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Ditemukan 26716 dokumen yang sesuai dengan query
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Septiana Andri Wardana
Kualitas Hidup Pasien Meningitis Tuberkulosis Selesai Obat Anti-tuberkulosis = Quality of Life Among Tuberculous Meningitis Patients Upon Completion of Anti-tuberculosis Treatment
"Latar Belakang. Prevalensi disabilitas pada pasien meningitis tuberkulosis (MTB) hampir setara dengan angka mortalitas mencapai 29-50%. Aspek luaran pasien MTB tidak cukup dinilai berdasarkan angka morbiditas dan mortalitasnya, namun mencakup kesehatan fisik, mental, dan sosial seperti yang didefinisikan oleh World Health Organization (WHO). Penelitian ini bertujuan untuk mengetahui kualitas hidup pasien MTB selesai obat anti-tuberkulosis (OAT) dan faktor-faktor yang memengaruhinya. Metode. Studi potong lintang (cross sectional) dilakukan pada pasien MTB, termasuk tuberkuloma selesai OAT di RSUPN dr. Cipto Mangunkusumo periode Mei 2019-Juni 2023. Karakteristik demografis, klinis, diagnosis, tatalaksana pasien dinilai dari data rekam medis dan wawancara. Luaran kualitas hidup pasien dinilai menggunakan kuesioner SF (Short form)-36. Analisis statistik dilakukan dengan SPSS versi 19.0, yaitu Mann-Whitney dan Kruskal-Wallis untuk data kategorik, Spearman untuk data numerik. Hasil. Dari 53 subjek penelitian dengan median usia 30 (IQR 25,5-39) tahun, didapatkan median skor SF-36 yaitu, 86,5 (IQR 74,9-92,8). Median (IQR) skor pada aspek fisik (PCS) dan mental (MCS) kualitas hidup serupa, yaitu 85 (IQR 69,4-94,85) dan 88,1 (IQR 74,1-95,3). Faktor yang berhubungan dengan kualitas hidup pasien MTB selesai OAT antara lain penghasilan (p=0,033), kejang (p=0,028), kelemahan motorik (p=0,023), dan mRS saat pulang perawatan (p=0,007). Faktor yang berhubungan dengan skor PCS adalah pekerjaan (p=0,012), penghasilan (p=0,007), kelemahan motorik (p=0,024), dan mRS saat pulang perawatan (p=0,01). Faktor yang berhubungan dengan skor MCS adalah usia (p=0,006) dan kejang (p=0,025). Kesimpulan. Kualitas hidup pasien MTB selesai OAT berdasarkan skor SF-36, PCS, dan MCS tergolong baik. Faktor yang memengaruhi kualitas hidup lebih tinggi pada pasien MTB selesai OAT adalah berpenghasilan, tanpa klinis kejang atau kelemahan motorik, dan mRS saat pulang perawatan 0-2. Faktor yang memengaruhi aspek fisik lebih tinggi adalah pekerjaan, berpenghasilan, tanpa klinis kelemahan motorik, dan mRS saat pulang perawatan 0-2, sedangkan aspek mental lebih tinggi adalah usia ≥30 tahun dan tanpa klinis kejang. Kata kunci. Kualitas hidup, meningitis tuberkulosis, selesai OAT, SF-36<
The prevalence of disabilities among tuberculous meningitis (TBM) patients almost similar with its mortality rate (29-50%). The comprehensive evaluation of long-term outcomes should encompass not only morbidity and mortality rates but also incorporate the dimensions of physical, mental, and social well-being as outlined by the World Health Organization (WHO). This study aimed to assess the quality of life (QoL) among patients with TBM following the completion of anti-tuberculosis treatment (ATT) and investigating the factors that have impacts on this particular aspect. Methods. Retrospective cross sectional study of TBM patients, including tuberculoma upon completion of ATT at dr. Cipto Mangunkusumo National Center General Hospital during May 2019-June 2023. Demographic, clinical, diagnostic, and treatment characteristics were conducted by medical records and interviews. The assessment of QoL in TBM patients was performed using Short form (SF)-36 questionnaire. Statistical analysis was performed with SPSS version 19.0 (Mann-Whitney and Kruskal-Wallis for categorical data, Spearman for numeric data). Result. The study involved 53 participants, with median of age 30 (IQR 25.5-39) years, demonstrated favorable median SF-36 score of 86.5 (IQR 74.9-92.8). Median of physical score (PCS) and mental score (MCS) almost similar, 85 (IQR 69.4-94.85) and 88.1 (IQR 74.1-95.3), respectively. The impact of various factors on QoL was assessed, revealing significant associations with monthly income (p=0.033), presence of seizure (p=0.028), motoric abnormalities (p=0.023), and mRS at discharge (p=0.007). Employment (p=0.012), monthly income (p=0.007), motoric abnormalities (p=0.024), and mRS at discharge (p=0.01) were identified as factors influencing the PCS score. Age (p=0.006) and presence of seizure (p=0.025) found to impact the MCS score. Conclusion. The evaluation of QoL in TBM patients after completing ATT utilizing SF-36 score, PCS, and MCS revealed favorable outcome. Several factors were found to significantly influence higher SF-36 score, including monthly income, absence of seizure and motoric abnormalities, and mRS at discharge of 0-2. Similarly, factors such as employment, monthly income, absence motoric abnormality, and mRS at discharge of 0-2 were associated with higher PCS scores. Furthermore, a higher MCS score was observed in patients aged 30 years or older and those without seizures. Keywords. Quality of life, QoL, tuberculous meningitis, completion ATT, SF-36"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2023
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Anja Hesnia Kholis
Pengalaman pasien post meningitis dan ensefalitis tentang kualitas hidupnya = The experience of post meningitis and encephalitis patients about their quality of life / Anja Hesnia Kholis
"[ABSTRAK
Meningitis dan ensefalitis merupakan infeksi sistem saraf pusat yang dapat
mengancam jiwa. Apabila tidak ditangani dengan baik, akan menimbulkan defisit
neurologis dan berdampak pada kehidupan sehari-hari. Tujuan penelitian ini
adalah mengeksplorasi secara mendalam pengalaman hidup pasien postmeningitis
dan ensefalitis terkait kualitas hidupnya. Penelitian kualitatif dengan
pendekatan fenomenologi pada delapan partisipan ini ditentukan dengan teknik
snowball sampling. Data dikumpulkan dengan wawancara mendalam dan catatan
lapangan. Analisis data menggunakan metode Collaizi. Tema yang ditemukan
adalah perubahan fungsi tubuh pasien, masalah sosial yang dihadapi pasien postmeningitis
dan ensefalitis, strategi koping pasien, kebutuhan akan support system
pasien, dan pengalaman pasien selama menerima pelayanan kesehatan. Hasil
penelitian diharapkan sebagai data dasar pengembangan format pengkajian asuhan
keperawatan dan instrumen kualitas hidup neuroinfection.
ABSTRACT
Meningitis and encephalitis are life-threatening infection of the central nervous
system. If it is not treated properly, will lead to neurological deficits and impact
on daily life. The purpose of this study was to explore the life experiences of postmeningitis
and encephalitis patients related to their quality of life. Qualitative
research with phenomenological approach on eight participants involved were
determined by snowball sampling technique. The data was collected by in-depth
interviews and field notes. Collaizi?s method was used to data analysis. The
results of this investigation were: the changes body function of patients; the social
problems faced by post-meningitis and encephalitis patients; the coping strategies
of patients; the need support system of patients, and the experience patients during
receiving health care. The study findings are expected to be the basic for both the
development of nursing care assessment form and instrument of neuroinfection
related to quality of life., Meningitis and encephalitis are life-threatening infection of the central nervous
system. If it is not treated properly, will lead to neurological deficits and impact
on daily life. The purpose of this study was to explore the life experiences of postmeningitis
and encephalitis patients related to their quality of life. Qualitative
research with phenomenological approach on eight participants involved were
determined by snowball sampling technique. The data was collected by in-depth
interviews and field notes. Collaizi’s method was used to data analysis. The
results of this investigation were: the changes body function of patients; the social
problems faced by post-meningitis and encephalitis patients; the coping strategies
of patients; the need support system of patients, and the experience patients during
receiving health care. The study findings are expected to be the basic for both the
development of nursing care assessment form and instrument of neuroinfection
related to quality of life.]"
2015
T44547
UI - Tesis Membership  Universitas Indonesia Library
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Raesa Yolanda
Alur Perjalanan Pasien Meningitis Tuberkulosis Sebelum Mendapatkan Pengobatan di Rumah Sakit Rujukan Tersier RSUPN Dr. Cipto Mangunkusumo Jakarta = Tuberculous Meningitis Patient Pathway Before Getting Treatment at Tertiary Referral Hospital RSUPN Dr. Cipto Mangunkusumo Jakarta
"Latar Belakang: Meningitis tuberkulosis (TBM) merupakan manifestasi terberat infeksi TB dan prognosisnya bergantung pada kecepatan memulai terapi. Studi ini bertujuan mengetahui alur perjalanan pasien TBM serta faktor-faktor yang memengaruhi keterlambatan dalam mendapatkan pengobatan.
Metode Penelitian: Penelitian ini merupakan studi potong lintang dari pasien TBM yang sudah mendapatkan terapi OAT dan dirawat di RSCM pada bulan Januari 2020 – April 2022. Data diperoleh melalui wawancara terhadap pasien atau pendamping dan telusur rekam medis.
Hasil: Sebanyak 99 orang subjek yang memenuhi kriteria. Terdapat 6 pola alur perjalanan pasien dengan yang terbanyak adalah mengalami gejala umum diikuti gejala neurologis, mencari pertolongan kesehatan, terdiagnosis, dan mendapatkan pengobatan (52,5%). Fasilitas kesehatan pertama terbanyak dikunjungi pasien adalah praktek dokter swasta (L1b) (35,4%). Median jumlah kunjungan yang dibutuhkan pasien untuk mendapatkan pengobatan adalah 6 (4-9) kunjungan dengan durasi keterlambatan sebagai berikut: keterlambatan pasien 17 (3-33) hari, keterlambatan diagnosis 44 (16-101) hari, keterlambatan pengobatan 1 (0-1) hari, dan keterlambatan total adalah 78 (33-170) hari. Faktor yang secara signifikan berhubungan dengan keterlambatan yang lebih panjang (>78 hari) adalah jumlah kunjungan ke fasilitas kesehatan aOR=3,51 (CI95=1,36-9,10; p=0,01) dan pendidikan rendah aOR=0,30 (CI95=0,01-0,89; p=0,03).
Kesimpulan: Pasien TBM di RSCM menjalani kunjungan multipel dan membutuhkan waktu 2,5 bulan sejak mengalami gejala hingga mendapatkan pengobatan dengan keterlambatan terbesar berasal dari sistem kesehatan.
Background: Tuberculous meningitis (TBM) is the worst manifestation of TB infection. Its prognosis is depend on timely treatment initiation. This study intend to know TBM patient pathway and factors that affect treatment delay.
Methods: This was a crossectional study of TBM patients who have received antituberculous medication and were admitted at the RSCM January 2020-April 2022. Data were obtained from interview to either patient or caregiver and medical reccord.
Results: A total of 99 subjects met the criteria. There were 6 patterns of patient pathway with the most prevalent is having general symptoms followed by neurological symptoms, first healthcare visit, diagnosed, and treated (52.5%). The first healthcare visited by most patients was private doctor's practice (L1b) (35.4%). Median number of visits before recieving treatment was 6 (4-9) visits. Delay duration are as follow: patient delay 17 (3-33) days, diagnosis delay 44 (16-101) days, treatment delay 1 (0-1) day, and total delay 78 (33-170) days. Factors that significantly associated with longer delays were number of visits to healthcare facilities aOR=3.51 (CI95=1.36-9.10; p=0.01) and lower education aOR=0.30 (CI95=0 .01-0.89; p=0.03).
Conclusions: TBM patients experienced multiple visit and had 2.5 months delay from first symptoms to treatment with the longest delay coming from the healthcare system."
Depok: Fakultas Kedokteran Universitas Indonesia, 2022
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UI - Tesis Membership  Universitas Indonesia Library
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Siti Dzatir Rohmah
Evaluasi Kualitatif Penggunaan Antibiotik pada Pasien Meningitis Bakterial di RSUP Fatmawati dengan Metode Gyssens Periode Januari 2014-November 2022 = Qualitative Evaluation of Antibiotic Use in Bacterial Meningitis Patients at Fatmawati General Hospital Using The Gyssens Method During The Period January 2014 to November 2022
"Meningitis bakterial dianggap sebagai kasus kegawatdaruratan neurologik dengan angka morbiditas dan mortalitas yang tinggi. Mortalitas akibat meningitis bakterial dapat mencapai 34% terutama pada infeksi yang disebabkan oleh S. pneumoniae dan L. meningitidis. Sementara morbiditas pada pasien meningitis bakterial yaitu sekuele neurologis jangka panjang dapat mencapai 50% pada survivor meningitis. Terapi antibiotik dengan penggunaan yang rasional dapat menurunkan angka kematian. Sebaliknya, penggunaan terapi antibiotik yang tidak rasional akan meningkatkan terjadinya resistensi yang berdampak pada peningkatan morbiditas, mortalitas, dan biaya kesehatan. Penelitian ini bertujuan untuk mengetahui kualitas penggunaan antibiotik pada pasien meningitis bakteri dengan metode Gyssens. Penelitian ini merupakan penelitian observasional dengan metode retrospektif cross-sectional yang dilakukan di Rumah Sakit Umum Fatmawati, Jakarta. Subyek penelitian adalah 27 pasien meningitis bakterial yang memenuhi kriteria inklusi. Berdasarkan evaluasi penggunaan antibiotik diagram alir Gyssen diperoleh hasil 11 (40,7%) subyek menggunakan antibiotik yang tepat dan 16 subyek (59,3%) menggunakan antibiotik yang tidak tepat. Penggunaan antibiotik yang belum tepat tersebar dalam beberapa kategori sebagai berikut yaitu kategori IVc sejumlah 2 subyek (7,4%), kategori IVd sejumlah 2 subyek (7,4%), kategori IIIA sejumlah 3 subyek (11,1%), kategori IIIB sejumlah 1 subyek (3,7%), kategori IIA sebanyak 13 subyek (48,1%), dan kategori IIB sebanyak 3 subyek (11,1%). Penggunaan antibiotik yang sesuai berdasarkan evaluasi menggunakan algoritma Gyssen pada penelitian ini tidak memberikan pengaruh yang bermakna terhadap outcome pasien dengan nilai p=1,000 (nilai p>0.05). Variabel jenis kelamin merupakan variabel yang berpengaruh secara signifikan (p<00,5) terhadap kerasionalan antibiotik pada pasien meningitis bakterial.
Bacterial meningitis is considered as neurologic emergency with high morbidity and mortality rates. Mortality can reach 34%, especially in infections caused by S. pneumoniae and L. meningitides, while morbidity in bacterial meningitis patients, namely long-term neurologic sequelae, can reach 50% amongst survivors. If antibiotics are used properly, they can lower mortality rates. On the other hand, the irrational use of antibiotic therapy will raise the likelihood of resistance, which raises morbidity, mortality, and costs for health care. This study aims to determine the quality of antibiotic use in bacterial meningitis patients using the Gyssens method. It is an observational study employing the retrospective crosssectional method conducted at Fatmawati General Hospital, Jakarta. The research subjects were 27 patients with bacterial meningitis who met the inclusion criteria. In this study, 40.7% of the subjects had been administered appropriate antibiotics and 59.3% inappropriate ones, which were spread across several categories, namely category IVc for two subjects (7.4%); category IVd for two subjects (7.4%); category IIIA for three subjects (11.1%); category IIIB for one subject (3.7%); category IIA for 13 subjects (48.1%); and category IIB for three subjects (11.1%). The use of appropriate antibiotics based on evaluation using the Gyssens algorithm did not significantly affect patient outcomes (p=1,000). Gender is a variable that has a significant effect (p<00.5) on the rationale for antibiotics in patients with bacterial meningitis."
Depok: Fakultas Farmasi Universitas Indonesia, 2023
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UI - Tesis Membership  Universitas Indonesia Library
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Herbowo Agung F. Soetomenggolo
Long qt syndrome pada pasien dengan keluhan kejang = Long qt syndrome in patients with symptom of seizure
"[ABSTRAK
Latar belakang Long QT syndrome LQTS adalah gangguan irama jantung bergejala kejang yang harus dikenali sejak dini karena dapat menyebabkan kematian mendadak Tujuan Mengetahui angka kejadian LQTS pada pasien dengan keluhan kejang serta karakteristiknya Metode Studi potong lintang terhadap anak yang pernah mengalami kejang tanpa provokasi di poliklinik neurologi anak RSUPN Cipto Mangunkusumo Subyek berusia 6 bulan hingga 17 tahun Panjang QT interval diukur menggunakan EKG dan dinilai menggunakan metode Bazzet Hasil Seratus empat puluh enam pasien kejang mengikuti penelitian ini Usia subyek jenis kelamin serta jenis kejang memiliki sebaran cukup merata Pada penelitian ini didapatkan kelainan penyerta kejang seperti tuli sensorineural autisme keterlambatan perkembangan menyeluruh disabilitas intelektual dan sindroma Rett Sebanyak 20 6 mengalami epilepsi intraktabel Tidak ditemukan subyek dengan pencetus kejang aktivitas fisik dan stres emosional dan hanya 2 7 memiliki riwayat keluarga meninggal mendadak Hasil penilaian QTc pada seluruh subyek di bawah 0 44 detik Nilai QTc terpendek adalah 0 333 detik dan nilai QTc terpanjang adalah 0 437 Nilai tersebut masih dalam rentang normal QTc pada anak Simpulan Pada penelitian ini tidak didapatkan pemanjangan QTc baik pada penderita kejang umum maupun fokal ABSTRACT Background Long QT syndrome LQTS is a heart rhythm disorder with symptom of seizures that should be identified early because it can cause sudden death Aim Knowing the prevalence of LQTS in patients with symptom of seizures and characteristics Method A cross sectional study of children who have experienced an unprovoked seizure in child neurology clinic Cipto Mangunkusumo Subjects aged 6 months to 17 years QT interval was measured by ECG and assessed with Bazzet rsquo s formula Results One hundred and forty six patients with seizures were followed in this study The age sex and seizure rsquo s type of subject distributed evenly In this study we found some disorder along with seizure such as sensorineural deafness autism global developmental delay intellectual disability and Rett syndrome A total of 20 6 had intractable epilepsy We didn rsquo t find subject with physical activity and emotional stress as the trigger of seizure and only 2 7 had a family history of sudden death QTc assessment results in all subjects were under 0 44 seconds The shortest QTc values was 0 333 seconds and the longest QTc value was 0 437 seconds This value is still within the normal range QTc in children Conclusion In this study we concluded that we found no QTc prolongation in patients with seizures ; Background Long QT syndrome LQTS is a heart rhythm disorder with symptom of seizures that should be identified early because it can cause sudden death Aim Knowing the prevalence of LQTS in patients with symptom of seizures and characteristics Method A cross sectional study of children who have experienced an unprovoked seizure in child neurology clinic Cipto Mangunkusumo Subjects aged 6 months to 17 years QT interval was measured by ECG and assessed with Bazzet rsquo s formula Results One hundred and forty six patients with seizures were followed in this study The age sex and seizure rsquo s type of subject distributed evenly In this study we found some disorder along with seizure such as sensorineural deafness autism global developmental delay intellectual disability and Rett syndrome A total of 20 6 had intractable epilepsy We didn rsquo t find subject with physical activity and emotional stress as the trigger of seizure and only 2 7 had a family history of sudden death QTc assessment results in all subjects were under 0 44 seconds The shortest QTc values was 0 333 seconds and the longest QTc value was 0 437 seconds This value is still within the normal range QTc in children Conclusion In this study we concluded that we found no QTc prolongation in patients with seizures , Background Long QT syndrome LQTS is a heart rhythm disorder with symptom of seizures that should be identified early because it can cause sudden death Aim Knowing the prevalence of LQTS in patients with symptom of seizures and characteristics Method A cross sectional study of children who have experienced an unprovoked seizure in child neurology clinic Cipto Mangunkusumo Subjects aged 6 months to 17 years QT interval was measured by ECG and assessed with Bazzet rsquo s formula Results One hundred and forty six patients with seizures were followed in this study The age sex and seizure rsquo s type of subject distributed evenly In this study we found some disorder along with seizure such as sensorineural deafness autism global developmental delay intellectual disability and Rett syndrome A total of 20 6 had intractable epilepsy We didn rsquo t find subject with physical activity and emotional stress as the trigger of seizure and only 2 7 had a family history of sudden death QTc assessment results in all subjects were under 0 44 seconds The shortest QTc values was 0 333 seconds and the longest QTc value was 0 437 seconds This value is still within the normal range QTc in children Conclusion In this study we concluded that we found no QTc prolongation in patients with seizures ]"
Fakultas Kedokteran Universitas Indonesia, 2015
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UI - Tugas Akhir  Universitas Indonesia Library
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Dimas Rahman Setiawan
Komplikasi pemasangan INA-shunt pada pasien anak dengan hidrosefalus dan variasinya = Complications of INA-shunt insertion in pediatric patients with hydrocephalus and its variations
"Latar belakang : Hidrosefalus adalah suatu keadaan terjadinya timbunan cairan serebrospinal (CSS) berlebihan yang disebabkan ketidakseimbangan antara produksi dan absorpsi CSS sehingga mengakibatkan ventrikulomegali dan dapat disertai dengan peningkatan tekanan intrakranial. Salah satu tatalaksana hidrosefalus tersering adalah VP Shunt, yang juga memiliki risiko komplikasi. Indonesia telah dapat membuat sendiri sistem pompa untuk operasi VP Shunt dengan nama INA-shunt. Beberapa penelitian telah meneliti angka komplikasi VP Shunt pada pasien anak, namun belum ada yang meneliti angka komplikasi dengan penggunaan sistem pompa INA-shunt. Tujuan : Mengetahui komplikasi yang terjadi pada pasien anak dengan hidrosefalus dan variasinya yang telah dilakukan operasi VP Shunt dengan pompa INA Shunt beserta faktor yang mempengaruhinya Metode : Penelitian ini bersifat deskriptif retrospektif. Penelitian bersifat multicenter, dengan mengambil data sekunder dari RSUPN Cipto Mangunkusumo, RSAB Harapan Kita, dan RSUP Sardjito. Pada periode Januari 2018-Desember 2019, terdapat 31 subjek yang sesuai dengan kriteria inklusi dan eksklusi. Dilakukan penilaian klinis dan radiologis pascaoperasi dalam kurun waktu 1 tahun untuk mengevaluasi adanya komplikasi pada subjek. Hasil : Dari 31 subjek, terdapat komplikasi pada 5 subjek (16%). Komplikasi itu berupa malfungsi shunt proksimal (10%, n=3), shunt exposed (3%, n=1), dan shunt terinfeksi (3%, n=1). Seluruh komplikasi terjadi pada pasien dengan usia < 3 bulan saat dilakukan VP shunt dan 80% komplikasi terjadi < 6 bulan pascaoperasi. Tidak terdapat komplikasi berupa perdarahan subdural. Tidak terdapat hubungan bermakna antara karakteristik subjek dan angka kejadian komplikasi pascaoperasi VP shunt dengan menggunakan pompa INA shunt. Kesimpulan : Angka komplikasi operasi VP Shunt menggunakan sistem pompa INA Shunt adalah minimal. Sistem pompa INA Shunt dapat digunakan untuk operasi VP Shunt pada pasien anak dengan hidrosefalus dan variasinya.
Background: Hydrocephalus is a condition of excessive accumulation of cerebrospinal fluid (CSF) caused by an imbalance between the production and absorption of CSF, resulting in ventriculomegaly and can be accompanied by an increase in intracranial pressure. One of the most common treatments for hydrocephalus is VP Shunt, which also carries a risk of complications. Indonesia has been able to make its own pump system for VP Shunt operation under the name INA-shunt. Several studies have investigated the complication rate of VP shunt in pediatric patients, but none has investigated the complication rate with the use of the INA-shunt pump system. Objective: To determine the complications that occur in pediatric patients with hydrocephalus and its variations who have had VP Shunt surgery with an INA Shunt pump and the factors that influence it. Methods: This research is descriptive retrospective. The research is multicenter, taking secondary data from Cipto Mangunkusumo General Hospital, Harapan Kita Hospital, and Sardjito Hospital. In the period January 2018 – December 2019, there were 31 subjects that met the inclusion and exclusion criteria. Postoperative clinical and radiological assessments were performed within 1 year to evaluate the presence of complications in the subjects.
Results: From 31 subjects, there were complications in 5 subjects (16%). The complications were proximal shunt malfunction (10%, n=3), exposed shunt (3%, n=1), and infected shunt (3%, n=1). All complications occurred in patients < 3 months of age at the time of VP shunt and 80% of complications occurred < 6 months postoperatively. There were no complications such as subdural hemorrhage. There is no significant relationship between the characteristics of the subject and the incidence of postoperative VP shunt complications using an INA shunt pump. Conclusion: The complication rate of VP Shunt operation using the INA Shunt pump system is minimal. The INA Shunt pump system can be used for VP Shunt surgery in pediatric patients with hydrocephalus and its variations."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2021
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Jelita Amanda
Perbedaan konsentrasi receptor activator of NFkB ligand (RANKL) pada pasien ortodontik yang menggunakan sistem self-ligating pasif dengan sistem pre-adjusted edgewise appliance = RANKL concentrations in early orthodontic treatment using passive self ligating and preadjusted edgewise appliance bracket systems
"Receptor activator of nuclear factor kappa B ligand RANKL merupakan sitokin yang berperan dalam remodeling tulang sebagai pembentuk osteoklas. Dalam fase pergerakan gigi osteoklas berfungsi untuk meresorbsi daerah hialinisasi pada tulang alveolar sehingga tercipta pergerakan gigi. Tujuan dari penelitian ini adalah untuk mengetahui perbedaan konsentrasi RANKL antara perawatan ortodontik cekat yang menggunakan sistem breket pre-adjusted edgewise appliance PEA dan breket self-ligating SL dalam gingival crevicular fluid GCF . Subjek penelitian terdiri dari tiga kelompok yang dibagi menjadi dua kelompok eksperimental dan satu kelompok kontrol, pengambilan GCF pada subjek penelitian dilakukan sebelum perawatan TO , 1 jam setelah pemasangan T1 , 24 jam T2 dan 168 jam T3 setelah pemasangan bracket. Enzyme-linked immunosorbent assay ELISA kit digunakan untuk mengetahui konsentrasi RANKL pada GCF. Pada penelitian ini terdapat perbedaan nilai rerata konsentrasi RANKL pada kelompok sistem braket SL pasif dan sistem braket PEA pada 1 jam, 24 jam dan 168 jam setelah pemasangan alat ortodonti. Nilai rerata konsentrasi RANKL pada sistem braket SL pasif lebih tinggi dibandingkan kelompok sistem braket PEA dikarenakan adanya perbedaan sistem gaya dan mekanoterapi pada braket SL. Result, Conclusion
The receptor activator of nuclear factor kappa B ligand RANKL is a cytokine that helps remodel bone by forming osteoclasts. During tooth movement phases, osteoclasts resorb the hyalinization areas of alveolar bone, triggering tooth movement. The aim of this study was to determine the differences in the RANKL concentrations in early orthodontic treatment between preadjusted edgewise appliance PEA and self ligating SL bracket systems. Gingival crevicular fluid was retrieved before treatment and 1 hour, 24 hours, and 168 hours after treatment from five maxillary anterior proximal sites on the mesiolabial side of the upper right to left canines. An enzyme linked immunosorbent assay was used to determine the RANKL concentrations. The results showed differences in the RANKL concentrations between the SL and PEA groups 1 hour, 24 hours, and 168 hours after the bracket insertion. The RANKL concentration at 168 hours in the SL group was higher when compared to the PEA group, whereas that in the PEA group decreased to the baseline value after 24 hours. The RANKL concentration in the passive SL bracket system was higher when compared to the PEA system due to differences in the force and mechanotherapy of the SL brackets."
Depok: Fakultas Kedokteran Gigi Universitas Indonesia, 2017
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Laksmi Trisasmita
Hubungan Kualitas Diet menggunakan Heallthy Eating Index (HEI) dengan Kejadian Stunting pada Anak Balita usia 12-59 bulan di Kabupaten Bogor Tahun 2019 = Quality of diet using Modifed Healthy Eating Index (HEI) associated with Stunting Children aged 12-59 months in Bogor Regency, 2019.
"Praktik pemberian makan yang memiliki kualitas baik berdasarkan pedoman masih jauh dari optimal di beberapa negara berkembang. Bukti mengenai hubungan kualitas makanan dengan status gizi sangat beragam. Beberapa penelitian sebelumnya menggunakan HEI sebagai indikator menentukan kualitas diet anak. Berdasarkan laporan Riskesdas tahun 2018, Indonesia merupakan negara urutan keempat dengan prevalensi stunting yang tertinggi di dunia (30,8%). Penelitian ini dilakukan untuk mengetahui gambaran dan hubungan antara kualitas diet menggunakan modifikasi HEI dengan kejadian stunting pada balita usia 12-59 bulan di Kecamatan Babakan Madang, Kabupaten Bogor. Desain penelitian yang digunakan adalah cross sectional. Sampel pada penelitian ini berjumlah 458 balita. Penelitian ini dilakukan pada bulan Mei sampai Agustus 2019. Pengumpulan data dilakukan dengan pengukuran tinggi badan, panjang badan, wawancara dengan kuesioner dan lembar recall 1x24 jam. Analisis data dilakukan dengan uji chi square. Hasil penelitian menunjukkan bahwa prevalensi stunting usia 12-59 bulan di Kecamatan Babakan Madang sebesar 44,8% berdasarkan TB/U. Analisis uji statistik menunjukkan hubungan yang bermakna antara panjang lahir setelah dikontrol dengan berat lahir, kualitas diet (OR: 9,72, 95%CI 2,39-19,6, p<0,05), dan asupan protein dengan kejadian stunting. Komponen yang paling dominan pada HEI dengan kejadian stunting adalah keragaman pangan (OR: 2,0, 95% CI 1,23-3,24, p<0,05).
Good quality feeding practices based on guidelines are far from optimal in some developing countries. Evidence regarding the quality of diet with nutritional status has been diverse, but no information is available to link diet quality and stunting in childhood that researcher found. Some previous studies using HEI as an indicator determine the quality of children’s diet. Based on Basic National Survey Report (Riskesdas) in 2018, Indonesia has the world’s fourth highest incidence of stunting (30,8%). This study was conducted to determine the description and association between diet quality using modified HEI with the incidence of stunting in children aged 12-59 months in Babakan Madang District, Bogor Regency. Cross sectional design was used in this study. The sample in this study were 458 children aged 12-59. This study was conducted in May to August 2019. Data collection was carried out by measuring height, body length, interview with questionnaire and 1x24 hours recall sheet. The results showed that the prevalence of stunting based on height-for-age at 12-59 months in Babakan Madang district was 44.8%. Statistical analysis showed that the relationship was described between birth length after being controlled with birth weight, diet quality (OR: 9,72, 95% CI 2.39-19.6, p <0.05), and protein intake with stunting. The most dominant component of HEI towards stunting incidence was dietary diversity (OR: 2.0, 95% CI 1.23-3.24, p <0.05)."
Depok: Fakultas Kesehatan Masyarakat Universitas Indonesia, 2021
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Michael Caesario
Prevalensi serta karakteristik yang memengaruhi kejadian dialisis peritoneal pascaoperasi pada pasien bayi yang menjalani operasi jantung kongenital = Prevalence and characteristics affecting postoperative peritoneal dialysis among babies underwent congenital heart surgery
"ABSTRAK
Latar belakang : Dialisis peritoneal (DP) merupakan modalitas terapi pengganti ginjal utama pada pasien bayi yang menjalani operasi jantung kongenital. Penelitian ini bertujuan untuk mengetahui prevalensi DP pascaoperasi serta menilai pengaruh karakteristik lama penggunaan mesin pintas jantung paru, kompleksitas operasi, usia, dan berat badan terhadap kejadian dialisis peritoneal pascaoperasi pada pasien bayi yang menjalani operasi jantung kongenital dengan mesin pintas jantung paru.
Metode : Dilakukan suatu studi cross sectional pada pasien bayi yang menjalani operasi koreksi penyakit jantung kongenital di Rumah Sakit Jantung Harapan Kita dalam periode 1 Januari hingga 31 Desember 2018. Analisis statistik dilakukan pada faktor lama penggunaan mesin pintas jantung paru, kompleksitas operasi menurut kategori Risk Adjustment for Congenital Heart Surgery, usia, dan berat badan untuk menilai pengaruh faktor-faktor tersebut terhadap kejadian DP pascaoperasi.
Hasil : Sebanyak 181 pasien dilibatkan sebagai sampel penelitian. DP pascaoperasi dilakukan pada 13 (7,2%) pasien. Kelompok pasien yang menjalani DP memiliki median lama penggunaan mesin pintas jantung paru yang lebih tinggi (155 (44 - 213) vs 95,5 (13 - 279) menit; p = 0,008), rerata usia yang lebih muda (53 ± 54,79 vs 162 ± 88,59 hari; p < 0,001), serta median berat badan yang lebih rendah (3,6 (2,8 -4,5) vs 4,65 (2,6 - 11) kg; p < 0,001). Sebaran kompleksitas operasi antar kelompok yang tidak dilakukan DP dan kelompok yang dilakukan DP tidak berbeda bermakna (p = 0,11). hanya faktor lama penggunaan mesin pintas jantung paru > 90 menit yang secara bermakna memengaruhi kejadian DP (rasio odds 5,244 (1,128 - 24,382); p 0,02).
Simpulan : Prevalensi DP pascaoperasi adalah 7,2 %. Kelompok pasien yang menjalani DP pascaoperasi memiliki usia yang lebih muda, berat badan yang lebih rendah, dan lama penggunaan mesin pintas jantung paru yang lebih lama dibanding kelompok pasien yang tidak menjalani DP pascaoperasi. Penggunaan mesin pintas jantung paru > 90 menit memengaruhi kejadian DP pascaoperasi secara bermakna.
ABSTRACT
Introduction: Peritoneal dialysis (PD) is the method of choice for renal replacement therapy in babies underwent congenital heart surgery. This study aimed to asses the prevalence of postoperative PD and to examine the influence of cardiopulmonary bypasss (CPB) time, surgical complexity, age, and body weight to the occurence of postoperative PD among babies underwent congenital heart surgery with CPB.
Method: a cross sectional study was done on babies underwent congenital heart surgery in National Cardiovascular Center Harapan Kita from January 1st until December 31st 2018. Statistical analysis was done to CPB time, surgical complexity as classified according to Risk Adjusment for Congenital Heart Surgery categories, age, and body weight in order to asses the influence of those factors to the occurence of postoperative PD.
Results: one hundred and eighty one patients were included in the study. Postoperative PD was done in 13 (7,2%) patients. Postoperative PD group showed longer median CPB time (155 (44 - 213) vs 95,5 (13 - 279) minutes; p = 0,008), younger mean age (53 ± 54,79 vs 162 ± 88,59 days; p < 0,001), and lower median body weight (3,6 (2,8 -4,5) vs 4,65 (2,6 - 11) kg; p < 0,001). Distribution of surgical complexity between postoperative PD group and no postoperative PD group was not differ significantly (p = 0,11). Only CPB time > 90 minutes that significantly affect the occurence of postoperative PD (odds ratio 5,244 (1,128 - 24,382); p 0,02).
Conclusion: The prevalenve of postoperative PD was 7,2%. Patients underwent postoperative PD tend to be younger, had lower body weight, and had longer CPB time compared to those who did not underwent postoperative PD. CPB time > 90 minutes significantly affect the occurence of postoperative CPB."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2019
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Veronica Crassnaya Angel
Analisis Mutu Pelayanan Telemedicine Bagi Pasien Positif COVID-19 Di Jabodetabek Yang Melakukan Isolasi Mandiri: Menggunakan Pendekatan E-SERVQUAL = Telemedicine Service Quality Analysis For Positive COVID-19 Self Isolated Patient In Jabodetabek: Using E-SERVQUAL Approach
"Latar Belakang: Sejak pandemi Covid-19, pelaksanaan layanan imunisasi dasar anak mengalami penurunan. WHO menyebutkan secara global, sebanyak 23 juta anak di bawah umur satu tahun tidak menerima imunisasi dasar di tahun 2020. Sedangkan di Jawa Barat, cakupan imunisasi anak menurun sebesar 93,74 % tahun 2019, menjadi sebesar 82,26% tahun 2020. Oleh karena itu penting untuk mengkaji faktor-faktor yang mempengaruhi imunisasi dasar bayi. Tujuan penelitian ini adalah untuk mengetahui determinan cakupan imunisasi dasar lengkap pada bayi yang lahir di masa pandemi covid-19 di provinsi jawa barat. Metode : Penelitian ini menggunkan data SUSENAS 2021 di Jawa Barat dengan sampel sebanyak 368 bayi berusia 10-12 bulan yang lahir di masa pandemi covid-19. Penelitian ini menggunakan desain potong lintang (cross- sectional) dengan analisis regresi logistik berganda. Hasil : Berdasarkan analisis regresi logistik, faktor yang berhubungan terhadap imunisasi dasar lengkap bayi 10-12 bulan yang lahir di masa pandemi covid-19 di Jawa Barat tahun 2021 adalah pendidikan terakhir ibu, status pekerjaan ibu, status ekonomi, kepemilikan asuransi kesehatan, dan kepemilikan buku KIA dan faktor yang tidak berhubungan adalah umur ibu, tempat tinggal, penolong persalinan, tempat persalinan, akses internet. Faktor yang paling dominan berhubungan terhadap imunisasi dasar lengkap bayi adalah kepemilikan buku KIA (p value = 0.00 ; AOR =16,064 ; 95% CI =6.397-40.339). Kesimpulan : Pemerintah dapat mengoptimalkan pemanfaatan buku KIA dengan mengembangkan digitalisasi buku KIA skala nasional. Puskesmas dapat bekerja sama dengan berbagai pihak, terutama kader untuk memotivasi keluarga/masyarakat supaya memanfaatkan dan menerapkan isi buku KIA dalam perawatan kesehatan ibu dan anaknya.
Background: Since the Covid-19 pandemic, the implementation of basic childhood immunization services has decreased. WHO said globally, as many as 23 million children under the age of one year did not receive basic immunizations in 2020. Meanwhile in West Java, child immunization coverage decreased by 93.74% in 2019, to 82.26% in 2020. it is important to examine the factors that influence infant basic immunization. The purpose of this study was to determine the determinants of complete basic immunization coverage for infants born during the COVID-19 pandemic in West Java province. Methods: This study uses SUSENAS 2021 data in West Java with a sample of 368 infants aged 10-12 months who were born during the COVID-19 pandemic. This study used a cross-sectional design with multiple logistic regression analysis. Results: Based on logistic regression analysis, factors related to complete basic immunization of 10-12 month babies born during the COVID-19 pandemic in West Java in 2021 were the mother's last education, mother's employment status, economic status, health insurance ownership, and ownership. MCH handbook and unrelated factors are maternal age, place of residence, birth attendant, place of delivery, internet access. The most dominant factor related to complete basic immunization of infants was ownership of the MCH handbook (p value = 0.00 ; AOR = 16,064 ; 95% CI = 6,397-40,339). Conclusion: The government can optimize the use of MCH books by developing the digitization of MCH books on a national scale. Puskesmas can work together with various parties, especially cadres to motivate families/communities to use and apply the contents of the MCH handbook in maternal and child health care."
Depok: Fakultas Kesehatan Masyarakat Universitas Indonesia, 2022
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UI - Tesis Membership  Universitas Indonesia Library
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