Ditemukan 11 dokumen yang sesuai dengan query
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This first overview of mass spectrometry-based pharmaceutical analysis is the key to improved high-throughput drug screening, rational drug design and analysis of multiple ligand-target interactions. The ready reference opens with a general introduction to the use of mass spectrometry in pharmaceutical screening, followed by a detailed description of recently developed analytical systems for use in the pharmaceutical laboratory.
Applications range from simple binding assays to complex screens of biological activity and systems containing multiple targets or ...
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Weinheim, Germany: Wiley-VCH, 2007
e20395818
eBooks Universitas Indonesia Library
Tsai, Tung-Hu, editor
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This book emphasizes the applications of microdialysis in different organs and tissues for pharmacokinetic and pharmacodynamic studies, covering the range of current clinical uses for microdialysis. Along with details of the basics of this analytical technique, topics in the book include applications for drug discovery, analytical consideration of samples, neurological disease investigations, sampling at different organs, diabetes evaluations, tumor response estimations and comparison of microdialysis ...
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New Jersey: John Wiley & Sons, 2011
e20375715
eBooks Universitas Indonesia Library
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This first systematic overview for more than a decade is tailor-made for the medicinal chemist. All the chapters are written by experienced drug developers and include practical examples from real drug candidates. Following an introduction to global drug properties and their impact on drug research, screening and combinatorial chemistry libraries, this handbook demonstrates the best and fastest way to estimate those properties most relevant for the efficiency and pharmacokinetic performance of a drug molecule: lipophilicity,solubility, ...
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Weinheim, Germany: Wiley-VCH, 2008
e20395825
eBooks Universitas Indonesia Library
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Pharmacometrics is the science of interpreting and describing pharmacology in a quantitative fashion. The pharmaceutical industry is integrating pharmacometrics into its drug development program, but there is a lack of and need for experienced pharmacometricians since fewer and fewer academic programs exist to train them. Pharmacometrics : the science of quantitative pharmacology lays out the science of pharmacometrics and its application to drug development, evaluation, and patient pharmacotherapy, providing a comprehensive set of tools for ...
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Hoboken, New Jersey: John Wiley & Sons, 2007
e20395856
eBooks Universitas Indonesia Library
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This book the only comprehensive guide of its kind, this groundbreaking two-volume resource provides an overview of the entire sequence of operations involved in drug discovery and development from initial conceptualization to commercialization to clinicians and medical practitioners.
Volume 2 : drug development delves into the nitty-gritty details of optimizing the synthetic route, drug manufacturing, outsourcing, and marketing-including drug coloring and delivery methods.
Featuring contributions from a world-class team of experts, Drug discovery and development :
- Features ...
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Hoboken, New Jersey: John Wiley & Sons, 2007
e20395858
eBooks Universitas Indonesia Library
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Post genomics drug discovery and research explores and discusses some of the most important topics in post-genomics life and biopharmaceutical sciences. It provides an introduction to the field, outlining examples of many techniques currently used, as well as those still under development, which are important for the research of biopharmaceutical discovery in the post-genomics era.
Integrates several developing and cutting-edge technologies and methods like bioinformatics, experimental therapeutics, and molecular recognition
Includes discussion on topics such as : ...
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Hoboken, New Jersey: John Wiley & Sons, 2007
e20395863
eBooks Universitas Indonesia Library
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This handbook emphasizes why solid-state issues are important, which approaches should be taken to avoid problems and exploit the opportunities offered by solid state properties in the pharmaceutical and agricultural industries ...
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Weinheim, Germany: Wiley-VCH, 2006
e20395873
eBooks Universitas Indonesia Library
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Backed by leading authorities, this is a professional guide to successful compound screening in pharmaceutical research and chemical biology, including the chemoinformatic tools needed for correct data evaluation. The authors discuss such factors as chemical genetics, binding, cell-based and biochemical assays, the efficient use of compound libraries and data mining using cell-based assay results ...
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Weinheim: Wiley-VCH, 2006
e20395921
eBooks Universitas Indonesia Library
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This book contains case studies of the discovery of erythromycin analogs (antibiotics), Tagamet, and Ultiva (remifentanil). Discusses the discovery of agents for the treatment and management of bacterial infections, Parkinson's disease, psoriasis, ulcers and stomach pain, atopic dermatitis, asthma, and cancer. Contains chapters on combinatorial chemistry, molecular biology-based drug discovery, genomics, and chemogenomics.
The first volume of this set thoroughly describes conceptualizing a drug, creating a library of candidates for testing, screening those candidates for in ...
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Hoboken, New Jersey: Wiley-Interscience, 2006
e20395928
eBooks Universitas Indonesia Library
Amsterdam: Elsevier/Academic Press, 2011
R 615.19 HAN
Buku Referensi Universitas Indonesia Library
