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"For practitioners at all stages of experience, diseases of the parathyroid glands are not easily deciphered. There are many subtleties to its pathology and diagnosis. Today, the wealth of new information from molecular medicine makes it very challenging for the individual practitioner to have a complete picture of these entities. Diseases of the parathyroid glands addresses these issues by offering a concise, user-friendly text that provides state-of-the-art background on mineral physiology and its regulation and couples this to a variety of clinical topics of parathyroid gland pathology. Introductory chapters cover calcium regulation and parathyroid gland physiology, drawing upon many of the new aspects of glandular control mechanisms beyond the classical ones associated with calcium alone. The majority of the text covers clinical problems. Although most chapters address problems in adult medicine, three separate chapters are devoted to pediatric problems of hyper- and hypoparathyroidsm and parathormone resistance states. In addition, there are several chapters on less common but equally challenging problems such as parathyroid cancer, calciphylaxis, cystic lesions of the glands, and ectopic glandular disease. The final chapters detail the techniques of parathyroid gland imaging and surgical treatment. "

"This highly illustrated book, complete with comprehensive clinical references and annotated images, will serve as a leading text to educate head and neck surgeons, endocrinologists, and radiologists on the basics and nuances of thyroid and parathyroid ultrasound. It emphasizes the use of ultrasound as an office-based modality by clinicians and radiologists who actively care for this special set of patients. This text uniquely combines the collaboration between a clinician/surgeon and radiologist who share their extensive experience in head and neck ultrasound."

"This book is a unique in-depth and comprehensive reference that covers all surgically relevant thyroid and parathyroid diseases and presents the latest information on their management. International authorities discuss operative techniques and treatments in detail and explain the rationales for their favored approaches. The topics of this second edition include the description of surgically relevant pathologies, preoperative surgical evaluation, decision making, and operative strategies for the various thyroid and parathyroid diseases. In addition, experts present the molecular basis for thyroid neoplasia, review the current understanding of the genetics of inherited thyroid and parathyroid diseases, and discuss the management of recurrent and locally invasive thyroid cancer. Evolving modern operative techniques such as neuromonitoring and minimally invasive (videoscopic) approaches to the thyroid and parathyroids are also covered."

"The Handbook on parathyroid diseases presents a comprehensive and concise overview of our current knowledge in the area of parathyroid function, hormone regulation and disease states. The handbook educates the reader using a case-based approach presenting current evidence in the field. The material is presented in an easy to read and understandable language and uses a plethora of tables and text boxes where possible. Complex concepts are conveyed in simple and clear language. Leading international experts contribute to this state of the art book providing a true depth of knowledge and practicality."

"Karsinoma paratiroid merupakan neoplasma yang jarang ditemukan, dengan frekuensi kurang dari 1% dari seluruh kasus hiperparatiroidisme primer. Beberapa gambaran klinis dan biokimiawi dapat mengarahkan pada karsinoma paratiroid namun diagnosis pre dan intraoperatif yang akurat masih sulit ditegakkan. Studi ini melaporkan satu kasus karsinoma paratiroid yang terdiagnosis pasca-operasi. Intraoperatif ditemukan pembesaran kelenjar paratiroid yang telah menginfiltrasi laringeus rekuren dan kelenjar tiroid kanan. Hasil histopatologik menunjukkan nodul tumor yang dipisahkan oleh jaringan ikat tebal, disertai invasi pada kapsul dan jaringan sekitar. Diagnosis akhir karsinoma paratiroid ditegakkan berdasarkan gambaran klinis dan pemeriksaan spesimen

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AbstractKarsinoma paratiroid merupakan neoplasma yang jarang ditemukan, dengan frekuensi kurang dari 1% dari seluruh kasus hiperparatiroidisme primer. Beberapa gambaran klinis dan biokimiawi dapat mengarahkan pada karsinoma paratiroid namun diagnosis pre dan intraoperatif yang akurat masih sulit ditegakkan. Studi ini melaporkan satu kasus karsinoma paratiroid yang terdiagnosis pasca-operasi. Intraoperatif ditemukan pembesaran kelenjar paratiroid yang telah menginfiltrasi laringeus rekuren dan kelenjar tiroid kanan. Hasil histopatologik menunjukkan nodul tumor yang dipisahkan oleh jaringan ikat tebal, disertai invasi pada kapsul dan jaringan sekitar. Diagnosis akhir karsinoma paratiroid ditegakkan berdasarkan gambaran klinis dan pemeriksaan spesimen"

"Latar belakang: Sitologi aspirasi jarum halus merupakan metode yang efektif dan aman dalam menilai lesi kelenjar liur. Gambaran morfologi yang bervariasi serta sitomorfologik yang saling tumpang tindih, mengakibatkan sulitnya dalam mendiagnosis lesi kelenjar liur. Penelitian ini bertujuan untuk mengetahui akurasi diagnostik dan menganalisa gambaran sitomorfologik aspirasi lesi kelenjar liur.Metode: Dilakukan penelusuran sediaan sitologik lesi kelenjar liur tahun 2005-2009 pada arsip Departemen Patologi Anatomik FKUI/RSCM. Didapatkan 107 kasus sitologi lesi kelenjar liur, dan dilakukan pemeriksaan ulang. Terdapat 7 kasus dieksklusi karena sediaan tidak layak baca. Dilakukan pula penelusuran sediaan histopatologiknya dan dikorelasikan dengan sediaan sitologik. Uji diagnostik diaplikasikan pada 39 kasus berpasangan sitologi-histopatologik.Hasil: Kasus lesi kelenjar liur dari tahun 2005-2009 berjumlah 100 kasus, diantaranya 27 kasus negatif, delapan kasus inkonklusif dan 65 kasus lesi neoplastik. Pada 39 kasus berpasangan, empat belas kasus diantaranya memiliki diagnosis berbeda, dengan 3 kasus negatif palsu, satu kasus positif palsu. Secara keseluruhan dalam membedakan lesi malignant atau non-malignant didapatkan sensitivitas 82,35%, spesifisitas 95,45%, NPV 87,5% dan PPV 93,34%.Kesimpulan: Penelitian ini menunjukkan bahwa akurasi diagnostik sitologi lesi kelenjar liur sangat bervariasi, dengan sensitivitas 82,35% dan spesifisitas 95,45% dalam membedakan lesi malignant atau non-malignant; sekalipun tidak dapat menegakkan diagnosis definitif, namun tetap dapat membantu klinisi dalam tata laksana kasus.

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AbstractBackground: Fine-needle aspiration (FNA) is an effective and safe procedure for analyzing salivary gland lesions. Various morphological and overlapping cytomorphology features can bring difficulty in diagnosis of the salivary gland lesions. This study aimed to evaluate the diagnostic accuracy of fine needle aspiration cytology of salivary glands lesions.Methods: There were 107 cases of cytology and 39 cases of histopathology of salivary gland lesions collected and reviewed from the archives of Anatomical Pathology Department, Faculty of Medicine, Universitas Indonesia / Cipto Mangunkusumo Hospital from 2005-2009. Seven cases of cytology were excluded, due to unsatisfactory specimens. Diagnostic test was applied to analyze the 39 pairs of cytology-histopathology cases.Results: There were 100 cases of salivary gland lesions cytology obtained, consisted of 27 negatives, eight cases inconclusive and 65 cases of neoplastic lesions. Of the 39 pair cases, fourteen cases showed result discrepancies between cytology and histopathology, with 3 false-negative cases and 1 false-positive case. The sensitivity and specificity of cytology analysis in differentiating malignant from non-malignant lesions were 82.35%, and 95.45% respectively, NPV 87.5% and PPV 93.34%.Conclusion: This study showed diagnostic accuracy of FNA cytology salivary gland lesions was varied, with 82.35% sensitivity and 95.45% specificity in differentiating malignant from non-malignant hence this information can still be used for case management."