Hasil Pencarian

Ditemukan 18422 dokumen yang sesuai dengan query

Parathyroid carcinoma: review of a problematic case

"Karsinoma paratiroid merupakan neoplasma yang jarang ditemukan, dengan frekuensi kurang dari 1% dari seluruh kasus hiperparatiroidisme primer. Beberapa gambaran klinis dan biokimiawi dapat mengarahkan pada karsinoma paratiroid namun diagnosis pre dan intraoperatif yang akurat masih sulit ditegakkan. Studi ini melaporkan satu kasus karsinoma paratiroid yang terdiagnosis pasca-operasi. Intraoperatif ditemukan pembesaran kelenjar paratiroid yang telah menginfiltrasi laringeus rekuren dan kelenjar tiroid kanan. Hasil histopatologik menunjukkan nodul tumor yang dipisahkan oleh jaringan ikat tebal, disertai invasi pada kapsul dan jaringan sekitar. Diagnosis akhir karsinoma paratiroid ditegakkan berdasarkan gambaran klinis dan pemeriksaan spesimen

Abstract

Karsinoma paratiroid merupakan neoplasma yang jarang ditemukan, dengan frekuensi kurang dari 1% dari seluruh kasus hiperparatiroidisme primer. Beberapa gambaran klinis dan biokimiawi dapat mengarahkan pada karsinoma paratiroid namun diagnosis pre dan intraoperatif yang akurat masih sulit ditegakkan. Studi ini melaporkan satu kasus karsinoma paratiroid yang terdiagnosis pasca-operasi. Intraoperatif ditemukan pembesaran kelenjar paratiroid yang telah menginfiltrasi laringeus rekuren dan kelenjar tiroid kanan. Hasil histopatologik menunjukkan nodul tumor yang dipisahkan oleh jaringan ikat tebal, disertai invasi pada kapsul dan jaringan sekitar. Diagnosis akhir karsinoma paratiroid ditegakkan berdasarkan gambaran klinis dan pemeriksaan spesimen"

[Fakultas Kedokteran Universitas Indonesia, Fakultas Kedokteran Universitas Indonesia], 2012

pdf

Artikel Jurnal Universitas Indonesia Library

Handbook of parathyroid diseases : a case-based practical guide / Aliya A. Khan, Orlo H. Clark, editors

"The Handbook on parathyroid diseases presents a comprehensive and concise overview of our current knowledge in the area of parathyroid function, hormone regulation and disease states. The handbook educates the reader using a case-based approach presenting current evidence in the field. The material is presented in an easy to read and understandable language and uses a plethora of tables and text boxes where possible. Complex concepts are conveyed in simple and clear language. Leading international experts contribute to this state of the art book providing a true depth of knowledge and practicality."

New York: Springer, 2012

e20426076

eBooks Universitas Indonesia Library

Licata, Angelo A., edtor

Diseases of the parathyroid glands

"For practitioners at all stages of experience, diseases of the parathyroid glands are not easily deciphered. There are many subtleties to its pathology and diagnosis. Today, the wealth of new information from molecular medicine makes it very challenging for the individual practitioner to have a complete picture of these entities. Diseases of the parathyroid glands addresses these issues by offering a concise, user-friendly text that provides state-of-the-art background on mineral physiology and its regulation and couples this to a variety of clinical topics of parathyroid gland pathology. Introductory chapters cover calcium regulation and parathyroid gland physiology, drawing upon many of the new aspects of glandular control mechanisms beyond the classical ones associated with calcium alone. The majority of the text covers clinical problems. Although most chapters address problems in adult medicine, three separate chapters are devoted to pediatric problems of hyper- and hypoparathyroidsm and parathormone resistance states. In addition, there are several chapters on less common but equally challenging problems such as parathyroid cancer, calciphylaxis, cystic lesions of the glands, and ectopic glandular disease. The final chapters detail the techniques of parathyroid gland imaging and surgical treatment. "

New York: Springer, 2012

e20425896

eBooks Universitas Indonesia Library

Oertli, Daniel

Surgery of the thyroid and parathyroid glands

"This book is a unique in-depth and comprehensive reference that covers all surgically relevant thyroid and parathyroid diseases and presents the latest information on their management. International authorities discuss operative techniques and treatments in detail and explain the rationales for their favored approaches. The topics of this second edition include the description of surgically relevant pathologies, preoperative surgical evaluation, decision making, and operative strategies for the various thyroid and parathyroid diseases. In addition, experts present the molecular basis for thyroid neoplasia, review the current understanding of the genetics of inherited thyroid and parathyroid diseases, and discuss the management of recurrent and locally invasive thyroid cancer. Evolving modern operative techniques such as neuromonitoring and minimally invasive (videoscopic) approaches to the thyroid and parathyroids are also covered."

Berlin : Springer, 2012

e20425976

eBooks Universitas Indonesia Library

Ultrasound of the thyroid and parathyroid glands

"This highly illustrated book, complete with comprehensive clinical references and annotated images, will serve as a leading text to educate head and neck surgeons, endocrinologists, and radiologists on the basics and nuances of thyroid and parathyroid ultrasound. It emphasizes the use of ultrasound as an office-based modality by clinicians and radiologists who actively care for this special set of patients. This text uniquely combines the collaboration between a clinician/surgeon and radiologist who share their extensive experience in head and neck ultrasound."

New York: Springer, 2012

e20420760

eBooks Universitas Indonesia Library

I Wayan Wisnu Brata

Ekspresi Parathyroid Hormone-Related Protein (PTHrP) Sebagai Prediktor Metastasis Tulang Pada Karsinoma Payudara Subtipe Luminal = Expression of Parathyroid Hormone-Related Protein (PTHrP) As a Predictor of Bone Metastasis in Luminal Subtype of Breast Cancer

ABSTRAK

Nama : I Wayan Wisnu Latar belakang: Kanker payudara (KPD) merupakan kanker yang paling sering terjadi pada wanita di seluruh dunia. Pada tahun 2020, KPD merupakan kasus kanker baru terbanyak di Indonesia dengan 65,858 kasus dan kematian 22,430 kasus. Namun, 90% kematian tersebut disebabkan karena proses metastasis. KPD sering bermetastasis ke tulang (70-80%) dalam kurun waktu 18-20 bulan setelah ditegakkannya diagnosis. PTHrP (Parathyroid Hormone-related Protein) diduga berhubungan dengan KPD yang bermetastasis ke tulang dan menandakan perjalanan klinis KPD yang lebih agresif. PTHrP dapat muncul sebagai alat diagnostik prabedah penting dan memberi gambaran kesintasan pasien yang mengalami metastasis tulang. Tujuan: Studi ini bertujuan untuk melihat hubungan ekspresi PTHrP dengan kejadian metastasis tulang pada karsinoma payudara subtipe luminal (KPDL). Metode: Penelitian ini adalah penelitian analitik dengan desain studi case control. Sampel diambil dengan cara consecutive sampling. Kriteria inklusi adalah pasien KPDL yang dilakukan biopsi atau operasi dan menjalani terapi di bagian Bedah Onkologi RSUP Dr. Cipto Mangunkusumo dan terdapat blok paraffin yang layak diproses. Data klinikopatologis seperti usia, indeks massa tubuh, ukuran tumor, keterlibatan KGB, dan stadium kanker diperoleh dari rekam medis. Dilakukan pewarnaan imunohistokimia dengan reagen AB75150 pada jaringan tumor payudara yang tersimpan dan tingkat ekspresi PTHrP disajikan dalam bentuk h-score. Analisis statistik dilakukan menggunakan program SPSS 27.0. Hasil: Didapatkan 45 sampel dengan 18 sampel dengan metastasis ke tulang dan 27 sampel tidak dengan metastasis ke tulang. Dari analisis data, didapatkan hubungan yang signifikan antara ekspresi PTHrP dengan kejadian metastasis tulang pada sampel KPDL (p = <0,001) dengan OR 31,2 (IK95% 5,3 – 185). OS sampel dengan ekspresi PTHrP kuat adalah 20.5% dengan HR 7.3 (IK95% 2-26.6). Proporsi ekspresi PTHrP kuat pada metastasis tulang 83%. Proporsi ekspresi kuat PTHrP pada KPDL sebesar 48.9 %. Kesimpulan: Peningkatan ekspresi PTHrP memiliki hubungan yang signifikan dengan kejadian metastasis tulang pada pasien KPDL serta OS yang lebih rendah.

Introduction: Breast cancer (BC) is the most common cancer in women throughout the world. In 2020, BC was the largest number of new cancer cases in Indonesia with 65,858 cases and 22,430 deaths. However, 90% of deaths are caused by the metastatic process. BC often metastasizes to the bones (70-80%) within 18-20 months after diagnosis. PTHrP (Parathyroid Hormone-related Protein) is thought to be associated with BC that metastasizes to the bone and indicates a more aggressive clinical course of breast cancer. PTHrP may emerge as an important presurgical diagnostic tool and provide insight into the survival of patients presenting with bone metastases. There has been no research that states a specific relationship between PTHrP and luminal subtype BC. Objective: This study aims to examine the relationship between PTHrP expression and the incidence of bone metastases in luminal subtype BC. Methods: This research is an analytical study with a case control study design. Samples were taken by consecutive sampling according to the inclusion and exclusion criteria. Inclusion criteria were patients with luminal subtype BC who underwent biopsy or surgery and underwent therapy in the Surgical Oncology department of Dr. RSUP. Cipto Mangunkusumo and there are paraffin blocks that are suitable for processing. Clinicopathological data such as age, body mass index, tumor size, lymph node involvement, and cancer stage were obtained from medical records. Immunohistochemical staining was carried out on stored breast tissue and the PTHrP expression level was presented in the form of an H-score. Statistical analysis was carried out using the SPSS 27.0 program. Results: There were 45 samples obtained with 18 samples with bone metastases and 27 samples without bone metastases. From data analysis, a significant relationship was found between PTHrP expression and the incidence of bone metastases in luminal subtype BC samples (p = <0.001) with OR 31.2 (95% CI 5.3 – 185). OS of samples with strong PTHrP expression was 20.5% with HR 7.3 (95% CI 2-26.6). The proportion of strong PTHrP expression in bone metastases was 83%. The proportion of strong expression of PTHrP in luminal subtype BC was 48.9%. Conclusion: Increased PTHrP expression has a significant association with the incidence of bone metastases in luminal subtype BC patients as well as lower OS."

Jakarta: Fakultas Kedokteran Universitas Indonesia, 2024

SP-pdf

UI - Tugas Akhir Universitas Indonesia Library

Ian Huang author

A rare case of upper back pain as the presenting complaint of acute myocardial infarction / Ian Huang, Raymond Pranata, Novita

"ABSTRAK

Acute upper back pain as one of the atypical symptoms of acute myocardial infarction (AMI) is more frequently encountered in women, elderly, diabetics, and patients with prior stroke or heart failure.1 Failure to recognize atypical clinical presentation of AMI conveys to delayed diagnosis, which are associated with increased morbidity and mortality.2 Abstract : Acute upper back pain as one of the atypical symptoms of acute myocardial infarction (AMI) is more frequently encountered in women, elderly and diabetics. Failure to recognize atypical clinical presentation of AMI conveys to delayed diagnosis, which are associated with increased morbidity and mortality. Herein we report a case of 46 yearsold male presenting with a sudden onset of severe acute upper back pain 6 hours prior to hospital admission. Diagnosis of AMI was delayed until 12 hours later after typical ischemic chest pain manifested and ECG reading showed evolution of ST-Elevation Myocardial In- farction (STEMI). Due to the atypical clinical presentation, diagnosis of AMI in this patient was delayed. Vigilant observation and low threshold for acute coronary syndrome (ACS) work-up are obligatory to prevent delayed diagnosis and management.

Bandung : Faculty of Medicine, Universitas Padjadjaran, 2016

CHEST 3:4 (2016)

Artikel Jurnal Universitas Indonesia Library

Case studies in the neuropsychology of vision

Church Road: Psychology Press, 1999

612.8 CAS

Buku Teks SO Universitas Indonesia Library

Jones, Katherine R. Indoe

Nephrologic nursing case studies: a compilation of 47 case histories

New York: Medical examination , 1982

616.61 JON n

Buku Teks SO Universitas Indonesia Library

Rohayati Rahafat

Pengembangan alat ukur kualitas hidup terkait kesehatan pada pasien penyakit jantung koroner studi kasus di RSUD Pasar Rebo Jakarta = Development of measuring health related quality of life of coronary heart disease patients case studies in Hospital Pasar Rebo Jakarta

"Metode pengukuran kualitas hidup manusia yang terkait dengan kesehatan sudah berkembang selama ini di negara-negara maju. Pola pengukuran yang ada mencakup berbagai macam atribut yang dipergunakan untuk mengukur status kesehatan perorangan, yang secara umum melibatkan fungsi dari organ tubuh baik secara fisik maupun non fisik.

Indonesia sebagai salah satu negara berkembang dengan berbagai macam jenis penyakit, teknik evaluasi Ekonomi Kesehatan yang menggunakan alat ukur kualitas hidup sangat jarang dilakukan di Indonesia. Terkait dengan hal tersebut, maka permasalahannya adalah : Belum diketahuinya aplikasi model HRQol pada pengukuran status kesehatan dari pasien penyakit jantung koroner di Indonesia.

Kerangka konsep yang diajukan dimulai dengan studi literatur dan peer review dengan para ahli untuk membandingkan dan mengklasifikasikan alat ukur MacNew yang disesuaikan dengan kondisi pasien penyakit jantung di Indonesia. Dilakukan 2 kali uji coba pada pasien di RSUD Pasar Rebo yang kemudian menghasilkan 16 atribut yang valid dan reliabel, yaitu: pusing, kebahagiaan, kemandirian, kegiatan sosial, gangguan pernapasan, dada sakit, kaki sakit, olahraga/latihan terbatas, rendah diri, gelisah, tidak berharga, keterbatasan fisik, frustasi, proteksi, terbebani dan sosialisasi.

Dilakukan pengukuran nilai utility yang didapat yaitu nilai rata-rata Utility untuk tiap atrbut adalah 40,51. Dengan Pearson Chi-square (p<0,05) terlihat bahwa atribut Sosialisasi memiliki korelasi terkuat dengan atribut-atribut lain yaitu: pusing, kebahagiaan, kemandirian, kegiatan sosial, gangguan pernapasan, dada sakit, kaki sakit, olahraga/latihan terbatas, rendah diri, gelisah, tidak berharga, keterbatasan fisik, frustasi, proteksi, terbebani.

The human quality of life measurement methods related to health have been developed in many countries. Measurement patterns include a variety of attributes that are used to measure the health status of individuals, which generally involve the functions of organs, both physical and non physical.
Indonesia as a developing country with many kinds of disease, Health Economic evaluation techniques that use instruments to measure the quality of life is very rarely done in Indonesia. Related to that, then the problem is not many application model: HRQol in the measurement of health status of the patients with coronary heart disease in Indonesia.
The proposed draft framework began with the study of literature and peer review by experts to compare and classify MacNew measurement tool based on patient's heart disease conditions in Indonesia. Done 2 time trials on patients in Pasar Rebo Hospital with 16 attributes valid and reliability, including: dizziness, happiness, independence, social events, respiratory disorder, chest pain, leg pain, sports/exercise limited, low self-esteem, anxiety, not valuable, physical limitations, frustrating, protection, burdened and socialization.
The measurement value of the utility obtained the average value for each atrbut Utility is 40,51. The Pearson Chi-square (p < 0.05) looks that have the strongest correlation Socialization attribute with another attribute-attribute are: dizziness, happiness, independence, social events, respiratory disorder, chest pain, leg pain, sports/exercise limited, low self-esteem, anxiety, not valuable, physical limitations, frustrating, protection, burdened"

Depok: Fakultas Kesehatan Masyarakat Universitas Indonesia, 2013

T-Pdf

UI - Tesis Membership Universitas Indonesia Library

<< 1 2 3 4 5 6 7 8 9 10 >>

Hasil Pencarian :: Simpan CSV :: Kembali

Hasil Pencarian