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Ditemukan 16 dokumen yang sesuai dengan query
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" Strategic planning is a critical subject, central to the success of any scientific and economical enterprise. Not only is the scientific knowledge of many persons needed, but also an assessment of what may occur in the future - which approach may be competitive, which option can be achieved, and how can this be accomplished. With a focus on the various ethical obligations to patients, animals and the environment, this book offers hands-on help on how to ... "
Weinheim: VCH, 1996
e20395200
eBooks  Universitas Indonesia Library
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Kazmierski, Wieslaw M.
" This book focuses on new small molecule approaches to combat viral infections. The chapters describe the discovery and development from bench through the clinic of relatively recently-approved antiviral drugs and compounds in advanced clinical development. Organized by a virus (such as HIV, HCV, RSV, influenza, HBV and CMV) and written by top academic and industrial authorities in the field, the book provides a unique opportunity to study, understand and apply discovery and development principles and ... "
New Jersey: John Wiley & Sons, 2011
e20375714
eBooks  Universitas Indonesia Library
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" This book addresses all the current, up-to-date developments in this scientific discipline. Liver is the chief metabolizing site in the body, and thus, it is a major target organ for drug and chemical toxicity. Therefore, hepatotoxicity is an important endpoint in the safety evaluation of drugs and chemicals. Contributions from leading investigators in hepatotoxicity research address current developments in this scientific discipline and discuss use of current cutting edge technology such as microarrays in hepatotoxicity thus ... "
Chichester, West Sussex, England: John Wiley & Sons, 2007
e20395854
eBooks  Universitas Indonesia Library
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" Pharmacometrics is the science of interpreting and describing pharmacology in a quantitative fashion. The pharmaceutical industry is integrating pharmacometrics into its drug development program, but there is a lack of and need for experienced pharmacometricians since fewer and fewer academic programs exist to train them. Pharmacometrics : the science of quantitative pharmacology lays out the science of pharmacometrics and its application to drug development, evaluation, and patient pharmacotherapy, providing a comprehensive set of tools for ... "
Hoboken, New Jersey: John Wiley & Sons, 2007
e20395856
eBooks  Universitas Indonesia Library
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" This book the only comprehensive guide of its kind, this groundbreaking two-volume resource provides an overview of the entire sequence of operations involved in drug discovery and development from initial conceptualization to commercialization to clinicians and medical practitioners. Volume 2 : drug development delves into the nitty-gritty details of optimizing the synthetic route, drug manufacturing, outsourcing, and marketing-including drug coloring and delivery methods. Featuring contributions from a world-class team of experts, Drug discovery and development : - Features ... "
Hoboken, New Jersey: John Wiley & Sons, 2007
e20395858
eBooks  Universitas Indonesia Library
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" The essentials of drug metabolism vital to developing new therapeutic entities. Information on the metabolism and disposition of candidate drugs is a critical part of all aspects of the drug discovery and development process. Drug metabolism, as practiced in the pharmaceutical industry today, is a complex, multidisciplinary field that requires knowledge of sophisticated analytical technologies and expertise in mechanistic and kinetic enzymology, organic reaction mechanism, pharmacokinetic analysis, animal physiology, basic chemical toxicology, preclinical pharmacology, and molecular ... "
Hoboken, New Jersey: John Wiley & Sons, 2008
e20395867
eBooks  Universitas Indonesia Library
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" Backed by leading authorities, this is a professional guide to successful compound screening in pharmaceutical research and chemical biology, including the chemoinformatic tools needed for correct data evaluation. The authors discuss such factors as chemical genetics, binding, cell-based and biochemical assays, the efficient use of compound libraries and data mining using cell-based assay results ... "
Weinheim: Wiley-VCH, 2006
e20395921
eBooks  Universitas Indonesia Library
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" This book contains case studies of the discovery of erythromycin analogs (antibiotics), Tagamet, and Ultiva (remifentanil). Discusses the discovery of agents for the treatment and management of bacterial infections, Parkinson's disease, psoriasis, ulcers and stomach pain, atopic dermatitis, asthma, and cancer. Contains chapters on combinatorial chemistry, molecular biology-based drug discovery, genomics, and chemogenomics. The first volume of this set thoroughly describes conceptualizing a drug, creating a library of candidates for testing, screening those candidates for in ... "
Hoboken, New Jersey: Wiley-Interscience, 2006
e20395928
eBooks  Universitas Indonesia Library
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" This book discusses key statistical concepts that facilitate the inferential analysis of data collected from a group of individuals participating in a pharmaceutical clinical trial, the estimation of their clinical significance in the general population of individuals likely to be prescribed the drug if approved, and the related decision-making that occurs at both the public health level (by regulatory agencies when deciding whether or not to approve a new drug for marketing) and the individual ... "
New York: Springer, 2012
e20401564
eBooks  Universitas Indonesia Library
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