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"High mortality in Indonesia, caused by acute coronary syndrome, has reached 26 %. In 10 years, National housing health survey or Survei Kesehatan Rumah Tangga Nasional ( SKRTN), under health departement of Republic of Indonesia, stated mortality which is caused by acute coronary syndrome has increased enourmously. It can be avoided by doing early acute coronary syndrome detection like ECG recording. Anyway, some those patients rarely do ECG recording because of expenses and time. By using Blutooth feature on PDA (Personal Digital Assistant) or a Bluetooth dongle on computer, a Telecardiology can be done anywhere and anytime so that coronary syndrome can be detected earlier by medics. Telecardiology research used a microcontroler, a computer and a PDA to record ECG signals. ECG recording is taken in real-time then stored in computer or PDA data base. To detec QRS waves in ECG signals, PanTompkins were used."

"Telah dibuat sistem pemantauan aktivitas jantung dan fisik manusia dengan menggunakan elektrokardiograf tiga lead dan sebuah sensor akselerometer 3-sumbu MMA7260Q yang diaplikasikan sebagai sistem perhitungan konsumsi energi dan pemantau kecepatan gerak. Dengan menggunakan sensor elektrode penulis merekam biopotensial yang dihasilkan oleh otot-otot jantung kemudian mengakuisisi data ini dengan menggunakan rangkaian elektrokardiograf dimana didalamnya terdapat penguat bertahap sebesar 4 kali, 101 kali, dan 5 kali. Untuk menghilangkan noise dirancang pula filter 0,5-100 Hz. Pada keluaran sinyal dari akselerometer dilakukan filter high-pass 0,5 Hz, sehingga elektrokardiograf mampu membaca aktivitas jantung kemudian data analog aktivitas jantung didigitasi menggunakan ADC mikrokontroler 128l, demikian juga data percepatan tubuh manusia mengalami proses digitasi menggunakan ADC mikrokontroler. Kedua data ini disimpan ke dalam sebuah kartu memori. Data aktivitas jantung dan percepatan tubuh manusia kemudian diolah secara digital menggunakan program LabVIEW8.5. Penganalisaan data elektrokardiograf dilakukan dengan tujuan mendapatkan pola perbandingan tetap antara luasan, amplitudo, dan periode sinyal P Q R S dan T. Sedangkan pengolahan data percepatan langkah tubuh digunakan untuk menghitung konsumsi energi dan kecepatan gerak tubuh manusia. Perubahan pola sinyal elektrokardiograf dibandingkan dengan perhitungan konsumsi energi dan kecepatan aktivitas tubuh manusia. Sehingga didapatkan sebuah hubungan antara sinyal P Q R S dan T dengan konsumsi energi dan kecepatan aktivitas tubuh manusia.

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Monitoring system of heart activity and human physical have made using electrocardiograph three leads and an accelerometer censor 3-axis MMA7260Q which is applied as calculation system of energy consumption and monitoring moving acceleration. Using electrode censor, the writer recorded biopotential which resulted from heart muscle and then process data using electrocardiograph series which have stronger in stage 4x, 101x, and 5x. To reduce the noise, filter 0,5-100 Hz was designed. In output signal from accelerometer, filter high-pass 0,5 Hz installed that electrocardiograph be able reading heart activity and then the data analog of heart activity digitized using ADC microcontroller 128l, and so did the data acceleration of human body. Both of these data saved in a memory card. The data of heart activity and human body acceleration processed digitally using LabVIEW8.5 program. Analyzing electrocardiograph data was done in goal to find a ratio for area, amplitude, and signal period of P Q R S and T. Processing data of body step acceleration used for counting energy consumption and moving velocity of human body. Alteration of electrocardiograph signal was compared with result of calculation from energy consumption and velocity of human activity. So, writer got a correlation in P Q R S and T signal with energy consumption and velocity of human activity."

"Daun gambir (Uncaria gambir) mengandung katekin yang secara empiris dapat bersifat antihipertensi melalui mekanisme penghambatan Angiotensin Converting Enzyme (ACE) secara non-spesifik. Tekanan darah erat kaitannya dengan aktivitas jantung. Penggunaan daun gambir sebagai antihipertensi harus dipastikan keamanannya. Penelitian ini bertujuan untuk melihat pengaruh pemberian ekstrak etanol 70% daun gambir terhadap aktivitas listrik jantung pada tikus hipertensi. Tiga puluh enam tikus Sprague Dawley dibagi dalam enam kelompok yakni normal, negatif, atenolol dan tiga kelompok dosis. Induksi larutan NaCl (3,65 g/kg bb) diberikan pada setiap kelompok perlakuan, kecuali kelompok normal, secara per oral selama 14 hari. Pada hari ke-15 dilanjutkan pemberian sediaan uji berupa larutan CMC 0,5% (kontrol normal dan negatif), atenolol 13,5 mg/200 g bb, dan ekstrak daun gambir dengan dosis 200; 400; dan 800 mg/200 g bb hingga hari ke-28. Pengukuran aktivitas listrik jantung dilakukan pada hari ke-21 dan 28 dengan menggunakan elektrokardiogram CareWell®. Hasil analisis menunjukan bahwa pemberian ekstrak etanol 70% daun gambir dosis 800 mg/200 g bb selama 7 hari dapat menurunkan laju jantung, memperbesar tegangan T, memperpanjang interval PR dan memperpanjang interval QT. Sedangkan, pemberian dosis 800 mg/200 g bb selama 14 hari hanya menurunkan laju jantung dan memperpanjang interval PR. Penggunaan ekstrak daun gambir pada dosis 800 mg/200 g bb sebagai antihipertensi memerlukan pengawasan karena dapat mempengaruhi aktivitas listrik jantung.

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Gambir leaves (Uncaria gambir) contain catechin which empirically can be used as antihypertensive through its mechanism as non spesicific Angiotensin Converting Agent (ACE) inhibitor. Blood pressure is closely related to the heart activity. It is necessary to test the security of gambir leaves as antihypertensive against cardiovascular system.

This research aimed to know the effect of 70% ethanol extract of gambir leaves against heart electrical activity in hypertensive rats. Thirty male rats strain Sprague-Dawley were divided into six groups which used and administered orally with CMC liquid 0,5% (normal control), NaCl liquid 3,65 g/kg bw (negative control), atenolol, and three groups of gambir leaves extract. NaCl liquid as inducer was administered orally for 14 days, then on 15th day continued by giving the gambir leaves extract (200; 400; and 800 mg/200g bw), atenolol 13,5 mg/200g bw and CMC 0,5%. Heart electrical activity was measured on the day 21st and 28th using electrocardiogam CareWell®.

Result from analysis showed that giving 70% ethanol extract of gambir leaves dose 800 mg/200g bw for 7 days could decrease heart rate, increase T voltage, prolong PR and QT interval. While giving extract dose 800 mg/200g bw for 14 days only decrease heart rate and prolong PR interval. The use of gambir leaves extract dose 800 mg/200 g bw as antihypertensive should be supervised due its affect to heart electrical activity."