Hasil Pencarian  ::  Simpan CSV :: Kembali

"Tujuan: Mengumpulkan informasi mengenai penanganan dan komplikasi diabetes, serta kesadaran pengendaliandiri sendiri penderita diabetes di Indonesia. Studi ini juga mengevaluasi perspektif dokter, aspek psikologis, dankualitas hidup pasien.Metode: Studi non-intervensi, potong lintang, merekrut 1832 pasien dari pusat kesehatan sekunder dan tersierdi Indonesia. Data mengenai demografi , riwayat medis, faktor resiko, dan laporan pemeriksaan klinis termasuklaboratorium dikumpulkan dari rekam medis pasien. Sampel darah dikumpulkan untuk pengukuran HbA1c yangtersentralisasi.Hasil: Di antara 1832 pasien, 1785 individu memenuhi syarat untuk dianalisis. Rata-rata usia adalah 58,9+9,6tahun. Lamanya menderita diabetes 8,5+7,0 tahun. Mayoritas pasien (97,5%) menderita diabetes tipe 2.67,9% pasienmemiliki kontrol diabetes yang buruk (A1c: 8,1 ± 2,0%). 47,2% pasien memiliki kadar Glukosa Plasma Puasa >130mg/dL (161,6±14,6 mg/dL). Dislipidemia dilaporkan pada 60% pasien (834/1390) dan 74% (617/834) di antaranyamendapatkan obat hipolipidemik. Neuropati merupakan komplikasi paling umum (67.2%); komplikasi diabeteslainnya antara lain: katarak: 14.5% Retinopati diabetik non-proliferatif: 8.3%, kreatinin serum>2 mg/dl: 3.6%,ulkus yang sudah sembuh: 3.8%, angina pectoris 9.9% dan stroke 5.6%. Sekitar 81.3% pasien menerima terapi obathipoglikemik oral (OHO) (± insulin), 37,7% pasien menerima terapi insulin (±OHO). Penggunaan biguanide diikutioleh sulfonylurea. Mayoritas pasien menggunakan insulin manusia 73,2%, regimen premiks 58,5%, insulin analog24,9%. Mayoritas respon indeks kesehatan WHO-5 jatuh dalam teritori positif.Kesimpulan: Kontrol glikemik yang buruk pada mayoritas pasien diabetes perlu diperhatikan. Terdapat kebutuhan untukpenyesuaian terapi dari sebagian besar pasien menuju terapi farmakologis yang lebih intensif dan pendekatan multidisiplinerharus digunakan. Temuan studi ini perlu dikomunikasikan kepada pembuat kebijakan dan dokter untuk membantumereka memberikan perawatan kesehatan dan fasilitas yang baik.

---

AbstractAim: To collect information on diabetes management, diabetes complications, and awareness of self-control indiabetic population of the country. This study also evaluated the physician perspectives, psychological aspects, andquality of life of diabetic patients.Methods: This was a non-interventional, cross-sectional study, which recruited 1832 patients from secondary andtertiary medical centers across Indonesia. Data on demography, medical history, risk factors and clinical examinationreports including laboratory assessments were collected from medical records of patients. Blood samples of all patientswere collected for centralized HbA1c measurements.Results: Among 1832 patients, 1785 individuals were eligible for analysis. The mean age of the patients was 58.9+9.6years. The mean duration of diabetes was 8.5+7.0 years. Majority (97.5%) of the patients had type 2 diabetes. 67.9%had poor control of diabetes (A1c:8.1 ± 2.0%). 47.2% had FPG>130 mg/dL (161.6±14.6 mg/dL). Dyslipidemia wasreported in 60% (834/1390) and 74% (617/834) of those received lipid lowering treatment. Neuropathy was most commoncomplication (63.5%); other complications were: Diabetic retinopathy 42%, nephropathy 7.3%, severe late complications16.9%, macrovascular complications 16%, microvascular complications 27.6%. About 81.3% of patients were on OADs(± insulin), 37.7% were on insulin (±OADs). Majority used biguanides followed by sulfonylureas. Human insulin was usedby 73.2%, premix regimen 58.5%, analogues usage was 24.9%. Majority of the WHO-5 well being index responses fell inpositive territory.Conclusion: Poor glycaemic control in majority of patients is a concern. There is a need for a large proportion ofpatients to be adjusted to more intensive pharmacotherapy and a multi-disciplinary approach for management shouldbe adopted. The study fi ndings should be communicated to policymakers and physicians to help them provide properhealthcare and its facilities in Indonesia."

"ABSTRAKBackground: hypoglycemia is a major adverse event of insulin therapy for diabetes mellitus patients. The study was conducted to evaluate the incidence of hypoglycemia among insulin treated patients with type 1 diabetes mellitus (T1DM) or type 2 diabetes mellitus (T2DM) in the Indonesian cohort. Methods: this Indonesian cohort study consisted of retrospective and prospective evaluation of hypoglycemic episodes, using International Operations Hypoglycemia Assessment Tool (IO HAT) in 374 patients with diabetes (T1DM; n=17 or T2DM; n=357). The patients of ≥18 years of age and treated with insulin for >12 months were selected for this study (ClinicalTrials.gov number: NCT02306681). Results: a total of 374 patients were enrolled in this study and completed SAQ1. All patients with T1DM (17 [100%]), and 347 (97.2%) patients with T2DM completed SAQ2. Almost all the patients in the 4-week prospective period reported at least one hypoglycemic event (T1DM 100%, T2DM 99.4%) and the incidence rate of any hypoglycemia was 67.5 events per patient-year (PPY) and 25.7 events PPY for T1DM and T2DM patients, respectively. Among patients with T1DM and T2DM, 5.9% and 36.4%, respectively, did not know what hypoglycemia was at baseline, also high proportion of patients had impaired hypoglycemic awareness in the study (82.4% and 62.7%, respectively). Conclusion: overall, high proportion of patients reported hypoglycemic events in the prospective period indicating under reporting during the retrospective period due to recall bias. Therefore, there is a need for patient education program to improve the awareness of hypoglycemia in diabetes patient in Indonesia."

"Kaki diabetik merupakan komplikasi pada diabetes melitus (DM) tipe 2 tersering yang menyebabkan pasien menjalankan perawatan di rumah sakit. Penyulit lain pada DM tipe 2 berkontribusi terhadap peningkatan morbiditas dan mortalitas pasien. Terapi medik gizi pada pasien DM tipe 2 dan kaki diabetik dengan berbagai penyulit berperan penting dalam kontrol glikemik, mencegah perburukan status gizi, serta perbaikan penyembuhan luka. Serial kasus ini melibatkan empat pasien DM tipe 2 dan kaki diabetik dengan berbagai penyulit yang diberikan terapi medik gizi berupa asupan energi, makronutrien, mikronutrien, nutrien spesifik, dan edukasi gaya hidup. Pasien dilakukan pemantauan selama 19 hari sesuai fase proliferasi penyembuhan luka. Satu pasien dengan ketoasidosis diabetikum, satu pasien dengan hipertensi, dan dua pasien dengan diabetic kidney disease. Kontrol glikemik keempat pasien tercapai pada akhir perawatan di rumah sakit dan tidak didapatkan penurunan berat badan yang bermakna selama masa pemantauan. Penyembuhan luka berupa luka mengering, edema berkurang, dan timbulnya jaringan granulasi didapatkan pada tiga diantara empat pasien. Satu pasien tidak didapatkan penyembuhan luka yang signifikan karena adanya stenosis multipel pembuluh darah arteri di tungkai kiri. Terapi medik gizi pada pasien DM tipe 2 dan kaki diabetik dengan berbagai penyulit berperan pada perbaikan kontrol glikemik, mencegah perburukan status gizi, dan penyembuhan luka.

---

The most common cause of complication and hospitalization in type 2 diabetes mellitus (T2DM) patients are those associated with diabetic foot (DF). Complication of T2DM contribute to increasing morbidity and mortality. Medical nutrition therapy in patients with T2DM and DF with various complication plays an important role in management of glycemic control, worsening nutritional status, and repair wound healing. This case series include four patients T2DM and DF with various complication that given nutritional medical therapy consisting of energy intake, macronutrients, micronutrients, spesific nutrient, and healthy lifestyle education. Patients was monitored for 19 days according to the proliferation phase of wound healing. One patient with diabetic ketoacidosis, one patient with hypertension, and two patients with diabetic kidney disease. All patients got glycemic control during hospitalization. No significant weight loss was observed during monitoring period. Wounds in three of the four patients appeared to heal with dry wound, reduced edema, and formation of granulation tissue. One patient found insignificant wound healing due to multiple arterial stenosis in the left leg. Medical nutrition therapy with type 2 diabetes and diabetic foot with various complications plays an important role in management of glycemic control, preventing worsening nutritional status, and repair wound healing."

"Nefropati diabetik telah diketahui merupakan salah satu penyulit jangka panjang diabetes melitus (DM) yang berbahaya, yang dapat menyebabkan kegagalan ginjal tahap akhir. Namun, data adanya nefropati diabetik di antara pasien diabetes tipe 2 yang menjalani rawat jalan saat ini belum ada. Penelitian cross-sectional ini ditujukan untuk mengetahui prevalensi nefropati diabetik di antara penderita diabetes tipe 2 rawat jalan yang datang untuk pertama kalinya ke Klinik Metabolik dan Endokrinologi, RSUPN Dr. Cipto Mangunkusumo, Jakarta. Dari Desember 2001 sampai Juni 2002, 100 pasien baru diabetes tipe 2 diikutsertakan dalam studi. Empat puluh dua di antaranya adalah laki-laki dengan usia rata-rata 54 + 9,6 tahun. Overt nephropathy (makroalbuminuria) ditemukan pada 11% pasien, incipient nephropathy (mikroalbuminuria) terdapat pada 26% penderita, sedangkan sisanya normal (normoalbuminuria). Hasil penelitian menunjukkan bahwa lama sakit yang lebih dari 5 tahun menunjukkan korelasi bermakna dengan derajat albuminuria. Namun, tidak ada hubungan bermakna antara derajat albuminuria dengan faktor-faktor risiko lain, yaitu usia, dislipidemia, hipertensi, obesitas, dan kadar HbA1c. Semua pasien dengan overt nephropathy menunjukkan tes klirens kreatinin di bawah 75 ml/ menit (rerata 45,3 mL/menit), secara bermakna lebih rendah dari pasien dengan mikro- atau normoalbuminuria (p=0,01). Retinopati ditemukan pada 10 dari 11 (90%) pasien dengan overt nephropathy. Analisis multivariat memperlihatkan bahwa lama sakit dan retinopati secara bermakna berkorelasi dengan terjadinya nefropati diabetik (p < 0,05). Sebagai kesimpulan dapat dikatakan bahwa prevalensi nefropati diabetik (yaitu overt nephropathy dengan retinopati) di antara pasien diabetes tipe 2 rawat jalan adalah 10%. Lama sakit merupakan faktor risiko penting bagi timbulnya penyulit ini. (Med J Indones 2004; 13: 161-5)

---

Diabetic nephropathy has been known as one of the most serious long-term complications of diabetes mellitus (DM), which could lead to end-stage kidney failure. However, data showing the presence of diabetic nephropathy among ambulatory type 2 diabetic patients is currently not available. This cross-sectional study was conducted to find the prevalence of diabetic nephropathy among non-hospitalized type 2 diabetic patients, who came for the first time to the Metabolic and Endocrinology Clinic, Dr. Cipto Mangunkusumo Hospital, Jakarta. From December 2001 to June 2002, 100 new type 2 diabetic patients were included in the study. Forty-two of them were men and the mean age was 54 + 9.6 years. Overt nephropathy (macroalbuminuria) was found in 11% of patients, while incipient nephropathy (microalbuminuria) was 26%, and the rest were normal (normoalbuminuria). Duration of illness of more than 5 years was significantly correlated with the degree of albuminuria. However, there is no significant correlation between the degree of albuminuria and other risk factors, i.e. patient’s age, dyslipidemia, hypertension, obesity, HbA1c level. All patients with overt nephropathy had creatinine clearance test below 75 ml/ min. (mean 45.3 mL/min), significantly lower than patients with micro- or normoalbuminuria (p=0.01). Retinopathy was found in 10 out of 11 (90%) patients with overt nephropathy. Multivariate analysis showed that the duration of illness and retinopathy was significantly correlated with the presence of diabetic nephropathy (p< 0.05). We concluded that the prevalence of diabetic nephropathy (i.e. overt nephropathy with retinopathy) among non-hospitalized type 2 diabetic patients was 10%. The duration of illness was an important risk factor for the development of this complication. (Med J Indones 2004; 13: 161-5)"

"Penelitian ini bertujuan untuk mengetahui hubungan antara profil lipid darah dengan derajat retinopati diabetik penderita DM tipe-2. Penelitian potong-lintang pada 52 pasien retinopati diabetika dilaksanakan di Poliklinik Mata, Rumah Sakit Cipto Mangunkusumo, Jakarta. Data yang dikumpulkan meliputi data demografi, gaya hidup, lama menderita DM, pemeriksaan fisik dan antropometrik, asupan lemak, asam lemak dan kolesterol data kadar gula darah puasa, A1C, kolesterol total, kolesterol-LDL, kolesterol-HDL and trigliserida, dan pemeriksaan fundus. Analisis statistik yang digunakan adalah uji chi-square untuk mengetahui hubungan antara profil lipid darah dengan derajat retinopati diabetik. Subyek terdiri dari 20 orang laki-laki dan 32 orang perempuan dengan rerata usia 53,8 ± 5,2 tahun. Sebanyak 53,8% telah didiagnosis DM selama >10 tahun, dengan rerata IMT adalah 24,1 ± 3,3 kg/m2 dan 38,5% diklasifikasikan sebagai obes I dan II. Rerata kadar gula darah puasa 157,5 ± 71,8 mg/dL, dan A1C 9,1 ± 2,4 %. Sebanyak 40,4% subyek mempunyai kadar kolesterol total darah tinggi, 34,6% kadar kolesterol-LDL darah sangat tinggi, dan 65,4% dengan kolesterol-HDL dan trigliserida darah normal. Derajat keparahan retinopati diabetika ditunjukkan dengan adanya 61,6% subyek dengan retinopati diabetika non-proliferasi berat (NPDR) and retinopati diabetika proliferasi (PDR). Kesimpulannya, belum dapat dibuktikan adanya hubungan yang bermakna antara profil lipid dengan derajat retinopati diabetika.

---

This study aimed to determine the relationship between plasma lipid profile and the severity of diabetic retinopathy in type 2 diabetes patients. A cross sectional study was done in Ophthalmologic Clinic, Cipto Mangunkusumo General Hospital, Jakarta for 52 diabetic retinopathy (DR) patients. Data collected were demographic, life style, duration of diabetes, physical and antropometric examinations, fat, fatty acid and cholesterol intake, fasting plasma glucose, A1C, total-, LDL-, HDL-cholesterol and triglyceride level, and fundus examination.

Statistical analysis was done using chi-square test to see the associations between plasma lipid profile and DR in type 2 diabetes patients. Subjects comprised of 20 males and 32 females diabetes patients with mean age of 53.8 ± 5.2 years. As much as 53.8% had been diagnosed as DM for >10 years. The mean value of BMI was 24.1 ± 3.3 kg/m2 and 38.5% were classified as obese I and II. The mean value of fasting plasma glucose was 157.5 ± 71.8 mg/dL, and A1C was 9.1 ± 2.4 %.

For lipid profile, 40.4% had high total cholesterol level (>240 mg/dL), 34.6% had high and very high LDL-cholesterol level (≥160 mg/dL), and 65.4% had normal HDL-cholesterol (40-60 mg/dL) and triglyceride level (<150 mg/dL). For the severity of retinopathy, 61.6% had severe non-proliferative diabetic retinopahy (NPDR) and proliferative diabetic retinopahy (PDR). In conclusion, there were no significant associations between plasma lipid profile and the severity of diabetic retinopathy."

"Aktivitas fisik sebagai salah satu pilar penatalaksanaan Diabetes Mellitus dan pemeriksaan HbAlc sebagai evaluasi kendali gula darah jangka panjang seringkali tidak digunakan. Penelitian ini bertujuan untuk menilai fisibilitas dan efektivitas aktivitas fisik dan kendali gula darah pada penyandang DM tipe 2 di masyarakat pada umumnya. Studi menggunakan desain kohort prospektif dengan 5 bulan masa pengamatan (12 November 2007 - 9 April 2008) dan 2 lokasi pengambilan sampel: di kelompok senam DM (persadia) dan di poliklinik DM RS Husada, Jakarta. Pengambilan sampel dilakukan dengan metode non-random sampling secara consecutive selama 2 bulan masa enrollment. Sampel adalah 95 orang penyandang DM tipe 2 yang telah menandatangani formulir informed consent. Variabel independen utama adalah aktivitas fisik yang dinilai baik dari segi frekuensi, durasi, intensitas maupun kompositnya, menggunakan kuesioner yang telah divalidasi. Sedangkan variabel dependen-nya adalah kendali gula darah yang dinilai dari kadar HbAlc plasma vena darah dalam persen. Data dikumpulkan dan diukur dua kali: pada awal dan akhir penelitian (minimal 12 minggu setelah data pertama diambil). Analisis multivariat dilakukan dengan Regresi Cox Proportional Hazard menggunakan perangkat STATA versi 9.2. Hasil penelitian ini menemukan adanya hubungan antara aktivitas fisik dan kendali gula darah pada 95 orang penyandang DM tipe 2 di RS Husada Jakarta (HRadjusted = 0,54; 95%CI 0,27-1,11) selelah dikQntrol terhadap variabel pengobatan dan pola konsumsi serat. Dengan demikian, tenaga kesehatan tidak perlu lagi ragu-ragu untuk menganjurkan para penyandang DM tipe 2 untuk mengintegrasikan aktivitas fisik ke dalam kehidupan mereka sehari-hari guna memperbaiki kendali gula darahnya.

---

Physical acitivity is often underutilized as one of the cornerstones of diabetes management and so is the use of HbAlc in long-term glycemic control. The purpose of this study is to assess the feasibility and effectiveness of physical activity and blood glucose control among diabetes type 2 patients in general population.

A prospective cohort study design was used to conduct the study for a period of 5 months (l2th November 2007 - 9th April 2008) using 2 catchment areas: diabetes exercise club (persadia) and diabetes policlinic Husada Hospital, Jakarta. A non-random (consecutive) sampling technique during a 2-month enrollment period yielded a participation of 95 type 2 diabetes patients as study subjects, all of whom have signed informed consents.

The main independent variable assessed was physical activity in the forms of frequency, duration, intensity and composite using validated questionnaires whilst the outcome of blood glucose control expressed as percentage of plama venous HbAlc. Data were collected twice: at baseline and at least 12 weeks after. Multivariate analysis was conducted using Cox Proportional Hazard Regression and the software STATA 9.2 version.

Results from the study found an association between physical activity and blood glucose control among 95 diabetes type 2 patients in Husada Hospital Jakarta (HRadjusted = 0,54; 95%CI 0,27-1,11) after adjusting for drug therapy and dietary pattern consumption of fibre. ThUs. health care providers should not be hesitant to advice diabetics patients to integrate physical activity into their daily lives in order to improve their glycemic control."

"Diabetes melitus tipe 2 merupakan penyakit kronis yang dapat menimbulkan berbagai komplikasi. Komplikasi diabetes melitus yang berdampak terhadap kondisi fisiologis maupun psikologis memerlukan proses adaptasi. Tujuan laporan ini yaitu untuk menganalisis penerapan teori adaptasi Roy dalam proses asuhan keperawatan pada pasien dengan diabetes melitus tipe 2 disertai dengan berbagai komplikasi melalui metode studi kasus dan studi literatur. Hasil menunjukkan masalah utama adalah kerusakan integritas kulit dan resiko ketidakstabilan kadar glukosa darah serta kurangnya pengetahuan terkait manajemen diabetes melitus, dimana intervensi utama dalam laporan ini yaitu untuk meningkatkan proses adaptasi klien dengan diabetes melitus tipe 2 yaitu meningkat pemahaman terkait manajemen diabetes melitus secara mandiri. Kesimpulan: konsep adaptasi Roy dapat diterapkan dalam asuhan keperawatan pada pasien diabetes melitus tipe 2 dengan komplikasi ulkus diabetik dan gagal ginjal kronik.

---

Diabetes mellitus type 2 is a chronic disease that can cause various complications. Complications of diabetes mellitus that affect the physiological and psychological conditions require adaptation process. The purpose of this report is to analyze the application of Roy 39;s adaptation theory in the process of nursing care in patients with type 2 diabetes mellitus with various complications through case study method and literature study. The results indicate the major problem are the deterioration of skin integrity, the risk of instability of blood glucose levels and the lack of knowledge related to diabetes mellitus management, where the main intervention in this report is to improve the adaptation process of clients with diabetes mellitus type 2, by increasing understanding of diabetes mellitus management independently. Conclusion: Roy 39;s adaptation concept can be applied in nursing care in type 2 diabetes mellitus patients with complications of diabetic ulcers and chronic kidney diseases "

"ABSTRAKBackground: periodontitis is a major cause of chronic infection in diabetic patients. Diabetic patients have four-fold risk of having cardiovascular disease. Chronic inflammation caused by periodontitis, a non-traditional cardiovascular risk factor is widely known to play a major role in atherogenesis. Among non-diabetics, an association has been found between periodontitis and arterial stiffness, but in diabetic patients the result is inconsistent. No study has investigated either the proportion of periodontitis or its correlation with arterial stiffness in type 2 diabetes population in Indonesia. Methods: this study was a cross-sectional study involving 97 patients with type 2 diabetics, who were recruited on Endocrinology Clinic from April to August 2017. Periodontitis was measured for pocket depth, clinical attachment loss and bleeding on probing by a periodontist. Carotid-femoral PWV (Pulse Wave Velocity) was measured using SphygmoCor Xcel with cuff-based tonometry technique. Results: periodontitis was found in 99% type 2 diabetic subjects and 78% of them had severe periodontitis. There was no significant correlation found between pocket depth, clinical attachment loss and cfPWV (r=0.024, p=0.407 and r=0.011, p=0.456); whereas there was a weak positive correlation between pocket depth and PWV (r=0.294, p=0.041) in well-controlled type 2 diabetics. Conclusion: most of type-2 diabetics had severe periodontitis; however, the correlation between periodontitis and arterial stiffness could not be concluded in this study."

"Latar Belakang: Peningkatan kadar high sensitivity C-reactive protein ( hsCRP ) dan kekakuan arteri berhubungan dengan peningkatan insiden kejadian kardiovaskular dan peningkatan mortalitas akibat penyakit jantung koroner pada pasien diabetes melitus tipe 2.Tujuan: Tujuan dari penelitian ini adalah untuk mengetahui hubungan antara kadar hsCRP dan kekakuan arteri pada pasien diabetes melitus tipe 2.Metode : Melalui studi cross-sectional, dilakukan pemeriksaan kadar hsCRP dan derajat kekakuan arteri karotis pada 40 pasien dengan diabetes melitus tipe 2. Kekakuan arteri karotis kommunis diperiksa dengan doppler echotracking system untuk menentukan pulse wave velocity (PWV) atau kekakuan arteri karotis lokal (carotid-PWV).Hasil : Nilai median hsCRP pada penelitian ini adalah 4,5 (0,2 - 18,9) mg/L dan nilai rata-rata kekakuan arteri karotis adalah 8,8 ±1,7 m/detik. hsCRP berkorelasi kuat dengan karotid-PWV (r = 0,503, P = 0,001). Korelasi hsCRP dengan karotid-PWV ini tetap terlihat setelah dilakukan koreksi terhadap umur, indeks masa tubuh dan mean arterial pressure (r = 0,450, P = 0,005).Kesimpulan : Setelah dilakukan koreksi terhadap umur, indeks masa tubuh dan mean arterial pressure, hsCRP berkorelasi positif cukup kuat dengan kekakuan arteri pada pasien diabetes melitus tipe 2.

---

Background: The elevated level of high-sensitivity C-reactive protein (hsCRP) and arterial stiffness are associated with higher incidences of cardiovascular events and with increased mortality from coronary heart disease in type 2 diabetic patients.

Aim: The aim of this study was to investigate the relationship between hsCRP and arterial stiffness in type 2 diabetic patients.

Methods: A cross-sectional study was conducted to assess the plasma levels of high sensitive C-reactive protein and carotid arterial stiffness among 40 patients with type 2 diabetes mellitus. The common carotid artery was studied by a doppler echotracking system to determine the local carotid pulse wave velocity (carotid-PWV).

Results: The median value of hsCRP in this study was 4.5 (0.2 to 18.9) mg/L and the average value of local carotid stiffness was 8.8 ± 1.7 m/sec. hsCRP showed a strong correlation with carotid-PWV (r = 0.503, P = 0.001). Levels of hsCRP were independently associated with carotid-PWV after adjusting for age, body mass index, and mean arterial pressure (r = 0,450, P = 0,005).

Conclusion: After adjusting for age, body mass index, and mean arterial pressure, hsCRP was strongly positively correlated with arterial stiffness in patients with type 2 diabets mellitus."