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Nasytha Vikarina
"Latar Belakang: Sumber infeksi dalam rongga mulut berasal dari periodontium, periapikal dan pulpa. Apabila bakteri tersebut masuk ke pembuluh darah, maka bakteri atau toksik yang dihasilkan bakteri tersebut dapat memasuki aliran darah dan mengikuti sirkulasi arteri menuju jantung. Tujuan: mengetahui fokus infeksi rongga mulut rujukan Divisi Jantung ke Divisi Penyakit Mulut Rumah Sakit Cipto Mangunkusumo tahun 2010-2012 dengan melihat oral hygiene, DMF-T, kalkulus dan penyakit periodontal pada 227 rekam medik pasien. Metode: penelitian deskriptif menggunakan data sekunder. Hasil: 162 pasien memiliki oral hygiene buruk dan 124 pasien menderita gingivitis dan periodontitis. Kesimpulan: Bakteri pada rongga mulut dapat menjadi fokus infeksi pada pasien jantung

Background: The source of infection in the oral cavity has come from the periodontium, periapical and pulp. When the bacteria enters into the bloodvessels, the bacteria or toxic substances which produced by bacteria may enter the bloodstream and follow the arterial circulation towards the heart. Objective: To recognize the focus of infection of the oral cavity referral from Division of Cardiovascular to Division Oral Medicine in Rumah Sakit Cipto Mangunkusumo between 2010-2012 to see oral hygiene, DMF-T, calculus and periodontal disease in 227 medical records of cardiac patients. Methodes: This descriptive study using secondary data, which is the medical records of cardiac patient. Results: 162 patients had poor oral hygiene and 124 patients suffered from gingivitis and periodontitis. Conclusion: Bacteria in the oral cavity could be a focus of infection in cardiac patients."
Jakarta: Fakultas Kedokteran Gigi Universitas Indonesia, 2012
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UI - Skripsi Membership  Universitas Indonesia Library
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Annisa Ghaisani
"ABSTRAK
Latar Belakang: Periodontitis merupakan suatu penyakit inflamatori kronis pada jaringan periodonsium yang masih menjadi masalah besar dalam bidang kedokteran gigi. Periodontitis dapat menyebabkan kerusakan jaringan gingiva, ligamen periodontal, dan tulang alveolar yang progresif, yang secara klinis ditandai dengan adanya kehilangan perlekatan gingiva dan perubahan tinggi tulang alveolar, sehingga dibutuhkan suatu model periodontitis yang sederhana, terstandar, dan terkendali untuk pendekatan pencegahan dan terapi dalam mengatasi masalah ini. Lipopolisakarida LPS terbukti dapat menginduksi terjadinya periodontitis secara terstandar. Tujuan: Membuat model kerusakan tulang alveolar periodontitis pada anterior mandibula tikus Wistar yang sederhana, terstandar, dan terkendali. Metode: Periodontitis diinduksi dengan injeksi LPS konsentrasi 200mg, 500mg, dan 750mg dalam 200ml larutan saline ke dalam gingiva mandibula tikus Wistar pada regio papilla interdental antara gigi insisif mandibula. Tikus Wistar dibunuh pada hari ketujuh, kemudian mandibula didiseksi dan jaringan lunak dipisahkan dari jaringan keras untuk dilakukan pengamatan dengan Stereomikroskop. Hasil: Kerusakan tulang terbesar terjadi pada injeksi LPS konsentrasi 200mg dalam 200ml larutan saline dengan rata-rata penurunan tinggi tulang yaitu 2,243mm. Kesimpulan: Injeksi LPS dengan konsentrasi 200mg dalam 200ml larutan saline pada jaringan periodontal regio anterior mandibula tikus Wistar dapat menyebabkan kerusakan tulang alveolar dan dapat menjadi acuan untuk pembuatan model periodontitis yang terstandar.

ABSTRACT
Background Periodontitis is a chronic inflammatory disease of the periodontium that remains a major problem in the field of dentistry. Periodontitis can cause progressive destruction of gingival tissue, periodontal ligament, and alveolar bone, which is clinically characterized by loss of gingival attachment and alveolar bone height reduction. Therefore, a simple, standardized, and controlled model of periodontitis is required for a preventive and therapeutic approach to overcome this problem. Lipopolysaccharide LPS has been shown to induce the occurrence of standardized periodontitis. Aim To create a model of alveolar bone destruction periodontitis in mandibular anterior region of Wistar rat which is simple, standardized, and controlled. Methods Periodontitis was induced by injection of 200 g, 500 g, and 750 g LPS in 200 l saline solution into mandibular gingiva of Wistar rat in the interdental papilla region between the mandibular incisors. Wistar rats were killed on the seventh day, then the mandible was dissected and the soft tissue was separated from the hard tissue for Stereomicroscopic observation. Results The highest bone loss occurred at injection of 200 g LPS in 200 l saline solution with an average height of bone loss is 2.243mm. Conclusion Injection of 200 g LPS in 200 l saline solution into the periodontal tissue of mandibular anterior of Wistar rat may cause alveolar bone destruction and may be used as a reference to make a standardized model of periodontitis."
2018
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UI - Skripsi Membership  Universitas Indonesia Library
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Vania Aramita Sari
"ABSTRAK
Fungsi bicara adalah tujuan utama palatoplasty, namun tidak terdapat evaluasi jangka panjang untuk fungsi bicara pada rumah sakit kami yang merupakan rumah sakit rujukan nasional yang memiliki pusat sumbing dan kraniofasial satu-satunya di Indonesia. Studi ini bertujuan untuk mendapatkan data awal dengan evaluasi fungsi bicara pasien pasca palatoplasty antara Oktober 2010-Desember 2012 dengan kata asesmen persepsual teradaptasi berbahasa indonesia, dan menjabarkan faktor yang mempengaruhi fungsi bicara. Dua puluh tiga total sampel diukur untuk tingkat artikulasi di mana 17 (74%) pasien memiliki produksi normal dari mayoritas fonem, dan 6 (26%) pasien memilki distorsi predominan dari fonem. Penilaian hipernasalitas normal pada 12 (52%) pasien, ringan pada 5 (22%) pasien dan sedang pada 6 (26%) pasien. Penilaian inteligibilitas suara secara dominan normal di mana semua kata dapat dimengerti pada 17 (74%) patients dan sisanya yaitu 6 (26%) pasien membutuhkan perhatian pendengar. Kemampuan velofaringeal baik pada 16 (70%) pasien, sedang pada 1 (4%) pasien dan buruk pada 6 (26%) pasien.

ABSTRACT
Speech is the primary goal of palatoplasty, however, there is no current data available about the long term speech evaluation after palatoplasty in our hospital which is the national referral hospital that has the only cleft craniofacial center in Indonesia. The initial data of speech outcome is required for further research which assessment should be standardized and applicable to Indonesian children that mostly speak bahasa. This study aims to get initial data by evaluating speech outcome of patients that underwent palatoplasty between October 2010-December 2012 with adapted perceptual assessment words in Indonesian language, and describe factors influencing speech. Total 23 samples were measured for articulation rating where 17 (74%) patients had normal production of majority of phonemes, while there were 6 (26%) patients had predominantly distortion of phonemes. The hypernasality rating were normal in 12 (52%) patients, mild in 5 (22%) patients and moderate in 6 (26%) patients. The speech intelligibility rating were dominantly normal which all speech is understood in 17 (74%) patients and the rest of 6 (26%) patients were listeners attention needed. The velopharyngeal competence were good in 16 (70%) patients, fair in 1 (4%) patients and poor in 6 (26%) patients.

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2018
SP-Pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Hananto Anggoro Wiryawan
"Latar belakang: Tatalaksana rekonstruksi pada pasien reseksi mandibula dengan hanya menggunakan rekonstruksi plat umum dilakukan dibeberapa rumah sakit di Indonesia. Beberapa komplikasi yang dapat terjadi pasca rekonstruksi mandibula dapat berupa ekspose plat, fraktur plat dan fistula.
Tujuan: Tujuan penelitian ini akan mencari beberapa faktor yang mempengaruhi terjadinya komplikasi tersebut.
Material dan metode: Penelitian ini merupakan studi retrospektif dari tahun 2012-2017 yang diambil dari rekam medis. Data tumor jinak mandibula (lokasi, ukuran, panjang), data sistemik pasien (riwayat merokok, diabetes, status gizi) dan data operasi (durasi, sistem plat rekonstruksi) dihubungkan dengan kejadian komplikasi yang dianalisis dengan menggunakan Kaplan Meier Survival Curve dan Cox Regresi Proportional Hazard.
Hasil: Terkumpul 69 data dengan prevalensi terjadinya komplikasi sebesar 21,73%(15/69) dengan rerata lama observasi 15,4 bulan. Terdapat pengaruh riwayat merokok (p=0,000) dan faktor usia (p=0,000) terhadap terjadinya komplikasi pasca pemasangan plat dengan hazard ratio riwayat merokok 9,19 dan faktor usia 10-20 tahun dibanding diatas 60 tahun sebesar 153,8. Angka survival plat pada pasien tidak merokok berada diatas 80% pada 2 tahun pertama, tahun ketiga 60% dan setelah itu dapat menurun hingga 20-40%.
Kesimpulan: Merokok dan faktor usia berpengaruh terhadap kejadian komplikasi pasca rekonstruksi mandibula. Jika memungkinkan, rekonstruksi mandibula hanya dengan plat rekonstruksi merupakan tindakan sementara, perlu dipertimbangkan penggunaan graft baik vascularized maupun non-vascularized.

Background: Treatment of reconstruction in post-mandibular resection patients using only plate reconstruction is commonly performed in several hospitals in Indonesia. Some complications that can occur after reconstruction of the mandible can be expose plates, plate fractures and fistulas.
Aim: The purpose of this study will look for several factors that influence the occurrence of these complications.
Material and method: A retrospective study from 2012-2017 taken from medical records. Data on benign mandibular tumors (location, size, length), patient systemic data (smoking history, diabetes, nutritional status) and operating data (duration, reconstruction plate system) were associated with the incidence of complications, analyzed using Kaplan Meier Survival Curve and Cox Proportional Regression Hazard.
Result: Sixty-nine data with the prevalence of complications 21.73% (15/69) with an average observation time 15.4 months. There was an effect of smoking history (p = 0,000) and age factor (p = 0,000) on the occurrence of postoperative complications with hazard ratio of smoking history 9,19 and age factor 10-20 years compared to over 60 years is 153,8. The plate survival rate in patients who do not smoke is above 80% in the first 2 years, the third year is 60% and after that it can decrease by 20-40%.
Conclusion: Smoking and age factors influence the incidence of post-reconstruction mandibular complications. If possible, mandible reconstruction using a reconstruction plate is temporary procedure, it is necessary to consider the use of either vascularized or non-vascularized grafts.
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Jakarta: Fakultas Kedokteran Gigi Universitas Indonesia, 2018
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UI - Skripsi Membership  Universitas Indonesia Library
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Surya Nelis
"Latar belakang: Thalassemia merupakan kelainan genetik yang paling banyak ditemukan di seluruh dunia. Penyakit ini dapat menimbulkan berbagai masalah dan kelainan berbagai organ tubuh, termasuk pada rongga mulut.
Tujuan: memperoleh gambaran mengenai kelainan yang terjadi pada rongga mulut pasien thalassemia mayor di Pusat Thalassemia RSCM.
Metode: Penelitian cross-sectional terhadap 76 pasien thalassemia mayor yang berusia diatas 12 tahun. Data didapat dengan melakukan pemeriksaan klinis dan wawancara terstruktur menggunakan panduan kuesioner.
Hasil: Keluhan subyektif dalam rongga mulut yang sering dialami adalah: serostomia, diikuti dengan sariawan berulang, bibir mengelupas dan pecah-pecah, serta gusi berdarah. Prevalensi kelainan klinis yang ditemukan meliputi: inkompetensi bibir (25,0%); malokusi: klas I (40,79%), klas II (51,32%) dan klas III (3,95%); higiene oral buruk (67,11%), dan gingivitis (82,89%). Nilai rata-rata DMF-T adalah 4,97. Kondisi dan lesi patologik mukosa mulut yang paling banyak ditemukan adalah pigmentasi mukosa (69,74%), diikuti dengan depapilasi lidah (56,58%), mukosa ikterik (52,63%), cheilosis/cheilitis (50,0%), mukosa pucat (44,74%), erosi/deskuamasi mukosa (44,74%), stomatitis aftosa rekuren (15,79%), glositis defisiensi (14,47%) dan perdarahan gingiva (11,84%).
Kesimpulan: Maloklusi, higiene oral buruk, gingivitis, serostomia, pigmentasi mukosa, depapilasi lidah, mukosa ikterik, dan cheilosis/cheilitis, merupakan masalah yang paling umum ditemukan pada pasien thalassemia mayor dalam penelitian ini, namun indeks karies gigi terlihat rendah.

Background: Thalassemia is the most common genetic disorders worldwide. The disease can cause various problems and disorders of various organs of the body, including in the oral cavity.
Objective: to describe the oral cavity disorders in patients with major thalassemia in Thalassemia Centre at Cipto Mangunkusumo Hospital.
Methods: cross-sectional study involved 76 patients with major thalassemia over 12 years of age. Data obtained by clinical examination and structured interviews using guidance from quistionnare.
Results: Oral subjective symptom which is often experienced is xerostomia, followed by recurrent aphthous stomatitis, cheilosis/cheilitis, and gingival bleeding. Prevalence of clinical findings consist of: incompetence of lips (25%); malocclusion: class I (40,79%), class II (51,32%) and class III (3,94%); poor oral hygiene (67,11), gingivitis (82,89%). DMF-T score was 4,97. Conditions and pathologic lesions more frequently seen are pigmentation of mucosa (69,74%), followed by depapillation of tongue (56,58%), icterus of mucosa (52,63%), cheilosis/cheilitis (50%), pallor of mucosa (44,74%), erosion/desquamation of mucosa (44,74%), recurrent aphthous stomatitis (15,79%), glossitis deficiency (14,47%), and gingival bleeding (11,84%).
Conclusion: Malocclusion, poor oral hygiene, gingivitis, xerostomia, pigmentation of mucosa, depapillation of tongue, icterus of mucosa, and cheilosis/cheilitis, were most prevalent problems in patients with major thalassemia in this study; nevertheless, dental caries show low index.
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Jakarta: Fakultas Kedokteran Gigi Universitas Indonesia, 2013
T35045
UI - Tesis Membership  Universitas Indonesia Library
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Agnes Yunie Purwita Sari
"ABSTRAK
Latar belakang. Upaya peningkatan pencapaian pemberian ASI pada bayi sakit sangat diperlukan. Penelitian ini bertujuan untuk mengetahui pengaruh Focus
Group Discussion tenaga kesehatan terhadap peningkatan pemberian ASI.
Metode. Penelitian ini merupakan operational research, dengan FGD dan
wawancara mendalam sebagai intervensi. Diagram fishbone digunakan untuk analisis masalah. Tingkat pemberian ASI dibandingkan sebelum FGD dan setelah FGD.
Hasil. Terdapat 257 subjek penelitian, yaitu 177 subjek sebelum FGD dan 80
subjek setelah FGD. Proporsi subjek yang mendapat ASI selama perawatan adalah 97,5% setelah FGD dan 82,9% sebelum FGD (X1
2=9,43 p=0,002). Subjek yang mendapat ASI dalam 0-4 jam lebih tinggi setelah FGD (10(12,5%)) dibandingkan sebelum FGD (6,(3,5%)) (X5
2=52,5; p<0. 001). Kendala program pemberian ASI
diselesaikan dengan 1) dukungan Manajemen Rumah Sakit, 2) dukungan petugas
kesehatan kepada ibu menyusui, 3) dukungan suami dan keluarga kepada ibu
menyusui, 4) biaya, 5) faktor lain seperti level perawatan dan FGD secara secara konsisten, dan 6) diperlukan penelitian kohort prospektif.
Simpulan. FGD petugas kesehatan meningkatkan pemberian ASI selama perawatan, serta mempercepat inisiasi pemberian ASI. Perangkat diagram
fishbone dalam FGD dapat menganalisis kendala pelaksanaan program pemberian
ASI pada bayi sakit.ABSTRACT Background. Improving breastfeeding in sick infants is essential. The purpose of this study is to analyse the influence of Focus Group Discussion (FGD) on
healthcare workers on breastfeeding achievement in sick infants.
Methods. This study was an operational research using FGD and in-depth interviews an intervention. Fishbone diagram was used to analyse problems.
Breastfeeding achievement was compared before FGD and after FGD.
Results. There were 257 subjects, 177 infants before FGD and 80 infants after
FGD. The proportion of subjects with breastfeeding during admission was 97.5%
after the FGD, and 82.9% before the FGD (x1
2 = 9.43; p = 0.002). Breastfeeding
initiation in 0-4 hours was higher after the FGD, 10 (12.5%) compared to 6
(3.5%) before the FGD (x5
2 = 52.5; p < 0.001). The solutions for breastfeeding
problems were: 1) Supporting for the hospital management, 2) supporting of healthcare workers for breastfeed mothers, 3) supporting of husband and family
for breastfeed mother, 4) finance, 5) other factors such as admission level and
FGD consistently. 6) and a prospective cohort study was required.
Conclusions. FGD increased breastfeeding acheivement during admission, and
accelerated breastfeeding initiation. Fishbone diagram effectively analyzed the
problems or difficulties on breastfeeding programs for sick babies;Background. Improving breastfeeding in sick infants is essential. The purpose of this study is to analyse the influence of Focus Group Discussion (FGD) on
healthcare workers on breastfeeding achievement in sick infants.
Methods. This study was an operational research using FGD and in-depth interviews an intervention. Fishbone diagram was used to analyse problems.
Breastfeeding achievement was compared before FGD and after FGD.
Results. There were 257 subjects, 177 infants before FGD and 80 infants after
FGD. The proportion of subjects with breastfeeding during admission was 97.5%
after the FGD, and 82.9% before the FGD (x1
2 = 9.43; p = 0.002). Breastfeeding
initiation in 0-4 hours was higher after the FGD, 10 (12.5%) compared to 6
(3.5%) before the FGD (x5
2 = 52.5; p < 0.001). The solutions for breastfeeding
problems were: 1) Supporting for the hospital management, 2) supporting of healthcare workers for breastfeed mothers, 3) supporting of husband and family
for breastfeed mother, 4) finance, 5) other factors such as admission level and
FGD consistently. 6) and a prospective cohort study was required.
Conclusions. FGD increased breastfeeding acheivement during admission, and
accelerated breastfeeding initiation. Fishbone diagram effectively analyzed the
problems or difficulties on breastfeeding programs for sick babies"
Fakultas Kedokteran Universitas Indonesia, 2016
SP-PDF
UI - Tugas Akhir  Universitas Indonesia Library
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Fyrnaz Kautharifa
"Latar Belakang. Miopati inflamasi idiopatik (MII) merupakan jenis miopati acquired dengan pola kelemahan ekstremitas predominan proksimal dengan prevalensi secara global yaitu 2.4-33.8 per 100.000 per tahun. Di Indonesia, data mengenai prevalensi MII belum diketahui secara pasti namun terdapat studi mengenai profil MII di Rumah Sakit Cipto Mangunkusomo (RSCM) yaitu probable MII sebanyak 33% dan Definite MII sebanyak 67%. Keterlibatan organ ekstraskeletal dan berbagai macam faktor lain dapat berdampak pada aspek fisik, mental dan sosial yang dapat mempengaruhi kualitas hidup pasien MII. Penelitian ini bertujuan untuk mengetahui kualitas hidup pasien MII dan faktor-faktor yang mempengaruhinya. Metode. Penelitian ini menggunakan desain potong lintang yang dilakukan pada Januari hingga Mei 2024 di RSUPN Cipto Mangunkusumo Jakarta. Faktor demografis, fenotipe klinis, subtipe, pemeriksaan penunjang kegansan dan pelaku rawat dinilai hubungannya dengan kualitas hidup pasien MII. Penilaian kualitas hidup\dinilai dengan ShortForm Health Survey-36 (SF-36) versi Indonesia yang mengukur delapan domain kualitas hidup: fungsi fisik, peran fisik, nyeri tubuh, kesehatan umum, vitalitas, fungsi sosial, peran emosional, dan kesehatan mental. Hasil. Total subjek pada penelitian ini adalah 58 orang dan didominasi oleh prempuan sebanyak 69% dengan rerata usia adalah 39.09 ± 13.08 tahun. Rerata skor total SF-36 yaitu 51.07 ± 21.67, domain PCS didapatkan rerata 42.13 ± 21.68 dan domain MCS dengan median 56.00 (2-100). Faktor-faktor yang secara signifikan berhubungan dengan kualitas hidup pasien MII baik pada skor total meliputi nyeri, fatigue, keterbatasan fisik, kemampuan berpindah tempat, keterlibatan sendi, ansietas, depresi dan pelaku rawat sementara pada subtipe MII berupa PM memiliki skor kualitas hidup terendah bila dibandingkan dengan subtipe lainnya. Kesimpulan. Berdasarkan skor SF-36 maka kualitas hidup pasien MII lebih rendah bila dibandingkan dengan populasi normal. Beberapa faktor telah diketahui memiliki hubungan yang signifikan terhadap kualitas hidup pasien. Tatalaksana secara komprehensif dan holistik melibatkan multidisiplin sehingga dapat meningkatkan kualitas hidup pasien MII

Background. Idiopathic inflammatory myopathy (MII) is a type of acquired myopathy with proximal predominant limb weakness and a global prevalence of 2.4-33.8 per 100,000 per year. In Indonesia, data on the prevalence of MII is not yet known with certainty, however, a recent study on the profile of MII at Cipto Mangunkusomo Hospital (RSCM) identified 33% of patients with probable MII and 67% of patients with definite MII.. Extraskeletal organ involvement and various other factors can have an impact on physical, mental and social aspects that can affect the quality of life of MII patients. This study aims to determine the quality of life of MII patients and the factors that influence it. Methods. This study used a cross-sectional design conducted from January to May 2024 at Cipto Mangunkusumo Hospital Jakarta. Demographic factors, clinical phenotypes, subtypes, supporting examinations and caregivers were assessed for their association with the quality of life of MII patients. Quality of life assessment was performed according to the recommendations of the International Myositis Assessment and Clinical Studies Group (IMACS), namely the Short-Form Health Survey-36 (SF-36) questionnaire which measures eight quality of life domains: physical function, physical role, body pain, general health, vitality, social function, emotional role, and mental health. Results. The total subjects in this study were 58 people and were dominated by women as much as 69% with an average age of 39.09 ± 13.08 years. Cutaneous manifestaons was the most common organ involvement 72.4% The mean total score of SF- 36 is 51.07 ± 21.67, the PCS domain obtained a mean of 42.13 ± 21.68 and the MCS domain with a median of 56.00 (2-100). Factors associated with the quality of life of MII patients in the total score include pain, fatigue, physical limitations, ability to move, joint involvement, anxiety, depression and perpetrators of care while the MII PM subtype has the lowest quality of life score when compared to other subtypes. Conclusion. Based on SF-36 scores, the quality of life of MII patients is lower in comparisonto the normal population. Several factors have been known to have a significant relationship with the quality of life of patients. Comprehensive and holistic management involving multidisciplinary can improve the quality of life of MII patients."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2024
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UI - Tugas Akhir  Universitas Indonesia Library
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Grace Boaz
"[Pendahuluan:
Fraktur yang mengenai midface akan menyebabkan gangguan fungsi baik fungsi mata maupun oklusi. Walaupun angka kejadian fraktur midface cukup tinggi, terdapat gangguan fungsional, dan membutuhkan biaya yang besar untuk tatalaksana menggunakan mini plate dan screw, tidak ada informasi mengenai hasil fungsional setelah tatalaksana fraktur midface.
Metode:
Data mengenai status fungsional pasien dengan fraktur midface sebelum operasi ORIF didapatkan dari data rekam medis dan data setelah operasi ORIF didapatkan dari pemeriksaan objektif dan subjektif. Status fungsional meliputi diplopia, gerakan bola mata, maloklusi, dan gangguan nervus fasialis dan nervus infraorbita.
Hasil:
Semua pasien yang dievaluasi menunjukkan perbaikan status fungsional setelah operasi ORIF.
Kesimpulan:
Pasien dengan fraktur midface yang telah menjalani operasi ORIF di Divisi Bedah Plastik Rumah Sakit Cipto Mangunkusumo menunjukkan adanya perbaikan pada diplopia, gerakan bola mata, oklusi, dan fungsi nervus fasialis dan infraorbita pada evaluasi jangka panjang.;Background:
Fractures involving the midface present more challenges due to the impairment on function both occlusion and visual function. In spite of the high number of occurrence, high impact to the impairment on function, and high cost in the treatment due to relatively expensive hardware required (mini plate and screw), there is inadequate information about the outcome after treating midface fracture.
Methods:
Data on functional status of patients with midface fracture before ORIF surgery collected from medical records and data after ORIF surgery gathered objectively and subjectively. Functional status including diplopia, eye motility, cranial facial nerve impairment, infraorbita nerve impairment and malocclusion.
Results:
All of the patients that have been evaluated was showing improvement in total functional status after treatment with ORIF surgery.
Conclusion:
Midface fracture patients underwent ORIF surgery in Plastic Surgery Division, Cipto Mangunkusumo hospital, resulted in the recovery of eye motility function, diplopia, malocclusion and facial and infraorbital nerve impairment at longterm evaluation., Background:
Fractures involving the midface present more challenges due to the impairment on function both occlusion and visual function. In spite of the high number of occurrence, high impact to the impairment on function, and high cost in the treatment due to relatively expensive hardware required (mini plate and screw), there is inadequate information about the outcome after treating midface fracture.
Methods:
Data on functional status of patients with midface fracture before ORIF surgery collected from medical records and data after ORIF surgery gathered objectively and subjectively. Functional status including diplopia, eye motility, cranial facial nerve impairment, infraorbita nerve impairment and malocclusion.
Results:
All of the patients that have been evaluated was showing improvement in total functional status after treatment with ORIF surgery.
Conclusion:
Midface fracture patients underwent ORIF surgery in Plastic Surgery Division, Cipto Mangunkusumo hospital, resulted in the recovery of eye motility function, diplopia, malocclusion and facial and infraorbital nerve impairment at longterm evaluation.]"
Fakultas Kedokteran Universitas Indonesia, 2014
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UI - Tugas Akhir  Universitas Indonesia Library
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Muhammad Ramaditto
"Latar belakang: Kehilangan darah memiliki pengaruh terhadap kejadian komplikasi pasca operasi. Kehilangan darah intraoperatif berfungsi sebagai penanda keberhasilan operasi dan prognosis bagi pasien. Prosedur bedah seperti bedah ortognatik termasuk bedah mayor dengan resiko kehilangan darah intraoperatif yang banyak. Kehilangan darah setelah bedah ortognatik sangat bervariasi, dan terkadang diperlukan transfusi. Ahli bedah perlu mengevaluasi faktor yang mempengaruhi kehilangan darah intraoperatif dan menilai tingkat transfusi sehingga dapat mengurangi resiko komplikasi kehilangan darah dan menghindari penggunaan transfusi berlebihan.
Tujuan: Studi ini bertujuan untuk menganalisis hubungan lama operasi, jenis bedah ortognatik dan indeks massa tubuh terhadap jumlah kehilangan darah intraoperatif pada bedah ortognatik.
Metode: Studi ini menggunakan metode analitik observasional dengan desain penelitian retrospektif.
Hasil: Terdapat hubungan yang signifikan antara jenis bedah ortognatik dan lama operasi dengan kehilangan darah intraoperatif pada pasien bedah ortognatik. Double jaw surgery dan Lefort I osteotomy serta faktor lama operasi menunjukkan adanya korelasi yang kuat terhadap jumlah kehilangan darah intraoperatif pada pasien bedah ortognatik. Indeks massa tubuh tidak menunjukkan hubungan yang signifikan terhadap jumlah kehilangan darah intraoperatif pada pasien bedah ortognatik.
Kesimpulan: Jenis bedah ortognatik double jaw surgery dan Lefort I osteotomy serta lama operasi lebih dari 5 jam mempengaruhi jumlah kehilangan darah intraoperatif yang signifikan pada pasien bedah ortognatik.

Background: Blood loss has an influence on the incidence of postoperative complications. Intraoperative blood loss can be serves as a marker of successful surgery and prognosis for patients. Surgical procedures such as orthognathic surgery is one of major surgery with a high risk of intraoperative blood loss. Blood loss after orthognathic surgery varies greatly, and sometimes transfusion is needed. Surgeons need to evaluate factors that affect intraoperative blood loss and assess transfusion rates so as to reduce the risk of blood loss complications and avoid excessive transfusion use.
Objective: This study aims to analyze the relationship between duration of surgery, type of orthognathic surgery and body mass index to the amount of intraoperative blood loss in orthognathic surgery.
Method: This study uses observational analytic methods with a retrospective research design.
Results: There is a significant relationship between the type of orthognathic surgery and the length of surgery with intraoperative blood loss in orthognathic surgery patients. Double jaw surgery and Lefort I osteotomy as well as the duration of surgery showed a strong correlation with the amount of intraoperative blood loss in orthognathic surgery patients. Body mass index did not show a significant relationship to the amount of intraoperative blood loss in orthognathic surgical patients.
Conclusion: The type of orthognathic double jaw surgery and Lefort I osteotomy as well as the operating duration of more than 5 hours affect the amount of significant intraoperative blood loss in orthognathic surgery patients.
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Depok: Fakultas Kedokteran Gigi Universitas Indonesia, 2020
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UI - Tesis Membership  Universitas Indonesia Library
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Rebecca Darryl Cynthia
"Kanker kolorektal merupakan kanker di kolon dan rektum dan termasuk kanker terbanyak keempat di Indonesia dengan insidensi sekitar 34.000 kasus setiap tahunnya. Salah satu faktor risiko kanker kolorektal adalah merokok yang mengandung banyak zat karsinogen, salah satunya nikotin. Nikotin bisa meningkatkan proliferasi sel, memicu mutasi DNA, inflamasi sistemik, dan menyebabkan stres oksidatif pada jaringan kolorektal, tetapi penelitian mengenai gambaran kebiasaan merokok pada pasien kanker kolorektal di Indonesia masih sangat terbatas. Penelitian ini bertujuan untuk mengetahui gambaran kebiasaan merokok pasien kanker kolorektal usia 40-70 tahun di Indonesia secara spesifik di RS Cipto Mangunkusumo. Desain penelitian ini adalah potong lintang deskriptif dan penelitian dilakukan dengan membagikan kuesioner yang diadaptasi dari “Kuesioner Individu Riskesdas 2018” melalui Google Form kepada pasien kanker kolorektal usia 40-70 tahun yang terdata di rekam medis Rumah Sakit Cipto Mangunkusumo lalu hasil kuesioner tersebut dianalisis lebih lanjut. Terdapat 51 subjek penelitian yang menjawab pertanyaan kuesioner hingga selesai dan lengkap. Terdapat 17 dari 51 pasien (33,3%) yang memiliki riwayat merokok sebelumnya, 5 dari 12 pasien (41,7%) yang menghisap rokok kurang dari 10 batang per hari, 11 dari 17 pasien (64,7%) yang durasi merokoknya lebih dari 30 tahun, dan jenis rokok yang paling banyak dihisap adalah rokok kretek (41,2%).

Colorectal cancer is cancer in the colon and rectum and the fourth most common cancer in Indonesia with an incidence of around 34.000 cases each year. One of the risk factors for colorectal cancer is smoking that contains many carcinogenic, for example nicotine. Nicotine can increase cell proliferation, trigger DNA mutations, systemic inflammation, and cause oxidative stress in colorectal tissue but research regarding the description of smoking habits in colorectal cancer patients in Indonesia is still very limited. This study aims to determine the smoking habits of colorectal cancer patients aged 40-70 years in Indonesia specifically at Cipto Mangunkusumo Hospital. The design of this research was cross sectional descriptive and was carried out by distributing questionnaires adapted from the “Kuesioner Individu Riskesdas 2018” via Google Form to colorectal cancer patients aged 40-70 years who were recorded in the Cipto Mangunkusumo Hospital medical records. There were 51 research subjects who answered the questionnaire questions completely. There were 17 of 51 patients (33,3%) who had a previous history of smoking, 5 of 12 patients (41,7%) who smoke less than 10 cigarrette per day, 11 of 17 patients (64,7%) whose duration of smoking was more than 30 years, and the type of cigarette that is most often smoked is kretek cigarettes (41,2%)."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2023
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UI - Skripsi Membership  Universitas Indonesia Library
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