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Hasil Pencarian

Ditemukan 16 dokumen yang sesuai dengan query
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Rudi
"kanker yang tersisa saat oprasi atau sel kanker yang resisten terhadap obat kemoterapi atau radiasi. Penelitian ini dilakukan untuk menggali pengalaman pasien kanker pada saat mengalami kekambuhan. Metode penelitian studi kualitatif fenomenologi interpretatif. Sampel pasien kanker dewasa pria atau wanita yang mengalami kekambuhan. Hasil ditemukan dua tema dan beberapa subtema : 1) Reaksi saat kambuh (reaksi secara fisik dan reaksi secara psikologis), 2) Upaya yang dilakukan pasien untuk mengatasi kekambuhan kanker (upaya yang dilakukan secara non medis, upaya yang dilakukan secara medis, merubah gaya hidup, dan lebih mendekatkan diri kepada Tuhan). Simpulan pasien yang mengalami kekambuhan kanker timbul gejala secara fisik baik ditempat yang sama atau ditempat yang berbeda disertai dengan respon psikologis. Upaya yang dilakukan secara non medis dan medis, merubah gaya hidup dan melakukan pendekatan diri kepada Tuhan. Rekomendasi untuk penelitian selanjutnya adalah hasil penelitian ini dapat menjadi data untuk mengukur secara kuantitatif masalah dan kebutuhan yang diperlukan pasien kanker saat mengalami kekambuhan.

Reactions during relapse and various self-management at cancer recurrence. Recurrence can occur due to the presence of cancer cells left during surgery or cancer cells that are resistant to chemotherapy drugs or radiation. This study was conducted to explore the experiences of cancer patients at the time of relapse. The research method is a qualitative study of interpretive phenomenology. Samples of male or female adult cancer patients who experienced recurrence. The results found two themes and several sub-themes: 1) Reactions during relapse (physical reactions and psychological reactions), 2) Efforts made by patients to overcome cancer recurrence ( efforts made non-medically, efforts made medically, lifestyle changes , and draw closer to God). In conclusion, patients who experience cancer recurrence have physical symptoms either in the same place or in different places accompanied by psychological responses. Efforts are made non-medically and medically, changing lifestyles and approaching yourself to God. The recommendation for further research is that the results of this study can be used as data to quantitatively measure the problems and needs needed by cancer patients when experiencing a relaps"
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2022
T-pdf
UI - Tesis Membership  Universitas Indonesia Library
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Hesti Rahayu
"Tujuan: Penelitian bertujuan untuk menilai hubungan antara dukungan sosial, spiritualitas, dan stress terhadap beban keluarga dan kenyamanan pasien kanker. Metode: Desain penelitian yang digunakan adalah cross sectional dengan teknik purposive sampling, melibatkan 106 keluarga dan 106 pasien kanker. Penelitian ini menggunakan lima instrumen yaitu: Multimodal Scale of Perceived Social Support (MSPSS), Functional Assessment of Chronic Illness Therapy Spiritual Well-Being Scale (FACIT-sp), Perceived Stress Scale (PSS-10), Caregiver Reaction Assessment Scale (CRA), dan kuesioner kenyamanan pasien kanker. Hasil: Penelitian ini menunjukkan bahwa terdapat hubungan yang signifikan antara dukungan sosial dengan beban keluarga (p value 0.030), spiritualitas dengan beban keluarga (p value 0,000), dan stress dengan beban keluarga (p value 0.024). Stadium kanker tidak memiliki hubungan yang signifikan dengan kenyamanan pasien kanker (p value 0.080). Kesimpulan: Dukungan sosial, spiritualitas, dan stress berpengaruh terhadap beban keluarga. Diperlukan intervensi terkait dukungan sosial, spiritualitas, dan menagamen stress untuk menurunkan beban keluarga pasien kanker. 

To determine the relationship between social support, spirituality, and stress towards the family caregivers burden and patients comfort. Method: Cross sectional was used. Purposive sampling technique involving 106 family caregivers and 106 cancer patients. This study utilized five instruments: Multimodal Scale of Perceived Social Support (MSPSS), Functional Assessment of Chronic Illness Therapy Spiritual Well-Being Scale (FACIT-sp), Perceived Stress Scale (PSS-10), Caregiver Reaction Assessment Scale (CRA), and instrument for cancer patients comfort. Result: There was a significant relationship between social support and family caregiving burden (p value 0.030), spirituality and family caregiving burden (p value 0,000), stress and family caregiving burden (p value 0.024). There was no significant relationship  between cancer stage and patients comfort (p value 0.080). Conclusion: Social support, spirituality, and stress affect the family caregiving burden. It need intervention in social support, spirituality, and stress management to decrease the family caregiving burden."
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2019
T54156
UI - Tesis Membership  Universitas Indonesia Library
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Arza Rufli
"Kanker merupakan penyakit kronis yang menjadi salah satu penyebab kematian terbanyak di dunia. Pasien kanker umumnya memiliki kesadaran yang kurang tentang kanker dan layanan skrining, sehingga, pengambilan keputusan untuk melakukan pengobatan sering tertunda. Tujuan penelitian ini adalah mengeksplorasi pengalaman pasien kanker yang berkaitan dengan perilaku mencari bantuan kesehatan.  Penelitian ini menggunakan desain penelitian kualitatif deskriptif. Wawancara semi terstruktur dilakukan pada 10 orang dalam penelitian ini. Hasil penelitian ini memunculkan lima tema antara lain: 1) Keputusan menjalani pengobatan medis; 2) Keputusan menjalani pengobatan alternatif; 3)Hambatan dalam menjalani pengobatan medis; dan 4) Manfaat yang didapat dari pengobatan medis, dan 5) Manfaat yang didapat dari pengobatan alternatif daerah. Peran dari perawat onkologi maupun tenaga kesehatan  lainnya dibutuhkan untuk memahami pilihan pengobatan masing – masing pasien serta memberikan informasi yang tepat tentang pilihan pengobatan kanker yang tepat dan dibutuhkan oleh pasien kanker.  

Cancer is a chronic disease and one of the leading causes of death worldwide. Cancer patients generally have low awareness about cancer and screening services, leading to delayed decision-making for treatment. The aim of this study is to explore the experiences of cancer patients related to help-seeking behavior. This study uses a descriptive qualitative research design. Semi-structured interviews were conducted with 10 participants. The results of this study revealed five themes: 1) Decision to undergo medical treatment; 2) Decision to undergo alternative treatment; 3) Barriers to undergoing medical treatment; and 4) Benefits gained from medical treatment, and 5) Benefits gained from local alternative medical treatment. The role of oncology nurses and other healthcare professionals is crucial in understanding each patient's treatment choices and providing accurate information about the appropriate cancer treatment options needed by cancer patients."
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2004
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UI - Tesis Membership  Universitas Indonesia Library
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Fardi Fajrian Ihsana
"Sebagian besar pendekatan perawat dalam merawat pasiennya ditentukan oleh peran gender, sehingga masalah seperti kesetaraan dalam pemberian perawatan keperawatan spiritual menjadi sangat penting. Studi-studi yang ada belum secara menyeluruh memfokuskan perbedaan peran gender dalam asuhan keperawatan spiritual. Tujuan dari penelitian ini adalah untuk menyelidiki hubungan antara kompetensi dalam pemberian asuhan keperawatan spiritual oleh setiap perawat berdasarkan peran gender bagi pasien perawatan paliatif kanker di Rumah Sakit Kanker Dharmais, Jakarta. Penelitian ini menggunakan desain korelasional kuantitatif potong-lintang dengan 110 perawat sebagai partisipan melalui teknik quota sampling dengan Bem Sex Role Inventory-Short Form (BSRI) dan Spiritual Care Competence Scale (SCCS) sebagai instrumen penelitian untuk mengukur peran gender dan kompetensi asuhan keperawatan spiritual. Hasil analisis bivariat menunjukkan bahwa ada hubungan yang signifikan secara statistik antara feminitas (r = 0,530, p < 0,001) dan maskulinitas (r = 0,611, p < 0,001) dengan kompetensi asuhan keperawatan spiritual, serta adanya perbedaan dalam kompetensi asuhan keperawatan spiritual antara perawat dengan peran gender androgynous dan undifferentiated (p < 0,001). Rumah sakit atau fasilitas kesehatan yang memiliki perawatan paliatif bagi pasien kanker seharusnya mendorong perawat, terlepas dari jenis kelamin biologisnya, untuk mengekspresikan kedua peran gender karena berkorelasi positif dengan kompetensi asuhan keperawatan spiritual. Penelitian selanjutnya dapat mengeksplorasi lebih lanjut karakteristik masing-masing peran gender sehingga dapat ada bukti yang lebih definitif mengenai hubungan antara peran gender dan kompetensi perawatan keperawatan spiritual.

Every nurse regardless of their sociodemographic background must be competent in providing quality spiritual nursing care. As gender roles dictate much of nurses’ approach in caring for their patients, matters such as equality in the provision of spiritual nursing care becomes urgent. Existing studies have not focused thoroughly on the gender roles difference in spiritual nursing care. The aim of this study was to investigate the correlation between the competence of spiritual nursing care provision by each nurse by gender roles for cancer palliative care patients at Dharmais Cancer Hospital, Jakarta. This study used quantitative correlational cross-sectional design with 110 nurses as participants through quota sampling with Bem Sex Role Inventory-Short Form (BSRI) and Spiritual Care Competence Scale (SCCS) as the research instruments to measure gender roles and spiritual nursing care competence. Univariate analysis results showed that as much as 42,7% nurses had undifferentiated gender role followed by 39,1% nurses having androgynous gender role; while the median score of SCCS was 107, indicating high competence in spiritual nursing care. Bivariate analysis results showed that there were statistically significant correlations between femininity (r = 0,530, p < 0,001) and masculinity (r = 0,611, p < 0,001) with spiritual nursing care competence and that there was a difference in spiritual nursing care competence between nurses with androgynous and undifferentiated gender roles (p < 0,001). Existing hospitals or health facilities with palliative care for cancer patients should encourage nurses regardless of biological sex to express both gender roles as they correlate positively with spiritual nursing care competence. The next research can explore more regarding each characteristic in each gender role so that there can be more definitive evidence regarding the relationship between gender roles and spiritual nursing care competence."
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2024
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UI - Skripsi Membership  Universitas Indonesia Library
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Tuti Nuraini
"ABSTRAK
Pasien kanker payudara di Indonesia sering mengalami ketidaknyamanan fisik dan psikologis, namun perawat belum dapat secara optimal membantunya. Hal ini terjadi antara lain karena sulitnya mengkaji kondisi/tingkat kenyamanan dan mengidentifikasi faktor-faktor yang mempengaruhi kenyamanannya. Penelitian ini bertujuan untuk mengembangkan instrumen pengkajian kenyamanan dan mengidentifikasi faktor-faktor yang mempengaruhi kenyamanan melalui suatu pemodelan teoritis kenyamanan dalam pendekatan Kolcaba. Penelitian ini diawali dengan studi literatur, wawancara mendalam dengan 10 pasien, dan konsultasikan dengan 10 orang pakar dari berbagai keilmuan terkait, dilanjutkan dengan menggunakan metode cross sectional untuk uji construct validity dan uji model teoritis dengan menggunakan Structural Equation Modelling pada 308 pasien kanker payudara. Hasil penelitian ini adalah instrumen pengkajian kenyamanan kanker payudara yang diberi nama ldquo;PKKP rdquo; dan pemodelan teoritis kenyamanan pada pasien kanker payudara di Indonesia dengan pendekatan Kolcaba. Hasil penelitian menjelaskan bahwa dukungan emosi, perawatan paliatif, spiritual, dan usia pasien mempengaruhi kenyamanan pasien melalui mediator kondisi fisik dan emosi. Pengembangan perawatan paliatif yang memperhatikan aspek psikologis, spiritual, dan karakteristik usia pasien, diperlukan di Indonesia untuk meningkatkan kenyamanan pada pasien kanker, khususnya pada pasien kanker payudara.

ABSTRACT
Breast cancer rsquo patients in Indonesia frequently experience physical and psychologist discomforts. Nevertheless, it is difficult for nurses, to precisely measure comforts and identify factors affecting comforts among cancer patients. This study aimed to develop a comfort assessment tool and generate a theoretical comfort model for breast cancer patients in Kolcaba approach. The first stage of this study used literature reviews, in depth interviews with 10 cancer patients, and consulted with 10 experts, followed by cross sectional method for construct validity test and theoretical model tests using Structural Equation Modelling to 308 breast cancer patients. Results of our study were the comfort assessment breast cancer instrument and a theoretical comfort model for breast cancer patients in Indonesia. The results of this research concluded emotional support, palliative care, spiritual, and patients rsquo age affects patients 39 comfort through the mediator of physical and emotional conditions. Our study suggested the development of palliative care that takes into account psychologist, spiritual and patient rsquo s characteristic aspect to promote comforts among breast cancer patients."
[, ]: 2017
D2403
UI - Disertasi Membership  Universitas Indonesia Library
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Ida Ayu Putri Astiti
"Tujuan : Mengetahui pengaruh penerapan protokol buli di RSCM terhadap dosimetri dan toksisitas radiasi usus pada pasien kanker serviks saat menjalani radiasi eksterna. Metode : Penelitian adalah penelitian kohort retrospektif pada 236 subjek penelitian yang menjalankan radioterapi eksterna di IPTOR RSCM pada tahun 2019 – 2021. Subjek terbagi menjadi tiga kategori menurut perlakuan yaitu pasien tanpa protokol buli sebanyak 84 pasien, dengan protokol buli 300 - <500 mL sebanyak 35 pasien dan protokol buli 500 mL sebanyak 67 pasien. Uji normalitas menggunakan Kolmogorov-Smirnov, perbandingan rerata menggunakan Kruskal Wallis dan Mann Whittney. Perbandingan nominal kategorik menggunakan chi square. Analisis multivariat menggunakan regresi linier dan regresi logistik Hasil : Pasien tanpa diberikan instruksi protokol buli volume buli yang cenderung lebih kecil yaitu median 83,5 mL (min-maks) (29,2 – 570) dibandingkan dengan yang diberikan instruksi protokol buli 300 - <500 mL yaitu median (min-maks) 91,5 mL (25,6 – 409,4) dan yang diberikan instruksi protokol buli 500 mL yaitu 125 mL (15-462) (P=0,014). Protokol buli juga berpengaruh terhadap proporsi pasien dengan V45 bowel bag <195 mL, dimana pasien dengan protokol buli 11,12% mencapai V45 bowel bag <195mL, sedangkan pasien tanpa protokol buli hanya 3,2% yang mencapai V45 bowel bag <195 mL (P=0,04. CI 95%). Kesimpulan : Protokol buli yang telah diterapkan di IPTOR RSCM terlihat mempunyai pengaruh terhadap volume buli dan volume bowel bag namun tidak menunjukkan pengaruh terhadap toksisitas akut gastrointestinal bawah.

Objective: To determine the effect of bladder protocol at RSCM to the irradiated bowel volume and acute bowel toxicity in cervical cancer patients underwent external beam radiotherapy. Methods: This was a retrospective cohort study on 236 cervical cancer patients who underwent external radiotherapy at IPTOR RSCM in 2019-2021. Subjects were divided into three bladder protocol categories. Patients without bladder protocol (n=84), with 300 - <500 mL bladder protocol (n=85) and with 500 mL bladder protocol (n=67). Normality test using Kolmogorov-Smirnov, mean comparison using Kruskal Wallis and Mann Whittney. Comparison of categorical nominal using chi square. Multivariate analysis using linear regression and logistic regression. Results: Patients without bladder protocol had a smaller bladder volume, which median (min-max) was 83.5 mL (29.2 – 570) compared to those who were given a bladder protocol instruction of 300 - <500 mL which was 91, 5 mL (25.6 – 409.4) and those given 500 mL bladder protocol which median value was 125 mL (15-462) (P=0.014. 95% CI). Bladder protocol also caused more patients to achieve V45 bowel bag <195 mL which was 11.12% compared to those without bladder protocol which was 3,2% (P=0.04). Conclusion: The bladder protocol that has been applied at IPTOR RSCM seems to influence the bladder volume and bowel bag volume but did not show an effect on acute lower gastrointestinal toxicity.
"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2022
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UI - Tesis Membership  Universitas Indonesia Library
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Fahira Yusriya
"Latar belakang: Gangguan psikiatri depresi memiliki prevalensi yang tinggi pada pasien kanker leher rahim, yaitu 33 - 71,3% di dunia. Depresi yang dialami oleh pasien disebabkan oleh beberapa faktor, diantaranya adalah usia, kondisi sosial ekonomi, pendidikan, dan stadium kanker. Pasien dengan gangguan depresi memiliki kemungkinan perburukan prognosis yang lebih tinggi terkait kondisi kanker. Oleh sebab itu, penting dilakukan skrining depresi sehingga intervensi dini dapat dilakukan. Tujuan: Menghitung prevalensi dan faktor yang mempengaruhi gejala gangguan psikiatri depresi pada pasien kanker leher rahim Metode: Desain studi yang digunakan adalah studi potong lintang (cross-sectional). Pengambilan sampel dilakukan secara consecutive sampling dan gangguan depresi didiagnosis dengan kuesioner MINI ICD-10. Pengolahan data dilakukan menggunakan SPSS versi 20. Uji bivariat menggunakan uji Chi Square dan Fisher’s exact test yang selanjutnya dilakukan uji multivariat regresi logistik. Hasil: Dari 44 subjek penelitian, 28 subjek menderita depresi. Faktor yang memengaruhi, yaitu usia, pendidikan, pendapatan, dan stadium tidak memiliki hubungan yang signifikan secara statistik (p>0,05). Stadium lanjut memiliki risiko depresi 1,642 lebih tinggi dibandingkan dengan stadium awal (OR=1,642; CI95%: 0,463 – 5,828). Usia > 50 tahun, tamat SMA, dan pendapatan ≥ Rp2.500.000 merupakan faktor protektif terhadap kejadian depresi. Simpulan: Prevalensi depresi pada pasien kanker leher rahim adalah 63,6%. Faktor usia, pendidikan, pendapatan, dan stadium tidak memiliki hubungan yang signifikan dengan kejadian depresi
Background: Depressive psychiatric disorders have a high prevalence in cervical cancer patients, about 33 – 71,3% globally. Depression experienced by patients is caused by several factors, including age, sosioeconomic conditions, educational level, and cancer stage itself. Patients with depressive disorder have a higher probability of worsening cancer prognosis. Therefore, it is essential to make an early diagnosis so that intervention can be done. Objectives: To investigate the prevalence of depression symptoms in cervical cancer patients and analyze its risk factors. Methods: This study uses a cross-sectional study design. The sample is obtained by consecutive sampling, and depressive disorders were diagnosed using the MINI ICD-10 questionnaire. Data will be processed using SPSS version 20. Statistical analysis test used in this study are bivariate test using the Chi-Square test and Fisher's exact test, which was then carried out by the multivariate logistic regression test. Results: Of 44 research subjects, 28 patients suffered from depressive disorders. Factors affecting depression, namely age, education, income, and stage, are statistically insignificant (p>0,05). The OR result in the stage cancer variable implies that the advanced stage has a 1,642-fold risk to increase the incidence of depression in cervical cancer patients (OR = 1.642; 95% CI: 0.463 - 5.828). Age above 50 years old, graduated from high school, and monthly income ≥ IDR 2,500,000 are the protective factors against depression. Conclusion: The prevalence of depression in cervical cancer patients is 63,6%. Associated factors such as age, education, monthly income, and cancer stage are statistically insignificant with the incidence of depression in cervical cancer patients"
Depok: Fakultas Kedokteran Universitas Indonesia, 2021
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UI - Skripsi Membership  Universitas Indonesia Library
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Lisani Syukriani
"Cancer patients are at risk for having drug-related problems (DRPs) as they received concentrated electrolyte. This research aims to acquire characteristic descriptions also identify DRPs and their causes among hospitalized cancer patients receiving concentrated electrolyte in Dharmais Cancer Hospital. This is a descriptive research with cross-sectional design study. Data was collected retrospectively based on patients' prescriptions and laboratory results from January to March 2020 obtained from SIMRS. The DRPs were identified via Pharmaceutical Care Network Europe (PCNE) V6.2 and Lexicomp® was used to assess the drug-drug interactions. The data obtained were 159 study samples. The results illustrate that the sample characteristic consisted of 52.83% women and 47.17% men. The age of the patients consisted of 6.29% 19-29 years old, 10.69% 30-39 years old, 18.87% 40-49 years old, 33.96% 50-59 years old and 30.19 % 60 years old and above. The diagnosis of cancer was 98.74% classified as malignant cancer and 1.26% benign cancer. The condition of electrolyte disorder in hospitalized cancer patients consisted of 47.17% hyponatremia, 28.3% hypokalemia, and 24.53% metabolic acidosis. The results of DRPs identification showed that 75 patients (47.17%) had DRPs and 84 patients (52.83%) did not have DRPs. Types of DRPs that occurred was the Adverse Drug Reaction (64.97%) and the Drug Effectiveness (35.03%). Causes of DRPs was consisted of Drug Selection (84.08%) and Dose Selection (15.92%). Therefore, hospitalized cancer patients receiving concentrated electrolyte are susceptible to DRPs, so the review of prescription and therapy drug monitoring needs to be done carefully to reach the target therapy and improve patient safety.
Pasien kanker berisiko mengalami masalah terkait obat (MTO) saat menggunakan elektrolit konsentrat. Penelitian ini bertujuan untuk memperoleh gambaran karakteristik dan mengidentifikasi jenis dan penyebab MTO pada pasien kanker rawat inap yang mendapat elektrolit pekat di Rumah Sakit Kanker Dharmais. Penelitian ini merupakan penelitian deskriptif dengan desain penelitian cross sectional. Pengumpulan data dilakukan secara retrospektif berdasarkan resep pasien dan hasil laboratorium periode Januari-Maret 2020 yang diperoleh dari SIMRS. Identifikasi MTO menggunakan klasifikasi Pharmaceutical Care Network Europe (PCNE) versi 6.2 dan Lexicomp® untuk menganalisis potensi interaksi obat-obat. Data yang diperoleh sebanyak 159 sampel penelitian. Hasil penelitian menunjukkan bahwa karakteristik sampel terdiri dari 54,09% perempuan dan 45,91% laki-laki. Rentang usia pasien terdiri dari 6,29% berusia 19-29 tahun, 10,69% berusia 30-39 tahun, 18,87% berusia 40-49 tahun, 33,96% berusia 50-59 tahun, dan 30,82%. berusia 60 tahun ke atas. 98,74% dari diagnosis kanker diklasifikasikan sebagai kanker ganas dan 1,26% adalah kanker jinak. Kondisi gangguan keseimbangan elektrolit pada pasien kanker rawat inap adalah hiponatremia 47,17%, hipokalemia 28,3%, dan asidosis metabolik 24,53%. Hasil identifikasi MTO menunjukkan sebanyak 75 pasien (47,17%) mengalami MTO dan 84 pasien (52,83%) tidak mengalami MTO. Jenis MTO yang terjadi adalah Reaksi Obat Tidak Diinginkan (ROTD) (64,97%) dan Masalah Efektivitas Terapi (35,03%). Penyebab MTO terdiri dari pemilihan obat (84.08%) dan pemilihan dosis (15.92%). Oleh karena itu, pasien kanker rawat inap yang mendapat elektrolit pekat cenderung mengalami MTO, sehingga penilaian resep dan pemantauan terapi obat perlu dilakukan secara cermat untuk mencapai target terapeutik dan meningkatkan keselamatan pasien."
Depok: Fakultas Farmasi Universitas Indonesia, 2020
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UI - Skripsi Membership  Universitas Indonesia Library
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Sindi Fantika
"ABSTRAK
Kapesitabin adalah salah satu obat kemoterapi oral yang banyak digunakan dan dilaporkan memiliki efektivitas yang sama dengan kemoterapi intravena 5 fluorourasil. Akan tetapi, kapesitabin yang berkaitan dengan banyak efek samping dan memiliki jadwal siklus penggunaan yang kompleks berpotensi meningkatkan ketidakpatuhan terhadap minum obat. Tujuan article review ini adalah menelusuri faktor-faktor yang memengaruhi tingkat kepatuhan pasien kanker terhadap terapi kapesitabin. Pencarian literatur dilakukan pada pangkalan data seperti PubMed, Sage, Sciencedirect, dan Springer dengan berpedoman pada Preferred Reporting Items for Systematic reviews and Meta Analysis. Berdasarkan hasil penelusuran literatur didapatkan tujuh artikel yang sesuai dengan kriteria inklusi. Hasil review menunjukkan bahwa tingkat kepatuhan pasien kanker yang mendapat kapesitabin bervariasi antara 76,7% sampai ≤105%. Sedangkan faktor faktor yang memengaruhi tingkat kepatuhan berhubungan dengan efek samping, lupa minum obat, perkembangan toksisitas, penurunan kualitas hidup, hambatan bahasa dalam berkomunikasi, situasi sosial, keyakinan pasien pada terapi kapesitabin, dan kepuasan terhadap petugas medis.

ABSTRACT
Capecitabine is one of the most widely used oral chemotherapy drugs and is reported have the same effectiveness as 5 fluorouracil intravenous chemotherapy. However, capecitabine, which is associated with many side effects, and has complicated dosage regiment cycle, have the potential to increase non-adherence medication. This review article aimed to explore the factors that influence the level of adherence among cancer patients using capecitabine as chemotherapy. Electronic searches were performed on databases including PubMed, Sage, Sciencedirect, and Springer based on Preferred Reporting Items for Systematic reviews and Meta Analysis. Seven articles that fit the inclusion criteria were obtained. The results of the review showed that the level of adherence of cancer patients who received capecitabine varied between 76.7% to ≤105%. While the factors that influence the level of adherence were related to side effects, forgetting to take medication, the development of toxicity, decreased quality of life, language barrier, social situations, medication belief, and satisfaction with healthcare providers."
Depok: Fakultas Farmasi Universitas Indonesia, 2020
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UI - Skripsi Membership  Universitas Indonesia Library
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Yati Afiyanti
"Objective: The number of gynecological cancer survivors is
increasing in Indonesia, and these women often require physical
and emotional support from their male partners as primary
caregivers. However, the male caregiver`s need for biological,
psychological, and social support is often neglected. This study
aims to assess the demographic and clinical determinants
affecting the unmet supportive care needs of the gynecological
cancer survivors` husbands in Indonesia. Methods: This
cross‑sectional survey involved 152 husbands of survivors who
were recruited by a consecutive sampling method in two national
referral hospitals. A self‑administered Cancer Survivors` Partners
Unmet Needs Questionnaire was used for data collection.
Multiple linear regression was performed to analyze the data.
Results: The majority of participants (97.4%) reported at least one
unmet need. The primary unmet needs were legal services (71.1%),
financial support (70.4%), cancer recurrence concerns (69.7%), and
ongoing health support (66.4%). These needs were significantly
associated with the wife`s radio‑chemotherapy and lower
household income (P < 0.01) and also related to the husband`s
education level, duration of caregiving, and wife`s cancer stage.
Conclusions: Husbands of gynecological cancer survivors in
Indonesia reported a need for legal, financial, and health‑care
information and assistance. Multidisciplinary professionals
should be involved in developing policy and interventions which
facilitate the social‑economic protection of survivors and their
husbands, as well as comprehensive care needs to enhance the
women`s survival rate.
"
Wolter Kluwer, 2021
MK-Pdf
Artikel Jurnal  Universitas Indonesia Library
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