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"Reliable knowledge discovery focuses on theory, methods, and techniques for RKDD, a new sub-field of KDD. It studies the theory and methods to assure the reliability and trustworthiness of discovered knowledge and to maintain the stability and consistency of knowledge discovery processes. RKDD has a broad spectrum of applications, especially in critical domains like medicine, finance, and military."

"ABSTRACTVirtual screening (VS) is a computational technique used in drug discovery. Virtual Screening process usually works by identifying structures that are most likely to bind the target of drug. Virtual screening is usually based on compound similarity or database docking. Thus, the identification for drugcompounds based on structure classification still remain as a challenging task. The purpose of this research is to find a new approach for ligand-based virtual screening using machine learning technique. In this paper, theclassification has been done by using Deep Belief Networks (DBN) method. The data from Nicotinamide Adenine Dinucleotide (NAD) protein target family were used for training and testing the model. This research used four protein target classes from literature and two protein target classes from DUD-E docking website. Feature were obtained from molecular fingerprint descriptor. The experiments result show that DBN method outperform the existing pharmacophore approach."

"Penelitian-penelitian sebelumnya menemukan bahwa skeptisisme sains dipengaruhi oleh berbagai hal seperti konservatisme politik, religiusitas, literasi sains, dan kepercayaan terhadap sains. Namun, pengaruh kepercayaan sekuler masih belum banyak diteliti dan penelitian yang ada memperlakukan kepercayaan sekuler sebagai kebalikan dari religiusitas. Disamping itu, mekanisme dari hubungan kedua variabel itu belum diketahui. Oleh karena itu, penelitian ini dilakukan dengan tujuan melihat pengaruh kepercayaan sekuler terhadap skeptisisme sains dengan mediasi literasi sains dan kepercayaan terhadap sains. Partisipan merupakan 202 warga negara Indonesia (95 laki-laki, 101 perempuan, 6 memilih tidak menjawab; M=32,25 tahun, SD=11,823). Penelitian ini menemukan bahwa kepercayaan terhadap sains memediasi pengaruh ketiga dimensi kepercayaan sekuler terhadap skeptisisme sains, yaitu dimensi pertama (b=0,289, p=0,005; b=-0,287, p=0,000), dimensi kedua (b=0,378, p=0,000; b=-0,258, p=0,000), dan dimensi ketiga (b=0,440, p=0,000; b=-0,306, p=0,041). Sementara itu, literasi sains hanya memediasi dimensi ketiga (b=-0,041, p=0,005; b=-0,444, p=0,044). Artinya, pengaruh kepercayaan sekuler terhadap skeptisisme sains lebih kuat dimediasi oleh kepercayaan terhadap sains, dibandingkan dengan literasi sains.

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Previous studies have found that scientific skepticism is influenced by various things such as political conservatism, religiosity, scientific literacy, and belief in science. However, the effect of secular belief has not been studied much and the existing research treats secular belief as the opposite of religiosity. In addition, the mechanism of the relationship between the two variables is not yet known. Therefore, this research was conducted with the aim of looking at the effect of secular belief as a predictor of scientific skepticism with the mediation of scientific literacy and belief in science. Participants were 202 Indonesian citizens (95 males, 101 females, 6 chose not to answer; M=32.25 years, SD=11.823). This study found that belief in science mediates the effect of the three dimensions of secular belief on scientific skepticism, namely the first dimension (b=0.289, p=0.005; b=-0.287, p=0.000), the second dimension (b=0.378, p=0.000; b=-0.258, p=0.000), and the third dimension (b=0.440, p=0.000; b=-0.306, p=0.041). Meanwhile, scientific literacy only mediated the third dimension (b=-0.041, p=0.005; b=-0.444, p=0.044). This means that the influence of secular belief on scientific skepticism is more strongly mediated by belief in science, compared to scientific literacy."

"Penelitian ini membahas dua persoalan dalam manajemen kontemporer. Pertama, penerapan realisme kritis terhadap cara kita memandang realitas organisasi. Kedua, menyelidiki bagaimana pendekatan positivisme dalam pemodelan matematika dan statistik dapat menyederhanakan isu-isu kompleks dalam penelitian manajemen. Hingga saat ini, manajemen masih dipertanyakan sebagai ilmu, sementara yang lain, menganggapnya sebagai seni. Realisme kritis menawarkan pendekatan alternatif teoritis yang memungkinkan adanya ilmu dalam ilmu sosial, khususnya manajemen melalui dimensi transitif dan intransitif. Dengan menerapkan realisme kritis, implikasinya, memungkinkan peneliti untuk memfokuskan pada konteks di mana studi organisasional dipelajari dan memungkinkan perubahan preskriptif dalam suatu penelitian. Penelitian ini menemukan bahwa; pertama, pendekatan positivisme dengan pemodelan matematis dan statistik merupakan pendekatan dominan dalam penelitian manajemen. Kedua, pendekatan positivisme memiliki keterbatasan atau masalah ‘prediktabilitas’, karena melakukan peramalan dalam penelitian sosial, konsekuensinya melakukan ‘closed system’, padahal, melakukan generalisasi-universal dari partikularitas tidak dapat dilakukan pada observasi yang terbatas. Peneliti tidak dapat melalukan konjungsi konstan di antara peristiwa ‘yang sosial’ (aktivitas manusia), karena observasi dan eksperimen ‘sosial’, bagi Bhaskar, adalah manipulasi ilmiah. Konsekuensinya, kompleksitas isu-isu manajemen tereduksi, dan mempengaruhi pemahaman kita tentang manajemen sebagai ilmu secara keseluruhan.

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This research explores two pivotal issues in contemporary management. Firstly, it examines the application of critical realism in conceptualizing organizational reality. Secondly, the study investigates the role of a positivist approach in simplifying complex management issues through mathematical and statistical modeling. Management, to date, oscillates between being perceived as a science and an art. Critical realism proposes an alternative theoretical framework, facilitating a scientific approach within social sciences, particularly in management. This is achieved through the integration of transitive and intransitive dimensions. The application of critical realism allows researchers to concentrate on the specific contexts of organizational studies, enabling prescriptive changes. The findings of this research are twofold. First, it identifies the dominance of a positivist approach with mathematical and statistical modeling in management research. Second, it highlights the limitations and predictability challenges inherent in positivism. This approach leads to a 'closed system' in social research, where generalizing universally from specific observations is problematic due to limited empirical evidence. According to Bhaskar, the inability to consistently link social events (human activities) arises from the nature of social observation and experimentation as a form of scientific manipulation. Consequently, this reductionist approach simplifies the complexity of management issues, impacting the understanding of management as a scientific discipline."