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Sukara Safril Kusuma Jaya
"Latar belakang: Hubungan antara TB dan DM sudah lama diketahui. Sistem imun rendah pada DM sehingga risiko berkembangnya TB laten menjadi TB aktif lebih tinggi. Penderita DM memiliki 2-3 kali risiko untuk menderita TB dibanding tanpa DM. Sekitar 10% kasus TB secara global berhubungan dengan DM. Prevalensi TB DM berdasarkan penelitian potong lintang oleh Wijayanto di Poli Endokrin RSUP Persahabatan pada pasien DM tipe 2 dari Oktober sampai Nopember 2013 adalah 28,2%. Pablos-Mendez dkk. menemukan bahwa hanya DM yang kurang terkontrol atau tidak terkontrol dikaitkan dengan peningkatan risiko TB.
Tujuan: Tujuan utama dari penelitian ini adalah untuk menentukan sensitivitas dan spesifisitas mikroskop sputum BTA dan Xpert MTB / RIF untuk diagnosis TB pada pasien dengan DM.
Metode: Penelitian ini adalah studi analitik deskriptif potong lintang pada pasien kelompok DM yang masih menjalani pengobatan di RS Persahabatan dari bulan Mei 2014 sampai jumlah sampel tercapai. Penelitian akan dilakukan di poli Paru dan Penyakit Dalam divisi Endokrin dan Metabolik RS Persahabatan. Pasien dengan keluhan tuberklosis baik yang belum pernah minum OAT atau dengan riwayat pengobatan sbelumnya dan didukung dari foto toraks yang menunjukan gambaran kecurigaan TB akan dilakukan pemeriksaan diagnostik mikrobiologis sputum BTA dan Xpert MTB/RIF.
Hasil: Tujuh puluh subjek diskrining dan hanya 55 subjek memenuhi kriteria inklusi. Terdapat 32 laki-laki (58,2%) dan 23 perempuan (41,8%). Umur antara 25-72 tahun. Indeks massa tubuh kurang 11 (20%), normal 31(56,4%) dan lebih 13(23,6%). Gula darah antara 110-481 mg/dl. Lama menderita DM <5 tahun adalah 40 (72,7%), 5-10 tahun adalah 7(12,7 %), 10-15 tahun adalah 6(10,9%) dan >15 tahun adalah 2(3,6%). HbA1c terkontrol 11(20%) dan tidak terkontrol 44(80 %). Riwayat tidak pernah TB 41 (74,5%), TB sembuh 9(16,4%) dan gagal atau putus obat 5 (9,1%). Sputum BTA(+) 29 (52,7%) dan Xpert MTB/RIF(+) 36(65,5%). Tingkat HbA1c tidak terkontrol BTA(+)/Xpert MTB/RIF(+) 30 (54,5%). Uji diagnostik kedua alat memiliki sensitivitas 77,8 % dan spesifisitas 94,7%.
Kesimpulan: Xpert MTB/RIF memiliki nilai kepositifan yang lebih tinggi daripada sputum BTA dalam mendeteksi M.Tb. Tidak ada perbedaan sensitivitas dan spesifisitas pemeriksaan mikroskopik sputum BTA dan Xpert MTB/RIF dalam upaya penegakan diagnosis TB pada pasien DM.

Background: The relationship between Tuberculosis (TB) and Diabetes Mellitus (DM) has long been known. People with DM have 2-3 times the risk of developing TB. The prevalence of TB-DM based on cross sectional study by Wijayanto in Endocrine clinic at Persahabatan Hospital in DM type 2 patients in 2013 was 28.2%. Pablos-Mendez et al. found that only DM poorly controlled or uncontrolled associated with the increased risk of TB.
Purpose: The main purpose of this study is to determine the sensitivity and specificity of Acid Fast Bacilli (AFB) smear and Xpert MTB/RIF for diagnosis of TB in DM.
Methods: This study is a cross-sectional descriptive analytic study in patients with DM group who are still undergoing treatment at Persahabatan Hospital from May 2014. The study is conducted in Pulmonary clinic and Internal Medicine clinic. Patients with DM who have TB complaints that have not been taken either TB drug or with a history of treatment and supported from chest X-ray shows the suspicion of TB will require the microbiological diagnosis of AFB smear and Xpert MTB/RIF.
Result: Seventy subjects are screening and only 55 subjects meet the inclusion criteria. There are 32 males (58.2%) and 23 females (41.8%). There are ages between 25-72 years old. Their body mass index are less than 11(20%), normal 31(56.4%) and over 13(23.6%). The blood sugar is between 110-481 g/dl. The length of suffer DM <5 years are 40(72.7%), 5-10 years were 7(12.7%), 10-15 years were 6(10.9%) and >15 years are 2(3.6%). The controlled HbA1c is 11(20%) and uncontrolled is 44(80%). By history of TB which has never been suffered are 41(74.5%), treatment cured are 9(16.4%) and failure or withdrawal are 5(9.1%). Smear of AFB(+)ve are 29(52,7%) and Xpert MTB/RIF(+) are 36(65,5%). Uncontrolled HbA1c levels pulmonary TB with AFB smear/Xpert (+)ve are 30(54.5%). Sensitivity and specificity by using both are 77.8% and 94.7%.
Conclusion: The Xpert MTB/RIF has a higher value of positivity that detect M.Tb than AFB smear.There is no difference in the sensitivity and specificity of AFB smear and Xpert MTB/RIF for TB diagnosis in patients with DM.
"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2014
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UI - Tugas Akhir  Universitas Indonesia Library
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Wiendo Syah Putra Yahya
"Latar belakang : Terapi target baru golongan EGFR-TKi telah direkomendasikan sebagai terapi lini pertama untuk pasien KPKBSK non skuamosa dengan mutasi EGFR positif. Belum tersedia data di Indonesia tentang efikasi dan toksisitas terapi target baru EGFR-TKi pada pasien KPKBSK dengan mutasi EGFR positif dibandingkan dengan kemoradioterapi pada EGFR wild type di RSUP Persahabatan Jakarta.
Metode : Disain penelitian ini kohort retrospektif melalui resume medis pasien KPKBSK non skuamosa di RSUP Persahabatan periode Januari 2010 sampai Juli 2014. Teknik pengambilan sampel adalah consequtive sampling. Jumlah sampel 61 pasien yang terdiri dari 31 pasien KPKBSK non skuamosa dengan mutasi EGFR positif yang diberikan terapi target baru EGFR-TKi dan 30 pasien dengan EGFR wild type yang diberikan kemoradioterapi.
Hasil : Karakteristik pasien KPKBSK non skuamosa dengan mutasi EGFR yang positif adalah laki-laki sebanding dengan perempuan, bukan perokok, mutasi delesi di ekson 19 sebanding dengan mutasi L858R di ekson 21, angka tahan hidup 1 tahun 48,37%, rata-rata time to progression 284 hari sedangkan pasien EGFR wild type adalah laki-laki lebih dominan, perokok, angka tahan hidup 1 tahun 33,3% dan rata-rata time to progression 210 hari dan overall survival 293 hari. Uji T independen menunjukan terdapat hubungan yang bermakna antara terapi target baru EGFR-TKi dengan lama time to progression (p=0,028). Toksisitas yang sering ditemukan pada terapi target baru EGFR-TKi adalah mual- muntah (6,8%) diare (16,2%), alopesia (3,2%) dan kelainan kulit kemerahan (12,9%) sedangkan pada kelompok kemoradioterapi toksisitas yang ditemukan adalah anemia (13,3%), leukopenia (6,7%) dan trombositopenia (3,3%).
Kesimpulan : Pasien KPKBSK non skuamosa dengan mutasi EGFR yang positif dan diberikan terapi target baru EGFR-TKi memiliki time to progression yang lebih lama dan toksisitas yang dapat ditoleransi.

Background: The new targeted therapy of EGFR-TKi has been recommended as first-line therapy for patients with NSCLCC non-squamous with mutated EGFR. There are no data about the efficacy and toxicity of the new targeted therapy of EGFR-TKi in NSCLC non-squamous with mutated EGFR compared with chemotradiotherapy in wild type at Persahabatan Hospital, Jakarta.
Methods: The design of study are retrospective cohort through medical records of NSCLC non-squamous patients in the Department of Pulmonology and Respiratory Persahabatan Hospital in January 2010 to July 2014. The sampling technique is consequtive sampling. The number of samples are 61 patients consisted of 31 patients with NSCLC non-squamous with mutated EGFR treated the new targeted therapy of EGFR-TKi and 30 patients with EGFR wild type treated chemoradiotherapy.
Results: The characteristics of NSCLC non-squamous patients with positive mutated EGFR are male compared to women, non-smokers, a deletion mutation in exon 19 L858R mutation comparable with in exon 21, 1-year survival 41,9%, mean time to progression is 284 days and patients of wild-type mutation are more dominant in males, smokers, 1-year survival 33,3% and mean time to progression is 210 days and overall survival is 293 days . The independent t test showed a significant relationship between the new targeted therapy with EGFR-TKi and TTP (p = 0.028). The most common adverse events in the EGFR-TKi group are nausea and vomitus 96,8%), diarrhea (16,2%), alopecia (3,2%) and rash (12,9%) and in the chemotherapy group, anemia (13,3%), leucopenia (6,7%) and thrombocytopenia (3,3%).
Conclusions: The EFGR-TKi for patients with advanced non small cell lung cancer who are selected on the basis of EGFR mutations improve time to progression with acceptable toxicity.
"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2014
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UI - Tugas Akhir  Universitas Indonesia Library
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Jerry Nasarudin
"ABSTRAK
Latar belakang : Pasien HIV berisiko 20-37 kali lipat terinfeksi TB, dan TB
merupakan penyebab kematian tertinggi pada HIV. Resistensi OAT menjadi
masalah utama dalam pengobatan TB terutama pada pasien HIV, hal ini berujung
pada peningkatan mortalitas dan biaya. Rifampisin merupakan OAT utama,
dibuktikan dengan kesembuhan yang rendah pada regimen tanpa rifampisin,
sehingga perlu diketahui prevalensi resistensi rifampisin dan faktor-faktor yang
mempengaruhi pada pasien TB-HIV.
Tujuan : Mengetahui prevalensi resistensi rifampisin pada pasien TB-HIV dan
faktor-faktor yang mempengaruhi.
Metode : Studi potong lintang terhadap 196 pasien TB-HIV yang menjalani
pemeriksaan Xpert MTB-RIF di poli pelayanan terpadu HIV RSUPN Cipto
Mangunkusumo selama tahun 2012-2015. Analisa bivariat untuk mengetahui
hubungan faktor-faktor dengan kejadian resistensi rifampisin. Analisa multivariat
menggunakan uji regresi logistik.
Hasil dan Pembahasan : Pada 196 pasien yang menjadi subjek penelitian,
didapatkan prevalensi resistensi rifampisin sebesar 13,8%. Usia, jenis kelamin,
riwayat penggunaan ARV, dan TB ekstra paru tidak berhubungan dengan
kejadian resistensi rifampisin pada TB-HIV. CD4 < 100 mempengaruhi kejadian
resistensi rifampisin (OR 2,57; 95% IK 0,99-6,69), Riwayat pengobatan TB
mempengaruhi kejadian resistensi rifampisn (OR 3,98; 95% IK 1,68-9,44).
Kesimpulan : Prevalensi resistensi rifampisin TB-HIV di RSUPN Cipto
Mangunkusumo sebesar 13,8%. Riwayat TB mempengaruhi kejadian resistensi rifampisin pada pasien TB-HIV. ABSTRACT
Background: HIV patients have 20-37 fold risk of getting TB infection and TB is
the leading cause of death among them. Anti tuberculosis drug resistance is a
major problem in the treatment of tuberculosis with rifampicin as one of the main
drug. We need more information about prevalence of rifampicin resistance and its
contributing factors in TB-HIV patients.
Aim: To determine the prevalence of rifampicin resistance in TB-HIV patients
and its contributing factors.
Method : A cross sectional study of 196 TB-HIV patients who underwent Xpert
MTB/RIF examination at Cipto Mangunkusumo Hospital during the year 20122105.
Correlation
between
prevalence
of
rifampicin
resistance
and
its
contributing
factors
was done using bivariate analysis. Multivariate analysis was done using
logistic regression test.
Result and Discussion : From 196 patients, we found prevalence of 13,8%
rifampicin resistance. CD4 < 100 affects the incidence of rifampicin resistance
(OR2.5;95% CI 0.99-6.69). Hiistory of TB treatment affects the incidence of
rifampicin resistance (OR3.98;95%CI 1.68-9.44).
Conclusion : Prevalence of rifampicin resistance in TB-HIV patients in Cipto
Mangunkusumo Hospital is 13.8%. History of TB treatment affects the incidence
of rifampicin resistance in TB-HIV patients. ;Background: HIV patients have 20-37 fold risk of getting TB infection and TB is
the leading cause of death among them. Anti tuberculosis drug resistance is a
major problem in the treatment of tuberculosis with rifampicin as one of the main
drug. We need more information about prevalence of rifampicin resistance and its
contributing factors in TB-HIV patients.
Aim: To determine the prevalence of rifampicin resistance in TB-HIV patients
and its contributing factors.
Method : A cross sectional study of 196 TB-HIV patients who underwent Xpert
MTB/RIF examination at Cipto Mangunkusumo Hospital during the year 20122105.
Correlation
between
prevalence
of
rifampicin
resistance
and
its
contributing
factors
was done using bivariate analysis. Multivariate analysis was done using
logistic regression test.
Result and Discussion : From 196 patients, we found prevalence of 13,8%
rifampicin resistance. CD4 < 100 affects the incidence of rifampicin resistance
(OR2.5;95% CI 0.99-6.69). Hiistory of TB treatment affects the incidence of
rifampicin resistance (OR3.98;95%CI 1.68-9.44).
Conclusion : Prevalence of rifampicin resistance in TB-HIV patients in Cipto
Mangunkusumo Hospital is 13.8%. History of TB treatment affects the incidence
of rifampicin resistance in TB-HIV patients. ;Background: HIV patients have 20-37 fold risk of getting TB infection and TB is
the leading cause of death among them. Anti tuberculosis drug resistance is a
major problem in the treatment of tuberculosis with rifampicin as one of the main
drug. We need more information about prevalence of rifampicin resistance and its
contributing factors in TB-HIV patients.
Aim: To determine the prevalence of rifampicin resistance in TB-HIV patients
and its contributing factors.
Method : A cross sectional study of 196 TB-HIV patients who underwent Xpert
MTB/RIF examination at Cipto Mangunkusumo Hospital during the year 20122105.
Correlation
between
prevalence
of
rifampicin
resistance
and
its
contributing
factors
was done using bivariate analysis. Multivariate analysis was done using
logistic regression test.
Result and Discussion : From 196 patients, we found prevalence of 13,8%
rifampicin resistance. CD4 < 100 affects the incidence of rifampicin resistance
(OR2.5;95% CI 0.99-6.69). Hiistory of TB treatment affects the incidence of
rifampicin resistance (OR3.98;95%CI 1.68-9.44).
Conclusion : Prevalence of rifampicin resistance in TB-HIV patients in Cipto
Mangunkusumo Hospital is 13.8%. History of TB treatment affects the incidence
of rifampicin resistance in TB-HIV patients. "
Fakultas Kedokteran Universitas Indonesia, 2016
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UI - Tugas Akhir  Universitas Indonesia Library
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Siregar, Yenni Sari
"ABSTRAK
Latar belakang : Prevalens malnutrisi pada kanker paru di rumahsakit cukup tinggi namun masalah tersebut sering tidak terdeteksi sejak awal. Pemeriksaan nutrisi secara rutin juga masih jarang dilakukan karena keterbatasan waktu, kondisi pasien juga hal-hal lain.
Penyebab malnutrisi pada pasien kanker bersifat multifaktorial dapat merupakan proses dari penyakit kanker itu sendiri, sebagai efek dari terapi kanker atau bahkan keduanya. Pada penelitian ini akan diteliti perubahan yang terjadi pada subjek setelah pemberian 3 siklus kemoterapi berdasarkan parameter indeks massa tubuh (IMT), persentase berat otot rangka dengan mengunakan alat bioelectrical impendance analysis (BIA) dan penilaian kadar albumin.
Tujuan :Mengetahui perubahan status gizi pada pasien KPKBSK berdasarkan arameter IMT, persentase otot rangka dan kadar albumin sebelum dan setelah 3 siklus kemoterapi.
Metode : Penelitian pre-post experimental pada pasien KPKBSK tahun 20132014 sebanyak 33 subjek yang mendapatkan kemoterapi dengan menilai perubahan IMT, persentase berat otot rangka dengan menggunakan alat BIA dan kadar albumin.
Hasil : Dari 33 subjek penelitian, status gizi kurang berdasarkan IMT sebanyak 17 subjek (56,6%), berdasarkan persentase otot rangka tidak normal 30 subjek (90,9%) dan hipoalbuminemia 27 subjek (81,8 %). Perubahan status gizi dengan penilaian parameter IMT, persentase otot rangka dan albumin sebelum kemoterapi I dan setelah kemoterapi 3 siklus dalam penilaian skala kategorik tidak didapatkan perubahan bermakna dengan nilai IMT (p=1,000), persentase otot rangka (p=1,0000) dan kadar albumin (p=1,000).
Kesimpulan : Terdapat perubahan bermakna dalam penilaian skala numerik dengan nilai median IMT sebelum kemoterapi I adalah 18,4 (16,90-25,00), median IMT setelah kemoterapi III adalah 18 (16,60-24) p=0,000. Nilai median albumin sebelum kemoterapi I adalah 3(2,80-4,0), median albumin setelah kemoterapi III adalah 2,90 (2,60-3,90) p=0,000. Nilai range persentase otot rangka sebelum kemoterapi I (26,7-32,2) menjadi (26,7-32,1) dan nilai mean setelah kemoterapi 29,58 ±1,69 dengan nilai p= 0,001.

ABSTRACT
Introduction : The prevalence of malnutrition in lung cancer at hospital is quite high but the problem is often not detected early. Nutrition routine examination is still rarely done due to time constraints, the condition of the patient are also other things. The cause of malnutrition in cancer patients is multifactorial that can be a process of cancer itself, as the effects of cancer therapy or both. This research investigates the changes that occur in the subject after administrating of 3 cycles of chemotherapy based on the parameters body mass index (BMI), percentage of skeletal muscle weight by using the tool bioelectrical impendance analysis (BIA) and the assessment of albumin.
Purpose: Knowing the changes in nutritional status in patients with KPKBSK based on parameters of BMI, the weight percentage of skeletal muscle and the albumin levels before and after 3 cycles chemotherapy.
Methods: Pre-post experimental study in patients with KPKBSK in the year of 2013-2014, a total of 33 subjects who received chemotherapy by assessing changes in BMI, weight percentage of skeletal muscle by using BIA and albumin.
Result: There are 33 subjects, less nutritional status based on BMI 17 subjects (56.6%), based on the percentage of abnormal skeletal muscle of 30 subjects (90.9%) and hypoalbuminemia 27 (81.8%). Parameter assessment of nutritional status with BMI, skeletal muscle percentage and albumin before chemotherapy I and after 3 cycles of chemotherapy in a categorical scale not found significant changes in the value of BMI (p=1.000), the percentage of skeletal muscle (p = 1.0000) and albumin levels (p = 1.000).
Conclusion:
There are significant changes in the assessment of a numerical scale with the median value of BMI before chemotherapy I are 18.4 (16.90 - 25.00), the median BMI after chemotherapy III is 18 (16.60 - 24) p = 0.000. The median value of albumin before chemotherapy I is 3 (2.80 - 4.0), the median albumin after chemotherapy III is (2.60 - 3.90) p = 0.000. Value of range skeletal muscle percentage before chemotherapy I becomes 26.7-32.2 26.7 - 32.1 and the mean value of 29.58 ± 1.69 after chemotherapy with p = 0.001.
"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2014
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UI - Tugas Akhir  Universitas Indonesia Library
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Ery Irawan
"ABSTRAK
Latar Belakang: dahak BTA mikroskopik adalah teknik diagnostik cepat yang paling
banyak digunakan untuk mendiagnosis TB paru. Di RSUP Persahabatan, pemeriksaan
dahak BTA mikroskopik membutuhkan tiga pemeriksaan sampel dahak lebih dari dua
hari, (sewaktu pertama, pagi, sewaktu kedua). Pengambilan dua sampel dahak akan
mengurangi waktu, uang dan beban kerja laboratorium mikrobiologi
Tujuan: Penelitian ini bertujuan untuk mendapatkan sensitivitas dan spesifisitas
pemeriksaan dahak BTA mikroskopik dari tiga bahan pemeriksaan dahak dan dua
bahan pemeriksaan dahak.
Metode: Kami secara acak mengumpulkan data demografi dan hasil laboratorium (hasil
dahak BTA dan hasil biakan M.tuberculosis) dari pasien terduga TB kasus baru di RSUP
Persahabatan dari data bulan Januari 2012 hingga Desember 2013. Subjek harus berusia
minimal 15 tahun dan bukan pasien TB MDR dan bukan pasien HIV
Hasil: Dari 360 pasien terduga TB paru, sebanyak 210/360 (58,3%) memiliki hasil
biakan M. tuberculosis positif. Sensitivitas 100% dan spesifisitas 69.2% pada hasil
pemeriksaan BTA mikroskopik tiga kali (S1, P, S2) dan hasil pemeriksaan BTA
mikroskopik dua kali sensitivitasnya 89.8% dan spesifisitas 94.1%.
Kesimpulan: Hasil pemeriksaan dahak BTA mikroskopik 2 kali pemeriksaan
memberikan spesifisitas yang lebih tinggi bila dibandingkan dengan hasil pemeriksaan
3 kali dahak BTA mikroskopik dan memiliki sensitivitas yang masih cukup tinggi.
ABSTRACT
Background: Sputum smear microscopy is the rapid diagnostic technique that most
widely used for diagnosing pulmonary tuberculosis. In Persahabatan hospital, sputum
smear microscopy requires three sputum sample examinations over two days, (spot1,
morning, spot2). Collection of two sputum samples would reduce time, money and
work load of microbiology laboratory.
Objectives: This study aimed to get sensitivity and specificity of sputum smear
microscopy from three sputum samples collection and two sputum samples collection.
Methods: We randomly collected demography and laboratory data (sputum smear and
M.tuberculosis culture result) of presumptive TB new cases in Persahabatan hospital
from January 2012 to Desember 2013. Subjects must be 15 years old minimum, non
multidrug-resistant TB presumptive and have non reactive HIV status.
Results: Of 360 presumptive TB patients, 58.3% have M.tuberculosis positive culture
results. Senstivity and specificity of sputum smear microscopy from three sputum
samples collection (S1, M, S2) are 100% and 69.2%. Smear microscopy of two samples
collection Sensitivity and specificity sputum smear microscopy 89.8% and 94.1%.
Conclusion: Sputum smear microscopy test result from 2 sputum collections gives
increase specificity compared to smear microscopy of 3 samples and have highly sensitivity.
;Background: Sputum smear microscopy is the rapid diagnostic technique that most
widely used for diagnosing pulmonary tuberculosis. In Persahabatan hospital, sputum
smear microscopy requires three sputum sample examinations over two days, (spot1,
morning, spot2). Collection of two sputum samples would reduce time, money and
work load of microbiology laboratory.
Objectives: This study aimed to get sensitivity and specificity of sputum smear
microscopy from three sputum samples collection and two sputum samples collection.
Methods: We randomly collected demography and laboratory data (sputum smear and
M.tuberculosis culture result) of presumptive TB new cases in Persahabatan hospital
from January 2012 to Desember 2013. Subjects must be 15 years old minimum, non
multidrug-resistant TB presumptive and have non reactive HIV status.
Results: Of 360 presumptive TB patients, 58.3% have M.tuberculosis positive culture
results. Senstivity and specificity of sputum smear microscopy from three sputum
samples collection (S1, M, S2) are 100% and 69.2%. Smear microscopy of two samples
collection Sensitivity and specificity sputum smear microscopy 89.8% and 94.1%.
Conclusion: Sputum smear microscopy test result from 2 sputum collections gives
increase specificity compared to smear microscopy of 3 samples and have highly sensitivity.
;Background: Sputum smear microscopy is the rapid diagnostic technique that most
widely used for diagnosing pulmonary tuberculosis. In Persahabatan hospital, sputum
smear microscopy requires three sputum sample examinations over two days, (spot1,
morning, spot2). Collection of two sputum samples would reduce time, money and
work load of microbiology laboratory.
Objectives: This study aimed to get sensitivity and specificity of sputum smear
microscopy from three sputum samples collection and two sputum samples collection.
Methods: We randomly collected demography and laboratory data (sputum smear and
M.tuberculosis culture result) of presumptive TB new cases in Persahabatan hospital
from January 2012 to Desember 2013. Subjects must be 15 years old minimum, non
multidrug-resistant TB presumptive and have non reactive HIV status.
Results: Of 360 presumptive TB patients, 58.3% have M.tuberculosis positive culture
results. Senstivity and specificity of sputum smear microscopy from three sputum
samples collection (S1, M, S2) are 100% and 69.2%. Smear microscopy of two samples
collection Sensitivity and specificity sputum smear microscopy 89.8% and 94.1%.
Conclusion: Sputum smear microscopy test result from 2 sputum collections gives
increase specificity compared to smear microscopy of 3 samples and have highly sensitivity.
"
Fakultas Kedokteran Universitas Indonesia, 2015
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UI - Tugas Akhir  Universitas Indonesia Library