The article talks about four principles of biomedical ethics, respect for autonomy, non-maleficence, beneficence, and justice. The methodology which was a critique against the present biomedical ethics, was formulated in 1979 by Tom Beauchamp and James Childress. By applying principlism, the paramedics have to constantly understand three components: application, balancing efforts, and specification. The four fundamental principles of biomedical ethics (autonomy, non-maleficence, beneficence, and justice) have proposed a useful methodology to deal with cases, such as the doctor-patient relations, the use of life support systems, or any research using man as subject.