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Hasil Pencarian

Ditemukan 12 dokumen yang sesuai dengan query
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New York: Academic Press, 1983
615.7 QUA (1)
Buku Teks  Universitas Indonesia Library
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Stuper, Andrew J.
New York: John Wiley & Sons, 19779
621.015 STU c
Buku Teks  Universitas Indonesia Library
cover
Elly Zahara
" ABSTRAK Pengelolaan perbekalan farmasi sebagai suatu sistem memegang peranan yang cukup penting dalam meningkatkan pelayanan di rumah sakit, baik dilihat dari sudut kepentingan pasien maupun kepentingan rumah sakit sendiri. Perencanaan pengelolaan perbekalan farmasi perlu dibentuk dengan baik, karena penggunaan perbekalan farmasi di rumah sakit memerlukan biaya yang besar oleh karena itu perlu adanya sistem yang tepat dan koordinasi yang baik oleh instalasi farmasi dan unit-unit pemakai. Hasil penelitian menunjukkan bahwa pengelolaan perbekalan farmasi di RSUP H. Adam Malik ... "
Depok: Universitas Indonesia, 1997
T-Pdf
UI - Tesis Membership  Universitas Indonesia Library
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Doucet, Jean Pierre
" Summary: The quantitative structure-activity relationships (QSAR) continue to evolve quickly with an explosion of various tools and techniques. This book addresses the scope and limitations of different modeling techniques using case studies from pharmacology, toxicology, and ecotoxicology to demonstrate the utility of each techniqu ... "
Boca Raton: CRC Press, 2010
615.190 72 DOU t
Buku Teks  Universitas Indonesia Library
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" The only reference on current methods to generate pharmacokinetic and safety profiles of drug candidates, as well as how they must be balanced against one other for the best selection of candidates for further development. Following a brief introduction to the necessities of filtering and risk assessment of potential new drug molecules before actual drug development, the two equally important aspects of pharmacological (ADME) and safety (toxicity) profiling are covered in separate parts. The ADME ... "
Weinheim, Germany: Wiley-VCH, 2009
e20394190
eBooks  Universitas Indonesia Library
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Kamada, Rui
" This thesis presents the first report of the comprehensive and quantitative analysis of the effects of tumor-derived mutations on the tetrameric structure of tumor suppressor protein p53, which plays a central role in maintaining genomic integrity. Inactivation of p53 via mutation of its gene is a key step in tumorigenesis. Biophysical analyses revealed that the stability of the mutant peptides varied widely. Formation of a tetrameric structure is to be critical for protein–protein interactions, DNA ... "
Tokyo : Springer, 2012
e20406084
eBooks  Universitas Indonesia Library
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" This practice-oriented handbook surveys current knowledge on the prediction and prevention of adverse drug reactions related to off-target activity of small molecule drugs. It is unique in collating the current approaches into a single source, and includes several highly instructive case studies that may be used as guidelines on how to improve drug development projects. With its large section on ADME-related effects, this is key knowledge for every drug developer ... "
Weinheim, Germany: Wiley-Vch, 2008
e20375710
eBooks  Universitas Indonesia Library
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" Barrier, reservoir, target site, those are but some of the possible functions of biological lipid membranes in the complex interplay of drugs with the organism. A detailed knowledge of lipid membranes and of the various modes of drug-membrane interaction is therefore the prerequisite for a better understanding of drug action. Many of today's pharmaceuticals are amphiphilic or catamphiphilic, enabling them to interact with biological membranes. Crucial membrane properties are surveyed and techniques to elucidate drug-membrane ... "
Weinheim, Germany: Wiley-Vch Verlag, 2002
e20393901
eBooks  Universitas Indonesia Library
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" This first systematic overview for more than a decade is tailor-made for the medicinal chemist. All the chapters are written by experienced drug developers and include practical examples from real drug candidates. Following an introduction to global drug properties and their impact on drug research, screening and combinatorial chemistry libraries, this handbook demonstrates the best and fastest way to estimate those properties most relevant for the efficiency and pharmacokinetic performance of a drug molecule: lipophilicity,solubility, ... "
Weinheim, Germany: Wiley-VCH, 2008
e20395825
eBooks  Universitas Indonesia Library
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