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"Gli esseri umani sopravvivono 40 giorni senza mangiare, 4 giorni senza bere ma solo 4 minuti senza respirare: una proporzione che dice tutto sull’importanza della respirazione. L’aria inspirata è filtrata, riscaldata e umidificata dal naso, meccanismo che protegge l’albero respiratorio da un flusso d’aria eccessivo. È quindi cruciale ristabilire una corretta funzionalità nasale.Questo volume, dedicato a otorinolaringoiatri, chirurghi plastici e maxillofacciali, descrive la turbinoplastica inferiore modificata, un nuovo approccio chirurgico a numerosi problemi associati all’ipertrofia dei turbinati inferiori. La maggior parte delle tecniche chirurgiche oggi diffuse, infatti, tratta solo la parte molle di queste strutture ossee con procedimenti che spesso conducono a recidive. Con questa tecnica, invece, si trattano tutte le parti anatomiche del turbinato, incluso il tessuto osseo e si abolisce l’uso di tamponi nasali, elemento importante nel benessere e nella guarigione del paziente."

"This book describes in details an innovative surgical technique called modified inferior turbinoplasty, which offers an excellent solution to the problems associated with the lower turbinate hypertrophy. A turbinate (or nasal concha) is a long, narrow, curled bone shelf that protrudes into the breathing passage of the nose. Most surgical interventions treat only the soft parts of hypertrophic turbinates using laser therapy, radiofrequency treatment, and electrocoagulation, but these procedures often lead to relapse. With this technique, in contrast, all anatomic parts of the turbinate are treated, including bone tissue: the surgeon reduces the inferior nasal concha and the internal nasal tissue, and the mucosa is then remodeled with sutures. The modified inferior turbinoplasty allows the complete avoidance of swabs in the nose, which is fundamental for patients well-being and grant them a quicker recovery. "

"ABSTRAKPemanfaatan ganggang sebagai komoditi perdagangan atau bahan baku industri masih relatif kecil jika dibandingkan dengan keanekaragaman ganggang. Penelitian ini bertujuan untuk mengetahui efek Ganggang Coklat Turbinaria decurrens Bory pada jumlah tumor hewan model kanker kolon yang diinduksi AOM Azoksimetan dan DSS Dextran Sodium Sulfat . Penelitian ini dimulai dengan membagi hewan uji sebanyak 36 ekor dalam 6 kelompok, kelompok normal yang tidak diberi perlakuan, kelompok kontrol positif yang diberikan celekoksib, Kontrol negatif yang tanpa pemberian ekstrak, kelompok dosis 1 3.61 mg/20 g , dosis 2 7.22 mg/20 g dan dosis 3 14.4 mg/20 g . Setiap kelompok uji di induksi dengan Azoksimetan pada hari pertama dan ditunggu hingga seminggu, selanjutnya dilakukan induksi Dekstran Sodium Sulfat 2 dengan menggunakan sonde lambung selama 5 hari. Setelah induksi DSS yang pertama hewan lalu hanya diberikan induksi ekstrak selama 16 hari, selanjutnya dilakukan induksi DSS 2 selama 5 hari. Induksi ini diberikan pada semua hewan uji kecuali kelompok normal. Setelah DSS siklus 2 diberikan maka hewan diberikan ekstrak selama 16 hari. Pengukuran berat badan dilakukan setiap hari dan untuk hewan yang mati dicatat setiap harinya. Diakhir penelitian hewan disakrifasi dan dibedah usus besarnya kemudian dihitung jumlah rata-rata tumor yang ada. Hasil yang diperoleh yaitu ekstrak etanol 70 ganggang coklat Turbinaria decurrens Bory memiliki efek untuk menghambat pertumbuhan tumor pada hewan model kanker kolon yang diinduksi oleh AOM dan DSS dan memiliki kemampuan bertahan hidup yang lebih dari 50 yaitu sebesar 66.67 . Dosis yang dapat menghambat pertumbuhan tumor dengan baik adalah dosis 1 yaitu 3.61 mg/20 g.

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ABSTRACTUtilization of algae as a commodity trade or industrial raw materials is still relatively small when compared with the diversity of algae, whereas Indonesia is known as an archipelago country which two thirds of its territory is the sea and has the longest coastline in the world that is 81 thousand km. This study aims to determine the effect of Turbinaria decurrens Bory Chocolate Algae on the number of animal tumors modeled by AOM Azoxymethane colon cancer and DSS Dextran Sodium Sulfate . The study began by dividing the test animals by 36 in six groups, the untreated normal group, the positive control group given celecoxib, negative control without extract, dose group 1 3.61 mg 20 g , dose 2 7.22 mg 20 g and a dose of 3 14.4 mg 20 g . Each test group was induced with Azoxymethane on the first day and waited up to a week, then induction of 2 Sodium Sulfate Dextran by using gastric sonde for 5 days. After the first DSS induction the animals were then only given induced extract for 16 days, then 2 DSS induction was done for 5 days. This induction is given to all test animals except for the normal group. After DSS cycle 2 is given then the animal is given extract for 16 days. Weight measurements are taken daily and for dead animals are recorded daily. At the end of the study the animal is disacrified and the colon surgery is then calculated the average number of tumors present. The results obtained that the extract of ethanol 70 brown algae Turbinaria decurrens Bory has an effect to inhibit tumor growth in animal models of colon cancer induced by AOM and DSS and have survival ability more than 50 that is equal to 66.67 . The dose that can inhibit tumor growth well is the dose of 1 is 3.61 mg 20 g."

"ABSTRAKTesis ini membahas gambaran hasil terapi rinitis alergi persisten sedang-berat pada 2 kelompok terapi di RSCM, dimana kelompok pertama diberikan terapi reduksi konka radiofrekuensi disertai steroid topikal hidung, sedangkan kelompok kedua diberikan terapi steroid topikal hidung saja. Penelitian ini adalah penelitian pendahuluan dengan metode penelitian uji klinis. Penilaian skala analog visual (SAV) untuk 4 gejala utama rinitis alergi (bersin-bersin, gatal hidung, ingus encer, dan sumbatan hidung), pemeriksaan nasoendoskopi untuk menilai ukuran konka inferior, dan pemeriksaan aliran udara hidung dengan Peak Nasal Inspiratory Flow (PNIF) dilakukan pada sebelum terapi dan minggu ke-6 pasca terapi. Pada penelitian ini rerata usia kelompok steroid topikal hidung adalah 28,3 tahun (SD 10,3 tahun), sedangkan pada kelompok reduksi konka adalah 27,6 tahun (SD 8,1 tahun). Sebanyak 67% subyek adalah perempuan. Keluhan rinitis alergi paling berat adalah sumbatan hidung. Sebanyak 80% subyek penelitian mengalami hipertrofi konka inferior, yaitu 50% hipertrofi derajat 3 dan 30% hipertrofi derajat 4. Ditemukan perbedaan bermakna ukuran konka inferior sebelum terapi dengan minggu ke-6 pasca terapi, baik pada kelompok reduksi konka maupun kelompok steroid dan ditemukan pula perbedaan bermakna ukuran konka inferior pada minggu ke-6 pasca terapi antara kedua kelompok terapi. Untuk nilai SAV gatal hidung, ditemukan perbedaan bermakna sebelum terapi dengan minggu ke-6 pasca terapi, baik pada kelompok reduksi konka maupun kelompok steroid topikal saja, dan ditemukan pula perbedaan bermakna nilai SAV gatal hidung pada minggu ke-6 pasca terapi antara kedua kelompok terapi. Perbedaan bermakna sebelum terapi dengan minggu ke-6 pasca terapi ditemukan pada nilai SAV gejala rinitis alergi yang lain (bersin-bersin, ingus encer, dan sumbatan hidung) dan nilai PNIF, baik pada kelompok reduksi konka maupun kelompok steroid topikal saja. Tidak ditemukan perbedaan bermakna nilai SAV gejala rinitis alergi yang lain dan nilai PNIF, jika dibandingkan antara kedua kelompok terapi pada minggu ke-6 pasca terapi.

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ABSTRACTThis paper reported result of treatment in moderate-severe allergic rhinitis at Cipto Mangunkusumo Hospital. In this research, there were 2 groups of treatment. First group was treated with radiofrequency turbinoplasty and nasal steroid after turbinoplasty performed, second group was treated only with nasal steroid. This research is a pilot clinical study. Analogue Visual Scale for 4 major symptoms of allergic rhinitis (sneezing, nose itching, rhinorrhea, nose obstruction), nasoendoscopy to evaluate size of inferior turbinate, peak nasal inspiratory flow to evaluate nasal air flow were performed before treatment and 6 weeks after treatment. In this research, mean age of patients in steroid alone group was 28,3 years old with standard deviation 10,3 years, and in radiofrequency group mean age was 27,6 years old with standard deviation 8,1 years. Sixty seven percent patients was woman. The most bothering symptom found was nasal obstruction. Eighty percent patients had inferior turbinate hypertrophy, 50% patient with grade 3 and 30% patient with grade 4. Statistical significance in inferior turbinate degree was found if comparison performed before treatment with 6 weeks after treatment, in both treatment group,and also found statistical difference if compared between 2 treatment group at 6 weeks after treatment. Statistical difference was found only in VAS for nasal itching symptom if compared between 2 treatment group at 6 weeks after treatment. There were no statistical difference for another major symptom with VAS if compared between 2 group at 6 weeks after treatment. If comparison was performed before treatment with 6 weeks after treatment for VAS in all allergic rhinitis major symptoms and peak nasal inspiratory flow, there were statistical significance found, in radiofrequency group and nasal steroid group, but if comparison was performed between 2 treatment groups at 6 weeks after treatment, there were no statistical difference found."

"Madible fracture, also known as fractures of jaws are breaks through the mandiblebone. Fractures of mandible account for 36 -70% of all maxillofacial injuries (1,2,3)the symphysis and parasymphysis account for 17%of mandible fracture (4) 75 % to85 % of mandible fracture occurs in males with majority occuring in their twenties &thirties (5,6,7). 43% of the patients had an associated injury. Of these patients, headinjuries occurred in 39% of patients, head and neck lacerations in 30%, midfacefractures in 28%, ocular injuries in 16%, nasal fractures in 12%, and cervical spinefractures in 11% - 53% of patients had unilateral fractures, 37% of the patients had2 fractures, and 9% had 3 or more fractures."

"Midfacial rejuvenation is a comprehensive review of the majority of procedures and options for midfacial aesthetic and corrective surgery. Each contributor offers a unique approach to the midfacial area, with detailed specifics for every technique. Chapters on midfacial anatomy, complications and their management complete the comprehensive coverage of the subject matter, resulting in a reference text that will benefit every practitioner dealing with the midfacial region. Features, one of the first books to focus exclusively on the midfacial area, highly illustrated and with clear, step-by-step instructions on performing a variety of midface lifts, implants, sutures, grafts, and fillers, over 300 full color images, includes in-depth chapters on midfacial anatomy and the anatomic basis of aging, multiple approaches to midfacial rejuvenation by well-known surgeons in fields such as oculoplastics, facial plastics, general plastics, and dermatologists."

"With the time available to surgeons-in-training ever dwindling, there is great emphasis placed on practical learning tools. Mirroring his earlier book on practical procedures in trauma surgery, Prof Giannoudis has produced a reference in more elective techniques. In most medical schools, most emphasis is placed on orthopaedic trauma surgery, with elective techniques often delayed until much later in a surgeon?s training."

"This highly illustrated text book will be an essential guide for surgeons in training, providing step by step approaches to performing Joint Aspiration/Injection, Bone Graft Harvesting and Lower Limb Amputations. Practical guidance will be given on Indications- Preoperative assessment, positioning and preparing the patient, approach required, tips and tricks, closure, postoperative complications, protocol of mobilization and follow-up procedure. All the procedures performed will include numerous intraoperative photographs and illustrations."