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"Patient satisfaction was one thing that was very important in reviewing the quality of health services, including health center. Measuring patient satisfaction can be used to evaluate the quality of health services. In this study the dimensions related to health service user satisfaction, were in terms of reliability, assurance, tangible, emphaty and responsiveness. The purpose of this research was to know the level in district of outpatient services and inpatient care at district health center Sidoarjo."

"Acute Kidney Injury (AKI) merupakan komplikasi serius yang umum terjadi pada pasien rawat inap. Berdasarkan penelitian tahun 2005, terjadi peningkatan insiden dan keparahan AKI hingga 50% akibat penggunaan obat selama rawat inap. Salah satu tugas apoteker di RS adalah melakukan pemantauan terapi obat, terdapat beberapa obat di RSUI yang dinilai mampu menginduksi terjadinya AKI. Oleh karena itu, dilakukan pembuatan daftar obat yang dapat menginduksi terjadinya AKI serta studi kasus terjadinya AKI pada pasien rawat inap akibat penggunaan obat di RSUI pada bulan Maret 2023. Daftar obat penginduksi AKI dibuat berdasarkan studi literatur dari pustaka tahun 2005 – 2023 kemudian obat dikategorikan berdasarkan kelas terapi obat. Sedangkan, studi kasus dilaksanakan secara retrospektif menggunakan data sekunder pasien rawat inap RSUI pada bulan Maret 2023 yaitu rekam medis salah satu pasien yang memenuhi kriteria inklusi dan eksklusi. Terdapat 26 obat yang mampu menginduksi AKI di RSUI. Berdasarkan studi kasus, terapi ramipril diduga mampu meningkatkan risiko terjadinya AKI pada salah satu pasien RSUI yang dinilai berdasarkan peningkatan nilai serum kreatinin dan penurunan nilai GFR. Ramipril diduga menjadi penyebab peningkatan risiko terjadinya AKI berdasarkan angka prevalensinya sebesar 28%, adanya riwayat perbaikan fungsi ginjal saat penghentian obat, serta fungsi ginjal yang kembali memburuk ketika terapi ramipril kembali dilanjutkan. Penilaian kondisi pasien menggunakan instrumen naranjo dibutuhkan untuk mengonfirmasi insiden terjadinya AKI akibat ramipril.

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Acute Kidney Injury (AKI) was a serious complication that commonly occurs in inpatients. Based on a study in 2005, there was an increase in the incidence and severity of AKI up to 50% due to drug induce during hospitalization. One of the responsibilities of the pharmacist in the hospital was to perform drug therapy monitor and several drugs in RSUI were considered likely to induce AKI. Therefore, a list of drugs induced AKI was created, and a case study of drug-induced AKI in hospitalized patients at RSUI in March 2023 was performed. The list of drugs induced AKI was made based on a literature study from 2005 – 2023, then the drugs were categorized based on the drug therapy class. Meanwhile, the case study was carried out retrospectively using secondary data from hospitalized patients at RSUI in March 2023, which was the medical records from one of the patients who met the inclusion and exclusion criteria. There are 26 drugs-induced AKI in RSUI. Based on the case study, ramipril therapy was thought to be likely to increase the risk of developing AKI in one of the RSUI patients as assessed by the increase of creatinine serum and the decrease GFR values. Ramipril is thought to be the cause of the increased risk of AKI based on its prevalence rate which was 28%, history of improvement in kidney function when stopping the drug, and worsened kidney function when ramipril therapy is resumed. Assessment of the patient's condition using the Naranjo instrument is needed to confirm the incidence of AKI due to ramipril."

"Kanker merupakan penyakit yang dapat memberikan efek negatif pada fungsi tubuh sehingga mempengaruhi kualitas hidup. Kualitas hidup dapat diukur dengan berbagai macam instrumen. Tujuan: menelaah hasil penelitian mengenai perbandingan skoring kualitas hidup pasien kanker menggunakan EORTC QLQ-C30 dengan FACT-G. Metode : literature review dengan PRISMA checklist sebagai protokol. Analisis bias menggunakan Joanna Briggs Institute (JBI) Critical Appraisal. Pencarian artikel dilakukan Mei-Juli 2020, menggunakan database ClinicalKey, EBSCOhost, Google Scholar, ProQuest, dan PubMed. Dari 1.194 artikel ditemukan, sebanyak 17 artikel sesuai kriteria inklusi. Hasil : skor QoL FACT-G lebih tinggi dibandingkan EORTC QLQ-C30. Selain itu, pada dimensi kualitas hidup dan fisik menunjukkan hubungan yang kuat (r= 0.54-0.76), namun lemah pada dimensi sosial (r=0.00-0.130). Penelitian ini merekomendasikan FACT-G sebagai instrumen yang mengukur QoL secara holistik serta berfokus pada psikososial.

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Cancer is a disease that can hurt bodily functions that affect the quality of life. Quality of life can be measured by a variety of instruments. Objective: To examine the results of research on the comparison of quality of life scoring in cancer patients using EORTC QLQ-C30 with FACT-G. Methods: A literature review with the PRISMA checklist as a protocol. Biased analysis using the Joanna Briggs Institute (JBI) Critical Appraisal. Search for articles was conducted from May to July 2020, using the ClinicalKey, EBSCOhost, Google Scholar, ProQuest, and PubMed databases. From 1,194 articles found, 17 articles were, according to the inclusion criteria. Result: QoL FACT-G score was higher than the EORTC QLQ-C30. Besides, the quality of life and physical dimensions showed a strong relationship (r = 0.54-0.76), but weak in the social dimension (r = 0.00-0.130). This study recommends FACT-G as an instrument that measures QoL holistically and focuses on psychosocial."

"ABSTRAKPendahuluan: Alfa fetoprotein AFP merupakan penanda tumor yang mengalami peningkatan pada karsinoma hepatoselular KHS namun dapat juga normal pada 40 kasus. Peningkatan AFP dikatakan menghasilkan diferensiasi tumor yang buruk. Kasus KHS yang datang ke RSCM cenderung lanjut dengan karakteristik tersendiri. Penelitian ini bertujuan menilai korelasi AFP terhadap derajat diferensiasi KHS di RSCM.Metode: Data 32 kasus KHS di RSCM yang dilakukan hepatektomi dikumpulkan secara retrospektif dari 2010-2016. Data dasar karakteristik pasien dinilai berdasarkan nilai AFP dan derajat diferensiasi. Lalu dilakukan analisis untuk melihat korelasi nilai AFP dengan derajat diferensiasi KHS.Hasil: Nilai rata-rata AFP adalah 20183 ng/mL, usia 51,75 tahun, 81 kasus terjadi pada laki-laki, 59,4 berdiferensiasi buruk, 50 berukuran >5-10 cm, 50 kasus sirosis, dan 68,8 terdapat invasi pembuluh darah. Diferensiasi buruk 42 pada laki-laki, 47,4 pada HbsAg positif, 50 pada Anti HCV positif, 31,2 sirosis, dan 40,9 mengalami invasi pembuluh darah. Nilai AFP 20 ng/mL 42,1 berdiferensiasi buruk. Pada analisis orelasi didapatkan r=0,203 dengan p>0,05.Kesimpulan: AFP tidak dapat memprediksi derajat diferensiasi karsinoma hepatoseluler pada karakteristik kasus KHS di tempat kami.

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ABSTRACT<>br>Background AFP is a tumor marker which is increased in HCC, but might be found normal in 40 cases. Increased AFP implies a worsen tumor differentiation. Correlation between AFP with HCC managed in RSCM Ciptomangunkusumo hospital remains unclear. This study aimed to find the correlation between histological differentiation grade of HCC and AFP serum level.Method A total of 32 of HCC cases following hepatectomy in RSCM during 2010 2016 were enrolled in a retrospective study. Subject characteristics, AFP levels and histological differentiation grade were the variables in this study, and subjected to statistical analysis. Significancy found if p 5 10cm in diameter, 50 subjects were cirrhotic, and 68.8 subjects with microvascular invasion. AFP level found in range of 0.5 400000 ng mL 20183 SD75580.08 . Among all the subjects 12.5 were well differentiated, 28.1 were moderate differentiated, and 59.4 were poorly differentiated. AFP level 20ng mL was 42.1 . Correlation analysis revealed an r 0.203 with p 0.05.Conclusion There is no correlation between AFP serum level and histological differentiation grade of HCC in our study"

"ABSTRAKPenting bagi perawat untuk melakukan penilaian dan mengevaluasi kondisi pasien kanker, salah satunya dengan mengukur kualitas hidup mereka. Tujuan dari telaah literatur ini adalah untuk mengidentifikasi perbandingan hasil pengukuran kualitas hidup pada pasien kanker dengan menggunakan EORTC QLQ-C30 dan WHOQOL-BREF. Metode: Menggunakan prinsip PRISMA dengan mencari jurnal melalui basis data CINAHL, Google Scholar, ProQuest, dan PubMed yang dilakukan dari bulan Juni-Juli 2020. Pencarian artikel dibatasi dari tahun 2010-2020. Penilaian kualitas artikel jurnal menggunakan Joanna Briggs Institute (JBI) checklist untuk mengurangi risiko bias. Hasil: Dari 955 jurnal yang ditemukan, terdapat 14 jurnal yang sesuai dengan kriteria penelitian. Skor kualitas hidup yang diukur dengan EORTC QLQ-C30 lebih tinggi daripada yang diukur dengan WHOQOL-BREF. EORTC QLQ-C30 dan WHOQOL-BREF memiliki aspek pengukuran yang berbeda. Peneliti merekomendasikan untuk menggunakan EORTC QLQ-C30 dalam mengukur kualitas hidup pada pasien kanker.

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ABSTRACTNurses need to carry out assessments and evaluate the condition of cancer patients, one of them by measuring their quality of life. The aim of this literature review is to identify the comparison of the results of measurements of quality of life in cancer patients using EORTC QLQ-C30 and WHOQOL-BREF. Method: Using the PRISMA principle by searching journals through databases from ProQuest, CINAHL, Google Scholar, ProQuest, and PubMed conducted from June-July 2020. Article search is limited from 2010-2020. Assessment of journal article quality using the Joanna Briggs Institute (JBI) checklist to reduce the risk of bias. Results: Of 955 journals found, 14 journals fit the research criteria. The quality of life score measured by EORTC QLQ-C30 is higher than that measured by WHOQOL-BREF. EORTC QLQ-C30 and WHOQOL-BREF have different measurement aspects. It is recommended using the EORTC QLQ-C30 to measure the quality of life in cancer patients."

"Pasien ESRD yang menjalani hemodialisis merupakan kelompok yang rentan terkena infeksi di masa pandemi ini. Ketika pasien terkonfirmasi COVID-19, pasien harus menjalani isolasi dan hemodialisis di unit khusus COVID-19. Akan muncul berbagai respon dan dampak bagi pasien. Tujuan penelitian ini adalah untuk mengeksplorasi secara mendalam tentang pengalaman pasien yang menjalani hemodialisis dan terkonfrimasi COVID-19. Penelitian ini menggunakan pendekatan fenomenologi dengan metode wawancara mendalam. Partisipan berjumlah 15 orang dari RS Universitas Hasanuddin yang dipilih melalui teknik purposive sampling. Terdapat 5 tema yang dihasilkan dalam penelitian ini yaitu respon emosi saat terkonfirmasi COVID-19, dampak yang dialami pasien saat terkonfirmasi COVID-19 dan menjalani isolasi, perbedaan yang dialami saat menjalani isolasi dan HD COVID-19, support system dan harapan terhadap ruang perawatan isolasi dan HD COVID-19. Temuan tersebut menunjukkan bahwa pasien yang menjalani hemodialisis dan terkonfirmasi COVID-19 memerlukan bantuan dan dukungan dari penyedia layanan kesehatan di unit hemodialisis khususnya unit hemodialisis khusus COVID-19 untuk mengatasi berbagai masalah dan dampak akibat terkonfirmasi. Perawat perlu berperan aktif untuk melakukan pengkajian secara holistik dan evaluasi secara terus menerus dan berkelanjutan agar dapat memberikan asuhan keperawatan yang komprehensif dalam memenuhi kebutuhan pasien

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Hemodialysis patients were a susceptible group to get infection during pandemic. When a patient was confirmed COVID-19, the patient must undergo isolation and hemodialysis in a special COVID-19 unit. There would be various responses and impacts for the patient. The purpose of this study was to explore in depth the experiences of patients undergoing hemodialysis and confirmed COVID-19. This study used a phenomenological approach with in-depth interviews. There were 15 participants from Hasanuddin University Hospital who were selected through purposive sampling technique. There are 5 themes generated in this study, emotional responses when confirmed COVID-19, the impact experienced by patients when confirmed COVID-19 and undergoing isolation, differences experienced when undergoing isolation and HD COVID-19, support system and expectations for the isolation room.and HD COVID-19. These findings indicate that patients undergoing hemodialysis and confirmed COVID-19 require assistance and support from health care providers in the hemodialysis unit, especially in the COVID-19 hemodialysis unit for to overcome various problems and impacts of being confirmed. Nurses need to play an active role in conducting holistic assessments and evaluations continuously in order to provide comprehensive nursing care in meeting patient needs."

"AV fistula allows external vascular access for hemodialysis patients. Because hemodialysis patients experience puncture wounds and stabbing pain approximately 300 times a year, development of methods to decrease pain intensity are of great importance. Some techniques, such as the Valsalva maneuver, are known to reduce pain. This study aims to assess the effect of the Valsalva maneuver on decreasing the intensity of AV fistula pain in patients receiving hemodialysis. The quasi-experimental research of pre and post without control applying consecutive sampling to get as many as 63 respondents. Pain intensity was measured by using the Numerical Pain Rating Scale (NPRS). The Valsalva maneuver was performed during insertion of the AV fistula needle for 16–20 seconds. The results showed significant differences in pain intensity between before and after the intervention with the difference in mean that is 1.35 (SD = 0.54), t = 19.70, p = 0.001. The Valsalva maneuver is effective in reducing the pain of AV fistula insertion because it stimulates the vagus nerve to induce an antinociceptive effect. Nurses are highly recommended to teach the Valsalva maneuver to patients undergoing routine hemodialysis."

"Background: arterial stiffness is a mortality predictor in hemodialysis patients, hemodialysis induces inflammation, marked by an intradialysis increase in the inflammatory marker pentraxin 3 (PTX3). Arterial stiffness in twice-weekly hemodialysis patients in Indonesia is lower than has been found in studies of thrice-weekly patients. This study therefore aims to determine the factors associated with arterial stiffness, focusing on the role of hemodialysis frequency and PTX3. Methods: a cross-sectional study was conducted at Cipto Mangunkusumo Hospital, Fatmawati Hospital, and Medistra Hospital involving patients with twice- and thrice-weekly hemodialysis. Arterial stiffness was measured by carotid-femoral pulse wave velocity after hemodialysis, and blood samples for PTX3 testing were taken before hemodialysis. Bivariate and multivariate analyses were performed using chi-squared tests and logistic regression. Results: out of 122 subjects, 82 underwent twice-weekly hemodialysis. There was no difference in arterial stiffness between patients with twice- and thrice-weekly hemodialysis. In bivariate analysis, PTX3, cardiovascular disease, dialysis vintage had p values of <0.05, while the subsequent multivariate analysis showed that PTX3>2.3 ng/ml was associated with arterial stiffness (adjusted OR 5.18; 95% CI 1.07–24.91), as well as cardiovascular disease (adjusted OR 3.67; 95% CI 1.40–10.55), LDL (adjusted OR 3.10; 95% CI 1.04–9.24), and dialysis vintage (adjusted OR 2.72; 95% CI 1.001–7.38). Conclusion: predialysis PTX3 levels above 2.3 ng/ml were associated with arterial stiffness. There was no difference in arterial stiffness between patients with twice- and thrice-weekly hemodialysis."