The objective of this research was to know: the effect of learning strategy, academic ability, as well as the interaction of learning strategy and academic ability on metacognitive ability and learning outcome. The statistic analysis used were Anacova and LSD. Learning strategy process consistency test was similarity test of regression equation. The conclusion of the research were: (1) learning strategy didn’t affect metacognitive ability, (2) learning strategy affected cognitive learning outcome, in this case multistrategy was the most constructive. (3) academic ability didn’t affect metacognition and cognitive learning outcome, (4) the interaction of learning strategy and academic ability did not affect metacognitive ability, but the best interaction was PBMP combine with Script with and academic ability, and (5) the interaction of learning strategy and academic ability did not affect cognitive learning outcome, but the best interaction was PBMP combine with TPS and low academic ability.