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Nurul Huda
"ABSTRAK
Cachexia merupakan masalah yang umum dialami oleh pasien kanker stadium
lanjut. Studi kualitatif dengan pendekatan fenomenologi dilakukan untuk
memperoleh gambaran tentang pengalaman cachexia pasien kanker stadium lanjut
dan keluarga yang merawat di RS Kanker Dharmais. Data studi diperoleh dari
lima partisipan pasien dan lima partisipan keluarga. Temuan memberikan
informasi rinci tentang pengalaman cachexia pada pasien kanker stadium lanjut
dan keluarga yang merawat dengan enam tema utama yang sama yaitu 1)
pengetahuan yang kurang tentang cachexia, 2) gangguan biopsikososial, 3)
perubahan pola makan, 4) perhatian perawat yang dirasakan kurang oleh pasien
dan keluarga, 5) kebutuhan akan pendidikan kesehatan dan 6) kebutuhan akan
peningkatan fasilitas kesehatan. Pada keluarga terdapat satu tema tambahan yaitu
terjadinya konflik dalam keluarga. Kemampuan dalam melakukan asuhan
keperawatan yang menyeluruh pada akhirnya akan meningkatan status nutrisi
pasien dan mengurangi konflik dalam keluarga.

Abstract
Cachexia is a common problem for cancer patient in end stage.
Phenomenologycal approach of qualitative study was conducted to get illustration
regarding experience of end stage cancer patient with cachexia and their families
who were involved during treatment in the Dharmais Cancer Hospital. Study
result gathered from five participants constituted of five patients and five families.
The current study showed detail information about experience of end stage cancer
patient with cachexia and their families within six main themes, namely : 1) lack
of knowledge about cachexia, 2) Biopsychosocial disturbances, 3) diet pattern
disturbances, 4) lack of attention from nurse, 5) in need of health education and 6)
in need of improvement of health facilities. Particularly within families member
there were additional main theme, namely : conflict in family. Abilities in
establishing holistic nursing care will lead to increase patient nutrition level and
decrease conflict within families."
Fakultas Ilmu Keperawatan Universitas Indonesia, 2012
T30951
UI - Tesis Open  Universitas Indonesia Library
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Agus Rahmadi
"ABSTRAK
Kanker paru merupakan kanker yang paling banyak dijumpai sebagai salah satu penyebab kematian didunia. Kaheksia sering terjadi pada pasien kanker paru dengan tingkat survival yang rendah. Kaheksia ditandai dengan penurunan berat badan yang berdampak pada berkurangnya jaringan lemak dan otot rangka, kelelahan dan inflamasi sistemik. Sitokin berhubungan dengan terjadinya inflamasi sistemik. Salah satu sitokin yang berperan adalah IL ndash;6. IL ndash;6 dapat menstimulasi pembentukan protein fase akut yang berperan menyebabkan penurunan berat badan pada kaheksia. Seperti diketahui bahwa miRNA berperan dalam proses myogenesis. Salah satu myomiR yang berperan adalah miRNA ndash;206. MyomiR ndash;206 merupakan kelompok myomiR yang terekspresikan pada otot rangka. MiRNA berperan penting sebagai modulator ekspresi gen, namun mekanisme terjadinya atropi otot pada kaheksia belum banyak diketahui. Desain penelitian ini adalah penelitian cross sectional. Tujuan penelitian ini adalah untuk mengetahui ekspresi myomiR ndash; 206 pada pasien kanker paru yang mengalami kaheksia dan kaitannya dengan IL ndash;6. Ekspresi miRNA diukur dalam serum darah pasien dengan menggunakan RT-qPCR. Hasil penelitian menunjukkan terdapat perbedaan ekspresi myomiR ndash;206 antara kelompok pre kaheksia dengan kelompok kaheksia namun tidak bermakna secara statistik. Sedangkan perbedaan IL ndash;6 antara kelompok prekaheksia dengan kaheksia menunjukkan hubungan bermakna secara statistik. Dapat disimpulkan bahwa terdapat perbedaan ekspresi myomiR ndash;206 pada pasien kanker paru yang mengalami kaheksia namun tidak bermakna secara statistik dan berkaitan dengan IL ndash;6.

ABSTRACT
Lung cancer is the leading cause of cancer related deaths worldwide. Cachexia are frequently observed in lung cancer patients and associated with poor survival. Cachexia is characterized by a significant reduction in body weight resulting predominantly from loss of adipose tissue and skeletal muscle, fatique and systemic Inflamation. Cytokines are related to systemic inflammation . One of these cytokines is IL ndash 6. IL ndash 6 stimulates the synthesis of acute phase proteins are important in promoting weight loss in cachexia. In Additional, miRNAs have been identified and shown to have an important role in myogenesis. One of these myomiRs is miRNA ndash 206. MyomiR ndash 206 is expressed in skeletal muscle. MiRNAs are important modulators of gene expression but their role the atrophy muscle in cachexia is unknown.This research was a cross sectional study. The aim of this study was to see expression of myomiR ndash 206 in lung cancer patient with cachexia in correlation with IL ndash 6. MicroRNA expression was measured from serum of blood using RT qPCR.. These results, There was difference expression of myomiR ndash 206 in lung cancer patient between precachexia and cachexia but there was no significant in statistic. There was significant in IL ndash 6 between precachexia and cachexia. Our results suggest that there was difference expression of myomiR ndash 206 in lung cancer patient with cachexia but there was no significant statistic and associated with IL ndash 6."
2017
T55638
UI - Tesis Membership  Universitas Indonesia Library
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Indah Suciarti
"Trastuzumab adalah produk bioteknologi terbaru dalam pengobatan kanker payudara. Antibodi monoklonal ini bekerja langsung pada targetnya yaitu reseptor HER2 (Human Epidermal growth factor Receptor-2). Harga obat ini sangat mahal. Penelitian ini bertujuan untuk mengamati pola pengobatan 61 data rekam medis pasien kanker payudara yang memiliki HER2+ di Rumah Sakit Kanker Dharmais Jakarta selama periode September 2003 hingga Maret 2006. Hasil dari uji chi-square menggunakan likelihood ratio menunjukkan bahwa ada hubungan antara penjamin biaya pengobatan terhadap jenis pengobatan (p< 0,05). Sedangkan tidak ada hubungan antara pendidikan dengan jenis pengobatan (p>0,05). Hasil survei deskriptif menunjukkan bahwa kelompok usia 40 - 49 tahun memiliki persentase kanker payudara yang memiliki HER2+ terbesar (36,1 %), stadium yang tertinggi persentasenya adalah stadium IV (19,7 %), serta pasien yang mempunyai riwayat kanker keluarga adalah sebanyak 10 dari 17 pasien (58,82 %), sedangkan 44 pasien tidak diketahui datanya."
Depok: Universitas Indonesia, 2006
S32455
UI - Skripsi Membership  Universitas Indonesia Library
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Cherlin, Andrew J.
London: McGraw-Hill, 2002
306.85 Che p
Buku Teks  Universitas Indonesia Library
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Siojang, Baso
Sulawesi Tengah: P-2 NB, 1998,
306 Fun (2)
Buku Teks  Universitas Indonesia Library
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Nuryanih
"[ABSTRAK
Perawat memegang peranan penting dalam pemberian asuhan keperawatan serta mendampingi
pasien dengan kanker ginekologi selama 24 jam. Pada pelaksanaan, belum semua perawat
melakukan pengkajian psikoseksual ketika memberikan asuhan pelayanan keperawatan untuk
menggali masalah seksual akibat terapi yang dialami oleh pasien kanker. Penelitian ini bertujuan
untuk mengeksplorasi pengalaman perawat yang bekerja diunit ongkologi dalam mendiskusikan
isu seksual dengan pasien dan penyintas kanker ginekologi. Secara keseluruhan fenomena yang
didapatkan dalam penelitian ini adalah suatu gambaran pengalaman perawat dalam
mendiskusikan isu seksual dengan pasien kanker ginekologi. Penelitian dengan metode kualitatif
dengan desain fenomenologi ini melibatkan sampel sepuluh partisipan. Analisa hasil penelitian
dilakukan dengan cara analisa isi dengan menyimpulkan pernyataan partisipan menjadi tema
dalam penelitian. Penelitian ini menemukan lima tema utama yang berkaitan dengan pengalaman
perawat dalam mendiskusikan isu seksual dengan pasien kanker ginekologi yaitu persepsi
perawat tentang pelayanan psikoseksual, hambatan yang ditemukan perawat ketika
mendiskusikan isu seksual dengan pasien kanker ginekologi, menemukan masalah yang
mengganggu seksualitas pada pasien kanker ginekologi, cara/upaya perawat memperoleh
dukungan dalam membantu masalah psikoseksual pada pasien kanker ginekologi, kebutuhan
perawat terhadap implementasi pelayanan psikoseksual pada pasien kanker ginekologi.
Pelayanan psikoseksual pada pasien kanker ginekologi dapat ditingkatkan dengan adanya diskusi
isu seksual dengan pasien kanker ginekologi. Perawat diharapkan dapat melakukan pengkajian
psikoseksual di dalam pemberian asuhan keperawatan pada pasien kanker ginekologi.

ABSTRACT
Nurses play an important role in providing nursing care as well as assisting gynecologic cancer
patients for 24 hours. In fact, not all nurses do a psychosexual assessment when providing
nursing care in order to explore sexual problems related to the cancer therapy experienced by the
patients. This study aimed to explore the experiences of nurses who work in oncology unit in
discussing sexual issues with the patients and survivors of gynecologic cancer. Overall
phenomenon obtained in this study was an overview of nurses? experiences in discussing sexual
issues with gynecologic cancer patients. This study applied a qualitative method with
phenomenological design. The samples were ten participants. The results were analyzed using
content analysis by concluding the participants? statements to become the research themes. This
study identified five main themes related to nurses? experiences in discussing sexual issues with
gynecologic cancer patients, including nurses? perceptions of psychosexual services, the
obstacles found by nurses when discussing sexual issues with gynecologic cancer patients,
finding problems that interfere with sexuality in gynecologic cancer patients, nurses? attempts to
obtain supports in helping psychosexual problems of gynecologic cancer patients, nurses? needs
to the implementation of psychosexual services for gynecologic cancer patients. Psychosexual
services for gynecologic cancer patients can be improved by the presence of sexual issues
discussion with gynecologic cancer patients. Nurses are expected to do a psychosexual
assessment in providing nursing care to gynecologic cancer patients.;Nurses play an important role in providing nursing care as well as assisting gynecologic cancer
patients for 24 hours. In fact, not all nurses do a psychosexual assessment when providing
nursing care in order to explore sexual problems related to the cancer therapy experienced by the
patients. This study aimed to explore the experiences of nurses who work in oncology unit in
discussing sexual issues with the patients and survivors of gynecologic cancer. Overall
phenomenon obtained in this study was an overview of nurses? experiences in discussing sexual
issues with gynecologic cancer patients. This study applied a qualitative method with
phenomenological design. The samples were ten participants. The results were analyzed using
content analysis by concluding the participants? statements to become the research themes. This
study identified five main themes related to nurses? experiences in discussing sexual issues with
gynecologic cancer patients, including nurses? perceptions of psychosexual services, the
obstacles found by nurses when discussing sexual issues with gynecologic cancer patients,
finding problems that interfere with sexuality in gynecologic cancer patients, nurses? attempts to
obtain supports in helping psychosexual problems of gynecologic cancer patients, nurses? needs
to the implementation of psychosexual services for gynecologic cancer patients. Psychosexual
services for gynecologic cancer patients can be improved by the presence of sexual issues
discussion with gynecologic cancer patients. Nurses are expected to do a psychosexual
assessment in providing nursing care to gynecologic cancer patients.;Nurses play an important role in providing nursing care as well as assisting gynecologic cancer
patients for 24 hours. In fact, not all nurses do a psychosexual assessment when providing
nursing care in order to explore sexual problems related to the cancer therapy experienced by the
patients. This study aimed to explore the experiences of nurses who work in oncology unit in
discussing sexual issues with the patients and survivors of gynecologic cancer. Overall
phenomenon obtained in this study was an overview of nurses’ experiences in discussing sexual
issues with gynecologic cancer patients. This study applied a qualitative method with
phenomenological design. The samples were ten participants. The results were analyzed using
content analysis by concluding the participants’ statements to become the research themes. This
study identified five main themes related to nurses’ experiences in discussing sexual issues with
gynecologic cancer patients, including nurses’ perceptions of psychosexual services, the
obstacles found by nurses when discussing sexual issues with gynecologic cancer patients,
finding problems that interfere with sexuality in gynecologic cancer patients, nurses’ attempts to
obtain supports in helping psychosexual problems of gynecologic cancer patients, nurses’ needs
to the implementation of psychosexual services for gynecologic cancer patients. Psychosexual
services for gynecologic cancer patients can be improved by the presence of sexual issues
discussion with gynecologic cancer patients. Nurses are expected to do a psychosexual
assessment in providing nursing care to gynecologic cancer patients.;Nurses play an important role in providing nursing care as well as assisting gynecologic cancer
patients for 24 hours. In fact, not all nurses do a psychosexual assessment when providing
nursing care in order to explore sexual problems related to the cancer therapy experienced by the
patients. This study aimed to explore the experiences of nurses who work in oncology unit in
discussing sexual issues with the patients and survivors of gynecologic cancer. Overall
phenomenon obtained in this study was an overview of nurses’ experiences in discussing sexual
issues with gynecologic cancer patients. This study applied a qualitative method with
phenomenological design. The samples were ten participants. The results were analyzed using
content analysis by concluding the participants’ statements to become the research themes. This
study identified five main themes related to nurses’ experiences in discussing sexual issues with
gynecologic cancer patients, including nurses’ perceptions of psychosexual services, the
obstacles found by nurses when discussing sexual issues with gynecologic cancer patients,
finding problems that interfere with sexuality in gynecologic cancer patients, nurses’ attempts to
obtain supports in helping psychosexual problems of gynecologic cancer patients, nurses’ needs
to the implementation of psychosexual services for gynecologic cancer patients. Psychosexual
services for gynecologic cancer patients can be improved by the presence of sexual issues
discussion with gynecologic cancer patients. Nurses are expected to do a psychosexual
assessment in providing nursing care to gynecologic cancer patients., Nurses play an important role in providing nursing care as well as assisting gynecologic cancer
patients for 24 hours. In fact, not all nurses do a psychosexual assessment when providing
nursing care in order to explore sexual problems related to the cancer therapy experienced by the
patients. This study aimed to explore the experiences of nurses who work in oncology unit in
discussing sexual issues with the patients and survivors of gynecologic cancer. Overall
phenomenon obtained in this study was an overview of nurses’ experiences in discussing sexual
issues with gynecologic cancer patients. This study applied a qualitative method with
phenomenological design. The samples were ten participants. The results were analyzed using
content analysis by concluding the participants’ statements to become the research themes. This
study identified five main themes related to nurses’ experiences in discussing sexual issues with
gynecologic cancer patients, including nurses’ perceptions of psychosexual services, the
obstacles found by nurses when discussing sexual issues with gynecologic cancer patients,
finding problems that interfere with sexuality in gynecologic cancer patients, nurses’ attempts to
obtain supports in helping psychosexual problems of gynecologic cancer patients, nurses’ needs
to the implementation of psychosexual services for gynecologic cancer patients. Psychosexual
services for gynecologic cancer patients can be improved by the presence of sexual issues
discussion with gynecologic cancer patients. Nurses are expected to do a psychosexual
assessment in providing nursing care to gynecologic cancer patients.]"
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2014
T42854
UI - Tesis Membership  Universitas Indonesia Library
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Faqih Ruhyanudin
"Kanker adalah pertumbuhan sel baru yang tidak terkontrol, mampu menyebar dan menginvasi sehingga mengancam kehidupan. Insiden kanker dilaporkan dari tahun ke tahun terjadi peningkatan. Berbagai upaya telah dilakukan untuk menurunkan morbiditas dan mortalitas kanker.
Karya Ilmiah Akhir (KIA) ini adalah sebagai laporan praktik residensi keperawatan medikal bedah peminatan onkologi di RS Kanker Dharmais Jakarta. Karya ilmiah ini berisi tentang: (1) penerapan teori Peaceful End of Life (PEOL) pada pasien kanker tyroid, (2) penerapan RIDcancerPain untuk menurunkan nyeri sebagai Evidence Based Nursing Practice (EBNP), (3) proyek inovasi integrasi ESAS kedalam pengkajian pasien rawat inap.
Kesimpulan: bahwa teori peaceful end of life tepat digunakan dalam perawatan paliatif pasien kanker. Intervensi edukasi dengan pendekatan RIDcancerPain dapat digunakan sebagai salah satu alternatif pilihan manajemen nyeri nonfarmakologi. Instrumen ESAS memerlukan kompilasi dengan instrumen pengkajian lain agar mendapatkan data yang komprehensif.

Cancer is an uncontrolled new growth of the cell which capable of metastasis and invasion that threatens host survival. The incidence of cancer reported from year to year there was an increase. Various attempts have been made to decrease the morbidity and mortality of cancer.
Method: The paper is a report medicalsurgical nursing practice residency specialization in oncology at Dharmais Cancer Hospital in Jakarta. Its consists of: (1) a report on the nursing care of thyroid cancer patients with peaceful end of life theory approach focused on not being in pain, experience of comfort, experience of dignity and respect, being at peace, and closeness to significant others. (2) the application of RIDcancerPain to reduce pain as the evidence based nursing practice (EBNP), (3) the innovation project of the integration of an ESAS into assessment inpatients.
Conclusion: The peaceful end of life theory is suitable for used in the palliative care. Educational intervention with RIDcancerPain approach can be used as an alternative of the non-pharmacological pain management. ESAS is requires compilation with other assessment instruments in order to obtain comprehensive data.
"
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2014
SP-Pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Ramadhaniyah
"ABSTRAK
Remaja merupakan masa peralihan yang memiliki proses perkembangan yang
berbeda dengan usia anak-anak dan dewasa. Adanya diagnosis kanker pada masa
remaja akan menimbulkan berbagai macam respon fisik dan respon psikologis
bagi mereka. Tujuan penelitian ini ingin mengeksplorasi pengalaman dan
mekanisme adaptasi remaja yang didiagnosis penyakit kanker. Penelitian ini
menggunakan metode kualitatif dengan pendekatan fenomenologi deskriptif.
Partisipan penelitian ini terdiri dari tujuh orang remaja dengan penyakit kanker.
Pengambilan data dilakukan dengan wawancara mendalam berdasarkan tujuan
penelitian. Analisis data hasil wawancara menggunakan tahapan analisis menurut
Colaizzi. Temuan hasil penelitian ini antara lain: respon dan adaptasi fisiologis,
respon dan adaptasi psikologis, dimensi kebutuhan, dimensi sosial, dimensi
konsep diri, dimensi aktivitas, serta harapan dan upaya untuk sembuh.
Rekomendasi hasil penelitian ini ditujukan pada perawat anak yang mungkin akan
berhubungan langsung dengan remaja penderita kanker dalam membantu mereka
untuk menggunakan strategi yang adaptif dalam menghadapi diagnosis kanker
dan efek terapi kanker.

Abstract
Adolescence is a transition period which has a different developmental process
with childhood and adults period. Cancer diagnosis during adolescence can cause
a variety of physical and psychological responses. The purpose of this study is to
explore the experience and adaptation mechanisms of adolescents who diagnosed
with cancer. This study use a qualitative method with descriptive
phenomenological approach. Participants of this study consisted of seven
adolescents with cancer. Data is collected by in-depth interviews. Data is analyzed
according to Colaizzi?s stage data analysis. The findings of this study include:
response and physiological adaptation, response and adaptation of psychological,
adolescence with cancer needs, social dimension, self concept dimension,
dimensions of activity, as well as the hopes and efforts of adolescent cancer to
heal. Recommendations of this study is aimed at pediatric nursing to help
adolescent with cancer in use an adaptive strategy in dealing with cancer
diagnosis and side effects of cancer therapy."
2012
T30942
UI - Tesis Open  Universitas Indonesia Library
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"Pentagamavunon-0 or [2,5-bis-(4-hydroxy-3-methoxy- benzylidene), was determined on its on its cytotoxicity,antiproliferative and antiangiogenesis effects in comparation to the effect of its analogue,curcumin(1,7-bis-(hydroxy-3-methoxyphenyl)-1,6 heptadiena-3,5-dion) againts 17-b-estradiol(E) induced human breast cancer cells T47D"
610 SKJ 19:1 (2006)
Artikel Jurnal  Universitas Indonesia Library
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