ABSTRAKTelah dilakukan penelitian untuk mengetahui pengaruh pemberian fortifikan
NaFeEDTA dalam tepung tempe dan susu kedelai terhadap kadar natrium plasma
darah tikus (Rattus norvegicus L.) jantan galur Sprague Dawley. Sebanyak 25
ekor tikus dibagi ke dalam 5 kelompok: kelompok kontrol 1 (KK1) yang diberi
CMC 0,5%, kelompok kontrol 2 (KK2) yang diberi tepung tempe atau susu
kedelai, dan tiga kelompok perlakuan (KP1, KP2, KP3) yang diberi tepung tempe
atau susu kedelai dengan fortifikan NaFeEDTA dosis 1,35 mg Fe/ kgBB; 2,7 mg
Fe/ kgBB; 5,4 mg Fe/ kgBB selama 21 hari berturut-turut. Penentuan kadar
natrium plasma dengan alat AES (Atomic Emission Spectroscopy). Hasil uji
Anava satu arah (P > 0,05) menunjukkan tidak ada pengaruh nyata pemberian
fortifikan NaFeEDTA dalam tepung tempe dan susu kedelai terhadap kadar
natrium antar kelompok perlakuan. Kadar natrium plasma pada T21 dengan bahan
uji tepung tempe dan susu kedelai tetap berada pada rentang normal antara 0,456
mg/ml -- 0,586 mg/ml.
ABSTRACTThe effect of NaFeEDTA fortificant inserted in tempeh flour and soy milk intake
on plasma sodium concentration in male Sprague-Dawley rats (Rattus norvegicus
L.) had been studied. Twenty five rats were divided into five groups: control
group 1 (KK1) was administered with CMC 0.5%, control group 2 (KK2) was
administered with tempeh flour or soy milk; three treatment groups (KP1, KP2,
KP3) were administered with tempeh flour or soy milk added with fortificant
NaFeEDTA 1.35 mg Fe/kgBw; 2.7 mg Fe/kgBw; 5.4 mg Fe/kgBw consecutive
for 21 days. Plasma sodium concentration was measured by AES (Atomic
Emission Spectroscopy). One way Anova test (P > 0.05) showed there is no
significant effect of fortificant NaFeEDTA inserted in tempeh flour and soy milk
intake on plasma sodium concentration in all treatment groups. Plasma sodium
concentration on T21 which was administered with tempeh flour and soy milk
remains in normal range between 0.456 mg/ml ? 0.586 mg/ml.