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"Latar belakang. Dislipidemia merupakan salah satu faktor resiko berkembangnya gagal jantung dan telah menjadi masalah kesehatan diseluruh dunia. Penelitian mengenai hubungan dislipidemia dan penyakit jantung belum banyak dilakukan di Indonesia.Tujuan. Mengetahui karakteristik pasien gagal jantung akut dan mengidentifikasi hubungan antara riwayat dislipidemia dengan mortalitas pasien gagal jantung akut selama perawatan.Metode. Penelitian dilakukan dengan desain potong lintang serta menggunakan 268 data sekunder dari studi Acute Decompensated Heart Failure Registry (ADHERE) di lima rumah sakit di Indonesia pada bulan Desember 2005 - 2006.Hasil. Pasien gagal jantung akut dalam penelitian ini dibagi kedalam dua kelompok. Kelompok pertama merupakan pasien dengan dislipidemia (88,8% dan kelompok kedua meupakan pasien tanpa dislipidemia (12,2%). Angka mortalitas pada kelompok pertama mencapai 3,0% dan pada kelompok kedua 0%. Melalui analisis bivariat tidak didapatkan hubungan bermakna antada riwayat dislipidemia dengan mortaitas pasien gagal jantung akut (p=0,603; OR: 0,828; CI: 0,101-6,759).Kesimpulan. Tidak terdapat hubungan bermakna antara riwayat dislipidemia dengan angka mortalitas gagal jantung akut selama perawatan di lima rumah sakit di Indonesia pada bulan Desember 2005 - 2006.

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Background. Dyslipidemia can promote the development of heart failure and has become one of global health problem. The study about associatin between dyslipidemia and in-hospital mortality of acute heart failure has never been done before in Indonesia.Objective. To define the characteristic of patient and to identify the association between dyslipidemia and in-hospital mortality of acute heart failure.Method. The design of this study was cross sectional with onsecutive sampling. This study used 976 acute heart failure patients from Acute Decompensated Heart Failure Registry (ADHERE) of 5 hospital in Indonesia from December 2005-2006.Result. Patiens with acute heart failure in this study were categorized in two groups. The first group was patients with dyslipidemia (88,8%) and the second was group wihout dyslipidemia (12,2%). The mortality rate of the first group was 3,0% and from the second was 0%. The bivariat analysis showed that there is no association between dyslipidemia and in-mortality of AHF patients (p=0,603; OR: 0,828; CI: 0,101-6,759).Conclusion. There is no significant association between Dyslipidemia and Inhospital Mortality of Acute Heart Failure in Five Hospital in Indonesia on December 2005 -2006."

"ABSTRAKSkripsi ini berisi tentang analisis tingkat risiko Penyakit Jantung Koroner (PJK) dengan metode perhitungan Framingham pada pegawai di BATAN – Serpong, Tahun 2011 - 2013. Penelitian ini bertujuan untuk melihat gambaran faktor dan tingkat risiko penyakit jantung koroner berdasarkan metode perhitungan Framingham. Merupakan penelitian non – desain khusus, berupa penelitian deskriptif. Hasil analisis tingkat risiko penyakit jantung koroner yang didapatkan, yaitu terdapat trend peningkatan faktor dan tingkat risiko berdasarkan metode perhitungan Framingham, dimana tingkat risiko penyakit jantung koroner pada pegawai tahun 2013 dalam kategori low risk sebesar 88,2%, intermediate risk sebesar 11,6% dan high risk sebesar 0,2%. Saran yang dapat diberikan yaitu diperlukannya promosi kesehatan yang terprogram dengan baik dalam mencegah penyakit jantung koroner di tempat kerja.

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ABSTRACTThis study is about risk level analysis of Coronary Heart Disease (CHD) using Framingham calculation method among workers at BATAN – Serpong, 2011-2013. The study aims to describe factors and risk level of coronary heart disease based on Framingham calculation method. Design of this study is descriptive. The result showed there were risk factor and risk level that trend increased based on Framingham method that showed that risk level of coronary heart disease among workers in 2013 have 88,2% low risk, 11,6% intermediate risk and 0,2 high risk. Suggestion that can be given based this result are managed health promotion programs to prevent coronary heart disease in the workplace."

"Intracoronary thrombosis plays an important role in the pathogenesis of acute coronary syndrome. It occurs due to a rupture of an atherosclerotic plaque, which may be spontaneous, as in the case of acute coronary syndrome, or due to procedures such as percutaneous intervention (PCI). Atherosclerotic plaque rupture causes exposure of thrombogenic subendothelial components and initiates platelet aggregation, which then initiates the coagulation cascade. In stable angina, the formation of platelet thrombus is the most important tiling to occur on plaque progressiveness as a result of rupture and episodic formation of thrombi.' Arterial thrombi contain many platelets. Anti-platelet agents are greatly beneficial in acute and chronic coronary heart disease. This paper discusses the use of anti-platelet agents in coronary heart disease."

"ABSTRAKLatar belakang : Perubahan gaya hidup pada masyarakat tersebut tentu saja mempengaruhi pergeseran pola penyakit dari penyakit infeksi ke penyakit degeneratif, diantaranya adalah penyakit jantung dan pembuluh darah. Prevalensi penyakit jantung dan pembuluh darah terus meningkat. Prevalensi obesitas juga mengalami peningkatan.Tujuan : Mengetahui hubungan obesitas dengan gangguan pada jantung di Indonesia (IFLS2014)Desain dan Hasil : Desain penelitian ini adalah studi cross sectional menggunakan data IFLS 5 tahun 2014. Hasil analisis menunjukkan bahwa ada hubungan antara obesitas dengan gangguan pada jantung di Indonesia (IFLS 2014) adjusted OR 1,349 (95% CI 1,087-1,675).Kesimpulan : Obesitas meningkatakan risiko terhadap gangguan pada jantung

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ABSTRACTBackground: Lifestyle changes in the community certainly affect the shift in patterns of disease from communicable diseases to uncommunicable (degenerative) diseases, including cardiovascular disease. The prevalence of cardiovascular disease continues to increase. The prevalence of obesity has also increased.Objective: To find out the aasociation between obesity and cardiovascular disease in Indonesia (IFLS2014)Design and Results: The design of this study was a cross sectional study using 5th IFLS 2014. The results of the analysis showed that there was an adsociaton between obesity and cardiovascular disease in Indonesia (2014 IFLS) adjusted OR 1.349 (95% CI 1.087-1.675).Conclusion: Obesity increases the risk of cardiovascular disease"