Ditemukan 143 dokumen yang sesuai dengan query
Anandhara Indriani Khumaedi
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ABSTRAK
Background: periodontitis is a major cause of chronic infection in diabetic patients. Diabetic patients have four-fold risk of having cardiovascular disease. Chronic inflammation caused by periodontitis, a non-traditional cardiovascular risk factor is widely known to play a major role in atherogenesis. Among non-diabetics, an association has been found between periodontitis and arterial stiffness, but in diabetic patients the result is inconsistent. No study has investigated either the proportion of periodontitis or its correlation with arterial ...
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Jakarta: University of Indonesia. Faculty of Medicine, 2018
610 UI-IJIM 50:4 (2018)
Artikel Jurnal Universitas Indonesia Library
Budi Y. Setianto
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Current guidelines for the management of patients with acute coronary syndromes (ACSs) focus on the electrocardiogram to divide patients into ST-elevation acute myocardial infarction (STEMI) or non-ST-elevation acute myocardial infarction (NSTEMI)/unstable angina (UA). Patients with STEMI in the earliest time will receive reperfusion therapy to destruct occlusive thrombus. An ST segment elevation is the sine qua non for diagnosing acute total coronary occlusion causing transmural myocardial infarction. Left circumflex coronary artery (LCx) occlusion is often ...
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Jakarta: University of Indonesia. Faculty of Medicine, 2017
610 UI-IJIM 49:1 (2017)
Artikel Jurnal Universitas Indonesia Library
Hilman Zulkifli Amin
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ABSTRACT
Atherosclerosis is a chronic inflammatory disorder involving innate and adaptive immunity process. Effector T cell (Teff) responses promote atherosclerotic disease, whereas regulatory T cells (Tregs) have been shown to play a protective role against atherosclerosis by down-regulating inflammatory responses which include multiple mechanisms. Compelling experimental data suggest that shifting the Treg/Teff balance toward Tregs may be a possible therapeutic approach for atherosclerotic disease, although the role of Tregs in human atherosclerotic disease has not been ...
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Jakarta: University of Indonesia. Faculty of Medicine, 2017
610 UI-IJIM 49: 1 (2017)
Artikel Jurnal Universitas Indonesia Library
Zulkifli Amin
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ABSTRACT
Lung cancer is a devastating disease with a high incidence, mortality and morbidity rate, especially in developing countries. Conventional treatment with cytotoxic chemotherapy has some limitations attributed to chemoresistance and toxicity. Recent advances have shown that first generation Tyrosine Kinase Inhibitor (TKI), Gefitinib and Erlotinib, and the newest available second generation Tyrosine Kinase Inhibitor (TKI), Afatinib, have the potential to be an option in the management of patients with epidermal growth factor receptor/ EGFR mutation ...
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Jakarta: University of Indonesia. Faculty of Medicine, 2017
610 UI-IJIM 49: 1 (2017)
Artikel Jurnal Universitas Indonesia Library
Robert Sinto
Jakarta: University of Indonesia. Faculty of Medicine, 2018
610 UI-IJIM 50:4 (2018)
Artikel Jurnal Universitas Indonesia Library
Partini P. Trihono
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Background: Each kidney injury may develop into chronic kidney disease (CKD) and end stage renal disease (ESRD) that associates with high mortality and socio-economic burden. There is limited data about clinical characteristics of children having CKD in developing countries, espesially in Indonesia.
Objective: To describe clinical profiles and characteristics of kidney diseases in adolescents aged 15-18 years.
Methods: This study was a cross-sectional study which used data from National Basic Health Survey (Riskesdas) 2013. There were 2 ...
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Jakarta: University of Indonesia. Faculty of Medicine, 2018
610 UI-IJIM 50:4 (2018)
Artikel Jurnal Universitas Indonesia Library
Noorwati Sutandyo
Jakarta: University of Indonesia. Faculty of Medicine, 2018
610 UI-IJIM 50:4 (2018)
Artikel Jurnal Universitas Indonesia Library
Tirza Z. Tamin
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ABSTRAK
Background: obesity and osteoarthritis have strong inter-relationship with multi-factorial mechanism that
caused pain and leads to decreased quality of life. Exercise has been identified as prevention and management
against obesity and joint pain. This systematic review aims to assess the effect between exercises compared to diet
group for chronic pain management, physical and mental function in obese patients with chronic musculoskeletal
problem. Methods: we performed a systematic search of Randomized Control Trial studies from Cochrane CentralRegister of Controlled Trials ...
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Jakarta: University of Indonesia. Faculty of Medicine, 2018
610 UI-IJIM 50:4 (2018)
Artikel Jurnal Universitas Indonesia Library
A. Makbul Aman
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ABSTRAK
Background: the familial nature of type 2 diabetes is manifested by the presence of insulin resistance in non-diabetic first degree relatives. Most of these studies have been performed in middle-aged and there is only few published studies in young age individuals and adolescents. This study aimed to determine the relationship between parents history of type-2 diabetes with metabolic syndrome component and insulin resistance in adolescent non-diabetic subjects. Methods: this was a cross sectional study comparing ...
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Jakarta: University of Indonesia. Faculty of Medicine, 2018
610 UI-IJIM 50:4 (2018)
Artikel Jurnal Universitas Indonesia Library
Andika Afriansyah
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ABSTRAK
In the past 10 years, recent development of targeted therapy in metastatic renal cell carcinoma (mRCC) has provided a new hope and significantly enhanced the prognosis of the disease. Three class of targeted therapy were developed, including multi-targeted tyrosine kinase inhibitors (TKI), the mammalian target of rapamycin (mTOR) complex-1 kinase inhibitors, and the humanized antivascular endothelial growth factor (VEGF) monoclonal antibody. Hence, the objective of this article was to critically examine the current evidence of ...
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Jakarta: University of Indonesia. Faculty of Medicine, 2016
610 IJIM 48:4 (2016)
Artikel Jurnal Universitas Indonesia Library
