ABSTRAKMerokok berbahaya bagi perokok aktif maupun perokok pasif (Aditama, 2001).
Asap rokok mengandung nikotin yang dapat memicu aktivitas kelenjar tiroid pada
manusia (Utiger, 1998). Wanita lebih rentan mengalami hipertiroid (Greenspan
and Baxter, 1994). Penelitian ini bertujuan untuk mengetahui hubungan antara
status merokok dengan kejadian hipertiroid pada pasien wanita usia subur di
Klinik Balai Litbang GAKI Magelang tahun 2013-2014. Penelitian dilakukan
dengan disain kasus-kontrol. Penelitian melibatkan 51 responden pasien wanita
usia subur penderita hipertiroid dan 102 responden pasien wanita usia subur
dengan fungsi tiroid normal (eutiroid). Pengumpulan data dilakukan pada status
merokok, umur, penggunaan kontrasepsi hormonal, melahirkan 1 tahun terakhir,
tingkat stres, dan kebiasaan penggunaan garam beriodium rumah tangga
responden. Data dianalisa menggunakan uji regresi logistik. Pasien wanita usia
subur terpajan asap rokok baik perokok aktif atau pasif berisiko mengalami
hipertiroid 2,05 kali dari risiko pasien wanita usia subur di Klinik Balai Litbang
GAKI Magelang setelah dikontrol variabel kontrasepsi hormonal dan tingkat
stres. Menggunakan kontrasepsi hormonal menurunkan risiko hipertiroid,
sedangkan stres berat meningkatkan risiko hipertiroid. Wanita usia subur
hendaknya menghindari pajanan asap rokok dan melakukan manajemen stres
untuk mengurangi faktor risiko hipertiroid.
ABSTRACTSmoking is harmful to the active smokers and passive smokers (Aditama, 2001).
Tobacco smoke contains nicotine, chemical that are known can lead
hyperthyroidism in human (Utiger, 1998). This study aimed to determine the
relationship between smoking status on hyperthyroidism in patients of
childbearing age women in the Clinic of IDD (Iodine Deficiency Disorders)
Research Center, Magelang in 2013-2014. The study was conducted with a casecontrol
design. The study involved 51 childbearing-age women patients with
hyperthyroidism patients and 102 childbearing-age women patients with normal
thyroid function (euthyroid). Data collection was conducted on smoking status,
age, hormonal contraceptive use, giving birth in the past one year, the level of
stress, and the habits of the use of iodized salt in the household. Data were
analyzed using logistic regression. Chiilbearing-age women patients who were
active/passive smokers at risk of hyperthyroidism 2.05 times the risk of
childbearing-age women patients in the Clinic of Iodine Deficiency Disorders
(IDD) Research Center, Magelang after controlled by hormonal contraceptives
and stress levels variables. Use of hormonal contraceptives reduce the risk of
hyperthyroidism, whereas severe stress increases the risk of hyperthyroidism.
Childbearing-age women should avoid exposure to cigarette smoke and do stress
management to reduce risk factors for hyperthyroidism.