The present book collects the contributions from the meeting, mixing styles, arguments, topics, history and philosophy of science, modern biology and epistemology . This kind of inter-disciplinary approach may appear erratic, but it conveys flashes of lights on the changing scene where the theory of evolution plays. This is in line with the idea to reopen the file of the two cultures, looking at shared problems, which are not yet really the third culture invoked by Charles Percy Snow half a century ago, but they can foster it, at least in such a pivotal domain as evolution.