Hasil Pencarian  ::  Simpan CSV :: Kembali

"Latar Belakang: Pengawet dalam tetes mata memengaruhi permukaan okular, ditemukan terutama pada pasien yang menggunakan obat tetes anti-glaukoma. Beredar tetes mata timolol maleat dengan pengawet chlorhexidine gluconate (CHG) yang belum pernah diteliti efeknya terhadap parameter permukaan okular.Tujuan: Mengetahui pengaruh pengawet chlorhexidine gluconate 0,002% dalam sediaan timolol maleat 0,5% (timolol-CHG) terhadap permukaan okular pasien glaukoma dan hipertensi okuli.Metode: Penelitian eksperimental terandomisasi dengan samar tunggal pada 54 mata pasien dengan diagnosis glaukoma maupun hipertensi okuli yang menggunakan timolol maleat 0,5% pengawet polyquaternium-1 (timolol-PQ1) <12 bulan. Dua puluh tujuh mata mengganti pengobatan ke timolol-CHG dan 27 mata melanjutkan timolol-PQ1. Dinilai tear break up time (TBUT), tear break up pattern (TBUP), skor pewarnaan kornea konjungtiva (staining), skor ocular surface disease index (OSDI), Schirmer I dan TIO awal dan sesudah satu bulan intervensi.Hasil: Nilai rerata selisih TBUT 0,15±5,28 detik pada kelompok timolol-CHG dan (- 1,30)±3,47 pada timolol-PQ1. Tidak terdapat perbedaan bermakna selisih nilai parameter permukaan okular (TBUT, staining, OSDI, Schirmer I) maupun TIO antar kedua kelompok. Line dan dimple pattern merupakan TBUP yang paling banyak ditemukan pada kedua kelompok baik sebelum maupun sesudah intervensi. Analisis dalam kelompok mendapatkan penurunan TBUT bermakna (p < 0,05) pada kelompok timolol-PQ1 setelah dibandingkan dengan sebelum intervensi, pada kelompok timolol-CHG tidak didapatkan perbedaan bermakna.Kesimpulan: Timolol-CHG memiliki efek terhadap permukaan okular dan TIO sebanding dengan timolol-PQ1. Penggunaan timolol-CHG dapat dipertimbangkan sebagai alternatif jangka pendek pengobatan glaukoma.

---

Background: Patients with glaucoma and ocular hypertension using topical anti-glaucoma medication are more likely to have ocular surface problems. It happens mainly due to the preservatives in the eye drops. Chlorhexidine gluconate (CHG) as a preservative have not been studied for their effects on ocular surface parameters.

Objective: To evaluate the effect of chlorhexidine gluconate 0,002% preseved timolol maleate 0,5% (timolol-CHG) on the ocular surface of patients with glaucoma and ocular hypertension.

Methods: Randomized single-blind controlled trial in 54 eyes of patients diagnosed with glaucoma or ocular hypertension that has been using polyquaternium-1 preserved timolol maleate 0.5% (timolol-PQ1) for <12 months. Twenty-seven eyes switched therapy to timolol- CHG, and 27 eyes continued with timolol-PQ1. Tear break-up time (TBUT), tear break-up pattern (TBUP), corneal-conjunctival staining score, ocular surface disease index (OSDI) scoring, Schirmer I, and intraocular pressure (IOP) were assessed at baseline and one month post intervention.

Results: Mean differences (1 month-baseline) of TBUT were 0.15±5.28 seconds in timolol- CHG group and (-1.30)±3.47 in timolol-PQ1 group. There were no difference (p > 0.05, for all) between groups in terms of ocular surface parameters (TBUT, staining, OSDI, Schirmer I) and IOP mean differences. Line and dimple pattern were the most common break-up pattern found in both group at baseline and at 1 month. Analysis within group found significant difference (p < 0.05) of timolol-PQ1 TBUT at 1 month compared to baseline, TBUT were lower at 1 month.

Conclusion: Timolol-CHG has comparable effects on the ocular surface and IOP comparable to timolol-PQ1. The use of timolol-CHG may be considered as a short-term alternative for glaucoma treatment."

"ABSTRACTTujuan: Menilai keamanan injeksi intrakamera levofloksasin 0,5 sediaan tetes mata dosis tunggal 0,6 mL steril tanpa pengawet pada hewan coba kelinci. Desain: Penelitian ini merupakan uji eksperimental dengan desain paralel, acak, tersamar terhadap hewan coba kelinci albino New Zealand White . Metode: Dua puluh empat mata dari dua belas ekor kelinci dibagi kedalam ketiga kelompok, kelompok pertama LFX mendapat perlakuan injeksi intrakamera levofloksasin 0,5 sediaan tetes mata dosis tunggal steril tanpa pengawet 0,6 mL n = 6 , kelompok kedua CRAV mendapat injeksi intrakamera levofloksasin 0,5 sediaan tetes mata botol 5 mL n = 6 dan kelompok ketiga BSS mendapat balanced salt solution intrakamera sebagai kontrol n = 12 . Hasil: Skor klinis pada hari 1, 3, 5, dan 7 tidak menunjukkan adanya perbedaan antara ketiga kelompok. Perubahan klinis maksimal yang ditemukan berupa kekeruhan kornea ringan serta sel dan flare ringan dalam bilik mata depan. Pemeriksaan histopatologi tidak menunjukkan adanya perbedaan statistik kelainan akibat efek toksik yang signifikan pada semua kelompok. Vakuolisasi endotel ditemukan pada semua kelompok sehingga tidak signifikan sebagai perubahan akibat efek toksik. Kesimpulan: Injeksi intrakamera 0,1 mL levofloksasin 0,5 dalam sediaan tetes mata dosis tunggal 0,6 mL steril tanpa pengawet memiliki keamanan yang sama dengan sediaan tetes mata botol 5 mL tanpa pengawet pada mata hewan coba kelinci dalam hal perubahan klinis dan histopatologis."

---

""ABSTRACT"Purpose To evaluate the safety of intracameral injection of levofloxacin 0,5 eye drop single dose 0,6 mL preservative free LFX on rabbit eye. Methods This was an experimental, pararel, and randomized study. Twenty four eyes of twelve New Zealand White rabbit were divided to three groups. First group LFX were treated with 0,1 mL intracameral injection levofloxacin 0,5 eye drop single dose 0,6 mL preservative free n 6 , second group CRAV were treated with 0,1 mL intracameral levofloxacin 0.5 eye drop bottle 5 mL preservative free n 6 , and third group BSS were treated with 0,1 mL intracameral injection balanced salt solution n 12 . The clinical evaluation was performed on day 1st, 3rd, 5th and 7th. Each eye was enucleated on day 7th and underwent histopathology examination. Results The clinical scores among three groups did not show any significant difference on day 1st, 2nd, 3rd, and 7th p 0.05 . Mild corneal opacity, mild cells and flares in anterior chamber were the only noted in clinical scores. Histopathology score demonstrated no statistically significant difference between three groups p 0.05 . Vacuolization of corneal endothelial cells were notes in all groups, but not statistically significant.Conclusion Intracameral injection of levofloxacin 0.5 eye drop single dose 0.6 mL preservative free was safe to rabbit eye, in clinical and histopathology scores, similar with levofloxacin 0.5 eye drop bottle 5 mL preservative free"

"Perkembangan terapi adjuvan pada glaukoma untuk memperlambat progresi glaukoma saat ini terus dieksplorasi. Penelitian ini mengevaluasi efek Mirtogenol, pada perubahan perfusi okular (perfusi kapiler dan flux index), ketebalan lapisan serabut saraf retina (LSSR), dan tekanan intraokular (TIO) pada pasien glaukoma primer sudut terbuka (GPSTa) yang menerima terapi timolol maleat 0,5% tetes mata. Penelitian ini merupakan uji klinis acak terkontrol tersamar ganda. Terdapat 36 subjek (37 mata) dengan GPSTa dan TIO < 21 mmHg yang diacak untuk mendapatkan Mirtogenol atau plasebo selama 8 minggu. Kedua grup dibandingkan, pada kelompok Mirtogenol, rata-rata peningkatan perfusi kapiler dan flux index lebih baik, dan pada kuadran superior terdapat hasil yang signifikan secara statistik setelah 4 minggu (p=0.018). Rerata perbedaan ketebalan LSSR di seluruh kuadran terdapat penurunan dengan nilai yang lebih sedikit pada kelompok Mirtogenol (p>0.05). Penurunan TIO yang konsisten pada kelompok Mirtogenol setelah 8 minggu (p>0.05). Ditemukan efek samping pada 1 subjek yaitu gangguan lambung. Suplementasi Mirtogenol, sebagai terapi adjuvan pada pengobatan glaukoma dapat meningkatkan perfusi okular, mempertahankan ketebalan LSSR, dan menurunkan TIO.

---

The development of adjuvant therapies in glaucoma to slow its progression is currently being explored. This study evaluates the effects of Mirtogenol on changes in ocular perfusion (capillary perfusion and flux index), retinal nerve fiber layer (RNFL) thickness, and intraocular pressure (IOP) in primary open-angle glaucoma (POAG) patients receiving 0.5% timolol maleate eye drops. This study is a double-blind, randomized controlled clinical trial. There were 36 subjects (37 eyes) with POAG and IOP < 21 mmHg randomized to receive Mirtogenol or placebo for 8 weeks. Compared between the two groups, the Mirtogenol group showed a better average improvement in capillary perfusion and flux index, with statistically significant results in the superior quadrant after 4 weeks (p=0.018). The mean difference in RNFL thickness across all quadrants showed a smaller reduction in the Mirtogenol group (p>0.05). There was a consistent decrease in IOP in the Mirtogenol group after 8 weeks (p>0.05). One subject experienced side effects, specifically stomach disturbances. Mirtogenol supplementation, as an adjuvant therapy in glaucoma treatment, can improve ocular perfusion, maintain RNFL thickness, and reduce IOP."

"[ABSTRAKTujuan : Mengevaluasi ada tidaknya perbedaan kualitas air mata pada penderita glaukoma yangmengalami mata kering antara yang diberi tetes mata sodium hialuronat 0,1% mengandung bahanpengawet benzalkonium klorida dan tetes mata sodium hialuronat 0,1% tanpa bahan pengawet.Metode : Penelitian ini merupakan penelitian prospektif terandomisasi. 30 pasien glaukoma yangmengalami mata kering dirandomisasi ke dalam kedua kelompok. Kelompokpertama,mendapatkan obat tetes mata artificial tear mengandung sodium hialuronat 0,1% denganpengawet benzalkonium klorida, sedangkan kelompok II, mendapatkan obat tetes mata artificialtear mengandung sodium hialuronat 0,1% tanpa pengawet selama 1 bulan. Pemeriksaan Schirmertest, TFBUT, OPI, dan sitologi impresi dilakukan pada kedua kelompok baik sebelum dan sesudah1 bulan penetesan obat tetes mata artificial tear.Results: Nilai median sitologi impresi sel goblet pasca penetesan artificial tear meningkat padakelompok I (118,15-485) dan kelompok II (67.0-200), namun secara statistik tidak ada perbedaanbermakna. Nilai rata ? rata TFBUT pasca penetesan pada kelompok I (14,45±7,85) dan kelompokII (13,91±7,46) meningkat dibandingkan sebelum penetesan, serta secara statitstik memilikiperbedaan yang bermakna. Nilai Schirmer test dan OPI pasca penetesan pada kedua kelompokmengalami peningkatan secara klinis dibandingkan sebelum penetesan, namun tidak terdapatperbedaan bermakna secara statistik.Conclusions : Pemberian artificial tear mengandung sodium hialuronat 0,1% baik denganpengawet maupun tanpa pengawet selama 1 bulan memberikan peningkatan Schirmer test,TFBUT,OPI dan sitologi impresi sel goblet.

---

ABSTRACTObjectives: To evaluate the difference of quality of tears between glaucoma patients sufferingfrom dry eyes treated with 0.1% sodium hyaluronat eyedrops with preservativebenzalconiumchloride and those treated with 0.1% sodium hyaluronat eyedrops withoutpreservative.Methods: This is a randomized prospective study. Subjects were 30 glaucoma patients sufferingfrom dry eyes, whom later randomized into two groups. Group I was treated with artificial tearseye drops, which contained 0.1% sodium hyaluronat and benzalconium chloride preservative,whereas Group II was treated with artificial tears eye drops, which contained 0.1% sodiumhyaluronat without preservative for one-month duration. Before and after the treatment withartificial tears eyedrops, subjects of both groups were tested with Schirmer test, TFBUT, OPI, andimpression cytology.Results: The median of goblet cells in impression cytology after treatment with artificial tears eyedrops increased in group I (118, 15 ? 485) and group II (67, 0 ? 200), even though not statisticallysignificant. Mean TFBUT after treatment was also higher in Group I (14.45±7.85) and Group II(13.91±7.46), yet not statistically significant. Schirmer test and OPI results after treatment showeda clinical improvement in both groups, however no statistic result was found to be significant.Conclusions: Treatment with artifical tears eye drops containing 0.1% sodium hyaluronat with orwithout preservative for one month will improve Schirmer test, TFBUT, OPI, and goblet cellsimpressions cytology result on glaucoma patients suffering from dry eyes.;Objectives: To evaluate the difference of quality of tears between glaucoma patients sufferingfrom dry eyes treated with 0.1% sodium hyaluronat eyedrops with preservativebenzalconiumchloride and those treated with 0.1% sodium hyaluronat eyedrops withoutpreservative.Methods: This is a randomized prospective study. Subjects were 30 glaucoma patients sufferingfrom dry eyes, whom later randomized into two groups. Group I was treated with artificial tearseye drops, which contained 0.1% sodium hyaluronat and benzalconium chloride preservative,whereas Group II was treated with artificial tears eye drops, which contained 0.1% sodiumhyaluronat without preservative for one-month duration. Before and after the treatment withartificial tears eyedrops, subjects of both groups were tested with Schirmer test, TFBUT, OPI, andimpression cytology.Results: The median of goblet cells in impression cytology after treatment with artificial tears eyedrops increased in group I (118, 15 – 485) and group II (67, 0 – 200), even though not statisticallysignificant. Mean TFBUT after treatment was also higher in Group I (14.45±7.85) and Group II(13.91±7.46), yet not statistically significant. Schirmer test and OPI results after treatment showeda clinical improvement in both groups, however no statistic result was found to be significant.Conclusions: Treatment with artifical tears eye drops containing 0.1% sodium hyaluronat with orwithout preservative for one month will improve Schirmer test, TFBUT, OPI, and goblet cellsimpressions cytology result on glaucoma patients suffering from dry eyes., Objectives: To evaluate the difference of quality of tears between glaucoma patients sufferingfrom dry eyes treated with 0.1% sodium hyaluronat eyedrops with preservativebenzalconiumchloride and those treated with 0.1% sodium hyaluronat eyedrops withoutpreservative.Methods: This is a randomized prospective study. Subjects were 30 glaucoma patients sufferingfrom dry eyes, whom later randomized into two groups. Group I was treated with artificial tearseye drops, which contained 0.1% sodium hyaluronat and benzalconium chloride preservative,whereas Group II was treated with artificial tears eye drops, which contained 0.1% sodiumhyaluronat without preservative for one-month duration. Before and after the treatment withartificial tears eyedrops, subjects of both groups were tested with Schirmer test, TFBUT, OPI, andimpression cytology.Results: The median of goblet cells in impression cytology after treatment with artificial tears eyedrops increased in group I (118, 15 – 485) and group II (67, 0 – 200), even though not statisticallysignificant. Mean TFBUT after treatment was also higher in Group I (14.45±7.85) and Group II(13.91±7.46), yet not statistically significant. Schirmer test and OPI results after treatment showeda clinical improvement in both groups, however no statistic result was found to be significant.Conclusions: Treatment with artifical tears eye drops containing 0.1% sodium hyaluronat with orwithout preservative for one month will improve Schirmer test, TFBUT, OPI, and goblet cellsimpressions cytology result on glaucoma patients suffering from dry eyes.]"

"ABSTRAKIsometric Handgrip Exercise merupakan salah satu terapi non farmakologis yang dikembangkan untuk menurunkan tekanan darah pasien hipertensi. Penelitian ini bertujuan untuk mengidentifikasi pengaruh isometric handgrip exercise terhadap perubahan tekanan darah pasien hipertensi. Desain penelitian quasi experiment dengan pendekatan control group pretest posttest design pada 44 responden meliputi kelompok kontrol dan kelompok intervensi. Kelompok intervensi mendapatkan latihan handgrip selama 3 menit, sekali sehari dan dilakukan selama 5 hari. Kedua kelompok dilakukan pengukuran tekanan darah sebelum dan setelah latihan pada hari 1 dan ke 5. Hasil penelitian menunjukkan bahwa ada pengaruh isometric handgrip exercise (IHG) terhadap perubahan tekanan darah pasien hipertensi. kesimpulan penelitian ini adalah isometric handgrip exercise secara bermakna dapat menurunkan tekanan darah sistolik dan tekanan darah diastolik. Hasil penelitian ini diharapakan menjadi dasar isometric handgrip exercise (IHG) sebagai intervensi keperawatan yang mandiri dan inovatif pada asuhan keperawatan klien dengan hipertensi

---

ABSTRACTAn Isometric Handgrip Exercise is one of the non-pharmacological therapies that is developed to lower blood pressure in hypertensive patients. The aim of the study was to identify the effect of isometric handgrip exercise on changes in blood pressure in hypertensive patients. A Quasi experimental research design approach pretest posttest control group design was employed with 44 respondents included control and intervention groups. The intervention group got handgrip exercise for 3 minutes, once a day and performed for 5 days. Both groups performed measurements of blood pressure before and after exercise on days 1 and 5. The results showed that there is influence of isometric handgrip exercise on changes in blood pressure in hypertensive patients. Conclusion of this study is the isometric handgrip exercise (IHG) can significantly lower systolic blood pressure and diastolic blood pressure. The result of this study recommended that isometric handgrip exercise (IHG) can bean independen and innovative therapeutic nursing intervension in nursing care of patients with hypertension."

"Latar belakang: Manifestasi okular pada psoriasis sering tidak disadari baik oleh dokter maupun pasien. Kelainan mata disebabkan oleh predisposisi genetik, invasi lesi kulit, reaksi autoimun, peradangan sistemik, atau efek samping pengobatan pada psoriasis. Secara global, manifestasi okular berkisar antara 10–80%, dengan kasus berat dapat menyebabkan kerusakan penglihatan permanen. Meskipun demikian, skrining mata belum secara resmi direkomendasikan dalam alur tata laksana psoriasis di Indonesia. Instrumen sederhana, misalnya daftar tilik, penting dalam mendeteksi dini dan merujuk ke dokter spesialis mata (Sp.M) guna mencegah kerusakan okular yang permanen. Penelitian ini bertujuan membuat instrumen daftar tilik yang valid, reliabel, dan sensitif untuk mempermudah skrining kelainan mata pada psoriasis.Metode: Penelitian ini terdiri atas 2 tahap. Tahap pertama penyusunan instrumen daftar tilik berdasarkan gejala subjektif dan objektif kelainan mata pada psoriasis vulgaris, yang diberikan masukan melalui focus group discussion oleh ahli di bidang dermatologi venereologi dan estetika serta mata. Pasien psoriasis vulgaris yang berobat di Poliklinik Dermatologi dan V enereologi RSUPN dr. Cipto Mangunkusumo, diperiksa menggunakan instrumen daftar tilik oleh dokter spesialis Dermatologi Venereologi dan Estetika (Sp.D.V.E). Kemudian seluruh subjek penelitian (SP) dilakukan pemeriksaan mata lengkap oleh dokter Sp.M, untuk mengonfirmasi hasil pemeriksaan sebagai baku emas. Hasil data dianalisis untuk mendapatkan nilai validitas, reliabilitas, dan sensitivitas instrumen daftar tilik.Hasil: Sebanyak 60 SP mengikuti penelitian ini. Instrumen daftar tilik yang dihasilkan memiliki validitas, reliabilitas, dan sensitivitas baik, dengan koefisien korelasi Pearson 0,771 (>0,7) nilai p <0,05, Cronbach α 0,712 untuk pemeriksaan Sp.D.V.E dan 0,721 pada pemeriksaan oleh Sp.M, serta interclass correlation coefficient (ICC) 0,801, serta sensitivitas 94%. Prevalensi kelainan mata yang ditemukan sebesar 84,17% dengan urutan terbanyak yaitu meibomian gland dysfunction (MGD), dry eye, dan katarak. Kelainan mata lainnya berupa glaukoma dan blefaritis juga ditemukan, namun tidak terdapat SP dengan konjungtivitis.Kesimpulan: Instrumen daftar tilik valid, reliabel, dan sensitif dalam mendeteksi dini kelainan mata pada psoriasis.

---

Background: Ocular manifestations in psoriasis often go unnoticed by both doctors and patients. These manifestations may arise from genetic predisposition, skin lesion invasion, autoimmune responses, systemic inflammation, or adverse effects of psoriasis treatment. Globally, ocular manifestations in psoriasis range from 10% to 80%, with severe cases causing permanent vision impairment. Despite these implications, ocular screening is not officially recommended in Indonesian psoriasis treatment guidelines. Simple instruments, such as a checklist, are crucial in early detection and referral to ophthalmologist. This study aims to develop a valid, reliable, and sensitive checklist instrument to facilitate screening for ocular abnormalities in psoriasis.

Methods: This study consists of two phases. The first phase involves the development of a checklist instrument based on subjective and objective ocular symptoms in psoriasis vulgaris, with input from focus group discussions with experts in dermatovenereology and ophthalmology. Psoriasis vulgaris patients treated at the Dermatology and Venereology Clinic of the National General Hospital dr. Cipto Mangunkusumo underwent eye examinations using the checklist instrument conducted by dermatovenereologist. Subsequently, ophthalmologists performed comprehensive eye examinations on all participants to confirm results as the gold standard. Data were analyzed for validity, reliability, and sensitivity of the checklist instrument.

Results: Sixty subjects participated, with checklist instrument demonstrates good validity, reliability, and sensitivity, with a Pearson correlation coefficient of 0.771 (>0.7), p-value <0.05, Cronbach’s α of 0.712 for examinations by dermatovenereologist and 0.721 for ophthalmologists, as well as an interclass correlation coefficient (ICC) of 0.801, and a sensitivity of 94%. The prevalence of eye disorders found in this study is 84,17%, with the most common eye disorders being meibomian gland dysfunction (MGD), dry eye, and cataracts. Glaucoma and blepharitis were also identified, but no subjects had conjunctivitis.

Conclusion: The checklist instrument is valid, reliable, and sensitive in the early detection of ocular manifestation in psoriasis."

"[Penelitian ini merupakan uji klinis acak tersamar yang bertujuan membandingkan efektivitas dan keamanan obat Kombinasi Tetap Timolol 0,5%-Brinzolamide 1% (KT-TB) dengan Kombinasi Tetap Timolol 0,5%-Latanoprost 0,005% (KT-TL) Preservative free pada pasien glaukoma primer sudut terbuka (GPSTa) yang tidak terkontrol dengan Timolol 0,5%. Sebanyak 42 pasien GPSTa dibagi secara acak menjadi dua kelompok. Hasil penelitian mendapatkan bahwa KT-TL preservative free memiliki kemampuan yang lebih besar dalam menurunkan TIO dibandingkan KT-TB. Keduanya mampu mempertahankan rentang TIO diurnal < 3 mmHg. Efek samping tersering yang ditemukan pada kedua obat adalah hiperemi konjungtiva, dengan efek samping multipel lebih terkait dengan pmeberian obat KT-TB, This is a prospective, randomized clinical trial. The purpose of this study were to compare the efficacy and safety of fixed-combination Timolol 0.5%/Latanoprost 0.005% (TL-FC) preservative free and fixed-combination Timolol 0.5%-Brinzolamide 1% (TB-FC) in POAG patients transitioned frome Timolol 0.5% monoterapi. Fourty two POAG patienst were divided randomly into 2 groups. The result of this study were TL-FC preservative free has a greater effect in lowering IOP than TB-FC. Both treatment can controlled the diurnal IOP range under 3 mmHg. The most common ocular AEs was hyperemia conjunctiva. Multiple subjective AEs were more related to TB-FC]"

"Lansia hipertensi merupakan kelompok rentan (vulnerable) karena adanya perubahan fisiologis sistem kardiovaskuler, keterbatasan sumber daya ekonomi, gaya hidup tidak sehat dan berbagai kejadian kehidupan seperti kehilangan pasangan serta meningkatnya prevalensi hipertensi dari tahun 2007 sebesar 7,2% menjadi 9,4% pada tahun 2013. Penulisan Karya Ilmiah Akhir ini bertujuan untuk mengetahui pengaruh intervensi MANSET HT terhadap pengendalian hipertensi pada lansia dengan menggunakan integrasi model teori manajemen, Community as Partner, Familiy Centered Nursing, dan Self Care Activity. Besar sampel 30 lansia dengan hipertensi. Intervensi selama 9 bulan terdiri dari kombinasi relaksasi meditasi, olahraga, relaksasi otot progresif dan pengaturan diet hipertensi. Hasil uji statistik terjadi penurunan tekanan darah yang signifikan (p value 0,000). Intervensi terbukti efektif sehingga direkomendasikan sebagai salah satu program pembinaan kesehatan lansia secara berkelanjutan oleh Dinas Kesehatan dan Puskesmas melalui program perawatan kesehatan masyarakat.

---

Elderly with hypertension is one of the vulnerable groups. The factors that influence the vulnerability in elderly with hypertension consist of cardiovascular system changes due to the aging process, the economic resources, unhealthy lifestyle and life events such as loss of partner. The prevalence of hypertension in Indonesia increased from 7.2% in 2007 to 9.4% in 2013. The purpose of this study was asses the effect of the intervention MANSET HT to control hypertension in the elderly using the integration model of management theory, the community as a partner, familiy centered nursing, and self-care activity. MANSET HT intervention was conducted on 30 elderlies with hypertension for 9 months consisted of a combination of relaxation meditation, exercise, progressive muscle relaxation and hypertension diet management. Statistical test results showed a significant decrease in blood pressure after the intervention (p value 0.000). This intervention was effective to control the hypertension. It is recommended that elderly health coaching program development should be done in a sustainable manner in the ministry of health and community health center by community nursing cara programme."

"ABSTRAKSEFT termasuk teknik relaksasi mind-body therapy, merupakan teknik penggabungan dari sistem energi tubuh (energy medicine) dan terapi spiritual dengan menggunakan metode tapping pada beberapa titik tertentu pada tubuh. SEFT dapat membantu individu bebas dari tekanan emosional (energi negatif), yang mana merupakan penyebab meningkatnya tekanan darah pada pasien hipertensi. Tujuan penelitian ini untuk mengidentifikasi pengaruh terapi SEFT terhadap penurunan tekanan darah pasien hipertensi. Penelitian ini menggunakan desain kuasi eksperimen dengan pendekatan the one group pretest – posttest. Hasil analisis data menunjukkan ada pengaruh terapi SEFT terhadap tekanan darah pasien hipertensi. Faktor karakteristik umur, jenis kelamin, riwayat penyakit keluarga dan penyakit penyerta tidak ada hubungan dengan penurunan tekanan darah setelah terapi SEFT. Hasil penelitian ini diharapkan menjadi dasar terapi SEFT sebagai intervensi keperawatan yang mandiri dan inovatif pada asuhan keperawatan klien dengan hipertensi.

---

ABSTRACTSEFT as one of the relaxation techniques of mind-body therapy, is a combination technique of the body's energy system (energy medicine) and spiritual therapy using tapping on certain points of the body. SEFT can helps individual free from emotional distress (negative energy), which is one of the causes of increased blood pressure in patients with hypertension. The purpose of this study was to identify the effect of SEFT therapy on blood pressure in patients with hypertension. This study used a quasi-experimental design with a one-group pretest – posttest approach. The results of data analysis showed that there is significant effect of SEFT therapy on reduction of blood pressure in patients with hypertension. Characteristics of age, gender, family history of disease and comorbidities are not related to the decrease in blood pressure after SEFT therapy. The results of this study recommended that the SEFT therapy can be an independent and innovative therapeutic nursing intervention in nursing care of patients with hypertension."

"Slow deep breathing (SDB) adalah tindakan nonfarmakologis untuk menurunkan tekanan darah pasien hipertensi primer. Penelitian ini bertujuan untuk mengetahui efektifitas SDB terhadap penurunan tekanan darah pasien hipertensi primer. Metode penelitian ini menggunakan desain Randomized Clinical Trial dengan pretest dan post test control group. Sampelnya 142 responden, meliputi 33 responden kelompok rendah garam (RG), 37 responden kelompok SDB, 39 responden kombinasi kelompok SDB dan RG; dan 33 responden kelompok kontrol. Sampel diambil dengan cara randomisasi. Hasil penelitian menunjukan penurunan tekanan darah secara bermakna terutama pada kelompok SDB. Tekanan darah sistolik menurun 28,59 mmHg (P value=0,002) dan tekanan darah diastolik 16,92 mmHg (P value=0,007). Analisis dengan uji Tukey diketahui tekanan darah sistolik yang berbeda secara bermakna yaitu antara SDB dan kelompok kontrol (P value=0,001). Tekanan darah diastolik yang berbeda secara bermakna, yaitu: RG dan SDB-RG (P value=0,046); RG dan kelompok kontrol (P value=0,003); SDB dan SDB-RG (P value=0,038) serta SDB dan kelompok kontrol (P value=0,005). Penelitian ini merekomendasikan penerapan SDB untuk membantu menurunkan prevalensi hipertensi sehingga meminimalkan komplikasi yang mungkin timbul.

---

Slow deep breathing is a nonpharmacology therapy to reduce blood pressure in patients with primary hypertension. The purpose of this study was to determine the effectiveness of slow deep breathing exercise to reduce blood pressure in patients with primary hypertension in Atambua East Nusa Tenggara. The method of this research was a quantitative research: a randomized clinical trial design with pretest and post test control group. The sample was 142 respondents, which consisted of 33 respondents in the lower salt (RG) group, 37 respondents in the slow deep breathing (SDB) group, 39 respondents in the combination of SDB-RG group; and 33 respondents in the control group. The method of sampling used a randomization.

The results showed that there were differences in the reduction of systolic blood pressure in SDB group for 28.59 mm Hg and diastolic blood pressure for 16.92 mmHg. The result of Anova analysis showed that there was a significant decrease on average of systolic blood pressure (p = 0.002) and diastolic blood pressure (p = 0.007). Further analysis by Tuckey test of systolic blood pressure found that between SDB group and control group were significantly different, however the other groups was not significant. (P = 0.001). After undergoing further Tukey analysis we found that the systolic blood pressure of four groups has significant differences. The SDB and controlling groups have P value=0,001 differences. RG and the controlling groups have P value=0,003 differences. SDB and SDB-RG groups have P value=0,038 differences. And SDB and controlling groups have P value=0,005 differences. This research would like to suggest applied non-pharmacological actions particularly toward SDB groups in order to decrease the prevalence of hypertension. This will minimize consequences caused by this problem."