Ditemukan 1 dokumen yang sesuai dengan query
Arum Prasetyaningtyas
"
Gabapentin, an anticonvulsant drug is used in the treatment of epilepsy, which has small dose therapeutic in blood plasma. Therapeutic drug monitoring (TDM) needs sensitive and specific analytical method.
The aim of this study was to obtaine optimized method for analytical gabapentine in plasma (in vitro) with High Performance Liquid Chromatography - fluorescence and validation the method. The method involves derivatization of the primary amine group of gabapentin with dansyl chloride produce flurescence agent and could ...
"
Depok: Fakultas Farmasi Universitas Indonesia, 2007
T39541
UI - Tesis Membership Universitas Indonesia Library