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"While significant progress has been made in the past decade, the current understanding of protein aggregation and its consequences is still immature. Aggregation of Therapeutic Proteins provides an up-to-date resource on protein aggregation and its consequences, and available methods to control or slow down the aggregation process. This book also covers an overview on the causes, consequences, characterization, and control of the aggregation of therapeutic proteins. The knowledge in this book will help pharmaceutical scientists in the development of therapeutic proteins, and also instigate further scientific investigations in this area."

"Summary: There are more than 500 biopharmaceuticals on the market, including more than 200 therapeutic proteins, making biologics the fastest growing sector in the biopharmaceutical market. These products include more than 40 monoclonal antibodies, for indications ranging from treatment or mitigation of various types of cancer to rheumatoid arthritis. The clinical application of these therapeutic peptides and proteins is limited by several problems, such as lack of physical and chemical stability or the lack of desirable attributes for adequate absorption or distribution. Thus, as these therapeutic p"

"This book about application of NMR and molecular docking in structure-based drug discovery, NMR as a unique tool in assessment and complex determination of weak protein-protein Interactions, the use of residual dipolar coupling in studying proteins by NMR, studies of metalloproteins, recent developments in 15N NMR relaxation studies that probe protein backbone dynamics, contemporary methods in structure determination of membrane proteins by solution NMR, protein structure determination by solid-state NMR, and dynamic nuclear polarization : new methodology and applications."

"Fluorescent Proteins, devoted to the basic photophysical and photochemical aspects of fluorescent protein technology. The book provides a thorough understanding of primary molecular processes allowing the design of fluorescent proteins for specific applications."

"Fluorescent Proteins II highlights the physicochemical and biophysical aspects of fluorescent protein technology beyond imaging. It is tailored to meet the needs of physicists, chemists and biologists who are interested in the fundamental properties of fluorescent proteins, while also focussing on specific applications. The implementations described are cutting-edge studies and exemplify how the physical and chemical properties of fluorescent proteins can stimulate novel findings in life sciences."

"This volume brings together experts in the biochemistry, cellular biology, immunology and molecular biology of molecular chaperones and protein-folding catalysts with a focus on the mechanisms of cellular trafficking of these proteins and the role of these variegated trafficking mechanisms in both human and animal health and disease."