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"[ABSTRAKGangguan depresi mayor merupakan suatu gangguan kejiwaan ditandai dengankemurungan, ketiadaan gairah hidup, perasaan tidak berguna dan putus asa danmengalami minimal empat dari gejala berikut yaitu perubahan berat badan dannafsu makan, perubahan tidur dan aktivitas, tidak ada energi, rasa bersalah,masalah dalam berfikir dan membuat keputusan, berfikir berulang tentangkematian dan bunuh diri tampa riwayat episode manik, campuran atau hipomanik,sekurang-kurangnya telah dirasakan selama 2 minggu. Survei kesehatan mentaldunia pada 17 negara menemukan sekitar 1 dari 20 orang dilaporkan menderitaepisode depresi setiap tahunnya, paling sering terjadi adalah gangguan depresimayor. Pengobatan dengan farmakoterapi golongan antidepresan hanyamenunjukkan efektifitas 60-70% disertai efek samping yang serius sehinggaberbagai modalitas terapi dikembangkan, salah satunya akupunktur. Penelitian inibertujuan untuk mengetahui efektivitas terapi kombinasi akupunktur denganantidepresan dibandingkan kombinasi akupunktur sham dengan antidepresanterhadap perubahan skor Hamilton Rating Scale for Depression (HAM-D 17)pada penderita gangguan depresi mayor. Uji klinis acak tersamar tunggaldilakukan pada 48 pasien gangguan depresi mayor dialokasikan ke dalamkelompok kombinasi akupunktur dengan antidepresan dan kelompok kombinasiakupunktur sham dengan antidepresan. Penilaian kemajuan terapi digunakan skorHAM-D 17. Hasil penelitian menunjukkan rerata skor HAM-D 17 pada kelompokkasus sebelum terapi 22,2±3,38 dan setelah terapi ke-12 turun menjadi 7,3±2,64.Sedangkan pada kelompok kontrol rerata skor HAM-D 17 sebelum terapi21,4±3,10 dan setelah terapi ke-12 turun menjadi 9,3±3,33. Terdapat perbedaanbermakna antara selisih rerata penurunan skor HAM-D 17 sebelum dan setelah 12kali terapi pada kelompok kasus 14,9±2,45 dibandingan dengan kelompok kontrol12,2±4,30 (p<0,005). Terapi kombinasi akupunktur dengan antidepresan lebihefektif mengurangi gejala gangguan depresi mayor dibandingkan kombinasiakupunktur sham dengan antidepresan.

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ABSTRACTMajor depressive disorder is a psychiatric disorder that is characterized at leastfour of the following symptoms, loss of weight and appetite, sleep disturbance andloss of interest of activity, low energy level, guilt, difficulty concentrating andmaking decisions, recurrent death or suicide, without a history of manicepisodes, mixed or hypomanic. These sings and symptoms have been felt at leastfor 2 weeks. The mental health survey conducted in 17 countries found that about1 in 20 people are reported to suffer from a depressive episode each year andmost are major depressive disorder. The effectiveness of antidepressantmedication only 60-70% with serious side effects, so that various therapeuticmodalities developed, one of which is acupuncture. This study aims to determinethe effectiveness of combination therapy of acupuncture with antidepressantscompared to combination of sham acupuncture with antidepressants in patientswith major depressive disorder and the outcome was the score Hamilton RatingScale for Depression (HAM-D 17). Single-blind randomized clinical trialconducted in 48 patients with major depressive disorder and the patients wereallocated into two groups, intervention (acupuncture with antidepressants) andcontrol (sham acupuncture with antidepressant). The mean of HAM-D 17 score inthe intervention group before treatment was 22,2±3,38 and after treatment was7,3±2,64. The mean of HAM-D 17 score in control group before treatment was21,4±3,10 and after treatment was 9,3±3,33. There was significant differencesbetween intervention and control group before and after 12 times of therapy in themean decrease of score on HAM-D 1714.9±2.45 to12.2±4.30 (p<0.005). Acombination of acupuncture therapy with antidepressants is more effective inreducing the symptoms of major depressive disorder compared to shamacupuncture combination with antidepressants, Major depressive disorder is a psychiatric disorder that is characterized at leastfour of the following symptoms, loss of weight and appetite, sleep disturbance andloss of interest of activity, low energy level, guilt, difficulty concentrating andmaking decisions, recurrent death or suicide, without a history of manicepisodes, mixed or hypomanic. These sings and symptoms have been felt at leastfor 2 weeks. The mental health survey conducted in 17 countries found that about1 in 20 people are reported to suffer from a depressive episode each year andmost are major depressive disorder. The effectiveness of antidepressantmedication only 60-70% with serious side effects, so that various therapeuticmodalities developed, one of which is acupuncture. This study aims to determinethe effectiveness of combination therapy of acupuncture with antidepressantscompared to combination of sham acupuncture with antidepressants in patientswith major depressive disorder and the outcome was the score Hamilton RatingScale for Depression (HAM-D 17). Single-blind randomized clinical trialconducted in 48 patients with major depressive disorder and the patients wereallocated into two groups, intervention (acupuncture with antidepressants) andcontrol (sham acupuncture with antidepressant). The mean of HAM-D 17 score inthe intervention group before treatment was 22,2±3,38 and after treatment was7,3±2,64. The mean of HAM-D 17 score in control group before treatment was21,4±3,10 and after treatment was 9,3±3,33. There was significant differencesbetween intervention and control group before and after 12 times of therapy in themean decrease of score on HAM-D 1714.9±2.45 to12.2±4.30 (p<0.005). Acombination of acupuncture therapy with antidepressants is more effective inreducing the symptoms of major depressive disorder compared to shamacupuncture combination with antidepressants]"

"ABSTRAKDepresi merupakan suatu gangguan kejiwaan pada alam perasaan, yang ditandai dengan kesedihan, hilangnya minat atau kebahagiaan, perasaan bersalah, gangguan tidur dan nafsu makan, perasaan lelah dan konsentrasi yang kurang baik. Tiga terapi utama untuk depresi yaitu psikoterapi, farmakoterapi dan electroconvulsive therapy (ECT). Selective Serotonin Re-uptake Inhibitor (SSRI) merupakan terapi antidepresan yang paling sering dipakai. Efektifitas farmakologis antidepresan hanya mencapai 60%-70%. Sebagian pasien depresi tidak merespons penuh, mengalami relaps, atau menderita efek samping yang tidak diharapkan sehingga memerlukan pengembangan terapi pilihan lain, seperti laserpunktur.Penelitian ini bertujuan untuk mengetahui efektivitas terapi kombinasi laserpunktur dengan antidepresan dan psikoterapi dibandingkan dengan terapi kombinasi laserpunktur sham dengan antidepresan dan psikoterapi terhadap perubahan skor Hamilton Rating Scale for Depression 17 (HAM-D 17) dan kadar serotonin penderita depresi. Uji klinis acak tersamar tunggal pada 33 penderita depresi dialokasikan kedalam kelompok perlakuan dan kontrol. Terdapat penurunan skor HAM-D 17 yang bermakna (p<0.001) setelah 8 kali terapi laserpunktur dan peningkatan kadar serotonin yang bermakna (p=0,004) setelah terapi.Penelitian ini menunjukkan terapi kombinasi laserpunktur dengan antidepresan dan psikoterapi efektif mengurangi gejala depresi dan meningkatkan kadar serotonin lebik baik dibandingkan terapi kombinasi laserpunktur sham dengan antidepresan dan psikoterapi saja.

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ABSTRACT

Depression is a psychiatric disorder in mood, which is characterized by sadness, loss of interest or happiness, feeling guilty or worthless, sleep or appetite disorders, feeling tired and lack of concentration. There are three main treatment for depression are psychotherapy, pharmacotherapy and electroconvulsive therapy (ECT). The effectiveness of pharmacological antidepressant only reach 60% to 70%. The majority of depressed patients do not respond fully, relapse, or suffer side effects are not expected to require the development of therapies other options, one of which laserpuncture.

This study aims to determine the effectiveness of combination therapy with antidepressants and psychotherapy laserpuncture compared with sham laserpuncture combination therapy with antidepressants and psychotherapy to change in Hamilton Rating Scale for Depression 17 (HAM-D 17) and the serotonin levels of people with depression. Single-blind randomized clinical trial was conducted on 33 patients with depression were allocated into intervention and control groups.

The results showed there is a decrease in HAM-D 17 were significantly (p <0.001). There is a significant increase serotonin levels (p = 0.004). Conclusion of the study is laserpuncture combination therapy with antidepressants and psychotherapy are effective in reducing symptoms of depression and elevating cortisol level compared to sham laserpuncture combination therapy with antidepressants and psychotherapy."

"Hingga saat ini masalah depresi masih tetap merupakan topik yang menarik dan hangat. Hal ini disebabkan karena masalahnya yang besar dan kompleks; meliputi antara lain gambaran klinis, klasifikasi diagnosis, distribusi kasus dan penanganannya.Penelitian yang dilakukan di Eropa dan Amerika menunjukkan sekitar 8-11 % pria dan 18-23 % wanita akan mengalami episode depresi disuatu saat dalam perjalanan hidupnya (5,22). WHO (World Health Organi zation) memperkirakan depresi dialami oleh 3 % penduduk dunia - 100.000.000 jiwa - dan menurut Sartorius (1979), dari tahun ke tahun angka tersebut akan terus meningkat (12,16).Khusus di Indonesia, penderita depresi secara klinis diperkirakan minimal 3.000.000 jiwa (Kusumanto S., Iskandar Y., 1985). Namun bila ditinjau menurut data yang ada, baik di Rumah Sakit Umum maupun Rumah Sakit Jiwa, ternyata angka depresi sangat kecil. Hal ini mungkin disebabkan karena masih banyak pasien, atau bahkan para dokter yang tidak mengenal dan menyangkal bahwa seseorang menderita depresi (15). Dalam pada itu data menunjukkan bahwa dari seluruh pasien yang berkunjung ke dokter, 10 % diantaranya terdiri dari pasien depresi dan separuhnya merupakan depresi dalam bentuk tersamar (12,18,21)."

"[ABSTRAKUremik pruritus masih menjadi masalah dan mengurangi kualitas hidup pada pasien hemodialisis, meskipun telah banyak kemajuan dalam teknik dialisis, serta terapi yang ada belum memberikan hasil yang maksimal. Terapi akupunktur dapat dikembangkan sebagai terapi pendamping pada terapi hemodialisis untuk mengurangi gejala uremik pruritus. Penelitiasn ini merupakan penelitian akupunktur pertama di Indonesia dengan subyek pasien hemodialisis. Tiga puluh tujuh pasien hemodialisis dengan uremik pruritus dibagi dalam dua kelompok secara acak, kelompok akupunktur (n=18) mendapat terapi akupunktur pada titik tunggal LI11 Quchi, sementara kelompok kontrol (n=19) mengunakan jarum plasebo The Park Sham Device. Terapi akupunktur dilakukan saat hemodialisis, seminggu dua kali sebanyak 12 kali. Skor pruritus dinilai menggunakan kuesioner pruritus 5D sebelum terapi, setelah terapi ke-4, ke-8 dan setelah terapi ke-12, serta penilaian lanjutan 4 dan 8 minggu setelah terapi selesai. Perbedaan bermakna skor pruritus 5D antara kelompok akupunktur dan kelompok kontrol terjadi setelah akhir terapi akupunktur (7,89±0,832 vs 10,63±3,166; p=0,003) dan penilaian lanjutan 4 minggu setelah terapi selesai(8,06±1,830 vs 10,95±3,341; p=0,001). Terapi akupunktur efektif menurunkan skor uremik pruritus pada pasien hemodialisis yang menjalani dialisis seminggu dua kali.

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ABSTRACTUremic pruritus still gives problems for hemodialysis patients especially to reducing their quality of life, although it has been many advancements in dialysis techniques, recent therapies not yet provide optimum results. Acupuncture has a role as a complement in hemodialysis therapy to alleviate the symptoms of uremic pruritus in hemodialysis patients. This study is the first acupuncture research in Indonesia with the subject of hemodialysis patients. Thirty-seven hemodialysis patients with uremic pruritus were divided randomly into two groups, the acupuncture group (n = 18) received acupuncture treatment at a single point LI11 Quchi, while the control group (n = 19) using a placebo needle The Park Sham Device. Acupuncture treatment was done simultaneously with hemodialysis therapy, twice a week for 12 times. The pruritus scores was assessed using a 5D pruritus questionnaire before treatment, after 4th, 8th, 12th acupuncture treatment and at 4 and 8 weeks follow up. Significant differences 5D pruritus scores between the acupuncture group and the control group occurred after the end of acupuncture treatment (7.89±0.832 vs 10.63±3.166; p = 0.003) and at 4 weeks follow up (8.06±1.830 vs. 10.95±3.341; p = 0.001). Acupuncture treatment is effective in lowering the score of uremic pruritus in hemodialysis patients who undergo dialysis twice a week.;Uremic pruritus still gives problems for hemodialysis patients especially to reducing their quality of life, although it has been many advancements in dialysis techniques, recent therapies not yet provide optimum results. Acupuncture has a role as a complement in hemodialysis therapy to alleviate the symptoms of uremic pruritus in hemodialysis patients. This study is the first acupuncture research in Indonesia with the subject of hemodialysis patients. Thirty-seven hemodialysis patients with uremic pruritus were divided randomly into two groups, the acupuncture group (n = 18) received acupuncture treatment at a single point LI11 Quchi, while the control group (n = 19) using a placebo needle The Park Sham Device. Acupuncture treatment was done simultaneously with hemodialysis therapy, twice a week for 12 times. The pruritus scores was assessed using a 5D pruritus questionnaire before treatment, after 4th, 8th, 12th acupuncture treatment and at 4 and 8 weeks follow up. Significant differences 5D pruritus scores between the acupuncture group and the control group occurred after the end of acupuncture treatment (7.89±0.832 vs 10.63±3.166; p = 0.003) and at 4 weeks follow up (8.06±1.830 vs. 10.95±3.341; p = 0.001). Acupuncture treatment is effective in lowering the score of uremic pruritus in hemodialysis patients who undergo dialysis twice a week., Uremic pruritus still gives problems for hemodialysis patients especially to reducing their quality of life, although it has been many advancements in dialysis techniques, recent therapies not yet provide optimum results. Acupuncture has a role as a complement in hemodialysis therapy to alleviate the symptoms of uremic pruritus in hemodialysis patients. This study is the first acupuncture research in Indonesia with the subject of hemodialysis patients. Thirty-seven hemodialysis patients with uremic pruritus were divided randomly into two groups, the acupuncture group (n = 18) received acupuncture treatment at a single point LI11 Quchi, while the control group (n = 19) using a placebo needle The Park Sham Device. Acupuncture treatment was done simultaneously with hemodialysis therapy, twice a week for 12 times. The pruritus scores was assessed using a 5D pruritus questionnaire before treatment, after 4th, 8th, 12th acupuncture treatment and at 4 and 8 weeks follow up. Significant differences 5D pruritus scores between the acupuncture group and the control group occurred after the end of acupuncture treatment (7.89±0.832 vs 10.63±3.166; p = 0.003) and at 4 weeks follow up (8.06±1.830 vs. 10.95±3.341; p = 0.001). Acupuncture treatment is effective in lowering the score of uremic pruritus in hemodialysis patients who undergo dialysis twice a week.]"

"ABSTRAK Detrusor underactivity DU adalah berkurangnya kekuatan dan/atau durasi kontraksi yang mengakibatkan pengosongan kandung kemih yang memanjang atau inkomplit. Sebanyak enam pasien dengan diagnosis DU diinklusikan dalam penelitian ini. Akupunktur tanam benang dilakukan dengan menggunakan polydioxanone PDO yang ditusukkan di titik akupunktur BL33 dan CV3 dengan teknik penetrating needling. Akupunktur tanam benang dilakukan sebanyak satu kali. Transcutaneous tibial nerve stimulation TTNS dilakukan sebanyak 3 kali seminggu selama 4 minggu. Hasilnya penelitian menunjukkan tidak terdapat perbedaan bermakna antara rerata volume berkemih sebelum 72,00 70,48 dan setelah 158,17 139,58 akupunktur tanam benang dan TTNS, p = 0,115, namun didapatkan peningkatan dengan rerata 86,17 110,80. Tidak terdapat perbedaan bermakna antara nilai PVR sebelum 164,00 173,69 dan setelah 74,83 126,28 terapi, p = 0,151, namun didapatkan penurunan sebesar 89,17 129,07. Tidak terdapat perbedaan bermakna antara rerata Qmax sebelum 4,12 3,28 dan setelah 12,35 9,20 , p = 0,085, namun didapatkan peningkatan sebesar 8,23 9,41. Terdapat perbedaan bermakna antara skor kualitas hidup sebelum dan setelah terapi dengan p = 0,017. Kesimpulan : akupunktur tanam benang dan TTNS dapat meningkatkan volume berkemih, menurunkan PVR, dan meningkatkan Qmax penderita DU, dan dapat memperbaiki kualitas hidup penderita DU secara signifikan. ABSTRACT Detrusor underactivity DU is a contraction of reduced strength and/or duration resulting in prolonged and/or incomplete bladder emptying. A total of six DU patients were included in this research. We did thread-embedding acupuncture by inserting polydioxanone PDO into BL33 and CV3 acupuncture points with penetrating needling techniques. Thread-embedding acupuncture was given once. Transcutaneous tibial nerve stimulation TTNS was given 3 times in a week during 4 weeks. The results showed no significant differences between before and after treatment on voided volume 72,00 70,48 and 158,17 139,58 , p = 0,115, but there was improvement with mean 86,17 110,80. There was no significant difference between before and after treatment on PVR 164,00 173,69 and 74,83 126,28 , p = 0,151, but there was improvement with mean 89,17 129,07. There was no significant difference between before and after treatment on Qmax 4,12 3,28 and 12,35 9,20 , p = 0,085, but there was improvement with mean 8,23 9,41. There was significant difference between before and after treatment on quality of life scoring with p = 0,017. Conclusion : thread embedding acupuncture and TTNS increase voided volume, and Qmax, decrease PVR, improve quality of life in in detrusor underactivity patients significantly "

"Penyakit Paru Obstruktif Kronik (PPOK) kini telah menjadi penyebab kematian terbanyak keempat di dunia. Masih tingginya angka mortalitas pada tatalaksana PPOK mengharuskan pengembangan modalitas terapi yang terus-menerus. Penelitian ini bertujuan untuk mengetahui pengaruh terapi kombinasi akupunktur tanam benang dan medikamentosa terhadap indeks BODE pasien PPOK. Uji klinis acak tersamar ganda dengan pembanding dilakukan terhadap 48 pasien yang dialokasikan ke dalam kelompok kasus (kombinasi akupunktur tanam benang dan medikamentosa) atau kelompok kontrol (kelompok akupunktur sham dan medikamentosa). Akupunktur tanam benang dilakukan pada titik BL13 Feishu, BL43 Gaohuangshu, BL20 Pishu, BL23 Shenshu dan ST40 Fenglong sebanyak 2 kali dengan interval 15 hari. Indeks BODE sebagai keluaran primer dinilai pada hari ke-1 dan hari ke-30. Hasil penelitian menunjukkan perbedaan yang bermakna secara statistik maupun klinis antar kedua kelompok. Rerata penurunan indeks BODE 1,83 lebih rendah pada kelompok kasus dibandingkan dengan kelompok kontrol (p =0,000). Disimpulkan bahwa terapi kombinasi akupunktur tanam benang dan medikamentosa lebih efektif menurunkan Indeks BODE dibandingkan dengan medikamentosa saja.

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Chronic Obstructive Pulmonary Disease (COPD) is now becoming the fourth leading cause of death in the world. Since high level of mortality following COPD medication, continous research to improve treatment modalities keeps on progressing. This study aimed to establish the effect of acupoint-catgut embedment combined with medical treatment on BODE index of COPD patient. A double blind randomized controlled trial has been conducted on 48 patient allocated into acupoint-catgut embedment with medication group (case group) or sham acupuncture with medication group (control group). Acupoint-catgut embedment was done on BL13 Feishu, BL43 Gaohuangshu, BL20 Pishu, BL23 Shenshu and ST40 Fenglong, 2 times with interval 15 days. BODE index as primary outcome was assessed on day-1 and day-30. The result shown statistically and clinically important difference between groups. BODE index was reduced 1,83 point lower in case group (p = 0,000). By that result, acupoint-catgut embedment combined with medical treatment is concluded more effective than medical treatment solely in reducing BODE index."

"Luka bakar didefinisikan sebagai kerusakan jaringan yang terjadi akibat aksi panas baik secara langsung maupun tidak langsung. Meskipun telah banyak kemajuan yang dibuat dalam terapi luka bakar, namun penyembuhan luka yang lambat masih menjadi tantangan dalam perawatan luka bakar. Akupunktur manual dapat mempercepat penyembuhan luka bakar melalui efek anti-inflamasi, meningkatkan re-epitelisasi dan angiogenesis. Sedangkan laser akupunktur merupakan terapi yang menggunakan laser enersi rendah untuk merangsang titik akupunktur. Penelitian ini menilai pengaruh akupunktur manual dan laser akupunktur terhadap kecepatan penyembuhan luka bakar yang diamati secara makroskopik dan mikroskopik. Tiga puluh enam tikus Wistar jantan dibagi secara acak kedalam kelompok kontrol (n=12), kelompok akupunktur manual (n=12), dan kelompok laser akupunktur (n=12). Setelah dilakukan induksi luka bakar, pengukuran luka dan perlakuan diberikan setiap dua hari sekali selama 14 hari. Separuh jumlah dari setiap kelompok diterminasi pada hari ke-7 dan separuh sisanya diterminasi pada hari ke-14 untuk dilakukan pengamatan mikroskopik. Pada pengukuran penutupan luas luka hari ke-14, didapatkan perbedaan bermakna (p=0,009) antara kelompok akupunktur manual (66,96 ± 9,17) dibandingkan kelompok kontrol (49,93 ± 9,15), dan perbedaan yang bermakna (p=0,009) antara kelompok laser akupunktur (72,48 ± 14,62) dibandingkan kelompok kontrol. Namun tidak didapatkan perbedaan bermakna (p=0,451) antara kelompok akupunktur manual dan laser akupunktur. Pada penilaian skoring mikroskopik hari ke-14 didapatkan perbedaan yang bermakna (p<0,001) antara kelompok akupunktur manual (16,17 ± 1,17) dibandingkan kelompok kontrol (10,33 ± 1,21), dan perbedaan yang bermakna (p=0,004) antara kelompok laser akupunktur (17,83 ± 1,47) dibandingkan kelompok kontrol. Namun tidak didapatkan perbedaan bermakna (p=0,058) antara kelompok akupunktur manual dan laser akupunktur. Hasil penelitian menunjukkan bahwa baik terapi akupunktur manual ataupun laser akupunktur dapat digunakan sebagai terapi tambahan untuk mempercepat penyembuhan luka bakar.

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Burns are defined as tissue damage that occurs as a result of the direct or indirect action of heat. Although many advanced treatments have been made in burn therapy, slow wound healing remains a challenge in burn treatment. Acupuncture can accelerate burn healing through its anti-inflammatory effect, increasing re-epithelialization and angiogenesis. While laser acupuncture is a therapy that uses low energy lasers to stimulate acupuncture points. This study assessed the effect of manual acupuncture and laser acupuncture on the speed of wound healing which were observed macroscopically and microscopically. Thirty-six male Wistar rats were randomly divided into control group (n=12), acupuncture group (n=12), and laser acupuncture group (n=12). After burn induction, wound measurements and treatments were given every two days for 14 days. Half of the numbers from each group were terminated on the 7th day and the remaining half were terminated on the 14th day for microscopic observation. On the 14th day of measurement of wound closure, there was a significant difference (p=0.009) between the acupuncture group (66.96 ± 9.17) compared to the control group (49.93 ± 9.15), and a significant difference (p =0.009) between laser acupuncture group (72.48 ± 14.62) compared to control group. However, there was no significant difference (p=0.451) between acupuncture and laser acupuncture groups. On the 14th day of microscopic scoring, there was a significant difference (p<0.001) between the acupuncture group (16.17 ± 1.17) compared to the control group (10.33 ± 1.21), and a significant difference (p = 0.004) between the laser acupuncture group (17.83 ± 1.47) versus the control group. However, there was no significant difference (p=0.058) between acupuncture and laser acupuncture groups. The results showed that either acupuncture therapy or laser acupuncture could be used as an adjunct therapy to accelerate burn healing."

"Fisik yang tidak aktif menempati peringkat keempat dalam daftar faktor risiko kematian. Bukti ilmiah semakin banyak mendukung bahwa dengan menjadikan latihan fisik sebagai bagian dari gaya hidup, dapat menurunkan risiko terjadinya berbagai penyakit. Namun, kelelahan otot dan nyeri otot juga banyak dirasakan oleh orang tidak terlatih yang baru memulai latihan. Penumpukan asam laktat di dalam otot sering dihubungkan dengan terjadinya kelelahan otot dan nyeri otot ini, yang akan memengaruhi kenyamanan melakukan latihan fisik. Saat ini, belum ada obat – obatan ataupun intervensi yang direkomendasikan secara resmi untuk menunda munculnya kelelahan otot atau nyeri otot. Penelitian ini menilai pengaruh akupunktur manual terhadap kenyamanan melakukan latihan fisik yang dievaluasi dengan menilai rerata kadar asam laktat, denyut nadi, tekanan darah sistolik dan diastolik, skala Borg untuk menilai tingkat kelelahan, serta Visual Analogue Scale (VAS) untuk menilai nyeri otot. Dua puluh enam pasien dibagi secara acak menjadi dua, kelompok akupunktur manual (n=13) dan akupunktur sham (n=13). Kedua kelompok menerima seri akupunktur yang sama, sebanyak 12 sesi dengan jarak 1 – 3 hari. Kedua kelompok juga melakukan latihan fisik yang sama, yaitu treadmill dengan intensitas sedang selama sepuluh menit, sebelum dan setelah seri terapi akupunktur. Penilaian rerata kadar asam laktat, denyut nadi, tekanan darah, skala Borg, dan VAS dilakukan dua kali, yaitu setelah latihan fisik sebelum memulai terapi pertama dan setelah latihan fisik setelah terapi terakhir. Hasil menunjukkan terdapat perbedaan bermakna pada rerata kadar asam laktat, denyut nadi, tekanan darah sistolik, tekanan darah diastolik, skala Borg, dan VAS pada kelompok akupunktur manual dibandingkan akupunktur sham. Rerata kadar asam laktat setelah terapi akupunktur 12 kali (p = 0,041). Rerata denyut nadi setelah terapi akupunktur 12 kali (p = 0,042). Rerata tekanan darah sistolik setelah terapi akupunktur 12 kali  (p = 0,024). Rerata tekanan darah diastolik setelah terapi akupunktur 12 kali (p = 0,035). Skala Borg setelah terapi akupunktur 12 kali (p = 0,043). VAS setelah terapi akupunktur 12 kali (p = 0,049). Penemuan ini menunjukkan bahwa terapi akupunktur manual memberikan pengaruh yang lebih baik terhadap kenyamanan melakukan latihan fisik.

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Physical inactivity ranks fourth in the list of risk factors for death. Scientific evidence increasingly supports that by making physical exercise a part of lifestyle, it can reduce the risk of various diseases. However, muscle fatigue and muscle aches are also felt by many untrained people who are just starting training. The buildup of lactic acid in the muscles is often associated with the occurrence of muscle fatigue and muscle pain, which will affect the comfort of doing physical exercise. At present, there are no drugs or officially recommended interventions to delay the appearance of muscle fatigue or muscle aches. This study assessed the effect of manual acupuncture on the comfort of physical exercise which was evaluated by assessing the mean levels of lactic acid, pulse, systolic and diastolic blood pressure, the Borg scale to assess the level of fatigue, and the Visual Analogue Scale (VAS) to assess muscle pain. Twenty-six patients were randomly divided into two groups, manual acupuncture (n = 13) and sham acupuncture (n = 13). Both groups received the same series of acupuncture, with 12 sessions spaced 1-3 days. Both groups also did the same physical exercise, which was a treadmill with moderate intensity for ten minutes, before and after the acupuncture therapy series. The average assessment of lactic acid levels, pulse rate, blood pressure, the Borg scale, and VAS was carried out twice, namely after physical exercise before starting the first therapy and after physical exercise after the last therapy. The results showed that there were significant differences in the average levels of lactic acid, pulse, systolic blood pressure, diastolic blood pressure, Borg scale, and VAS in the manual acupuncture group compared to sham acupuncture. Average lactic acid levels after acupuncture therapy 12 times (p = 0.041). Mean pulse rate after acupuncture therapy 12 times (p = 0.042). The mean systolic blood pressure after acupuncture therapy was 12 times (p = 0.024). Average diastolic blood pressure after acupuncture therapy 12 times (p = 0.035). Borg scale after acupuncture therapy 12 times (p = 0.043). VAS after acupuncture therapy 12 times (p = 0.049). These findings indicate that manual acupuncture therapy has a better effect on the comfort of physical exercise."

"Nyeri punggung bawah (NPB) adalah nyeri yang dirasakan di daerah punggung bagian bawah. NPB merupakan masalah kesehatan utama di masyarakat modern. 70 - 85% populasi akan mengalami NPB pada masa kehidupan mereka. Beberapa penelitian, tinjauan sistematis dan metaanalisis menunjukkan bahwa akupunktur dapat menghilangkan atau mengurangi rasa nyeri pada NPB. Banyak metode dan teknik rangsang yang digunakan dalam akupunktur, salah satunya adalah akupunktur pergelangan tangan dan pergelangan kaki. Teknik akupunktur ini mempunyai kelebihan yaitu meminimalkan penggunaan jumlah jarum dan rasa tak nyaman akibat sensasi penjaruman. Penelitian ini bertujuan untuk mengetahui pengaruh akupunktur pergelangan tangan dan pergelangan kaki terhadap skor NAS (Numeric Analog Scale) pada pasien NPB. Desain penelitian yang digunakan adalah uji klinis acak tersamar tunggal dengan kontrol. Penelitian ini melibatkan 42 pasien NPB yang dibagi menjadi 2 kelompok yaitu kelompok kontrol (n=21) yang dilakukan akupunktur tubuh dan kelompok perlakuan (n=21 yang dilakukan akupunktur pergelangan tangan dan pergelangan kaki.Hasil penelitian menunjukkan terjadi penurunan skor NAS yang signifikan pada kedua kelompok setelah terapi ke-3 dan ke-6. Perubahan skor NAS setelah terapi ke-3 pada kelompok perlakuan tidak berbeda bermakna bila dibandingkan dengan kelompok kontrol (p=0.319). Perubahan skor NAS setelah terapi ke-6 pada kelompok perlakuan berbeda bermakna bila dibandingkan dengan kelompok kontrol (p=0.041). Kesimpulan penelitian ini adalah akupunktur pergelangan tangan dan pergelangan kaki memiliki pengaruh terhadap skor NAS secara signifikan.

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Low back pain (LBP) is pain felt in the lower back area. NPB is a major health problem in modern society. 70-85% of the population will experience low back pain during their lives. Some studies, systematic reviews and meta-analyzes have shown that acupuncture can eliminate or reduce pain in LBP. Many methods and stimulation techniques used in acupuncture, one of which is wrist and ankle acupuncture. This technique has the advantage of minimizing the use of the number of needles and discomfort due to the pricking sensation.

This study aimed to determine the effect of wrist and ankle acupuncture to the NAS scores (Numeric Analog Scale) in patients with low back pain. The study design used was a single-blind randomized clinical trial with control. The study involved 42 patients with low back pain who were divided into 2 groups: control group (n = 21) were carried out body acupuncture and treatment group (n = 2) were carried out wrist and ankle acupuncture.

The results showed a decline in the NAS scores significantly in both group after the 3rd and 6th therapy. Changes in the NAS score after 3rd therapy in the treatment group was not significantly different when compared with the control group (p = 0.319). Changes in the NAS score after 6th therapy in the treatment group was significantly different when compared with the control group (p = 0.041). Conclusion of this study is wrist and ankle acupuncture have an effect on the NAS scores significantly."

"ABSTRAKLatar belakang:Migren adalah serangan nyeri kepala primer, bersifat spesifik,paroksismal, dengan atau tanpa aura, dengan manifestasi subjektif baik sebelummaupun sesudah serangan, merupakan nyeri kepala tipe kronik dengan gejala rekurensi,menyerang usia produktif dan dapat menyebabkan penurunan produktivitas kerja hingga80%, sehingga akan mempengaruhi kualitas hidup dan kehidupan perekonomian danpendidikan secara global yang mengarah kepada kerugian bagi penderita migren daninstitusi tempat penderita migren bersekolah ,bekerja serta dalam kehidupan keluargapenderita. Dengan tingginya angka prevalensi dan disabilitas pada penderita migren,dilain pihak sampai saat ini pengobatan yang tepat terhadap migren belum didapatkansecara maksimal maka diperlukan pendalaman dalam pengobatan maupun pencegahanmigren sangat dibutuhkan., dan sampai saat ini belum didapatkan obat yang pasti, baikterhadap pencegahan dan pengobatan, sehingga perlu dikembangkan terapi yang dapatmemberikan pertolongan yang lebih akurat pada penderita migrenTujuan penelitian ini adalah menilai keberhasilan dalam penatalaksanaan migren dalammengurangi frekuensi serangan, mengurangi intensitas serangan dan mengurangi durasiserangan dari minggu ke-0,ke-4 hingga ke-8. Metode: Uji klinis acak tersamar tunggaldengan kontrol dilakukan terhadap 34 subjek dengan migren yang dialokasikan secaraacak kedalam kelompok manual akupunktur (n=17), serta kelompok medikamentosa(n=17). Penilaian menilai frekuensi, durasi dan intensitas serangan migren yang dinilaipada saat sebelum perlakuan, minggu ke-4 dan minggu ke-8 dari baseline. Hasil: Hasilpenelitian menunjukkan terdapat perbedaan bermakna antara kedua kelompok padarerata jumlah frekuensi (p=0,040), durasi (p=0,012) dan intensitas (p=0,003) seranganmigren pada minggu ke-4 dibandingkan dengan medikamentosa. Serata terdapatperbedaan yang bermakna antara kedua kelompok pada rerata jumlah jumlah frekuensi(p=0,029), durasi (p=0,001) dan intensitas (p<0,001) serangan migren pada minggu ke-8. Kesimpulan: Intervensi akupunktur manual dapat menurunkan frekuensi, durasi danintensitas serangan migren lebih baik dibandingkan dengan preventif farmakologi asamvalproat pada minggu ke-4 dan minggu ke-8.

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ABSTARCTMigraine is a primary headache attack, specific, paroxysmal, with or without aura, with subjective manifestations both before and after the attack, a chronictype of headache with symptoms of recurrence, attacks at productive age and can cause a decrease in work productivity up to 80%, so that it will affect the quality of life, economic life and education globally which leads to losses for migraine sufferers andinstitutions where migraine sufferers attend school, work and in the lives of sufferersfamilies. With the high prevalence and disability rates for migraine sufferers, on theother hand, the right treatment for migraine has not yet been obtained to the maximum,it is necessary to deepen the treatment and prevention of migraine is needed, and untilnow there has been no definitive cure, both for prevention and treatment, so it isnecessary to develop therapies that can provide more accurate relief for migrainesufferers. The purpose of this study is to assess the success in managing migraine inreducing the frequency of attacks, reducing the intensity of attacks and reducing theduration of attacks from weeks 0, 4 to 8. Methods: A randomized controlled trial withcontrol was conducted on 34 subjects with migraine who were randomly allocated intothe manual group of acupuncture (n = 17), as well as the medicine group (n = 17). Theassessment of frequency, duration and intensity of migraine attacks assessed at the timebefore treatment, at the fourth and eight week from baseline. Results: The resultsshowed there were significant differences between the two groups in the mean numberof frequencies (p = 0.040), duration (p = 0.012) and intensity (p = 0.003) of migraineattacks at the fourth week. There were significant differences between the two groups inthe average number of frequencies (p= 0.029), duration (p=0.001) and intensity(p<0.001) of migraine attacks at the eight week. Conclusion: Manual acupunctureinterventions can reduce the frequency, duration and intensity of migraine attacksbetter than the use of valproic acid in the fourth and eight week."