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Yoshua Christian Hendrik
"Pendahuluan: Ikan teri jengki (Stolephorus insularis) mengandung fluor dalam bentuk senyawa CaF2.
Tujuan: Menganalisis perubahan kekerasan mikro permukaan email setelah pemberian ikan teri jengki.
Metode: Perlakuan dilakukan pada 9 gigi tikus Sprague dawley yang terbagi menjadi kelompok baseline, perlakuan pakan teri, perlakuan oles larutan teri, kontrol negatif pakan, dan kontrol negatif akuades.
Hasil: Nilai kekerasan Vickers pemberian ikan teri jengki metode pakan (440.30 ± 24.72) dan oles (510.32 ± 35.72) lebih tinggi bermakna daripada kontrolnya (315.80 ± 17.51) dan (347.28 ± 28.56).
Kesimpulan: Penggunaan ikan teri jengki metode oles lebih efektif dalam meningkatkan kekerasan email dibandingkan metode pemberian pakan.

Introductions: Anchovies (Stolephorus insularis) contain high enough fluor in the form of CaF2.
Aim: To analyze the alteration of enamel microhardness after anchovy substrate application.
Method: Treatment was done on 9 incisors of Sprague dawley rats, comprised from groups which were baseline, feeding application, topical application, negative control of feeding, and negative control of topical.
Results: Vickers hardness number of anchovies consumption by feeding (440.3 ± 24.72) and topical solution (510.32 ± 35.72) is statistically higher than its negative control (315.80 ± 17.51) and (347.28 ± 28.56).
Conclusion: The use of anchovy (Stolephorus insularis) by topical is proven more effective in increasing the microhardness of tooth enamel surface."
Depok: Universitas Indonesia, 2012
S45576
UI - Skripsi Membership  Universitas Indonesia Library
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Felix Triputra
"Pendahuluan: Ikan teri jengki (Stolephorus insularis) mengandung fluor dalam bentuk senyawa CaF2 yang berperan dalam fluoridasi.
Tujuan: Menganalisis perubahan ketahanan terhadap asam permukaan email setelah pemberian ikan teri jengki.
Metode: Perlakuan dilakukan pada 9 gigi tikus Sprague dawley yang terbagi menjadi kelompok baseline, perlakuan pakan teri, perlakuan oles larutan teri, kontrol negatif pakan, dan kontrol negatif akuades.
Hasil: Nilai ketahanan terhadap asam meningkat dilihat melalui kerusakan permukaan email dan perubahan kekerasan mikro permukaan email setelah pemaparan asam fosfat 50% selama 60 detik.
Kesimpulan: ikan teri jengki dapat digunakan sebagai alternatif bahan fluoridasi.

Introductions: Anchovies (Stolephorus insularis) contain high enough fluor in the form of CaF2 and functioning as fluoridation material.
Aim: To analyze the alteration of enamel solubility towards acid after anchovy substrate application.
Method: Treatment was done on 9 incisors of Sprague dawley rats, comprised from groups which were baseline, feeding application, topical application, negative control of feeding, and negative control of topical.
Results: From the enamel surface destruction and email surface microscopic hardness shifting there is a decrease in enamel solubility towards acid after anchovy substrate application.
Conclusion: Stolephorus insularis can be used as an alternative material of fluoridation.
"
Jakarta: Fakultas Kedokteran Gigi Universitas Indonesia, 2012
S45405
UI - Skripsi Membership  Universitas Indonesia Library
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Stephanie Zabrina
"Pemanfaatan sumber daya alam Indonesia seperti ikan teri jengki (Stolephorus insularis), yang mengandung konsentrasi fluor tinggi (CaF2), perlu dikembangkan untuk fluoridasi topikal. Penelitian eksperimental laboratorik in vivo menggunakan 14 ekor tikus Sprague dawley yang dibagi menjadi kelompok baseline, kontrol negatif pakan, kontrol negatif pengolesan, perlakuan pemberian pakan, dan perlakuan pengolesan larutan teri. Setelah 15 hari, gigi dipotong dan dianalisa dengan EDX. Terdapat peningkatan kadar retensi fluor pada email gigi kelompok perlakuan dibandingkan kontrol negatif (p<0.05). Tidak terdapat perbedaan retensi fluor antar kelompok perlakuan (p>0.05). Maka pemberian substrat ikan teri jengki, baik lewat pengunyahan maupun pengolesan, meningkatkan retensi fluor pada email.

Usage of Indonesian resource like anchovy (Stolephorus insularis), which contains high fluoride concentration (CaF2), needs to be pursued as of topical fluoridative agent. This experimental laboratory in vivo research used 14 Sprague dawley rats which were divided into baseline, experimental (feeding and smearing), and their negative control groups. After 15 days, teeth were extracted and analyzed using EDX. There were increased fluoride retention on enamel of experimental groups compared to negative control groups (p<0.05). Fluoride retention levels in both experimental groups were not different (p>0.05). Thus, anchovy substrate application, either by chewing or smearing, increases fluoride retention on tooth enamel."
Depok: Universitas Indonesia, 2012
S44871
UI - Skripsi Membership  Universitas Indonesia Library
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Nur Rachmatyaz Sakinah
"Penelitian ini membuktikan efektifitas teri jengki (Stolephorus insularis) sebagai fluoridasi gigi dengan acuan kedalaman intrusi fluor. Digunakan metode eksperimental laboratorik in vivo. Subjek 14 ekor tikus Sprague dawley dibagi menjadi kelompok baseline, kontrol negatif pakan, kontrol negatif oles, metode pakan teri, dan metode oles larutan teri. Setelah perlakuan 15 hari, gigi dipotong transversal, diproses untuk uji intrusi fluor menggunakan mikroskop fluoresensi. Didapatkan hasil peningkatan intrusi fluor pada kelompok eksperimental dibandingkan kontrol negatif (p<0,05). Intrusi fluor metode oles lebih tinggi dibandingkan metode pakan (p <0,05). Jadi, aplikasi teri jengki, baik lewat pengunyahan maupun pengolesan, meningkatkan intrusi fluor pada email.

The effectiveness of anchovy (Stolephorus insularis) as a fluoridative agent is measured by depth of fluoride intrusion. This study used experimental laboratory method. 14 Sprague Dawley rats were divided into groups of baseline, experimental (feeding and smearing), and their negative controls. After 15 days, teeth were cut transversely and fluoride intrusions were observed using fluorescence microscope. There were increased fluoride intrusion in enamel of experimental groups compared to their negative controls (p<0.05). Fluoride intrusion of smearing group is higher than feeding group (p <0.05). Thus, application of anchovy substrate, either by chewing or smearing, increases fluoride intrusion in tooth enamel."
Depok: Universitas Indonesia, 2012
S45061
UI - Skripsi Membership  Universitas Indonesia Library
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"Background : Topical fluoridation recently is still the main caries prevention method. Fluoride application on enamel surface is aimed to convert the hydroxyapatite (HA) crystal to fluoroapatite (FA) or
hydroxyfluoroapatie (HFA) form. Fluoride retention and intrusion onto enamel after Fluoride application, therefore, are the most important factors to ensure the formation of FA and HFA crystals. Natural Fluoride
sources can be obtained from sea fishes, like teri (anchovy) fish. Teri medan (S baganensis) and teri jengki (S insularis) are the most pupolar teri fishes in Indonesia, and they are known 10 have high fluoride
content. 17-34 ppm. This research objectives are to measure fluoride retention and intrusion on enamel surface after application using teri medan and teri jengki substrate. Material and Method : 8 extracted
third impacted molars were used. During the research, those teeth are immersed in ono-ionic aquadest (aquadem). Each tooth were cut bucco-lingually and mesio-diastally to obtain 4 enamel specimens. The
specimens (totally 32) the divided into 3 major groups. 12 each for EDS group and intrusion groups and 8 for control. The EDS group divided Into 2 sub-groups for application with teri medan and teri jengki.
Similar procedure were done for intrusion and control groups. All EDS and intrusion specimens then immersed in the 5% teri substrate for 5 minutes. Flushed with aquadem, then stored in aquadem for 3 hours. Procedure above then repeated 26 times. Control specimens were immersed in saline for 5 minutes, before flush and stored in the aquadem solution. All the EDS specimens examinated using LEO
Scanning and micro analysis electron microscope. Intrusion groups evaluated with Olypus BX41TF fluorescence mocroscope. Results
uorescence microscope. Results fluoride retention for teri jengki groups is 5.28%, and for teri medan group is 3.26%, while for control group is 1.94%. Fluoride intrusion for teri jengki group is 11.48 um, teri
medan 8.74 um, and for control group is 0.84 um. Anova and Bonferroni test showed different result between experiment and control group and between teri jengki and teri medan group, both for retention
and intrusion examinations. Conclusion : based in this research, it can be concluded that teri jengki and teri medan fishes substrate give better result on fluoride retention and intrusion on enamel surface,
compared to the control group. Application using teri jengki substrale gives better fluoride retention and intrusion on enamel surface compare to the teri medan substrate appllication"
Journal of Dentistry Indonesia, 2003
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Artikel Jurnal  Universitas Indonesia Library
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Cininta Ayu Candani Kryandhari
"Penelitian dilakukan untuk mengetahui pengaruh perendaman dalam larutan kayu manis terhadap kekerasan mikro email gigi manusia dengan menggunakan Shimadzu Micro Hardness Tester HMV-2. Delapan spesimen gigi premolar atas manusia dibagi menjadi kelompok perendaman larutan 4% dan 12,5%, selama 60 menit, 120 menit, dan 180 menit. Pengukuran kekerasan menggunakan indenter Knoop, sebelum dan setelah perlakuan. Data dianalisis dengan Repeated ANOVA dan Independent T-Test. Perendaman dalam larutan 4% selama 60 menit dan 120 menit menurunkan kekerasan. Sebaliknya, perendaman selama 180 menit meningkatkan kekerasan. Perendaman dalam larutan 12,5% hingga180 menit menurunkan kekerasan. Perendaman gigi dalam larutan kayu manis dapat menyebabkan perubahan kekerasan.

This research was conducted to understand the effect of immersion of the human tooth enamel in cinnamon extract solution to the enamel microhardness using Shimadzu Micro Hardness Tester HMV-2. Eight specimens of maxillary premolar soaked in 4% and 12,5% solution for 60 minutes, 120 minutes, and 180 minutes. Hardness measurements using Knoop indenter performed before and after treatment. Data were analyzed by Repeated ANOVA and Independent T-Test. Immersion in 4% solution for 60 minutes and 120 minutes reduce microhardness. Soaking for 180 minutes will increase microhardness. Soaking in 12,5% solution for 180 minutes reduce microhardness. Enamel immersion may change microhardness.
"
Jakarta: Fakultas Kedokteran Gigi Universitas Indonesia, 2012
S45577
UI - Skripsi Membership  Universitas Indonesia Library
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Cut Yulian Fitriani
"Pendahuluan: Celah orofasial (COF) memerlukan perawatan palatoplasti untuk menutup fistula yang terdapat di palatum. Akan tetapi, pembentukan jaringan parut di area operasi berkaitan erat dengan gangguan pertumbuhan. Modifikasi teknik bedah dan pendekatan farmakologi telah diteliti untuk mengetahui efeknya terhadap pembentukan jaringan parut dan keberhasilan palatoplasti. Ikan gabus, Channa striata, merupakan salah satu ikan endemik Asia Tenggara yang secara empiris dipercaya dapat membantu penyembuhan, terutama pascamelahirkan. Sejumlah penelitian telah menunjukan efek dari ekstrak Channa striata terhadap penyembuhan luka, namun belum ada penelitian pada penyembuhan luka di palatum tikus. Penelitian ini bertujuan untuk melihat efek ekstrak Channa striata terhadap penyembuhan luka di palatum tikus secara histologis. Metode: Sebanyak 36 tikus Sprague dawley dibuatkan luka pada palatum dengan metode punch biopsy. Dari 36 tikus tersebut, dibagi dalam 3 kelompok, yaitu kelompok perlakuan dengan kombinasi topikal dan peroral ekstrak Channa striata, kelompok kontrol positif diberi gel gengigel dan suplemen vitamin C, dan kelompok kontrol negatif dirawat dengan gel tanpa bahan aktif. Kemudian dilakukan pengamatan pada hari ke-3, -7, dan - 14 setelah perlakuan secara klinis untuk mengamati luas luka mikroskopik. Sebanyak 4 tikus dari masing-masing perlakuan dinekropsi pada setiap hari pengamatan untuk dibuatkan preparat pengamatan histologis. Pewarnaan hematoksilin dan eosin dilakukan untuk mengamati panjang luka mikroskopik, reepitelisasi, dan angiogenesis, sedangkan pewarnaan Masson’s trichrome digunakan untuk mengamati kerapatan kolagen. Hasil dan Pembahasan: Pada hasil pengamatan ukuran luka, didapatkan bahwa terdapat perbedaan bermakna secara statistik (p<0,05) ukuran luka makroskopik pada hari ke-3 dan -14, reepitelisasi pada hari ke -7 dan -14, dan kerapatan kolagen pada hari ke-14. Di sisi lain, tidak terdapat perbedaan bermakna antarperlakuan pada pengamatan panjang luka mikroskopik dan angiogenesis. Ekstrak Channa striata terbukti dapat berdampak pada penyembuhan luka di palatum tikus. Kesimpulan: Berdasarkan penelitian ini, terlihat bahwa pemberian ekstrak Channa striata topikal dan peroral dapat mengurangi ukuran luka tikus, meningkatkan tingkat reepitelisasi, meningkatkan kerapatan kolagen, dan meningkatkan angiogenesis secara signifikan pada beberapa titik waktu yang diukur, tetapi efektivitasnya lebih rendah daripada gel gengigel dan vitamin C.

Introduction: Orofacial clefts (OFC) require palatoplasty treatment to close the fistulae present in the palate. However, scar tissue formation at the surgical site is closely associated with growth disturbance. Modification of surgical techniques and pharmacological approaches have been investigated for their effects on scar tissue formation and palatoplasty success. Snakehead fish, Channa striata, is one of the fish endemic to Southeast Asia that is empirically believed to aid healing, especially postpartum. A number of studies have shown the effect of Channa striata extract on wound healing, but there has been no study on wound healing in the palate of rats. This study aims to look at the effect of Channa striata extract on wound healing in the rat palate histologically. Methods: A total of 36 Sprague Dawley rats were wounded on the palate by punch biopsy method. The 36 rats were divided into 3 groups, namely the treatment group with topical and peroral combination of Channa striata extract, the positive control group was given gengigel gel and vitamin C supplement, and the negative control group was treated with gel without active ingredients. Then observations were made on day-3, -7, and -14 after clinical treatment to observe the microscopic wound area. A total of 4 rats from each treatment were necropsied on each observation day to make histological observation preparations. Hematoxylin and eosin staining was performed to observe microscopic wound length, re-epithelialization, and angiogenesis, while Masson's trichrome staining was used to observe collagen density. Results and Discussion: In the observation of wound size, there was a statistically significant difference (p<0.05) in macroscopic wound size on days 3 and 14, re-epithelialization on day 7 and 14, and collagen density on day 14. On the other hand, there was no significant difference between treatments in the observation of microscopic wound length and angiogenesis. Channa striata extract was shown to have an impact on wound healing in the rat palate. Conclusion: Based on this study, it was shown that topical and peroral administration of Channa striata extract can reduce the size of rat wounds, increase the rate of re-epithelialization, increase collagen density, and enhance angiogenesis significantly at several time points measured, but its effectiveness is lower than gengigel gel and vitamin C."
Jakarta: Fakultas Kedokteran Gigi Universitas Indonesia, 2024
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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"Topical fluoridation recently has become the method of choice in caries prevention. Flouride plays an important role not only in the formation of fluoroapatite, but also promoting enamel remineralization. Enamel remineralization occur when the enamel environtment supersaturated with calcium and phospate ions. When the pH level decrease, the rise of H ions, the hydroxyl of the apatite will be drawn out from the enamel, and substitute by fluoride ion, this condition will causes apatite breakdown and both calcium and phosphate will be released to the enamel environment. The release of those minerals, will cause supersaturation and promoting enamel remineralization. In the nature fluoride can be found in the sea fishes, such like teri (anchovy, Stolephorus sp) fishes. Teri fish has about 17-38 ppm of fluoride content. The high fluoride content of teri fish, lead this research to know the influence of it's application to the enamel surface on remineralization process, measured with enamel surface roughness and hardness tests. Seven enamel discs, 5 x 10 mm (W and L) obtained from 4 impacted third molars, were used in the research. One disc used as initial control, and 6 discs divided into 2 groups, used as experiment groups. All of the experimental discs demineralized using 50% phosphoric acid, then 3 of them were applied with teri substrate, wether other 3 discs applied with non ionic aquadest. All experimental discs, then immersed in the remineralization solution containing calcium phosphate stabilized with caseinphosphoptide. The cycle above repeated for 26 times. Analize of the specimens, were done using surfcom for enamel roughness and Buehler microhardness tester for surface hardness. Surface roughness of the teri group is 1,78 um compare to the initial group (215 um), and enamel surface microhardness of the teri group is (376 VHN), significantly differ from the control group, 358 VHN. Conclusion: Based on this research result, it can be concluded that : Teri fish substrate application on enamel surface causes the enhancement of enamel remineralization, as evaluated by surface roughness and micro hardness."
Journal of Dentistry Indonesia, 2003
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Artikel Jurnal  Universitas Indonesia Library
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Michelle Suryana
"ABSTRAK
Penelitian ini ditujukan untuk mengetahui dan membandingkan pengaruh pasta
gigi yang mengandung theobromine dan hydroxyapatite terhadap kekerasan mikro
email gigi setelah direndam dalam minuman berkarbonasi. Penelitian ini
menggunakan 21 spesimen mahkota gigi premolar satu rahang atas. Spesimen
direndam dalam minuman berkarbonasi kemudian disikat dengan pasta gigi yang
mengandung theobromine dan hydroxyapatite. Uji Kruskal-Wallis dan Mann-
Whitney menunjukkan perubahan kekerasan yang signifikan setelah penyikatan
selama 9 menit 20 detik menggunakan kedua pasta gigi pasca direndam dalam
minuman berkarbonasi selama 10 menit. Peningkatan nilai kekerasan mikro email
gigi pada kelompok hydroxyapatite lebih besar dibandingkan kelompok
theobromine (p<0,05).

ABSTRACT
This study is aimed to analyze the effect of theobromine and hydroxyapatite
toothpaste to enamel microhardess after immersion in carbonated drink. This
study uses 21 upper first premolar crown specimen which is immersed in
carbonated drink then brushed with theobromine and hydroxyapatite containing
toothpaste. Kruskal-Wallis and Mann-Whitney test shows significant difference of
microhardness after brushing for 9 minutes and 20 seconds using both toothpastes
after immersion in carbonated drink for 10 minutes with higher number in
hydroxyapatite group than theobromine group (p<0,05)."
Fakultas Kedokteran Gigi Universitas Indonesia, 2014
S-Pdf
UI - Skripsi Membership  Universitas Indonesia Library
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Muhamad Ihsan Pramadya Irawan
"Penelitian ini bertujuan untuk mengetahui pengaruh waktu paparan gel theobromine terhadap kekerasan permukaan email setelah demineralisasi dengan asam sitrat 1%. Spesimen email direndam asam sitrat 1% selama 2,5 menit lalu kemudian dipapar oleh gel theobromine 200 mg/l selama 16, 48 dan 96 menit. Nilai kekerasan email diuji menggunakan Knoop Microhardness Tester Shimadzu, Japan. Uji Wilcoxon dan Mann-Whitney menunjukkan bahwa terjadi penurunan nilai kekerasan email secara bermakna (p<0,05) setelah demineralisasi dengan asam sitrat 1% sebesar 35%-39%. Gel theobromine 200 mg/l dapat meningkatkan kekerasan email secara bermakna (p<0,05) yang telah didemineralisasi oleh asam sitrat 1%.

The aim of this study was to investigate the effect of different exposure time of theobromine gel on enamel microhardness after demineralization with 1% citric acid. Specimens were immersed in 1% citric acid solution for 2.5 minutes and then were exposed to theobromine gel 200 mg/l for 16, 48 and 96 minutes. Enamel microhardness value was tested using Knoop Microhardness Tester Shimadzu Japan. Wilcoxon and Mann-Whitney test showed significant reduction (p<0,05) of microhardness value for all specimens after demineralization with 1% citric acid about 35-39%. Theobromine gel could increase enamel microhardness significantly (p<0,05) after deminerlization with 1% citric acid."
Jakarta: Fakultas Kedokteran Gigi Universitas Indonesia, 2013
S45102
UI - Skripsi Membership  Universitas Indonesia Library
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