This volume comprises the proceedings of the 2010 International Symposium of the ICA Commission on the History of Cartography. The nineteen papers reflect the research interests of the Commission which span the period from the Enlightenment to the evolution of Geographical Information Science. The volume, which reflects some co-operation with the ICA Commission on Maps and Society and the United States Geological Survey (USGS), contains regional studies on cartographic endeavours in Northern America, Brazil, and Southern Africa. The ICA Commission on Maps and Society participated as its field of study often overlaps with that of the ICA Commission on the history of cartography.