Ditemukan 15 dokumen yang sesuai dengan query
Testa, Bernard
London: Academic Press, 1995
615.7 TES m
Buku Teks Universitas Indonesia Library
Gibson, G. Gordon
Jakarta: Penerbit Universitas Indonesia (UI-Press), 2006
574.133 GIB p
Buku Teks Universitas Indonesia Library
London: John Wiley & Sons, 1976
615.7 PRO I
Buku Teks Universitas Indonesia Library
Canada: Martin Dunitz, 2001
615.58 DRU
Buku Teks Universitas Indonesia Library
"
The medical benefits of a drug are not only dependent on its biological effect, but also on its "life cycle" within the organism, from its absorption into the blood, distribution to tissue until its eventual breakdown or excretion by the liver and kidneys.
Here, the authors, all of them employed at Pfizer in the discovery and development of new active substances, discuss the significant parameters and processes important for the absorption, distribution and retention of drug ...
"
Weinheim, Germany: Wiley-VCH, 2001
e20394494
eBooks Universitas Indonesia Library
Baltimore: Williams & Wilkins, 1977
615.7 DRU
Buku Teks Universitas Indonesia Library
Thomas, Gareth
Chichester: John Wiley, 2007
615.19 THO m
Buku Teks Universitas Indonesia Library
"
Many times drugs work fine when tested outside the body, but when they are tested in the body they fail. One of the major reasons a drug fails is that it cannot be absorb by the body in a way to have the effect it was intended to have. Permeability, solubility, dissolution, and charged state of ionizable molecules :
- Helps drug discovery professionals to eliminate poorly absorbable molecules
early in the drug discovery ...
"
Hoboken, New Jersey: John Wiley & Sons, 2003
e20375117
eBooks Universitas Indonesia Library
"
A valuable reference tool for professionals involved in the industry, Drug Metabolism in Pharmaceuticals covers new tools such as LC-MS and LC-MS-NMR along with experimental aspects of drug metabolism. This work fills a gap in the literature by covering the concepts and applications of pharmaceutical research, development, and assessment from the point of view of drug metabolism. By providing both a solid conceptual understanding of the drug metabolism system, and a well illustrated, detailed demonstration ...
"
Hoboken, New Jersey: John Wiley & Sons, 2009
e20385346
eBooks Universitas Indonesia Library
"
Many drugs and other xenobiotics (e.g., preservatives, insecticides, and plastifiers) contain hydrolyzable moieties such as ester or amide groups. In biological media, such foreign compounds are, therefore, important substrates for hydrolytic reactions catalyzed by hydrolases or proceeding non-enzymatically.
Despite their significance, until now, no book has been dedicated to hydrolysis and hydrolases in the metabolism of drugs and other xenobiotics. This work fills a gap in the literature and reviews metabolic reactions of hydrolysis and ...
"
Weinheim, Germany: Wiley-Vch, 2003
e20394191
eBooks Universitas Indonesia Library
