil:Prevalensi disfagiapada bayi laringomalasiaprimersebanyak 9 dari 34 subjek (26,5%). Gejala disfagia pada bayi< 6 bulan tersering adalah regurgitasi dan apneasaat menyusu (5/6), sedangkan pada bayi>6 bulan adalah terdengar banyak lendir di tenggorok (3/3). Komorbid terbanyak adalah kelainan genetikdan PRGE(3/9). Komplikasi terseringadalah pneumonia aspirasi (6/9). Pada pemeriksaan awal FEES, kontrol postural terganggu(7/9) merupakantanda yang paling sering ditemukan. Pada pemeriksaan FEES, preswallowing leakagedidapatkan pada konsistensi puree, tim saring, dan tim kasar. Pada pemeriksaan SEES dan FEES, residu, penetrasi,dan aspirasipalingbanyak didapatkan pada konsistensi susu. Silent aspirationdidapatkan pada4 dari 9subjek dengan disfagia. Pemeriksaan SEES memiliki kesesuaian dengan FEES berdasarkanuji McNemarpadaparameter ada tidaknya penetrasi, residu, dan aspirasi.Kesimpulan:Prevalensi disfagia pada bayi laringomalasia primersebanyak 9 dari 34 subjek(26,5%), penetrasi dan aspirasi didapatkan pada konsistensi air dan susuterutama pada bayi< 6 bulan, dan SEES memiliki kesesuaian dengan FEESdalam menilai fungsi menelanberdasarkan parameter ada tidaknya residu, penetrasi, dan aspirasi.

Background:Silent aspiration is oftenunrecognized comorbidity in infants with congenital laryngomalacia with serious medical consequence. However, prevalence of dysphagia and characteristic of dysphagia ininfants with congenital laryngomalacia is still unknown. Aim: To find the prevalence and the overview of swallow function in infants with congenital laryngomalacia and also to know the conformity between SEES and FEES in assessing swallow function. Methods:This is a descriptive cross-sectional and comparative analytic study involving 34 infants with congenital laryngomalacia who came consecutivelytoDr. Cipto Mangunkusumo Hospitalon January-March 2019. Results: The prevalence of dysphagia was 9 out of 34 subjects (26,5%).Dysphagia symptom in infants<6 months was regurgitation and apneawhile bottle/breast feeding (5/6). Meanwhile, in infants>6 monthswaswet sounding voice (3/3). The comorbidities found mostly were geneticanomaly and GERD(3/9). The complication mostly was aspiration pneumonia (6/9). In pre-FESS examination, poor postural controlwas dominant(7/9). In FEES examination, preswallowingleakagewas found in puree, soft steam porridge, and rough steam porridge. In FEES and SEES examination, residue, penetration, and aspirationwas mostly found inthick liquid. Silent aspiration was found in 4 out of 9subjects with dysphagia. SEES has a conformity to FEES based on McNemar test in the presence of residue, penetration, and aspiration. Conclusion: The prevalence of dysphagia in infants with congenital laryngomalaciawas9 out of 34 subjects(26,5%). In FEES examination, penetration,and aspiration were found mostly in thin liquid, <6months of age predominantly.SEES has a conformity to FEES based on presence of residue, penetration, and aspiration in assessing swallow function."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2020
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UI - Tugas Akhir  Universitas Indonesia Library
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Akahoshi, Kazuya
"Endoscopic ultrasonography (EUS) has evolved from an obscure method of investigation in the 1980s to a distinct endoscopy subspecialty with interventional and therapeutic capabilities. The art of interpreting EUS images is a skill every endoscopist needs to master. This book helps to meet that need as it is concise, simple to read, and amply illustrated, and describes the technique in a step-by-step manner. Many high-resolution EUS images of diseases are included, and literature reviews are kept short and concise while separate discussions and illustrations are devoted to radial and linear techniques. The book can be used as a reference handbook in the endoscopy room, yet contains all of the relevant information required to perform EUS, interpret images, and reach a diagnosis. Important pathological conditions are thoroughly discussed using representative EUS images, pointing out salient differentiating features, and relevant literature reviews are included. The section on interventional EUS deals with advanced interventional or therapeutic procedures, and potential complications and methods to avoid them are discussed. "
Tokyo: Springer, 2012
e20426043
eBooks  Universitas Indonesia Library
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Abdul Gaffar Hamzah
"Latar Belakang : Tingkat akurasi EUS FNA dalam diagnosis lesi pankreas diduga dipengaruhi oleh berbagai macam faktor. Penelitian mengenai faktor yang mempengaruhi keberhasilan EUS FNA belum pernah dilakukan di Indonesia. Penelitian ini dilakukan untuk mengetahui faktor-faktor yang mempengaruhi keberhasilan EUS FNA untuk diagnosis lesi pankreas pada populasi Indonesia.
Metode : Penelitian ini merupakan studi potong lintang dari data rekam medis pada januari 2012-Juli 2022 atau total seluruh subjek yang dilakukan EUS FNA karena lesi pankreas di PESC RSCM. Pasien dengan data tidak lengkap dan lesi peripankreas tidak diikutkan. Karakteristik dasar subjek penelitian ditampilkan dalam bentuk tabel. Analisis bivariat menggunakan uji chi square dilakukan dengan masing-masing variabel bebas terhadap keberhasilan diagnostik EUS FNA untuk menghitung nilai odds ratio (OR). Variabel dengan nilai p< 0,25 pada analisa bivariat dimasukkan ke analisa multivariat dengan regresi logistik.
Hasil : Sebanyak 201 pasien dengan lesi pankreas yang menjalani pemeriksaan EUS FNA diikutkan dalam penelitian. Angka keberhasilan diagnostik EUS FNA pada lesi pankreas adalah sebesar 77,11%. Ukuran lesi ³3 cm diasoasikan dengan peningkatan keberhasilan diagnosis EUS FNA berdasarkan analisis bivariat (OR 2,46; IK95 1,25-4,86; p= 0,008). Analisis multivariat menunjukan bahwa ukuran lesi ³3 cm (OR 18,95; IK95 4,77-75,29; p = 0,000),  lokasi lesi di korpus (OR 2.82; IK95 1.03-7.77; p= 0,04) dan ukuran jarum 22G (OR 7.49; IK95 1.87-29.97; p= 0.004) diasoasikan dengan peningkatan keberhasilan diagnosis. 
Kesimpulan : Ukuran lesi, lokasi lesi dan ukuran jarum, merupakan faktor yang mempengaruhi keberhasilan diagnostik EUS FNA pada lesi pankreas.

Background: Diagnostic accuracy of EUS FNA in diagnosing pancreatic lesion are affected by several factors. Clinical study regarding these factors had not been done in Indonesia. This study aims to study factors affecting the diagnostic yield of EUS FNA in diagnosing pancreatic lesion in Indonesian population. 
Method: This study is a cross-sectional study of medical record data in January 2012-July 2022 or a total of all subjects who underwent EUS FNA due to pancreatic lesions at PESC RSCM. Patient with incomplete data and peripacreatic lesion was excluded. Clinical characteristics of sample is presented in a table. Bivariat analysis was conducted with chi square test between independent factors and diagnostic success of EUS FNA to obtained the odds ratio (OR). Factors with p-value above 0,25 are included for multivariat analysis using logistic regression.  
Result: A total of 201 patients underwent EUS FNA was included in this study. Success rate of diagnosing pancreatic lesion using EUS FNA was 77,11%. Lesion size ³3 cm increased the odds for diagnostic success based on bivariat analysis (OR 2,46; 95% CI 1,25-4,86; p = 0,008). Multivariate analysis showed that the lesion size ³ 3 cm (OR 18.95; CI95 4.77-75.29; p = 0.000), the location of the lesion in the corpus (OR 2.82; CI95 1.03-7.77; p = 0.04) and needle size 22G (OR 7.49; CI95 1.87-29.97; p= 0.004) was associated with an increase in diagnostic yield.
Conclusion: The size of the lesion, the location of the lesion and the size of the needle, are factors that influence the diagnostic yield of EUS FNA in pancreatic lesions
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Jakarta: Fakultas Kedokteran Universitas Indonesia, 2022
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UI - Tugas Akhir  Universitas Indonesia Library